Nmnat1 (nicotinamide nucleotide adenylyltransferase 1) - Rat Genome Database

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Gene: Nmnat1 (nicotinamide nucleotide adenylyltransferase 1) Rattus norvegicus
Analyze
Symbol: Nmnat1
Name: nicotinamide nucleotide adenylyltransferase 1
RGD ID: 1310996
Description: Predicted to enable adenylyltransferase activity; identical protein binding activity; and protein ADP-ribosyltransferase-substrate adaptor activity. Involved in negative regulation of apoptotic DNA fragmentation; negative regulation of neuron apoptotic process; and positive regulation of MAPK cascade. Predicted to be located in nuclear body. Predicted to be part of chromatin. Predicted to be active in nucleus. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Orthologous to human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; monoterpenoid biosynthetic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC298653; MGC156478; nicotinamide mononucleotide adenylyl transferase 1; nicotinamide mononucleotide adenylyltransferase 1; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85165,193,301 - 165,211,213 (-)NCBIGRCr8
mRatBN7.25159,910,242 - 159,928,201 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5159,910,242 - 159,928,180 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5162,626,872 - 162,644,786 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05164,446,857 - 164,464,893 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05164,403,219 - 164,421,255 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05166,409,460 - 166,430,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,409,461 - 166,430,254 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05170,057,406 - 170,076,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45166,548,899 - 166,567,266 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15166,560,236 - 166,569,740 (-)NCBI
Celera5158,179,840 - 158,197,813 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISO)
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways. Houtkooper RH, etal., Endocr Rev. 2010 Apr;31(2):194-223. doi: 10.1210/er.2009-0026. Epub 2009 Dec 9.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy. Sasaki Y, etal., J Neurosci. 2006 Aug 16;26(33):8484-91. doi: 10.1523/JNEUROSCI.2320-06.2006.
11. Nmnat 1: a Security Guard of Retinal Ganglion Cells (RGCs) in Response to High Glucose Stress. Zhou RM, etal., Cell Physiol Biochem. 2016;38(6):2207-18. doi: 10.1159/000445576. Epub 2016 May 17.
Additional References at PubMed
PMID:11027696   PMID:11248244   PMID:12477932   PMID:15381699   PMID:16118205   PMID:17074042   PMID:18783366   PMID:21516116   PMID:21630459   PMID:22365601   PMID:25416956   PMID:25502805  
PMID:27257257   PMID:27735788   PMID:31515488  


Genomics

Comparative Map Data
Nmnat1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85165,193,301 - 165,211,213 (-)NCBIGRCr8
mRatBN7.25159,910,242 - 159,928,201 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5159,910,242 - 159,928,180 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5162,626,872 - 162,644,786 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05164,446,857 - 164,464,893 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05164,403,219 - 164,421,255 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05166,409,460 - 166,430,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,409,461 - 166,430,254 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05170,057,406 - 170,076,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45166,548,899 - 166,567,266 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15166,560,236 - 166,569,740 (-)NCBI
Celera5158,179,840 - 158,197,813 (-)NCBICelera
Cytogenetic Map5q36NCBI
NMNAT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819,942,923 - 9,996,892 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19,943,428 - 9,985,501 (+)EnsemblGRCh38hg38GRCh38
GRCh37110,002,981 - 10,045,556 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619,926,073 - 9,968,143 (+)NCBINCBI36Build 36hg18NCBI36
Build 3419,937,752 - 9,977,979NCBI
Celera19,114,519 - 9,156,598 (+)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef19,158,939 - 9,200,537 (+)NCBIHuRef
CHM1_119,992,303 - 10,034,914 (+)NCBICHM1_1
T2T-CHM13v2.019,485,828 - 9,539,839 (+)NCBIT2T-CHM13v2.0
Nmnat1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394149,552,026 - 149,569,667 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4149,552,029 - 149,569,659 (-)EnsemblGRCm39 Ensembl
