Hsf4 (heat shock transcription factor 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Hsf4 (heat shock transcription factor 4) Rattus norvegicus
Analyze
Symbol: Hsf4
Name: heat shock transcription factor 4
RGD ID: 1310808
Description: Enables identical protein binding activity and sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription. Predicted to be located in chromatin. Human ortholog(s) of this gene implicated in cataract and cataract 5 multiple types. Orthologous to human HSF4 (heat shock transcription factor 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: heat shock factor protein 4; LOC291960
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,057,331 - 50,068,134 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1950,057,672 - 50,063,404 (+)EnsemblGRCr8
mRatBN7.21933,147,755 - 33,153,479 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,147,755 - 33,153,479 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1939,963,359 - 39,969,083 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,616,678 - 40,622,402 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01942,905,618 - 42,911,343 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,225,800 - 37,232,048 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,226,186 - 37,231,912 (+)Ensemblrn6Rnor6.0
Rnor_5.01948,091,442 - 48,097,634 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41935,085,532 - 35,091,256 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1932,576,531 - 32,582,255 (+)NCBICelera
RGSC_v3.11935,090,479 - 35,095,961 (+)NCBI
Cytogenetic Map19q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA,ISO)
nuclear speck  (IEA,ISO)
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Mutant DNA-binding domain of HSF4 is associated with autosomal dominant lamellar and Marner cataract. Bu L, etal., Nat Genet. 2002 Jul;31(3):276-8. Epub 2002 Jun 24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KLF6 and HSF4 transcriptionally regulate multidrug resistance transporters during inflammation. Ho EA and Piquette-Miller M, Biochem Biophys Res Commun. 2007 Feb 16;353(3):679-85. Epub 2006 Dec 20.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Developmentally dictated expression of heat shock factors: exclusive expression of HSF4 in the postnatal lens and its specific interaction with alphaB-crystallin heat shock promoter. Somasundaram T and Bhat SP, J Biol Chem. 2004 Oct 22;279(43):44497-503. Epub 2004 Aug 12.
Additional References at PubMed
PMID:15343150   PMID:15483628   PMID:15593327   PMID:16581800   PMID:16595169   PMID:18755693  


Genomics

Comparative Map Data
Hsf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,057,331 - 50,068,134 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1950,057,672 - 50,063,404 (+)EnsemblGRCr8
mRatBN7.21933,147,755 - 33,153,479 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,147,755 - 33,153,479 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1939,963,359 - 39,969,083 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,616,678 - 40,622,402 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01942,905,618 - 42,911,343 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,225,800 - 37,232,048 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,226,186 - 37,231,912 (+)Ensemblrn6Rnor6.0
Rnor_5.01948,091,442 - 48,097,634 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41935,085,532 - 35,091,256 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1932,576,531 - 32,582,255 (+)NCBICelera
RGSC_v3.11935,090,479 - 35,095,961 (+)NCBI
Cytogenetic Map19q11NCBI
HSF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,163,761 - 67,169,941 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,164,681 - 67,169,945 (+)Ensemblhg38GRCh38
GRCh371667,197,664 - 67,203,844 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,754,858 - 65,761,349 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341665,756,216 - 65,761,347NCBI
Celera1651,705,531 - 51,712,092 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,070,801 - 53,077,037 (+)NCBIHuRef
CHM1_11668,604,606 - 68,611,167 (+)NCBICHM1_1
T2T-CHM13v2.01672,958,053 - 72,964,234 (+)NCBIT2T-CHM13v2.0
Hsf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398105,996,392 - 106,002,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8105,996,433 - 106,002,477 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388105,269,414 - 105,275,845 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,269,801 - 105,275,845 (+)Ensemblmm10GRCm38
MGSCv378107,793,774 - 107,799,745 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368108,159,003 - 108,164,974 (+)NCBIMGSCv36mm8
Celera8109,493,023 - 109,498,994 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Hsf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,447,641 - 9,452,784 (-)Ensembl
ChiLan1.0NW_0049554849,447,641 - 9,452,784 (-)NCBIChiLan1.0ChiLan1.0
HSF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21876,694,551 - 76,700,125 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11682,607,116 - 82,612,698 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01647,509,458 - 47,516,060 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11666,897,868 - 66,904,640 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1666,897,868 - 66,904,179 (+)EnsemblpanPan2panpan1.1
Hsf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,945,328 - 41,950,179 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647517,638,971 - 17,643,786 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647517,638,785 - 17,643,786 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100523672
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,808,652 - 27,818,750 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1627,808,658 - 27,818,256 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2625,078,845 - 25,088,372 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1560,286,882 - 60,292,974 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl560,287,040 - 60,292,499 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604723,039,075 - 23,044,939 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsf4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11724,996,938 - 25,002,777 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hsf4
36 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:90
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000065013
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat

Markers in Region
RH134529  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21933,147,037 - 33,147,225 (+)MAPPERmRatBN7.2
Rnor_6.01937,225,471 - 37,225,658NCBIRnor6.0
Rnor_5.01948,091,193 - 48,091,380UniSTSRnor5.0
RGSC_v3.41935,084,815 - 35,085,002UniSTSRGSC3.4
Celera1932,575,814 - 32,576,001UniSTS
RH 3.4 Map19360.41UniSTS
Cytogenetic Map19q11UniSTS
BF409761  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21933,153,250 - 33,153,462 (+)MAPPERmRatBN7.2
Rnor_6.01937,231,684 - 37,231,895NCBIRnor6.0
Rnor_5.01948,097,406 - 48,097,617UniSTSRnor5.0
RGSC_v3.41935,091,028 - 35,091,239UniSTSRGSC3.4
Celera1932,582,027 - 32,582,238UniSTS
RH 3.4 Map19362.81UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
19 13 73 190 89 88 57 105 57 6 396 221 21 165 91 124 31 31 31

Sequence


Ensembl Acc Id: ENSRNOT00000065013   ⟹   ENSRNOP00000061491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1950,057,680 - 50,063,404 (+)Ensembl
mRatBN7.2 Ensembl1933,147,755 - 33,153,479 (+)Ensembl
Rnor_6.0 Ensembl1937,226,188 - 37,231,912 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000075933   ⟹   ENSRNOP00000068369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1950,057,672 - 50,063,404 (+)Ensembl
mRatBN7.2 Ensembl1933,147,756 - 33,153,472 (+)Ensembl
Rnor_6.0 Ensembl1937,226,186 - 37,231,912 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076335   ⟹   ENSRNOP00000068274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1950,057,672 - 50,063,404 (+)Ensembl
mRatBN7.2 Ensembl1933,147,798 - 33,153,479 (+)Ensembl
Rnor_6.0 Ensembl1937,229,120 - 37,231,615 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118285   ⟹   ENSRNOP00000094806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1950,057,672 - 50,063,404 (+)Ensembl
mRatBN7.2 Ensembl1933,147,756 - 33,153,472 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000165455   ⟹   ENSRNOP00000099461
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1950,057,672 - 50,063,400 (+)Ensembl
RefSeq Acc Id: NM_001106177   ⟹   NP_001099647
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,057,680 - 50,063,404 (+)NCBI
mRatBN7.21933,147,755 - 33,153,479 (+)NCBI
Rnor_6.01937,226,188 - 37,231,912 (+)NCBI
Rnor_5.01948,091,442 - 48,097,634 (+)NCBI
RGSC_v3.41935,085,532 - 35,091,256 (+)RGD
Celera1932,576,531 - 32,582,255 (+)RGD
Sequence:
RefSeq Acc Id: XM_063277903   ⟹   XP_063133973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,057,331 - 50,063,404 (+)NCBI
RefSeq Acc Id: XM_063277904   ⟹   XP_063133974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,057,331 - 50,068,134 (+)NCBI
RefSeq Acc Id: XM_063277905   ⟹   XP_063133975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,057,331 - 50,068,134 (+)NCBI
RefSeq Acc Id: XM_063277906   ⟹   XP_063133976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,057,331 - 50,062,371 (+)NCBI
RefSeq Acc Id: XM_063277907   ⟹   XP_063133977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,057,331 - 50,060,695 (+)NCBI
RefSeq Acc Id: XM_063277908   ⟹   XP_063133978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,057,331 - 50,062,371 (+)NCBI
RefSeq Acc Id: NP_001099647   ⟸   NM_001106177
- UniProtKB: D4A5A8 (UniProtKB/TrEMBL),   A6IYM9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061491   ⟸   ENSRNOT00000065013
Ensembl Acc Id: ENSRNOP00000068369   ⟸   ENSRNOT00000075933
Ensembl Acc Id: ENSRNOP00000068274   ⟸   ENSRNOT00000076335
Ensembl Acc Id: ENSRNOP00000094806   ⟸   ENSRNOT00000118285
RefSeq Acc Id: XP_063133974   ⟸   XM_063277904
- Peptide Label: isoform X2
- UniProtKB: A6IYM7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133975   ⟸   XM_063277905
- Peptide Label: isoform X3
- UniProtKB: A6IYM7 (UniProtKB/TrEMBL),   A0A096MK39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133973   ⟸   XM_063277903
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AKB5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133976   ⟸   XM_063277906
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063133978   ⟸   XM_063277908
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063133977   ⟸   XM_063277907
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000099461   ⟸   ENSRNOT00000165455
Protein Domains
HSF-type DNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MK39-F1-model_v2 AlphaFold A0A096MK39 1-489 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701069
Promoter ID:EPDNEW_R11592
Type:initiation region
Name:Hsf4_1
Description:heat shock transcription factor 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01937,226,231 - 37,226,291EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310808 AgrOrtholog
BioCyc Gene G2FUF-5848 BioCyc
Ensembl Genes ENSRNOG00000015253 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000065013 ENTREZGENE
  ENSRNOT00000065013.4 UniProtKB/TrEMBL
  ENSRNOT00000075933 ENTREZGENE
  ENSRNOT00000075933.4 UniProtKB/TrEMBL
  ENSRNOT00000076335.3 UniProtKB/TrEMBL
  ENSRNOT00000118285.2 UniProtKB/TrEMBL
  ENSRNOT00000165455 ENTREZGENE
  ENSRNOT00000165455.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro HSF_DNA-bd UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:291960 UniProtKB/TrEMBL
NCBI Gene 291960 ENTREZGENE
PANTHER HEAT SHOCK FACTOR PROTEIN 4 UniProtKB/TrEMBL
  PTHR10015 UniProtKB/TrEMBL
Pfam HSF_DNA-bind UniProtKB/TrEMBL
PhenoGen Hsf4 PhenoGen
PRINTS HSFDOMAIN UniProtKB/TrEMBL
PROSITE HSF_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015253 RatGTEx
SMART HSF UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A096MJV3_RAT UniProtKB/TrEMBL
  A0A096MK39 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AKB5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0KXJ2_RAT UniProtKB/TrEMBL
  A6IYM7 ENTREZGENE, UniProtKB/TrEMBL
  A6IYM9 ENTREZGENE, UniProtKB/TrEMBL
  D4A5A8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Hsf4  heat shock transcription factor 4   Hsf4_predicted  heat shock transcription factor 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Hsf4_predicted  heat shock transcription factor 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED