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Gene: Rnf215 (ring finger protein 215) Rattus norvegicus

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Symbol:

Rnf215

Name:

ring finger protein 215

RGD ID:

1310738

Description:

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human RNF215 (ring finger protein 215); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC305478; RGD1310738; similar to RIKEN cDNA 0610009J22

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNF215 (ring finger protein 215)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rnf215 (ring finger protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnf215 (ring finger protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNF215 (ring finger protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RNF215 (ring finger protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf215 (ring finger protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNF215 (ring finger protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RNF215 (ring finger protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnf215 (ring finger protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rnf215 (ring finger protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Rnf215 (ring finger protein 215)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RNF215 (ring finger protein 215)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rnf215 (ring finger protein 215)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	83,230,234 - 83,236,668 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	83,230,265 - 83,236,668 (+)	Ensembl				GRCr8
mRatBN7.2	14	79,006,659 - 79,013,091 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	79,006,688 - 79,013,091 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	83,447,346 - 83,453,743 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	84,687,425 - 84,693,822 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	81,133,330 - 81,139,727 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	84,368,440 - 84,374,879 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	84,368,476 - 84,374,879 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	85,050,114 - 85,056,544 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	84,761,366 - 84,767,769 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	77,917,685 - 77,924,088 (+)	NCBI		Celera
RGSC_v3.1	14	84,780,591 - 84,785,643 (+)	NCBI
Cytogenetic Map	14	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

C60 fullerene (EXP)

carbon nanotube (ISO)

cisplatin (ISO)

DDE (ISO)

decabromodiphenyl ether (EXP)

dexamethasone (ISO)

dicrotophos (ISO)

folic acid (ISO)

GSK-J4 (ISO)

indometacin (ISO)

methimazole (EXP)

niclosamide (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

thioacetamide (EXP)

triphenyl phosphate (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ubiquitin-dependent protein catabolic process (IBA)

Cellular Component

cytoplasm (IBA)

membrane (IEA)

Molecular Function

metal ion binding (IEA)

ubiquitin protein ligase activity (IBA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Rnf215
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	83,230,234 - 83,236,668 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	83,230,265 - 83,236,668 (+)	Ensembl				GRCr8
mRatBN7.2	14	79,006,659 - 79,013,091 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	79,006,688 - 79,013,091 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	83,447,346 - 83,453,743 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	84,687,425 - 84,693,822 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	81,133,330 - 81,139,727 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	84,368,440 - 84,374,879 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	84,368,476 - 84,374,879 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	85,050,114 - 85,056,544 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	84,761,366 - 84,767,769 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	77,917,685 - 77,924,088 (+)	NCBI		Celera
RGSC_v3.1	14	84,780,591 - 84,785,643 (+)	NCBI
Cytogenetic Map	14	q21	NCBI

RNF215
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	30,378,821 - 30,387,411 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	30,368,811 - 30,421,771 (-)	Ensembl			hg38	GRCh38
GRCh37	22	30,774,810 - 30,783,400 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	29,104,801 - 29,113,302 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	22	14,574,485 - 14,582,986 (-)	NCBI		Celera
Cytogenetic Map	22	q12.2	NCBI
HuRef	22	13,736,484 - 13,754,618 (-)	NCBI		HuRef
CHM1_1	22	30,733,975 - 30,742,458 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	22	30,842,154 - 30,850,743 (-)	NCBI		T2T-CHM13v2.0

Rnf215
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	4,085,158 - 4,091,193 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	4,085,202 - 4,091,172 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	4,135,157 - 4,141,193 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	4,135,202 - 4,141,172 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	4,035,163 - 4,041,196 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	4,035,205 - 4,041,175 (+)	NCBI		MGSCv36	mm8
Celera	11	4,631,504 - 4,637,537 (+)	NCBI		Celera
Cytogenetic Map	11	A1	NCBI
cM Map	11	2.89	NCBI

Rnf215
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	4,616,347 - 4,621,982 (-)	Ensembl
ChiLan1.0	NW_004955455	4,616,347 - 4,621,982 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNF215
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	40,345,882 - 40,354,477 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	43,044,518 - 43,053,108 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	11,414,856 - 11,423,452 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	29,216,232 - 29,224,402 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

RNF215
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	23,520,438 - 23,527,663 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	23,521,248 - 23,527,607 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	23,391,487 - 23,398,674 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	23,904,528 - 23,911,710 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	23,905,463 - 23,911,710 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	23,605,970 - 23,613,159 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	23,868,780 - 23,875,953 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	23,929,146 - 23,936,332 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rnf215
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	116,439,039 - 116,445,310 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936904	288,773 - 298,725 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936904	288,838 - 295,183 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF215
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	47,351,305 - 47,357,149 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	47,351,296 - 47,357,191 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	50,434,408 - 50,441,670 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF215
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	13,258,187 - 13,266,470 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666045	112,880,171 - 112,888,664 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnf215
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	6,695,753 - 6,715,846 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	6,686,044 - 6,702,177 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rnf215
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	73,117,958 - 73,123,957 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rnf215
39 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	163
Count of miRNA genes:	118
Interacting mature miRNAs:	145
Transcripts:	ENSRNOT00000006827
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590294	Uminl4	Urine mineral level QTL 4	5.66	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	14	59848686	104848686	Rat
1582236	Gluco22	Glucose level QTL 22	3.3	0.0164	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	96755654	Rat
2300197	Scl59	Serum cholesterol level QTL 59			blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	77914838	104348525	Rat
70214	Niddm28	Non-insulin dependent diabetes mellitus QTL 28	4.06		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	39009444	84009444	Rat
70153	Bp59	Blood pressure QTL 59	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	14	72970210	87582095	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30674469	85041098	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	33424686	102238540	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	74255551	109089856	Rat
1582197	Gluco27	Glucose level QTL 27	3.4	0.0006	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	77640071	96755654	Rat
634328	Hc5	Hypercalciuria QTL 5	2.3		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	14	62398852	107398852	Rat
1582250	Gluco26	Glucose level QTL 26	3.3	0.0009	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	100078267	Rat
2317879	Alcrsp27	Alcohol response QTL 27	3.3	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	14	60854936	105854936	Rat
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	74255551	109089856	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	100078267	Rat
1582255	Gluco29	Glucose level QTL 29	3.1	0.0025	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	14	77640071	96755654	Rat
9589034	Epfw11	Epididymal fat weight QTL 11	6	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	14	59848686	104848686	Rat
1582209	Gluco20	Glucose level QTL 20	3.8	0.0005	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	96755654	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42616258	99224555	Rat
1549834	Scl45	Serum cholesterol level QTL 45	5.8		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	65920283	99224555	Rat
738037	Hcas6	Hepatocarcinoma susceptibility QTL 6	2.93		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	14	39411170	87582095	Rat

Markers in Region

RH133061

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	79,012,174 - 79,012,380 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	84,373,963 - 84,374,168	NCBI	Rnor6.0
Rnor_5.0	14	85,055,628 - 85,055,833	UniSTS	Rnor5.0
RGSC_v3.4	14	84,766,853 - 84,767,058	UniSTS	RGSC3.4
Celera	14	77,923,172 - 77,923,377	UniSTS
RH 3.4 Map	14	543.0	UniSTS
Cytogenetic Map	14	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001436907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599223	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006827 ⟹ ENSRNOP00000006827

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	83,230,265 - 83,236,668 (+)	Ensembl
mRatBN7.2 Ensembl	14	79,006,688 - 79,013,091 (+)	Ensembl
Rnor_6.0 Ensembl	14	84,368,476 - 84,374,879 (+)	Ensembl

RefSeq Acc Id:

NM_001107234 ⟹ NP_001100704

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,230,265 - 83,236,668 (+)	NCBI
mRatBN7.2	14	79,006,688 - 79,013,091 (+)	NCBI
Rnor_6.0	14	84,368,476 - 84,374,879 (+)	NCBI
Rnor_5.0	14	85,050,114 - 85,056,544 (+)	NCBI
RGSC_v3.4	14	84,761,366 - 84,767,769 (+)	RGD
Celera	14	77,917,685 - 77,924,088 (+)	RGD

Sequence:

show sequence

CCGGCGCGGCCTGGCTCACTCGGTTCTCCTGGCCCCCCCGCGGACCTTAGACTACGGCCTCACC
ACCTCTCCGGTCCGGTCATGGGCCCGGCCGATCGCCCGGCACTGAGGTCGCCATCTTCGCCGCC
CCCTCCCCCATCGCCGCCGTCGCCGCTGCTGCTACTGTTGCCCCTGCTGCCTTTGTGGCTGGGC
CTGATGGGTCCCGGAGCCGCGGCGGACGGCAGCGAGCCGGAGGCCCGGGCTGGGCGGGGCGGAG
CCCGCGCAGTGCGGGTGGATGTGAAGCTGCCGCGGCAGGACGCCCTGGTTTTGGAGGGTGTCAG
GATCGGTTCCGAAGCGAGTCCGGAACCTCTACTGGGCGGCCGCCTGCTGCTGATGGATGTCGTG
GATGCTGAGCAAGAGATACCCGCAGATGGCTGGATTGCAGTGGCATATGTGGGCAAAGAGCAGG
TCGCCCAGTTCCACCAGGAGAATCAAGGCAGTAGCCAGAAGGCATATCCCAAGGCTCTGGTCCA
GCAGATGCGCCGAGCCCTTTTCCTGGGAGCCTCTGCCCTGCTTCTCCTCATCCTAAACCACAGT
GTAGTCCGAGAGTTGGACATATCCCAGCTCCTGCTCAGGCCAGTGATTGTTCTCCATTACTCTT
CAAATGTCACCAAGCTGTTGGAAGCTCTTCTGCAGAGGACCCAGGCTACTGCTGAGATCAGCAG
TGGAGAGTCCCTTTCAGCCAACATCGAGTGGAAGCTGACATTGTGGACCACCTGTGGTCTCTCC
AAGGATGGCTACGGTGGCTGGCAGGACTTGGTGTGCCTGGGAGGTGCTCAAGCCCAGGAGCAGA
AGCCCCTGCAGCAGCTATGGAATGCCATCTTGCTTGTGGTCATGCTCTTGTGCACAGGCCTTGT
GGTTCAGGCCCAACGGCAGGCATCAAGACAGAGCCAGCAGGAGCCTGGAGGCCAGGAGGATTTG
TTCAAACGCCGTGTGGTTCGGAGACTAGCATCCCTCAAGACCCGGCGGTGCCGGCTGAGCAGGG
CAGCACACAGCCTTCCAGAGCCTGGCGCTGAGACTTGCGCTGTCTGTCTTGATTACTTCTGTAA
CAAGCAGTGGCTCCGGGTACTGCCCTGTAAGCATGAGTTCCACCGAGACTGCGTAGACCCCTGG
CTGATGCTACAACAGACCTGCCCACTGTGCAAGTTCAATGTCCTGGGGAACCACTACTCAGATG
ACTAACTCCCCAGTGGAGAGTCTGCACATCGGGATGGACCCTTCCCAGCCTACACTACAGGAGA
GTGGGATGGGCAGACCAGCTAGCCCTGTGGGCAAAGGAAAGGTTCCCACCATGCCCATGATGGA
TAGGAGGGACTCGCACCTCCAGGCTGAAGACACAGAGCCAGGACCCAGCAGGCAAGGAGAAATC
ATTAGAGCCCTTCTCTGCAAACCTGGGGTATTGTGTCTGTCCTCATAGGCAGCTCCCACAACTC
TGGGAAAGAAAATATGGCCACTACATCTGTCCACAGCACTCTGGAGCTTCGGTGTTGAATTTTA
TGCTATTTATTGAGGGAGAATATGTGTGGCCATGGGACCCACTGGCATGACCGTGTCTTTCGGG
CCATGGCCTAATCAAATCAAAGATGACGTTAAAGTGAGCCTGCTCCACTCCCTGCTGCCCGTCC
AGCTGGATTCCTCCAGTCTGACTGGGATCAGAGGCCTTAGAAACCATCTAGTGCTGTATTTCTT
GGTTGGCCTAAATGTTACTGCAGGATACTTGAGGCCACAGAATACATGTGGTGCATCTGCCAAG
GGCATCATTACAAGAAAAAAACAAAAACACAAAAACAAATGTTTGGGTAGGGAAGTTTTAATAG
TAAAATAAACATGGAGTATATTTTAACATATAAGACATAAATCTGTGTGATGTTTTAAGATGTT
AAGGAAAAGATGGATATGTGGTGGCATATGCCAATAATCCCAGAAACCTGGAGTTGGAGACAGG
AGGATTAAGAGTTCAAGGCCAGCTGGGCACAGTAGTGTACCCCTTTAGTCCTAGCACTGGTGAG
GCAGAGGCAGGCAGATCTCTGTGAATTCAAGCCCAGCCTGGTCTACATAGTAAGTTCCAAGACA
GCCAGGGCTACACAGAGAGACCCTGTCTCAAATAACAAAACAAAACAAAAAGTTCAAGGCTAAA
CTGGGCTCCTGGGCAGTCCCTGTAATCCCCTTGTTCTGTAGCCTCTGGTAAGGGAAACCAGAGG
GTCATGAACTCTCGATCATCCTTGGCTGCATAGACAAGCCTGGGCTACTCTCAAAGAGAAAAAC
AGACGAAAACCAATCACCTTGGTTTCTCTTGCTGGGAACAGTAGAATCCTTACATTCCTCAAGG
CCTTGCACTATCTTTAAAATGTTGACTCTAGAAATTCTAGCCCCTGTGAGTAGGTTATGTAGAG
TGATCTTCAGATGAGAGGCAAGGGCTGGGGCATGGCGCGAACTGGTAGAGAACCTGCCTC

hide sequence

RefSeq Acc Id:

XM_006251300 ⟹ XP_006251362

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,230,235 - 83,236,073 (+)	NCBI
mRatBN7.2	14	79,006,660 - 79,012,485 (+)	NCBI
Rnor_6.0	14	84,368,442 - 84,374,284 (+)	NCBI
Rnor_5.0	14	85,050,114 - 85,056,544 (+)	NCBI

Sequence:

show sequence

GCCCCGCCCCTCCCGGTGCCGCGCCCCGCCCCGTCCGGCGCGGCCTGGCTCACTCGGTTCTCCT
GGCCCCCCCGCGGACCTTAGACTACGGCCTCACCACCTCTCCGGTCCGGTCATGGGCCCGGCCG
ATCGCCCGGCACTGAGGTCGCCATCTTCGCCGCCCCCTCCCCCATCGCCGCCGTCGCCGCTGCT
GCTACTGTTGCCCCTGCTGCCTTTGTGGCTGGGCCTGATGGGTCCCGGAGCCGCGGCGGACGGC
AGCGAGCCGGAGGCCCGGGCTGGGCGGGGCGGAGCCCGCGCAGTGCGGGTGGATGTGAAGCTGC
CGCGGCAGGACGCCCTGGTTTTGGAGGGTGTCAGGATCGGTTCCGAAGCGAGTCCGGAACCTCT
ACTGGGCGGCCGCCTGCTGCTGATGGATGTCGTGGATGCTGAGCAAGAGATACCCGCAGATGGC
TGGATTGCAGTGGCATATGTGGGCAAAGAGCAGGTCGCCCAGTTCCACCAGGAGAATCAAGGCA
GTAGCCAGAAGGCATATCCCAAGGCTCTGGTCCAGCAGATGCGCCGAGCCCTTTTCCTGGGAGC
CTCTGCCCTGCTTCTCCTCATCCTAAACCACAGTGTAGTCCGAGAGTTGGACATATCCCAGCTC
CTGCTCAGGCCAGTGATTGTTCTCCATTACTCTTCAAATGTCACCAAGCTGTTGGAAGCTCTTC
TGCAGAGGACCCAGGCTACTGCTGAGATCAGCAGTGGAGAGTCCCTTTCAGCCAACATCGAGTG
GAAGCTGACATTGTGGACCACCTGTGGTCTCTCCAAGGATGGCTACGGTGGCTGGCAGGACTTG
GTGTGCCTGGGAGGTGCTCAAGCCCAGGAGCAGAAGCCCCTGCAGCAGCTATGGAATGCCATCT
TGCTTGTGGTCATGCTCTTGTGCACAGGCCTTGTGGTTCAGGCCCAACGGCAGGCATCAAGACA
GAGCCAGCAGGAGCCTGGAGGCCAGGAGGATTTGTTCAAACGCCGTGTGGTTCGGAGACTAGCA
TCCCTCAAGACCCGGCGGTGCCGGCTGAGCAGGGCAGCACACAGCCTTCCAGAGCCTGGCGCTG
AGACTTGCGCTGTCTGTCTTGATTACTTCTGTAACAAGCAGTGGCTCCGGGTACTGCCCTGTAA
GCATGAGTTCCACCGAGACTGCGTAGACCCCTGGCTGATGCTACAACAGACCTGCCCACTGTGC
AAGTTCAATGTCCTGGGTGAGCACCAGGGGCCAGGTGGGATCCTGGGCTAACTCCCTAAGCCCC
ACCTGATACCTCTCTCCCTGTCCTTCCTTTCCCTACAGGGAACCACTACTCAGATGACTAACTC
CCCAGTGGAGAGTCTGCACATCGGGATGGACCCTTCCCAGCCTACACTACAGGAGAGTGGGATG
GGCAGACCAGCTAGCCCTGTGGGCAAAGGAAAGGTTCCCACCATGCCCATGATGGATAGGAGGG
ACTCGCACCTCCAGGCTGAAGACACAGAGCCAGGACCCAGCAGGCAAGGAGAAATCATTAGAGC
CCTTCTCTGCAAACCTGGGGTATTGTGTCTGTCCTCATAGGCAGCTCCCACAACTCTGGGAAAG
AAAATATGGCCACTACATCTGTCCACAGCACTCTGGAGCTTCGGTGTTGAATTTTATGCTATTT
ATTGAGGGAGAATATGTGTGGCCATGGGACCCACTGGCATGACCGTGTCTTTCGGGCCATGGCC
TAATCAAATCAAAGATGACGTTAAAGTGAGCCTGCTCCACTCCCTGCTGCCCGTCCAGCTGGAT
TCCTCCAGTCTGACTGGGATCAGAGGCCTTAGAAACCATCTAGTGCTGTATTTCTTGGTTGGCC
TAAATGTTACTGCAGGATACTTGAGGCCACAGAATACATGTGGTGCATCTGCCAAGGGCATCAT
TACAAGAAAAAAACAAAAACACAAAAACAAATGTTTGGGTAGGGAAGTTTTAATAGTAAAATAA
ACATGGAGTATATTTTAACATATAAGACATAAA

hide sequence

RefSeq Acc Id:

XM_017599223 ⟹ XP_017454712

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,230,234 - 83,236,073 (+)	NCBI
mRatBN7.2	14	79,006,659 - 79,012,485 (+)	NCBI
Rnor_6.0	14	84,368,440 - 84,374,284 (+)	NCBI

Sequence:

show sequence

CGGCCCCGCCCCTCCCGGTGCCGCGCCCCGCCCCGTCCGGCGCGGCCTGGCTCACTCGGTTCTC
CTGGCCCCCCCGCGGACCTTAGACTACGGCCTCACCACCTCTCCGGTCCGGTCATGGGCCCGGC
CGATCGCCCGGCACTGAGGTCGCCATCTTCGCCGCCCCCTCCCCCATCGCCGCCGTCGCCGCTG
CTGCTACTGTTGCCCCTGCTGCCTTTGTGGCTGGGCCTGATGGGTCCCGGAGCCGCGGCGGACG
GCAGCGAGCCGGAGGCCCGGGCTGGGCGGGGCGGAGCCCGCGCAGTGCGGGTGGATGTGAAGCT
GCCGCGGCAGGACGCCCTGGTTTTGGAGGGTGTCAGGATCGGTTCCGAAGCGAGTCCGGAACCT
CTACTGGGCGGCCGCCTGCTGCTGATGGATGTCGTGGATGCTGAGCAAGAGATACCCGCAGATG
GCTGGATTGCAGTGGCATATGTGGGCAAAGAGCAGGTCGCCCAGTTCCACCAGGAGAATCAAGG
CAGTAGCCAGAAGGCATATCCCAAGGCTCTGGTCCAGCAGATGCGCCGAGCCCTTTTCCTGGGA
GCCTCTGCCCTGCTTCTCCTCATCCTAAACCACAGTGTAGTCCGAGAGTTGGACATATCCCAGC
TCCTGCTCAGGCCAGTGATTGTTCTCCATTACTCTTCAAATGTCACCAAGCTGTTGGAAGCTCT
TCTGCAGAGGACCCAGGCTACTGCTGAGATCAGCAGTGGAGAGTCCCTTTCAGCCAACATCGAG
TGGAAGCTGACATTGTGGACCACCTGTGGTCTCTCCAAGGATGGCTACGGTGGCTGGCAGGACT
TGGTGTGCCTGGGAGGTGCTCAAGCCCAGGAGCAGGAGGATTTGTTCAAACGCCGTGTGGTTCG
GAGACTAGCATCCCTCAAGACCCGGCGGTGCCGGCTGAGCAGGGCAGCACACAGCCTTCCAGAG
CCTGGCGCTGAGACTTGCGCTGTCTGTCTTGATTACTTCTGTAACAAGCAGTGGCTCCGGGTAC
TGCCCTGTAAGCATGAGTTCCACCGAGACTGCGTAGACCCCTGGCTGATGCTACAACAGACCTG
CCCACTGTGCAAGTTCAATGTCCTGGGTGAGCACCAGGGGCCAGGTGGGATCCTGGGCTAACTC
CCTAAGCCCCACCTGATACCTCTCTCCCTGTCCTTCCTTTCCCTACAGGGAACCACTACTCAGA
TGACTAACTCCCCAGTGGAGAGTCTGCACATCGGGATGGACCCTTCCCAGCCTACACTACAGGA
GAGTGGGATGGGCAGACCAGCTAGCCCTGTGGGCAAAGGAAAGGTTCCCACCATGCCCATGATG
GATAGGAGGGACTCGCACCTCCAGGCTGAAGACACAGAGCCAGGACCCAGCAGGCAAGGAGAAA
TCATTAGAGCCCTTCTCTGCAAACCTGGGGTATTGTGTCTGTCCTCATAGGCAGCTCCCACAAC
TCTGGGAAAGAAAATATGGCCACTACATCTGTCCACAGCACTCTGGAGCTTCGGTGTTGAATTT
TATGCTATTTATTGAGGGAGAATATGTGTGGCCATGGGACCCACTGGCATGACCGTGTCTTTCG
GGCCATGGCCTAATCAAATCAAAGATGACGTTAAAGTGAGCCTGCTCCACTCCCTGCTGCCCGT
CCAGCTGGATTCCTCCAGTCTGACTGGGATCAGAGGCCTTAGAAACCATCTAGTGCTGTATTTC
TTGGTTGGCCTAAATGTTACTGCAGGATACTTGAGGCCACAGAATACATGTGGTGCATCTGCCA
AGGGCATCATTACAAGAAAAAAACAAAAACACAAAAACAAATGTTTGGGTAGGGAAGTTTTAAT
AGTAAAATAAACATGGAGTATATTTTAACATATAAGACATAAA

hide sequence

RefSeq Acc Id:

XM_063273206 ⟹ XP_063129276

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,230,235 - 83,236,073 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100704	(Get FASTA)	NCBI Sequence Viewer
	NP_001423836	(Get FASTA)	NCBI Sequence Viewer
	XP_006251362	(Get FASTA)	NCBI Sequence Viewer
	XP_017454712	(Get FASTA)	NCBI Sequence Viewer
	XP_063129276	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM00213	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006827
	ENSRNOP00000006827.2

RefSeq Acc Id:	NP_001100704 ⟸ NM_001107234
- Peptide Label:	precursor
- UniProtKB:	D3ZNU0 (UniProtKB/TrEMBL), A6IKE9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGPADRPALRSPSSPPPPPSPPSPLLLLLPLLPLWLGLMGPGAAADGSEPEARAGRGGARAVRV DVKLPRQDALVLEGVRIGSEASPEPLLGGRLLLMDVVDAEQEIPADGWIAVAYVGKEQVAQFHQ ENQGSSQKAYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKL LEALLQRTQATAEISSGESLSANIEWKLTLWTTCGLSKDGYGGWQDLVCLGGAQAQEQKPLQQL WNAILLVVMLLCTGLVVQAQRQASRQSQQEPGGQEDLFKRRVVRRLASLKTRRCRLSRAAHSLP EPGAETCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNHYSDD hide sequence

RefSeq Acc Id:

XP_006251362 ⟸ XM_006251300

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGPADRPALRSPSSPPPPPSPPSPLLLLLPLLPLWLGLMGPGAAADGSEPEARAGRGGARAVRV
DVKLPRQDALVLEGVRIGSEASPEPLLGGRLLLMDVVDAEQEIPADGWIAVAYVGKEQVAQFHQ
ENQGSSQKAYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKL
LEALLQRTQATAEISSGESLSANIEWKLTLWTTCGLSKDGYGGWQDLVCLGGAQAQEQKPLQQL
WNAILLVVMLLCTGLVVQAQRQASRQSQQEPGGQEDLFKRRVVRRLASLKTRRCRLSRAAHSLP
EPGAETCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGEHQGPGGILG

hide sequence

RefSeq Acc Id:

XP_017454712 ⟸ XM_017599223

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGPADRPALRSPSSPPPPPSPPSPLLLLLPLLPLWLGLMGPGAAADGSEPEARAGRGGARAVRV
DVKLPRQDALVLEGVRIGSEASPEPLLGGRLLLMDVVDAEQEIPADGWIAVAYVGKEQVAQFHQ
ENQGSSQKAYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKL
LEALLQRTQATAEISSGESLSANIEWKLTLWTTCGLSKDGYGGWQDLVCLGGAQAQEQEDLFKR
RVVRRLASLKTRRCRLSRAAHSLPEPGAETCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLML
QQTCPLCKFNVLGEHQGPGGILG

hide sequence

Ensembl Acc Id:

ENSRNOP00000006827 ⟸ ENSRNOT00000006827

RefSeq Acc Id:	XP_063129276 ⟸ XM_063273206
- Peptide Label:	isoform X3

Protein Domains

RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZNU0-F1-model_v2	AlphaFold	D3ZNU0	1-379	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699440

Promoter ID:

EPDNEW_R9964

Type:

initiation region

Name:

Rnf215_1

Description:

ring finger protein 215

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	84,368,524 - 84,368,584	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310738	AgrOrtholog
BioCyc Gene	G2FUF-15185	BioCyc
Ensembl Genes	ENSRNOG00000004940	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006827	ENTREZGENE
	ENSRNOT00000006827.5	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
	3.50.30.30	UniProtKB/TrEMBL
InterPro	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	ZNRF3_Arkadia_E3_ligases	UniProtKB/TrEMBL
KEGG Report	rno:305478	UniProtKB/TrEMBL
NCBI Gene	305478	ENTREZGENE
PANTHER	RING ZINC FINGER	UniProtKB/TrEMBL
Pfam	zf-RING_2	UniProtKB/TrEMBL
PhenoGen	Rnf215	PhenoGen
PROSITE	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004940	RatGTEx
SMART	RING	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
UniProt	A6IKE9	ENTREZGENE, UniProtKB/TrEMBL
	D3ZNU0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-27	Rnf215	ring finger protein 215	RGD1310738_predicted	similar to RIKEN cDNA 0610009J22 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1310738_predicted	similar to RIKEN cDNA 0610009J22 (predicted)	LOC305478_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC305478_predicted	similar to RIKEN cDNA 0610009J22 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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