GRCm384149,467,569 - 149,485,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4149,467,572 - 149,485,202 (-)EnsemblGRCm38mm10GRCm38
MGSCv374148,842,896 - 148,859,251 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364148,312,587 - 148,328,942 (-)NCBIMGSCv36mm8
Celera4151,732,264 - 151,748,554 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map479.47NCBI
Nmnat1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554863,637,794 - 3,655,598 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554863,637,794 - 3,655,744 (-)NCBIChiLan1.0ChiLan1.0
NMNAT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21218,229,238 - 218,276,060 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11216,879,808 - 216,921,711 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v018,712,798 - 8,753,027 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.119,942,491 - 9,982,369 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl19,942,491 - 9,982,364 (+)Ensemblpanpan1.1panPan2
NMNAT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,122,379 - 63,152,078 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,122,498 - 63,151,661 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha563,137,192 - 63,167,170 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0563,348,554 - 63,379,178 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl563,349,103 - 63,379,006 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1563,369,458 - 63,399,943 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0563,209,144 - 63,239,504 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0563,612,791 - 63,643,286 (+)NCBIUU_Cfam_GSD_1.0
Nmnat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505833,377,149 - 33,406,723 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366233,870,031 - 3,891,849 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366233,862,234 - 3,891,849 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NMNAT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl670,272,014 - 70,310,707 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1670,271,296 - 70,307,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2664,326,981 - 64,334,151 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NMNAT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120121,790,836 - 121,797,043 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605425,709,816 - 25,751,201 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nmnat1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248182,573,498 - 2,580,095 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248182,575,476 - 2,591,423 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nmnat1
104 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:503
Count of miRNA genes:244
Interacting mature miRNAs:294
Transcripts:ENSRNOT00000048914
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

Markers in Region
D5Uwm49  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25159,910,699 - 159,910,952 (+)MAPPERmRatBN7.2
Rnor_6.05166,409,918 - 166,410,170NCBIRnor6.0
Rnor_5.05170,057,864 - 170,058,116UniSTSRnor5.0
RGSC_v3.45166,549,356 - 166,549,609RGDRGSC3.4
RGSC_v3.45166,549,357 - 166,549,609UniSTSRGSC3.4
RGSC_v3.15166,559,544 - 166,559,797RGD
Celera5158,180,298 - 158,180,550UniSTS
Cytogenetic Map5q36UniSTS
RH134246  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25159,910,325 - 159,910,538 (+)MAPPERmRatBN7.2
Rnor_6.05166,409,544 - 166,409,756NCBIRnor6.0
Rnor_5.05170,057,490 - 170,057,702UniSTSRnor5.0
RGSC_v3.45166,548,983 - 166,549,195UniSTSRGSC3.4
Celera5158,179,924 - 158,180,136UniSTS
RH 3.4 Map51116.8UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 34 20 15 3 15 2 51 24 29 5
Low 9 37 26 16 26 8 9 23 11 12 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000048914   ⟹   ENSRNOP00000041982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5159,910,254 - 159,928,180 (-)Ensembl
Rnor_6.0 Ensembl5166,409,461 - 166,430,254 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100229   ⟹   ENSRNOP00000097390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5159,910,297 - 159,927,698 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105546   ⟹   ENSRNOP00000083340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5159,910,242 - 159,928,151 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113614   ⟹   ENSRNOP00000076779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5159,910,242 - 159,920,124 (-)Ensembl
RefSeq Acc Id: NM_001037556   ⟹   NP_001032645
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,193,301 - 165,211,213 (-)NCBI
mRatBN7.25159,910,242 - 159,928,154 (-)NCBI
Rnor_6.05166,409,460 - 166,430,254 (-)NCBI
Rnor_5.05170,057,406 - 170,076,545 (-)NCBI
RGSC_v3.45166,548,899 - 166,567,266 (-)RGD
Celera5158,179,840 - 158,197,813 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239429   ⟹   XP_006239491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,193,301 - 165,209,561 (-)NCBI
mRatBN7.25159,910,242 - 159,927,619 (-)NCBI
Rnor_6.05166,410,350 - 166,429,735 (-)NCBI
Rnor_5.05170,057,406 - 170,076,545 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593311   ⟹   XP_017448800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,193,301 - 165,203,071 (-)NCBI
mRatBN7.25159,910,242 - 159,920,043 (-)NCBI
Rnor_6.05166,410,350 - 166,423,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109700   ⟹   XP_038965628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,193,301 - 165,210,873 (-)NCBI
mRatBN7.25159,910,242 - 159,927,875 (-)NCBI
RefSeq Acc Id: XM_039109702   ⟹   XP_038965630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,193,301 - 165,200,378 (-)NCBI
mRatBN7.25159,910,242 - 159,917,330 (-)NCBI
RefSeq Acc Id: XM_039109704   ⟹   XP_038965632
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,193,301 - 165,209,561 (-)NCBI
mRatBN7.25159,911,657 - 159,927,624 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001032645   ⟸   NM_001037556
- UniProtKB: A0JPJ0 (UniProtKB/TrEMBL),   E9PSK8 (UniProtKB/TrEMBL),   Q32WF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239491   ⟸   XM_006239429
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZV91 (UniProtKB/TrEMBL),   A0A8I5ZK56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448800   ⟸   XM_017593311
- Peptide Label: isoform X3
- UniProtKB: A0JPJ0 (UniProtKB/TrEMBL),   E9PSK8 (UniProtKB/TrEMBL),   Q32WF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000041982   ⟸   ENSRNOT00000048914
RefSeq Acc Id: XP_038965628   ⟸   XM_039109700
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ANE3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965630   ⟸   XM_039109702
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038965632   ⟸   XM_039109704
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000097390   ⟸   ENSRNOT00000100229
RefSeq Acc Id: ENSRNOP00000083340   ⟸   ENSRNOT00000105546
RefSeq Acc Id: ENSRNOP00000076779   ⟸   ENSRNOT00000113614
Protein Domains
Cytidyltransferase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0JPJ0-F1-model_v2 AlphaFold A0JPJ0 1-285 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694272
Promoter ID:EPDNEW_R4797
Type:multiple initiation site
Name:Nmnat1_1
Description:nicotinamide nucleotide adenylyltransferase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05166,430,277 - 166,430,337EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310996 AgrOrtholog
BioCyc Gene G2FUF-39130 BioCyc
BioCyc Pathway PWY-5653 [NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde] BioCyc
  PWY3O-4107 [NAD salvage pathway V (PNC V cycle)] BioCyc
BioCyc Pathway Image PWY-5653 BioCyc
  PWY3O-4107 BioCyc
Ensembl Genes ENSRNOG00000015962 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048914 ENTREZGENE
  ENSRNOT00000048914.5 UniProtKB/TrEMBL
  ENSRNOT00000100229.1 UniProtKB/TrEMBL
  ENSRNOT00000105546.1 UniProtKB/TrEMBL
  ENSRNOT00000113614.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.620 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7383226 IMAGE-MGC_LOAD
InterPro Cyt_trans-like UniProtKB/TrEMBL
  NAMN_adtrnsfrase UniProtKB/TrEMBL
  NMNAT_euk UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
KEGG Report rno:298653 UniProtKB/TrEMBL
MGC_CLONE MGC:156478 IMAGE-MGC_LOAD
NCBI Gene 298653 ENTREZGENE
PANTHER NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE UniProtKB/TrEMBL
  NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 1 UniProtKB/TrEMBL
Pfam CTP_transf_2 UniProtKB/TrEMBL
PhenoGen Nmnat1 PhenoGen
RatGTEx ENSRNOG00000015962 RatGTEx
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/TrEMBL
UniProt A0A8I5ZK56 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZV91 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ANE3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8Y7I4_RAT UniProtKB/TrEMBL
  A0JPJ0 ENTREZGENE, UniProtKB/TrEMBL
  E9PSK8 ENTREZGENE
  Q32WF6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9PSK8 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Nmnat1  nicotinamide nucleotide adenylyltransferase 1  Nmnat1_predicted  nicotinamide nucleotide adenylyltransferase 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Nmnat1_predicted  nicotinamide nucleotide adenylyltransferase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED