Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DDX50 mRNA] | CTD | PMID:31150632 | (-)-demecolcine | increases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of DDX50 mRNA | CTD | PMID:23649840 | (1->4)-beta-D-glucan | multiple interactions | ISO | Ddx50 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of DDX50 mRNA | CTD | PMID:36331819 | 1,2-dichloroethane | decreases expression | ISO | Ddx50 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of DDX50 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | affects expression | ISO | Ddx50 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of DDX50 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Ddx50 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DDX50 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | Ddx50 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of DDX50 mRNA | CTD | PMID:17555576 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ddx50 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DDX50 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DDX50 mRNA | CTD | PMID:33387578 | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of DDX50 protein | CTD | PMID:34915118 | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of DDX50 mRNA | CTD | PMID:19162173 | 5-aza-2'-deoxycytidine | affects expression | ISO | DDX50 (Homo sapiens) | 6480464 | Decitabine affects the expression of DDX50 mRNA | CTD | PMID:23300844 | aflatoxin B1 | increases expression | ISO | Ddx50 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of DDX50 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DDX50 mRNA | CTD | PMID:33167477 | aripiprazole | increases expression | EXP | | 6480464 | Aripiprazole results in increased expression of DDX50 mRNA | CTD | PMID:17868501 | aristolochic acid A | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of DDX50 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases expression | ISO | Ddx50 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of DDX50 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases methylation | ISO | DDX50 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of DDX50 promoter | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | Ddx50 (Mus musculus) | 6480464 | bisphenol A results in increased expression of DDX50 mRNA | CTD | PMID:26063408 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DDX50 mRNA | CTD | PMID:34947998 | bisphenol A | decreases expression | ISO | Ddx50 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of DDX50 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DDX50 mRNA | CTD | PMID:25181051 | butanal | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of DDX50 mRNA | CTD | PMID:26079696 | CGP 52608 | multiple interactions | ISO | DDX50 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DDX50 gene] | CTD | PMID:28238834 | choline | multiple interactions | ISO | Ddx50 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DDX50 gene | CTD | PMID:20938992 | cisplatin | affects expression | ISO | DDX50 (Homo sapiens) | 6480464 | Cisplatin affects the expression of DDX50 mRNA | CTD | PMID:23300844 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of DDX50 mRNA | CTD | PMID:20187946 | coumarin | increases phosphorylation | ISO | DDX50 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of DDX50 protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DDX50 mRNA | CTD | PMID:20106945 and PMID:25562108 | dicrotophos | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of DDX50 mRNA | CTD | PMID:28302478 | doxorubicin | increases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of DDX50 mRNA | CTD | PMID:29803840 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of DDX50 mRNA | CTD | PMID:30307764 | folic acid | multiple interactions | ISO | Ddx50 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | formaldehyde | increases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of DDX50 mRNA | CTD | PMID:23649840 | FR900359 | affects phosphorylation | ISO | DDX50 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of DDX50 protein | CTD | PMID:37730182 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of DDX50 gene | CTD | PMID:22079235 | gallic acid | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Gallic Acid results in decreased expression of DDX50 mRNA | CTD | PMID:34408198 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of DDX50 mRNA | CTD | PMID:33387578 | hydrogen peroxide | affects expression | ISO | DDX50 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of DDX50 mRNA | CTD | PMID:20044591 | hydrogen peroxide | increases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of DDX50 mRNA | CTD | PMID:18951874 | ivermectin | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DDX50 protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | Ddx50 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DDX50 gene | CTD | PMID:20938992 | methyl methanesulfonate | increases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of DDX50 mRNA | CTD | PMID:23649840 | ochratoxin A | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | ochratoxin A results in decreased expression of DDX50 mRNA | CTD | PMID:29098329 | ochratoxin A | decreases acetylation | ISO | DDX50 (Homo sapiens) | 6480464 | ochratoxin A results in decreased acetylation of DDX50 promoter | CTD | PMID:29098329 | ochratoxin A | multiple interactions | ISO | DDX50 (Homo sapiens) | 6480464 | [ochratoxin A results in decreased acetylation of DDX50 promoter] which results in decreased expression of DDX50 mRNA | CTD | PMID:29098329 | perfluorononanoic acid | increases expression | ISO | DDX50 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of DDX50 mRNA | CTD | PMID:32588087 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ddx50 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of DDX50 mRNA | CTD | PMID:36331819 | raloxifene | affects expression | EXP | | 6480464 | Raloxifene Hydrochloride affects the expression of DDX50 mRNA | CTD | PMID:16079270 | resveratrol | decreases expression | ISO | Ddx50 (Mus musculus) | 6480464 | resveratrol results in decreased expression of DDX50 protein | CTD | PMID:25505154 | succimer | multiple interactions | ISO | Ddx50 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of DDX50 mRNA | CTD | PMID:21641980 | tamoxifen | affects expression | ISO | Ddx50 (Mus musculus) | 6480464 | Tamoxifen affects the expression of DDX50 mRNA | CTD | PMID:17555576 | tert-butyl hydroperoxide | decreases expression | ISO | Ddx50 (Mus musculus) | 6480464 | tert-Butylhydroperoxide results in decreased expression of DDX50 mRNA | CTD | PMID:15003993 | testosterone | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of DDX50 mRNA | CTD | PMID:33359661 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of DDX50 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DDX50 mRNA] | CTD | PMID:31150632 | tetrahydropalmatine | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | tetrahydropalmatine results in decreased expression of DDX50 protein | CTD | PMID:20109541 | trichostatin A | increases expression | ISO | DDX50 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of DDX50 mRNA | CTD | PMID:24935251 | valproic acid | decreases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DDX50 mRNA | CTD | PMID:23179753 | vincristine | increases expression | ISO | DDX50 (Homo sapiens) | 6480464 | Vincristine results in increased expression of DDX50 mRNA | CTD | PMID:23649840 | |