Lingo2 (leucine rich repeat and Ig domain containing 2) - Rat Genome Database

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Pathways
Gene: Lingo2 (leucine rich repeat and Ig domain containing 2) Rattus norvegicus
Analyze
Symbol: Lingo2
Name: leucine rich repeat and Ig domain containing 2
RGD ID: 1310773
Description: Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in synaptic membrane adhesion. Predicted to act upstream of or within positive regulation of synapse assembly. Is active in glutamatergic synapse and synaptic membrane. Orthologous to human LINGO2 (leucine rich repeat and Ig domain containing 2); INTERACTS WITH bisphenol A; cadmium dichloride; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC313156; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; LOC313156; RGD1310773; similar to hypothetical protein FLJ31810; uncharacterized protein LOC313156
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8555,166,250 - 56,488,672 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl555,156,997 - 56,489,155 (-)EnsemblGRCr8
mRatBN7.2550,370,744 - 51,687,252 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl550,367,101 - 50,516,956 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx552,565,927 - 52,708,396 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0554,163,406 - 54,305,883 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0554,065,306 - 54,207,789 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0551,466,367 - 51,638,161 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0556,027,971 - 56,198,552 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4552,476,741 - 52,590,042 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera549,086,900 - 49,231,177 (-)NCBICelera
Cytogenetic Map5q21-q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Loh KH, etal., Cell. 2016 Aug 25;166(5):1295-1307.e21. doi: 10.1016/j.cell.2016.07.041.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:24613359  


Genomics

Comparative Map Data
Lingo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8555,166,250 - 56,488,672 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl555,156,997 - 56,489,155 (-)EnsemblGRCr8
mRatBN7.2550,370,744 - 51,687,252 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl550,367,101 - 50,516,956 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx552,565,927 - 52,708,396 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0554,163,406 - 54,305,883 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0554,065,306 - 54,207,789 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0551,466,367 - 51,638,161 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0556,027,971 - 56,198,552 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4552,476,741 - 52,590,042 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera549,086,900 - 49,231,177 (-)NCBICelera
Cytogenetic Map5q21-q22NCBI
LINGO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38927,937,617 - 29,213,601 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl927,937,617 - 29,213,601 (-)Ensemblhg38GRCh38
GRCh37927,937,615 - 29,213,599 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36927,938,528 - 28,709,303 (-)NCBIBuild 36Build 36hg18NCBI36
Celera927,876,621 - 28,649,863 (-)NCBICelera
Cytogenetic Map9p21.2-p21.1NCBI
HuRef927,900,694 - 29,165,921 (-)NCBIHuRef
CHM1_1927,947,856 - 29,212,826 (-)NCBICHM1_1
T2T-CHM13v2.0927,948,210 - 29,231,596 (-)NCBIT2T-CHM13v2.0
Lingo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39435,696,778 - 36,951,929 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl435,706,647 - 36,951,747 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38435,696,778 - 36,951,744 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl435,706,647 - 36,951,747 (-)Ensemblmm10GRCm38
MGSCv37435,653,896 - 36,898,777 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36435,896,291 - 36,034,083 (-)NCBIMGSCv36mm8
Celera435,399,009 - 36,648,653 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map417.74NCBI
Lingo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554726,968,576 - 6,970,396 (+)Ensembl
ChiLan1.0NW_0049554725,790,522 - 6,971,152 (+)NCBIChiLan1.0ChiLan1.0
LINGO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21195,382,085 - 96,628,142 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1995,388,029 - 96,634,088 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0927,760,276 - 29,008,800 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1928,366,227 - 29,779,879 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl928,377,472 - 28,379,292 (-)EnsemblpanPan2panpan1.1
LINGO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11145,997,900 - 47,115,857 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1145,998,249 - 46,000,069 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1144,665,908 - 45,803,522 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01146,943,920 - 48,068,400 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1146,944,491 - 46,946,845 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11145,599,200 - 46,722,220 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01145,496,756 - 46,618,731 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01146,237,174 - 47,354,240 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lingo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947160,911,991 - 161,400,764 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366111,747,626 - 1,749,446 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366111,267,679 - 1,434,908 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LINGO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1038,026,962 - 38,028,782 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11036,741,209 - 38,031,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LINGO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1252,120,442 - 52,122,262 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Lingo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473632,186,995 - 32,203,250 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473632,177,085 - 33,454,296 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lingo2
(Rattus rattus - black rat)
No map positions available.

Variants

.
Variants in Lingo2
10461 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:127
Count of miRNA genes:86
Interacting mature miRNAs:111
Transcripts:ENSRNOT00000007449
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
D5Rat6  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8555,251,577 - 55,251,722 (+)Marker Load Pipeline
mRatBN7.2550,455,368 - 50,455,513 (+)MAPPERmRatBN7.2
Rnor_6.0551,578,827 - 51,578,971NCBIRnor6.0
Rnor_5.0556,139,218 - 56,139,362UniSTSRnor5.0
RGSC_v3.4552,530,469 - 52,530,898RGDRGSC3.4
RGSC_v3.4552,530,708 - 52,530,852UniSTSRGSC3.4
Celera549,170,468 - 49,170,612UniSTS
RGSC_v3.1552,530,887 - 52,531,031RGD
RH 3.4 Map5308.6UniSTS
RH 3.4 Map5308.6RGD
RH 2.0 Map5350.2RGD
SHRSP x BN Map533.9799RGD
FHH x ACI Map530.19RGD
Cytogenetic Map5q22UniSTS
Lingo2  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4552,478,584 - 52,479,220UniSTSRGSC3.4
Celera549,088,743 - 49,089,378UniSTS
Cytogenetic Map5q22UniSTS
Lingo2  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4552,478,323 - 52,479,100UniSTSRGSC3.4
Celera549,088,482 - 49,089,258UniSTS
Cytogenetic Map5q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
3 7 33 33 63 43 4 30 17 25 16 16

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010066382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010066383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000007449   ⟹   ENSRNOP00000065270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl550,371,483 - 50,514,709 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104376   ⟹   ENSRNOP00000097289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,159,738 - 56,488,854 (-)Ensembl
mRatBN7.2 Ensembl550,367,101 - 50,515,653 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110514   ⟹   ENSRNOP00000096450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,162,704 - 56,489,155 (-)Ensembl
mRatBN7.2 Ensembl550,367,836 - 50,514,915 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114077   ⟹   ENSRNOP00000093394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,157,195 - 55,316,461 (-)Ensembl
mRatBN7.2 Ensembl550,367,404 - 50,396,482 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119962   ⟹   ENSRNOP00000081619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,162,445 - 56,489,155 (-)Ensembl
mRatBN7.2 Ensembl550,367,404 - 50,516,956 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000124988   ⟹   ENSRNOP00000102682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,156,997 - 56,489,155 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133706   ⟹   ENSRNOP00000107874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,159,741 - 56,489,155 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000150114   ⟹   ENSRNOP00000111166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,166,173 - 56,489,155 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155033   ⟹   ENSRNOP00000110081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,156,997 - 56,489,155 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000170838   ⟹   ENSRNOP00000112761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,157,204 - 56,489,155 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000172995   ⟹   ENSRNOP00000112259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl555,157,250 - 56,489,155 (-)Ensembl
RefSeq Acc Id: NM_001107926   ⟹   NP_001101396
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,167,693 - 55,310,912 (-)NCBI
mRatBN7.2550,371,483 - 50,514,709 (-)NCBI
Rnor_6.0551,466,367 - 51,638,161 (-)NCBI
Rnor_5.0556,027,971 - 56,198,552 (-)NCBI
RGSC_v3.4552,476,741 - 52,590,042 (-)RGD
Celera549,086,900 - 49,231,177 (-)RGD
Sequence:
RefSeq Acc Id: XM_039109831   ⟹   XP_038965759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 56,488,672 (-)NCBI
mRatBN7.2550,370,744 - 51,685,656 (-)NCBI
RefSeq Acc Id: XM_039109832   ⟹   XP_038965760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 56,488,672 (-)NCBI
mRatBN7.2550,370,744 - 51,685,656 (-)NCBI
RefSeq Acc Id: XM_063287591   ⟹   XP_063143661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 56,488,672 (-)NCBI
RefSeq Acc Id: XM_063287592   ⟹   XP_063143662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 56,488,672 (-)NCBI
RefSeq Acc Id: XM_063287593   ⟹   XP_063143663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 56,488,672 (-)NCBI
RefSeq Acc Id: XM_063287594   ⟹   XP_063143664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 56,488,672 (-)NCBI
RefSeq Acc Id: XM_063287595   ⟹   XP_063143665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 56,481,164 (-)NCBI
RefSeq Acc Id: XM_063287596   ⟹   XP_063143666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 56,488,672 (-)NCBI
RefSeq Acc Id: XM_063287597   ⟹   XP_063143667
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 55,998,881 (-)NCBI
RefSeq Acc Id: XM_063287598   ⟹   XP_063143668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 55,998,881 (-)NCBI
RefSeq Acc Id: XM_063287599   ⟹   XP_063143669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,166,250 - 55,317,518 (-)NCBI
RefSeq Acc Id: XR_010066382
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,622,048 - 56,488,672 (-)NCBI
RefSeq Acc Id: XR_010066383
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8555,342,230 - 56,488,672 (-)NCBI
RefSeq Acc Id: NP_001101396   ⟸   NM_001107926
- Peptide Label: precursor
- UniProtKB: M0R752 (UniProtKB/TrEMBL),   A6IIP9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038965760   ⟸   XM_039109832
- Peptide Label: isoform X1
- UniProtKB: M0R752 (UniProtKB/TrEMBL),   A6IIP9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965759   ⟸   XM_039109831
- Peptide Label: isoform X1
- UniProtKB: M0R752 (UniProtKB/TrEMBL),   A6IIP9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000097289   ⟸   ENSRNOT00000104376
Ensembl Acc Id: ENSRNOP00000065270   ⟸   ENSRNOT00000007449
Ensembl Acc Id: ENSRNOP00000096450   ⟸   ENSRNOT00000110514
Ensembl Acc Id: ENSRNOP00000081619   ⟸   ENSRNOT00000119962
Ensembl Acc Id: ENSRNOP00000093394   ⟸   ENSRNOT00000114077
RefSeq Acc Id: XP_063143666   ⟸   XM_063287596
- Peptide Label: isoform X1
- UniProtKB: A6IIP9 (UniProtKB/TrEMBL),   M0R752 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143664   ⟸   XM_063287594
- Peptide Label: isoform X1
- UniProtKB: A6IIP9 (UniProtKB/TrEMBL),   M0R752 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143661   ⟸   XM_063287591
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063143662   ⟸   XM_063287592
- Peptide Label: isoform X1
- UniProtKB: A6IIP9 (UniProtKB/TrEMBL),   M0R752 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143663   ⟸   XM_063287593
- Peptide Label: isoform X1
- UniProtKB: A6IIP9 (UniProtKB/TrEMBL),   M0R752 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143665   ⟸   XM_063287595
- Peptide Label: isoform X1
- UniProtKB: A6IIP9 (UniProtKB/TrEMBL),   M0R752 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143668   ⟸   XM_063287598
- Peptide Label: isoform X1
- UniProtKB: A6IIP9 (UniProtKB/TrEMBL),   M0R752 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143667   ⟸   XM_063287597
- Peptide Label: isoform X1
- UniProtKB: A6IIP9 (UniProtKB/TrEMBL),   M0R752 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143669   ⟸   XM_063287599
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000112259   ⟸   ENSRNOT00000172995
Ensembl Acc Id: ENSRNOP00000107874   ⟸   ENSRNOT00000133706
Ensembl Acc Id: ENSRNOP00000110081   ⟸   ENSRNOT00000155033
Ensembl Acc Id: ENSRNOP00000112761   ⟸   ENSRNOT00000170838
Ensembl Acc Id: ENSRNOP00000111166   ⟸   ENSRNOT00000150114
Ensembl Acc Id: ENSRNOP00000102682   ⟸   ENSRNOT00000124988
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R752-F1-model_v2 AlphaFold M0R752 1-425 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310773 AgrOrtholog
BioCyc Gene G2FUF-41630 BioCyc
Ensembl Genes ENSRNOG00000005634 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000104376 ENTREZGENE
  ENSRNOT00000104376.2 UniProtKB/TrEMBL
  ENSRNOT00000110514.2 UniProtKB/TrEMBL
  ENSRNOT00000114077 ENTREZGENE
  ENSRNOT00000114077.2 UniProtKB/TrEMBL
  ENSRNOT00000119962 ENTREZGENE
  ENSRNOT00000119962.2 UniProtKB/TrEMBL
  ENSRNOT00000124988 ENTREZGENE
  ENSRNOT00000124988.1 UniProtKB/TrEMBL
  ENSRNOT00000133706.1 UniProtKB/TrEMBL
  ENSRNOT00000150114.1 UniProtKB/TrEMBL
  ENSRNOT00000155033 ENTREZGENE
  ENSRNOT00000155033.1 UniProtKB/TrEMBL
  ENSRNOT00000170838 ENTREZGENE
  ENSRNOT00000170838.1 UniProtKB/TrEMBL
  ENSRNOT00000172995 ENTREZGENE
  ENSRNOT00000172995.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRR_TM_domain-containing UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
KEGG Report rno:313156 UniProtKB/TrEMBL
NCBI Gene 313156 ENTREZGENE
PANTHER ANTIGEN BSP, PUTATIVE-RELATED UniProtKB/TrEMBL
  LEUCINE RICH REPEAT AND IG DOMAIN CONTAINING 2 UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PhenoGen Lingo2 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005634 RatGTEx
SMART IGc2 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A6IIP9 ENTREZGENE, UniProtKB/TrEMBL
  M0R752 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Lingo2  leucine rich repeat and Ig domain containing 2  RGD1310773  similar to hypothetical protein FLJ31810  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1310773  similar to hypothetical protein FLJ31810   RGD1310773_predicted  similar to hypothetical protein FLJ31810 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1310773_predicted  similar to hypothetical protein FLJ31810 (predicted)  LOC313156_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313156_predicted  similar to hypothetical protein FLJ31810 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL