Symbol:
Tchp
Name:
trichoplein, keratin filament binding
RGD ID:
1310813
Description:
Predicted to be involved in apoptotic process; negative regulation of cell growth; and negative regulation of cilium assembly. Predicted to be located in several cellular components, including apical cortex; centrosome; and desmosome. Predicted to be part of ciliary transition fiber. Predicted to be active in keratin filament. Orthologous to human TCHP (trichoplein keratin filament binding); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC304547; RGD1310813; similar to hypothetical protein MGC10854; trichoplein keratin filament-binding protein
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
TCHP (trichoplein keratin filament binding)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Tchp (trichoplein, keratin filament binding)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Tchp (trichoplein keratin filament binding)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
TCHP (trichoplein keratin filament binding)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
TCHP (trichoplein keratin filament binding)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Tchp (trichoplein keratin filament binding)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
TCHP (trichoplein keratin filament binding)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
TCHP (trichoplein keratin filament binding)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Tchp (trichoplein keratin filament binding)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Tchp (trichoplein keratin filament binding)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
MEDAG (mesenteric estrogen dependent adipogenesis)
HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Tchp (trichoplein, keratin filament binding)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
TCHP (trichoplein keratin filament binding)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
tchp (trichoplein, keratin filament binding)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
CG17230
Alliance
DIOPT (Hieranoid|OMA|PANTHER)
Drosophila melanogaster (fruit fly):
CG17230
Alliance
DIOPT (InParanoid|OMA|PANTHER)
Xenopus tropicalis (tropical clawed frog):
tchp
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
tchp
Alliance
DIOPT (OMA|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 12 47,538,520 - 47,553,895 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 12 47,538,520 - 47,553,836 (-) Ensembl GRCr8 mRatBN7.2 12 41,877,888 - 41,893,264 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 12 41,877,889 - 41,892,427 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 12 43,045,433 - 43,059,937 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 12 43,659,011 - 43,673,515 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 12 42,719,503 - 42,734,009 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 12 47,638,278 - 47,653,602 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 12 47,638,274 - 47,653,638 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 12 49,431,571 - 49,446,355 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 12 43,165,998 - 43,180,692 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 12 43,493,579 - 43,506,170 (-) NCBI Celera RGSC_v3.1 12 43,030,449 - 43,050,917 (-) NCBI Cytogenetic Map 12 q16 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Tchp Rat 1,1-dichloroethene increases expression ISO Tchp (Mus musculus) 6480464 vinylidene chloride results in increased expression of TCHP mRNA CTD PMID:26682919 Tchp Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Tchp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tchp Rat 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of TCHP mRNA CTD PMID:29097150 Tchp Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Tchp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tchp Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Tchp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tchp Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of TCHP mRNA CTD PMID:33387578 Tchp Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Tchp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tchp Rat 2,4-dinitrotoluene affects expression EXP 6480464 2,4-dinitrotoluene affects the expression of TCHP mRNA CTD PMID:21346803 Tchp Rat 2,6-dinitrotoluene affects expression EXP 6480464 2,6-dinitrotoluene affects the expression of TCHP mRNA CTD PMID:21346803 Tchp Rat 2-hydroxypropanoic acid decreases expression ISO TCHP (Homo sapiens) 6480464 Lactic Acid results in decreased expression of TCHP mRNA CTD PMID:30851411 Tchp Rat acrolein multiple interactions ISO TCHP (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... CTD PMID:32699268|PMID:32845096 Tchp Rat acrylamide decreases expression ISO TCHP (Homo sapiens) 6480464 Acrylamide results in decreased expression of TCHP mRNA CTD PMID:32763439 Tchp Rat aflatoxin B1 increases expression ISO Tchp (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of TCHP mRNA CTD PMID:19770486 Tchp Rat all-trans-retinoic acid decreases expression ISO TCHP (Homo sapiens) 6480464 Tretinoin results in decreased expression of TCHP mRNA CTD PMID:33167477 Tchp Rat alpha-pinene multiple interactions ISO TCHP (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... CTD PMID:32699268 Tchp Rat amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of TCHP mRNA CTD PMID:30779732 Tchp Rat aristolochic acid A decreases expression ISO TCHP (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of TCHP mRNA CTD PMID:33212167 Tchp Rat arsenite(3-) multiple interactions ISO TCHP (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to TCHP mRNA] CTD PMID:32406909 Tchp Rat atrazine decreases expression ISO TCHP (Homo sapiens) 6480464 Atrazine results in decreased expression of TCHP mRNA CTD PMID:22378314 Tchp Rat benzo[a]pyrene multiple interactions ISO Tchp (Mus musculus) 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of TCHP mRNA] CTD PMID:22228805 Tchp Rat benzo[a]pyrene decreases methylation ISO TCHP (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of TCHP promoter CTD PMID:27901495 Tchp Rat bis(2-ethylhexyl) phthalate increases expression ISO Tchp (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of TCHP mRNA CTD PMID:34319233 Tchp Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of TCHP mRNA CTD PMID:25181051 Tchp Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TCHP mRNA CTD PMID:30816183|PMID:32528016|PMID:34947998 Tchp Rat bisphenol F decreases expression ISO Tchp (Mus musculus) 6480464 bisphenol F results in decreased expression of TCHP mRNA CTD PMID:38685157 Tchp Rat cadmium atom multiple interactions ISO TCHP (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TCHP more ... CTD PMID:35301059 Tchp Rat cadmium atom multiple interactions ISO Tchp (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TCHP more ... CTD PMID:37236586 Tchp Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of TCHP mRNA CTD PMID:33453195 Tchp Rat cadmium dichloride multiple interactions ISO Tchp (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TCHP more ... CTD PMID:37236586 Tchp Rat cadmium dichloride multiple interactions ISO TCHP (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TCHP more ... CTD PMID:35301059 Tchp Rat caffeine decreases phosphorylation ISO TCHP (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of TCHP protein CTD PMID:35688186 Tchp Rat copper(II) sulfate decreases expression ISO TCHP (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of TCHP mRNA CTD PMID:19549813 Tchp Rat dextran sulfate increases expression ISO Tchp (Mus musculus) 6480464 Dextran Sulfate results in increased expression of TCHP mRNA CTD PMID:35093514 Tchp Rat leflunomide decreases expression ISO TCHP (Homo sapiens) 6480464 leflunomide results in decreased expression of TCHP mRNA CTD PMID:28988120 Tchp Rat methotrexate decreases expression ISO TCHP (Homo sapiens) 6480464 Methotrexate results in decreased expression of TCHP mRNA CTD PMID:24449571 Tchp Rat ozone multiple interactions ISO TCHP (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... CTD PMID:32699268|PMID:32845096 Tchp Rat PCB138 multiple interactions ISO Tchp (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tchp Rat perfluorohexanesulfonic acid decreases expression ISO TCHP (Homo sapiens) 6480464 perfluorohexanesulfonic acid results in decreased expression of TCHP mRNA CTD PMID:25812627 Tchp Rat perfluorononanoic acid decreases expression ISO TCHP (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of TCHP mRNA CTD PMID:25812627 Tchp Rat perfluorooctane-1-sulfonic acid decreases expression ISO TCHP (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of TCHP mRNA CTD PMID:25812627 Tchp Rat perfluorooctanoic acid decreases expression ISO TCHP (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of TCHP mRNA CTD PMID:25812627 Tchp Rat pirinixic acid multiple interactions ISO Tchp (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Tchp Rat rac-lactic acid decreases expression ISO TCHP (Homo sapiens) 6480464 Lactic Acid results in decreased expression of TCHP mRNA CTD PMID:30851411 Tchp Rat titanium dioxide increases expression ISO Tchp (Mus musculus) 6480464 titanium dioxide results in increased expression of TCHP mRNA CTD PMID:23131501 Tchp Rat titanium dioxide decreases methylation ISO Tchp (Mus musculus) 6480464 titanium dioxide results in decreased methylation of TCHP gene CTD PMID:35295148 Tchp Rat triphenyl phosphate affects expression ISO TCHP (Homo sapiens) 6480464 triphenyl phosphate affects the expression of TCHP mRNA CTD PMID:37042841 Tchp Rat valproic acid affects expression ISO TCHP (Homo sapiens) 6480464 Valproic Acid affects the expression of TCHP mRNA CTD PMID:25979313