Saysd1 (SAYSVFN motif domain containing 1) - Rat Genome Database

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Gene: Saysd1 (SAYSVFN motif domain containing 1) Rattus norvegicus
Analyze
Symbol: Saysd1
Name: SAYSVFN motif domain containing 1
RGD ID: 1310877
Description: Orthologous to human SAYSD1 (SAYSVFN motif domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC305667; RGD1310877; SAYSvFN domain-containing protein 1; similar to RIKEN cDNA 1810063B07 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8154,273,302 - 4,278,971 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl154,273,012 - 4,278,971 (+)EnsemblGRCr8
mRatBN7.2154,224,129 - 4,229,798 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx154,234,544 - 4,240,213 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,620,973 - 5,626,642 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0154,233,368 - 4,239,037 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0154,657,680 - 4,663,863 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl154,658,246 - 4,663,694 (+)Ensemblrn6Rnor6.0
Rnor_5.0158,754,584 - 8,761,873 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4154,519,976 - 4,525,592 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera15371,869 - 378,115 (-)NCBICelera
RGSC_v3.1154,516,961 - 4,525,590 (+)NCBI
Cytogenetic Map15p16NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Saysd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8154,273,302 - 4,278,971 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl154,273,012 - 4,278,971 (+)EnsemblGRCr8
mRatBN7.2154,224,129 - 4,229,798 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx154,234,544 - 4,240,213 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,620,973 - 5,626,642 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0154,233,368 - 4,239,037 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0154,657,680 - 4,663,863 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl154,658,246 - 4,663,694 (+)Ensemblrn6Rnor6.0
Rnor_5.0158,754,584 - 8,761,873 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4154,519,976 - 4,525,592 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera15371,869 - 378,115 (-)NCBICelera
RGSC_v3.1154,516,961 - 4,525,590 (+)NCBI
Cytogenetic Map15p16NCBI
SAYSD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38639,104,063 - 39,115,186 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl639,104,063 - 39,115,193 (-)Ensemblhg38GRCh38
GRCh37639,071,839 - 39,082,962 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36639,179,818 - 39,190,843 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34639,179,817 - 39,190,843NCBI
Celera640,625,262 - 40,636,287 (-)NCBICelera
Cytogenetic Map6p21.2NCBI
HuRef638,790,270 - 38,801,295 (-)NCBIHuRef
CHM1_1639,074,536 - 39,085,558 (-)NCBICHM1_1
T2T-CHM13v2.0638,928,495 - 38,939,618 (-)NCBIT2T-CHM13v2.0
Saysd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391420,125,704 - 20,133,240 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1420,125,704 - 20,188,602 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381420,075,636 - 20,083,172 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1420,075,636 - 20,138,534 (-)Ensemblmm10GRCm38
MGSCv371420,894,858 - 20,902,394 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361418,866,332 - 18,873,981 (-)NCBIMGSCv36mm8
Celera1416,456,374 - 16,463,910 (-)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.4NCBI
Saysd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554374,369,141 - 4,375,968 (+)Ensembl
ChiLan1.0NW_0049554374,369,140 - 4,375,405 (+)NCBIChiLan1.0ChiLan1.0
SAYSD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2553,600,779 - 53,617,360 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1649,471,235 - 49,481,521 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0638,693,198 - 38,704,321 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1639,873,757 - 39,884,754 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl639,875,129 - 39,884,752 (-)EnsemblpanPan2panpan1.1
SAYSD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1128,044,811 - 8,051,239 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl128,045,069 - 8,051,148 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha128,068,383 - 8,074,884 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0128,522,664 - 8,529,053 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl128,522,922 - 8,528,973 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1128,049,806 - 8,056,389 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0128,127,399 - 8,133,775 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0128,232,892 - 8,239,478 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Saysd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494643,439,521 - 43,446,977 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647620,513,097 - 20,521,761 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647620,513,238 - 20,520,825 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SAYSD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl734,549,426 - 34,555,568 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1734,549,411 - 34,555,586 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SAYSD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11733,024,965 - 33,035,670 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1733,030,677 - 33,035,115 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604439,106,684 - 39,118,230 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Saysd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475419,190,151 - 19,195,470 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475419,190,157 - 19,195,995 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Saysd1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11289,882,162 - 89,887,833 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Saysd1
61 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:28
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000008391
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
1300142Bp191Blood pressure QTL 1913.14arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)15115177511Rat

Markers in Region
RH133548  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2154,229,564 - 4,229,764 (+)MAPPERmRatBN7.2
Rnor_6.0154,663,629 - 4,663,828NCBIRnor6.0
Rnor_5.0158,761,639 - 8,761,838UniSTSRnor5.0
RGSC_v3.4154,525,359 - 4,525,558UniSTSRGSC3.4
Celera15371,904 - 372,103UniSTS
RH 3.4 Map1568.8UniSTS
Cytogenetic Map15p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 91 59 6 355 191 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000008391   ⟹   ENSRNOP00000008391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl154,658,246 - 4,663,694 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172031   ⟹   ENSRNOP00000112287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl154,273,012 - 4,278,971 (+)Ensembl
RefSeq Acc Id: NM_001402359   ⟹   NP_001389288
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,273,302 - 4,278,971 (+)NCBI
mRatBN7.2154,224,129 - 4,229,798 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001389288 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL86209 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000112287.1
Ensembl Acc Id: ENSRNOP00000008391   ⟸   ENSRNOT00000008391
RefSeq Acc Id: NP_001389288   ⟸   NM_001402359
- UniProtKB: A6KKL5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000112287   ⟸   ENSRNOT00000172031
Protein Domains
SAYSvFN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQ21-F1-model_v2 AlphaFold D3ZQ21 1-188 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699571
Promoter ID:EPDNEW_R10094
Type:initiation region
Name:Saysd1_1
Description:SAYSvFN domain-containing protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0154,658,217 - 4,658,277EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310877 AgrOrtholog
BioCyc Gene G2FUF-14524 BioCyc
Ensembl Genes ENSRNOG00000006341 Ensembl
  ENSRNOG00000088418 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000172031.1 UniProtKB/TrEMBL
InterPro SAYSD1 UniProtKB/TrEMBL
  SAYSvFN_dom UniProtKB/TrEMBL
NCBI Gene 305667 ENTREZGENE
PANTHER SAYSVFN DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam SAYSvFN UniProtKB/TrEMBL
PhenoGen Saysd1 PhenoGen
RatGTEx ENSRNOG00000006341 RatGTEx
  ENSRNOG00000088418 RatGTEx
UniProt A0ABK0LMX8_RAT UniProtKB/TrEMBL
  A6KKL5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Saysd1  SAYSVFN motif domain containing 1  RGD1310877  similar to RIKEN cDNA 1810063B07 gene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1310877  similar to RIKEN cDNA 1810063B07 gene   RGD1310877_predicted  similar to RIKEN cDNA 1810063B07 gene (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1310877_predicted  similar to RIKEN cDNA 1810063B07 gene (predicted)  LOC305667_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC305667_predicted  similar to RIKEN cDNA 1810063B07 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL