Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cachd1 | Rat | 1,1-dichloroethene | decreases expression | ISO | Cachd1 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of CACHD1 mRNA | CTD | PMID:26682919 | Cachd1 | Rat | 1,2-dichloroethane | decreases expression | ISO | Cachd1 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of CACHD1 mRNA | CTD | PMID:28960355 | Cachd1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Cachd1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CACHD1 mRNA | CTD | PMID:22206623 | Cachd1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Cachd1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of CACHD1 mRNA | CTD | PMID:22206623 | Cachd1 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Cachd1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of CACHD1 mRNA | CTD | PMID:17555576 | Cachd1 | Rat | 17beta-estradiol | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | EGF protein inhibits the reaction [Estradiol results in decreased expression of CACHD1 mRNA] | CTD | PMID:24758408 | Cachd1 | Rat | 17beta-estradiol | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of CACHD1 mRNA | CTD | PMID:24758408 | Cachd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Cachd1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CACHD1 mRNA | CTD | PMID:19770486 | Cachd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CACHD1 mRNA | CTD | PMID:33387578 | Cachd1 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Cachd1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of CACHD1 mRNA | CTD | PMID:28973697 | Cachd1 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of CACHD1 mRNA | CTD | PMID:31881176 | Cachd1 | Rat | aflatoxin B1 | decreases expression | ISO | Cachd1 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of CACHD1 mRNA | CTD | PMID:19770486 | Cachd1 | Rat | aflatoxin B1 | increases methylation | ISO | CACHD1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of CACHD1 promoter | CTD | PMID:30157460 | Cachd1 | Rat | aristolochic acid A | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of CACHD1 mRNA | CTD | PMID:33212167 | Cachd1 | Rat | arsenite(3-) | decreases methylation | ISO | CACHD1 (Homo sapiens) | 6480464 | arsenite results in decreased methylation of CACHD1 promoter | CTD | PMID:23974009 | Cachd1 | Rat | benzo[a]pyrene | increases expression | ISO | Cachd1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of CACHD1 mRNA | CTD | PMID:19770486|PMID:32417428 | Cachd1 | Rat | benzo[a]pyrene | increases methylation | ISO | CACHD1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CACHD1 3' UTR; Benzo(a)pyrene results in increased methylation of more ... | CTD | PMID:27901495 | Cachd1 | Rat | benzo[e]pyrene | increases methylation | ISO | CACHD1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of CACHD1 promoter | CTD | PMID:30157460 | Cachd1 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of CACHD1 mRNA | CTD | PMID:31163220 | Cachd1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CACHD1 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:34947998 | Cachd1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CACHD1 mRNA | CTD | PMID:41034487 | Cachd1 | Rat | bisphenol A | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CACHD1 gene | CTD | PMID:31601247 | Cachd1 | Rat | Butylbenzyl phthalate | decreases expression | ISO | Cachd1 (Mus musculus) | 6480464 | butylbenzyl phthalate results in decreased expression of CACHD1 mRNA | CTD | PMID:28392331 | Cachd1 | Rat | C60 fullerene | affects expression | EXP | | 6480464 | fullerene C60 affects the expression of CACHD1 mRNA | CTD | PMID:19167457 | Cachd1 | Rat | cadmium dichloride | increases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of CACHD1 mRNA | CTD | PMID:38382870 | Cachd1 | Rat | carbamazepine | affects expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of CACHD1 mRNA | CTD | PMID:25979313 | Cachd1 | Rat | CGP 52608 | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CACHD1 gene] | CTD | PMID:28238834 | Cachd1 | Rat | cisplatin | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of CACHD1 mRNA | CTD | PMID:27392435 | Cachd1 | Rat | cisplatin | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of CACHD1 mRNA | CTD | PMID:27392435 | Cachd1 | Rat | copper atom | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of CACHD1 mRNA | CTD | PMID:20971185 | Cachd1 | Rat | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of CACHD1 mRNA | CTD | PMID:30556269 | Cachd1 | Rat | copper(0) | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of CACHD1 mRNA | CTD | PMID:20971185 | Cachd1 | Rat | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of CACHD1 mRNA | CTD | PMID:30556269 | Cachd1 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of CACHD1 mRNA | CTD | PMID:26577399 | Cachd1 | Rat | cyclosporin A | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of CACHD1 mRNA | CTD | PMID:20106945|PMID:27989131 | Cachd1 | Rat | cyclosporin A | increases expression | ISO | Cachd1 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of CACHD1 mRNA | CTD | PMID:19770486 | Cachd1 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of CACHD1 mRNA | CTD | PMID:23914054 | Cachd1 | Rat | dorsomorphin | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Cachd1 | Rat | doxorubicin | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of CACHD1 mRNA | CTD | PMID:29803840 | Cachd1 | Rat | epoxiconazole | increases expression | ISO | Cachd1 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of CACHD1 mRNA | CTD | PMID:35436446 | Cachd1 | Rat | ethanol | increases expression | ISO | Cachd1 (Mus musculus) | 6480464 | Ethanol results in increased expression of CACHD1 mRNA | CTD | PMID:30319688 | Cachd1 | Rat | folic acid | multiple interactions | ISO | Cachd1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CACHD1 mRNA | CTD | PMID:22206623 | Cachd1 | Rat | fulvestrant | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CACHD1 gene | CTD | PMID:31601247 | Cachd1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of CACHD1 mRNA | CTD | PMID:33387578 | Cachd1 | Rat | inulin | multiple interactions | ISO | Cachd1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CACHD1 mRNA | CTD | PMID:36331819 | Cachd1 | Rat | lead(0) | affects splicing | ISO | CACHD1 (Homo sapiens) | 6480464 | Lead affects the splicing of CACHD1 mRNA | CTD | PMID:28903495 | Cachd1 | Rat | lipopolysaccharide | increases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of CACHD1 mRNA | CTD | PMID:35811015 | Cachd1 | Rat | lipopolysaccharide | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of CACHD1 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... | CTD | PMID:35811015 | Cachd1 | Rat | mercury dibromide | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of CACHD1 mRNA | CTD | PMID:26272509 | Cachd1 | Rat | mercury dibromide | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Cachd1 | Rat | methapyrilene | increases methylation | ISO | CACHD1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of CACHD1 promoter | CTD | PMID:30157460 | Cachd1 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of CACHD1 gene | CTD | PMID:35440735 | Cachd1 | Rat | methylmercury chloride | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of CACHD1 mRNA | CTD | PMID:28001369 | Cachd1 | Rat | nickel sulfate | increases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of CACHD1 mRNA | CTD | PMID:22714537 | Cachd1 | Rat | okadaic acid | increases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of CACHD1 mRNA | CTD | PMID:38832940 | Cachd1 | Rat | p-chloromercuribenzoic acid | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of CACHD1 mRNA | CTD | PMID:26272509 | Cachd1 | Rat | paracetamol | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of CACHD1 mRNA | CTD | PMID:26690555 | Cachd1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of CACHD1 mRNA | CTD | PMID:33387578 | Cachd1 | Rat | pentachlorophenol | increases expression | ISO | Cachd1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of CACHD1 mRNA | CTD | PMID:23892564 | Cachd1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Cachd1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CACHD1 mRNA | CTD | PMID:36331819 | Cachd1 | Rat | pirinixic acid | multiple interactions | ISO | Cachd1 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Cachd1 | Rat | rotenone | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of CACHD1 mRNA | CTD | PMID:29955902 | Cachd1 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of CACHD1 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... | CTD | PMID:35811015 | Cachd1 | Rat | SB 431542 | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Cachd1 | Rat | sodium arsenite | increases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of CACHD1 mRNA | CTD | PMID:22714537 | Cachd1 | Rat | tamoxifen | affects expression | ISO | Cachd1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of CACHD1 mRNA | CTD | PMID:17555576 | Cachd1 | Rat | tetrachloromethane | decreases expression | ISO | Cachd1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of CACHD1 mRNA | CTD | PMID:17484886 | Cachd1 | Rat | titanium dioxide | decreases methylation | ISO | Cachd1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of CACHD1 gene | CTD | PMID:35295148 | Cachd1 | Rat | titanium dioxide | increases methylation | ISO | CACHD1 (Homo sapiens) | 6480464 | titanium dioxide results in increased methylation of CACHD1 gene | CTD | PMID:34973136 | Cachd1 | Rat | trichostatin A | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of CACHD1 mRNA | CTD | PMID:24935251|PMID:26272509 | Cachd1 | Rat | trichostatin A | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Cachd1 | Rat | trimellitic anhydride | decreases expression | ISO | Cachd1 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of CACHD1 mRNA | CTD | PMID:19042947 | Cachd1 | Rat | urethane | increases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Urethane results in increased expression of CACHD1 mRNA | CTD | PMID:28818685 | Cachd1 | Rat | valproic acid | decreases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CACHD1 mRNA | CTD | PMID:24383497|PMID:26272509|PMID:28001369 | Cachd1 | Rat | valproic acid | multiple interactions | ISO | CACHD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Cachd1 | Rat | valproic acid | increases expression | ISO | CACHD1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CACHD1 mRNA | CTD | PMID:23179753|PMID:27188386|PMID:29154799 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















