Mllt10 (MLLT10, histone lysine methyltransferase DOT1L cofactor) - Rat Genome Database

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Pathways
Gene: Mllt10 (MLLT10, histone lysine methyltransferase DOT1L cofactor) Rattus norvegicus
Analyze
Symbol: Mllt10
Name: MLLT10, histone lysine methyltransferase DOT1L cofactor
RGD ID: 1310874
Description: Predicted to enable histone binding activity and nucleosome binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in acute monocytic leukemia and acute myeloid leukemia. Orthologous to human MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361285; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog (Drosophila); myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81785,729,964 - 85,857,791 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1785,730,751 - 85,857,789 (+)EnsemblGRCr8
mRatBN7.21780,821,870 - 80,949,349 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1780,822,556 - 80,949,345 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1784,294,521 - 84,421,795 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01788,129,933 - 88,257,195 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01782,153,817 - 82,279,445 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01784,847,660 - 84,981,134 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1784,881,414 - 84,979,543 (+)Ensemblrn6Rnor6.0
Rnor_5.01786,574,897 - 86,705,158 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41792,246,466 - 92,389,861 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1780,112,286 - 80,232,138 (+)NCBICelera
RGSC_v3.11792,257,298 - 92,400,692 (+)NCBI
Cytogenetic Map17q12.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
protein-containing complex  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene. Chaplin T, etal., Blood. 1995 Sep 15;86(6):2073-6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:15851025   PMID:17868029   PMID:26439302  


Genomics

Comparative Map Data
Mllt10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81785,729,964 - 85,857,791 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1785,730,751 - 85,857,789 (+)EnsemblGRCr8
mRatBN7.21780,821,870 - 80,949,349 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1780,822,556 - 80,949,345 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1784,294,521 - 84,421,795 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01788,129,933 - 88,257,195 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01782,153,817 - 82,279,445 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01784,847,660 - 84,981,134 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1784,881,414 - 84,979,543 (+)Ensemblrn6Rnor6.0
Rnor_5.01786,574,897 - 86,705,158 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41792,246,466 - 92,389,861 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1780,112,286 - 80,232,138 (+)NCBICelera
RGSC_v3.11792,257,298 - 92,400,692 (+)NCBI
Cytogenetic Map17q12.3NCBI
MLLT10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381021,533,756 - 21,743,630 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1021,524,617 - 21,743,630 (+)Ensemblhg38GRCh38
GRCh371021,822,685 - 22,032,559 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361021,863,108 - 22,072,560 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341021,863,107 - 22,072,560NCBI
Celera1021,495,732 - 21,720,297 (+)NCBICelera
Cytogenetic Map10p12.31NCBI
HuRef1021,476,633 - 21,694,284 (+)NCBIHuRef
CHM1_11021,823,893 - 22,033,408 (+)NCBICHM1_1
T2T-CHM13v2.01021,552,866 - 21,762,703 (+)NCBIT2T-CHM13v2.0
Mllt10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39218,059,971 - 18,217,201 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl218,060,048 - 18,217,199 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38218,055,160 - 18,212,390 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl218,055,237 - 18,212,388 (+)Ensemblmm10GRCm38
MGSCv37217,976,898 - 18,134,017 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36217,973,025 - 18,130,144 (+)NCBIMGSCv36mm8
Celera217,952,297 - 18,109,815 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map212.84NCBI
Mllt10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554296,999,333 - 7,163,990 (-)Ensembl
ChiLan1.0NW_0049554296,999,333 - 7,163,988 (-)NCBIChiLan1.0ChiLan1.0
MLLT10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2834,209,484 - 34,430,504 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11034,214,798 - 34,435,518 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01021,686,507 - 21,907,247 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11022,135,281 - 22,284,382 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1021,994,975 - 22,282,737 (+)EnsemblpanPan2panpan1.1
MLLT10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1211,349,864 - 11,607,194 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl211,349,856 - 11,596,398 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha210,042,564 - 10,291,025 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.029,598,648 - 9,848,677 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl29,597,996 - 9,847,891 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.128,911,703 - 9,160,725 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.028,996,500 - 9,245,212 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.029,172,316 - 9,421,340 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mllt10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934421,594,099 - 21,783,693 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365206,176,599 - 6,366,428 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365206,176,784 - 6,366,436 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MLLT10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1053,072,056 - 53,314,862 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11053,072,056 - 53,315,351 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21058,733,136 - 58,799,017 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Mllt10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247966,762,118 - 6,948,816 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247966,762,304 - 6,949,126 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mllt10
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1145,758,511 - 5,884,272 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mllt10
4167 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:214
Count of miRNA genes:137
Interacting mature miRNAs:175
Transcripts:ENSRNOT00000034157
Prediction methods:Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)177061350286062352Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)176456982086954580Rat

Markers in Region
D17Got112  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21780,910,934 - 80,911,129 (+)MAPPERmRatBN7.2
Rnor_6.01784,942,721 - 84,942,915NCBIRnor6.0
Rnor_5.01786,666,745 - 86,666,939UniSTSRnor5.0
RGSC_v3.41792,351,361 - 92,351,556RGDRGSC3.4
RGSC_v3.41792,351,362 - 92,351,556UniSTSRGSC3.4
Celera1780,193,576 - 80,193,770UniSTS
RGSC_v3.11792,362,195 - 92,362,389RGD
RH 3.4 Map17813.7UniSTS
RH 3.4 Map17813.7RGD
RH 2.0 Map17695.3RGD
Cytogenetic Map17q12.3UniSTS
D17Got113  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21780,910,523 - 80,910,635 (+)MAPPERmRatBN7.2
Rnor_6.01784,942,310 - 84,942,421NCBIRnor6.0
Rnor_5.01786,666,334 - 86,666,445UniSTSRnor5.0
RGSC_v3.41792,350,950 - 92,351,062RGDRGSC3.4
RGSC_v3.41792,350,951 - 92,351,062UniSTSRGSC3.4
Celera1780,193,165 - 80,193,276UniSTS
RGSC_v3.11792,361,783 - 92,361,895RGD
Cytogenetic Map17q12.3UniSTS
BE113290  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81785,846,493 - 85,847,036 (+)Marker Load Pipeline
mRatBN7.21780,938,051 - 80,938,594 (+)MAPPERmRatBN7.2
Rnor_6.01784,969,827 - 84,970,369NCBIRnor6.0
Rnor_5.01786,693,851 - 86,694,393UniSTSRnor5.0
RGSC_v3.41792,378,535 - 92,379,077UniSTSRGSC3.4
Celera1780,220,842 - 80,221,384UniSTS
RH 3.4 Map17829.4UniSTS
Cytogenetic Map17q12.3UniSTS
RH134595  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21780,948,837 - 80,948,992 (+)MAPPERmRatBN7.2
Rnor_6.01784,980,623 - 84,980,777NCBIRnor6.0
Rnor_5.01786,704,647 - 86,704,801UniSTSRnor5.0
RGSC_v3.41792,389,350 - 92,389,504UniSTSRGSC3.4
Celera1780,231,627 - 80,231,781UniSTS
RH 3.4 Map17830.1UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001443853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC087128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000034157   ⟹   ENSRNOP00000033877
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1780,853,490 - 80,945,922 (+)Ensembl
Rnor_6.0 Ensembl1784,881,414 - 84,979,543 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107584   ⟹   ENSRNOP00000093341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1785,731,644 - 85,857,788 (+)Ensembl
mRatBN7.2 Ensembl1780,822,556 - 80,949,345 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107857   ⟹   ENSRNOP00000077293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1785,731,212 - 85,857,788 (+)Ensembl
mRatBN7.2 Ensembl1780,822,556 - 80,949,345 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108200   ⟹   ENSRNOP00000081577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1785,730,751 - 85,857,789 (+)Ensembl
mRatBN7.2 Ensembl1780,822,771 - 80,945,922 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118456   ⟹   ENSRNOP00000078451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1785,731,644 - 85,857,788 (+)Ensembl
mRatBN7.2 Ensembl1780,823,192 - 80,949,345 (+)Ensembl
RefSeq Acc Id: NM_001012162   ⟹   NP_001012162
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,038 - 85,857,791 (+)NCBI
mRatBN7.21780,822,586 - 80,949,349 (+)NCBI
Rnor_6.01784,847,660 - 84,981,134 (+)NCBI
Rnor_5.01786,574,897 - 86,705,158 (+)NCBI
RGSC_v3.41792,246,466 - 92,389,861 (+)RGD
Celera1780,112,286 - 80,232,138 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095941   ⟹   XP_038951869
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,175 - 85,857,791 (+)NCBI
mRatBN7.21780,822,899 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095942   ⟹   XP_038951870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,857,791 (+)NCBI
mRatBN7.21780,822,536 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095943   ⟹   XP_038951871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,205 - 85,857,791 (+)NCBI
mRatBN7.21780,822,745 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095944   ⟹   XP_038951872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,203 - 85,857,791 (+)NCBI
mRatBN7.21780,822,745 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095945   ⟹   XP_038951873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,730,565 - 85,857,791 (+)NCBI
mRatBN7.21780,821,870 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095947   ⟹   XP_038951875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,175 - 85,857,791 (+)NCBI
mRatBN7.21780,822,899 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095948   ⟹   XP_038951876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,204 - 85,857,791 (+)NCBI
mRatBN7.21780,822,899 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095950   ⟹   XP_038951878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,848 - 85,857,791 (+)NCBI
mRatBN7.21780,823,395 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095952   ⟹   XP_038951880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,753,105 - 85,857,791 (+)NCBI
mRatBN7.21780,844,632 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095953   ⟹   XP_038951881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,753,605 - 85,857,791 (+)NCBI
mRatBN7.21780,823,228 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095955   ⟹   XP_038951883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,848 - 85,857,791 (+)NCBI
mRatBN7.21780,823,395 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095957   ⟹   XP_038951885
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,848 - 85,857,791 (+)NCBI
mRatBN7.21780,823,395 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095959   ⟹   XP_038951887
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,753,072 - 85,857,791 (+)NCBI
mRatBN7.21780,844,625 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_039095960   ⟹   XP_038951888
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,848 - 85,857,791 (+)NCBI
mRatBN7.21780,823,395 - 80,949,349 (+)NCBI
RefSeq Acc Id: XM_063276642   ⟹   XP_063132712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276643   ⟹   XP_063132713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276644   ⟹   XP_063132714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276646   ⟹   XP_063132716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,204 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276647   ⟹   XP_063132717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276648   ⟹   XP_063132718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276649   ⟹   XP_063132719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,204 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276650   ⟹   XP_063132720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,753,072 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276651   ⟹   XP_063132721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,848 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276652   ⟹   XP_063132722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276653   ⟹   XP_063132723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,848 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276654   ⟹   XP_063132724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276655   ⟹   XP_063132725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276656   ⟹   XP_063132726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,731,847 - 85,857,791 (+)NCBI
RefSeq Acc Id: XM_063276657   ⟹   XP_063132727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,847,050 (+)NCBI
RefSeq Acc Id: XM_063276658   ⟹   XP_063132728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81785,729,964 - 85,847,050 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001012162 (Get FASTA)   NCBI Sequence Viewer  
  NP_001430782 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951869 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951870 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951871 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951872 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951873 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951875 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951876 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951878 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951880 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951881 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951883 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951885 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951887 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951888 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132712 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132713 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132714 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132716 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132717 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132718 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132719 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132720 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132721 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132722 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132723 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132724 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132725 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132726 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132727 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132728 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87128 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000077293
  ENSRNOP00000077293.1
  ENSRNOP00000078451
  ENSRNOP00000078451.2
  ENSRNOP00000081577
  ENSRNOP00000081577.2
  ENSRNOP00000093341
  ENSRNOP00000093341.2
RefSeq Acc Id: NP_001012162   ⟸   NM_001012162
- Sequence:
Ensembl Acc Id: ENSRNOP00000033877   ⟸   ENSRNOT00000034157
RefSeq Acc Id: XP_038951873   ⟸   XM_039095945
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZKY6 (UniProtKB/TrEMBL),   A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951870   ⟸   XM_039095942
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951871   ⟸   XM_039095943
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZKY6 (UniProtKB/TrEMBL),   A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951872   ⟸   XM_039095944
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZKY6 (UniProtKB/TrEMBL),   A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951869   ⟸   XM_039095941
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZKY6 (UniProtKB/TrEMBL),   A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951875   ⟸   XM_039095947
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951876   ⟸   XM_039095948
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951881   ⟸   XM_039095953
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZK97 (UniProtKB/TrEMBL),   F1M8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951878   ⟸   XM_039095950
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZK97 (UniProtKB/TrEMBL),   F1M8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951885   ⟸   XM_039095957
- Peptide Label: isoform X14
- UniProtKB: F1M8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951883   ⟸   XM_039095955
- Peptide Label: isoform X13
- UniProtKB: A6JM89 (UniProtKB/TrEMBL),   F1M8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951888   ⟸   XM_039095960
- Peptide Label: isoform X17
- UniProtKB: F1M8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951887   ⟸   XM_039095959
- Peptide Label: isoform X14
- UniProtKB: F1M8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951880   ⟸   XM_039095952
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZK97 (UniProtKB/TrEMBL),   F1M8I4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078451   ⟸   ENSRNOT00000118456
Ensembl Acc Id: ENSRNOP00000077293   ⟸   ENSRNOT00000107857
Ensembl Acc Id: ENSRNOP00000093341   ⟸   ENSRNOT00000107584
Ensembl Acc Id: ENSRNOP00000081577   ⟸   ENSRNOT00000108200
RefSeq Acc Id: XP_063132712   ⟸   XM_063276642
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132724   ⟸   XM_063276654
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063132725   ⟸   XM_063276655
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063132713   ⟸   XM_063276643
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132717   ⟸   XM_063276647
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132718   ⟸   XM_063276648
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132714   ⟸   XM_063276644
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132722   ⟸   XM_063276652
- Peptide Label: isoform X12
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132727   ⟸   XM_063276657
- Peptide Label: isoform X19
RefSeq Acc Id: XP_063132728   ⟸   XM_063276658
- Peptide Label: isoform X20
RefSeq Acc Id: XP_063132716   ⟸   XM_063276646
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132719   ⟸   XM_063276649
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZT80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132726   ⟸   XM_063276656
- Peptide Label: isoform X18
- UniProtKB: F1M8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132721   ⟸   XM_063276651
- Peptide Label: isoform X11
- UniProtKB: A0A8I6GKM2 (UniProtKB/TrEMBL),   F1M8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132723   ⟸   XM_063276653
- Peptide Label: isoform X14
- UniProtKB: F1M8I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132720   ⟸   XM_063276650
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZK97 (UniProtKB/TrEMBL),   F1M8I4 (UniProtKB/TrEMBL)
Protein Domains
PHD-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M8I4-F1-model_v2 AlphaFold F1M8I4 1-978 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310874 AgrOrtholog
BioCyc Gene G2FUF-8569 BioCyc
Ensembl Genes ENSRNOG00000022249 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000107584 ENTREZGENE
  ENSRNOT00000107584.2 UniProtKB/TrEMBL
  ENSRNOT00000107857 ENTREZGENE
  ENSRNOT00000107857.2 UniProtKB/TrEMBL
  ENSRNOT00000108200 ENTREZGENE
  ENSRNOT00000108200.2 UniProtKB/TrEMBL
  ENSRNOT00000118456 ENTREZGENE
  ENSRNOT00000118456.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7112191 IMAGE-MGC_LOAD
InterPro AF10-like_CC UniProtKB/TrEMBL
  AF10/AF17_PHD UniProtKB/TrEMBL
  AF10_ePHD UniProtKB/TrEMBL
  EPHD UniProtKB/TrEMBL
  Histone_Mod_Regulator UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:361285 UniProtKB/TrEMBL
MGC_CLONE MGC:94916 IMAGE-MGC_LOAD
NCBI Gene 361285 ENTREZGENE
PANTHER PHD FINGER PROTEINS UniProtKB/TrEMBL
  PROTEIN AF-10 UniProtKB/TrEMBL
Pfam PHD_2 UniProtKB/TrEMBL
  zf-HC5HC2H UniProtKB/TrEMBL
  zf-HC5HC2H_2 UniProtKB/TrEMBL
PhenoGen Mllt10 PhenoGen
PROSITE EPHD UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022249 RatGTEx
SMART PHD UniProtKB/TrEMBL
Superfamily-SCOP SSF57903 UniProtKB/TrEMBL
UniProt A0A8I5ZK97 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZKY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZT80 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GKM2 ENTREZGENE, UniProtKB/TrEMBL
  A6JM89 ENTREZGENE, UniProtKB/TrEMBL
  F1M8I4 ENTREZGENE
  Q5PQL6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-18 Mllt10  MLLT10, histone lysine methyltransferase DOT1L cofactor  Mllt10  myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-01 Mllt10  myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10  Mllt10  myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-19 Mllt10  myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10  Mllt10  myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Mllt10  myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog (Drosophila)  Mllt10  myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Mllt10  myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10  Mllt10_predicted  myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Mllt10_predicted  myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (predicted)      Symbol and Name status set to approved 70820 APPROVED