Atg16l1 (autophagy related 16-like 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Atg16l1 (autophagy related 16-like 1) Rattus norvegicus
Analyze
Symbol: Atg16l1
Name: autophagy related 16-like 1
RGD ID: 1310631
Description: Predicted to enable GTPase binding activity; identical protein binding activity; and protein-membrane adaptor activity. Involved in dendrite arborization and negative regulation of dendrite extension. Is active in glutamatergic synapse. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Orthologous to human ATG16L1 (autophagy related 16 like 1); PARTICIPATES IN autophagy pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: APG16 autophagy 16-like; APG16 autophagy 16-like (S. cerevisiae); Apg16l; ATG16 autophagy related 16-like 1; ATG16 autophagy related 16-like 1 (S. cerevisiae); autophagy related 16-like 1 (S. cerevisiae); autophagy-related 16-like 1; autophagy-related 16-like 1 (yeast); autophagy-related protein 16-1; LOC363278; WD repeat domain 30; Wdr30
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Atg16l1em8Rrrc
Genetic Models: F344-Atg16l1em8Rrrc
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,869,839 - 95,905,354 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl995,869,865 - 95,905,357 (+)EnsemblGRCr8
mRatBN7.2988,420,737 - 88,457,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx996,846,724 - 96,882,032 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,982,902 - 102,018,214 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,350,405 - 100,385,741 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,879,876 - 94,915,231 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,879,745 - 94,915,228 (+)Ensemblrn6Rnor6.0
Rnor_5.0994,599,174 - 94,634,551 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4986,712,122 - 86,747,370 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera985,830,765 - 85,865,957 (+)NCBICelera
RGSC_v3.1986,895,541 - 86,929,665 (+)NCBI
Cytogenetic Map9q35NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Melatonin protects against developmental PBDE-47 neurotoxicity by targeting the AMPK/mitophagy axis. Dong L, etal., J Pineal Res. 2023 Aug;75(1):e12871. doi: 10.1111/jpi.12871. Epub 2023 Apr 27.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. δ-Catenin engages the autophagy pathway to sculpt the developing dendritic arbor. Ligon C, etal., J Biol Chem. 2020 Aug 7;295(32):10988-11001. doi: 10.1074/jbc.RA120.013058. Epub 2020 Jun 17.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Bassoon Controls Presynaptic Autophagy through Atg5. Okerlund ND, etal., Neuron. 2017 Feb 22;93(4):897-913.e7. doi: 10.1016/j.neuron.2017.01.026.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Hepatic interferon regulatory factor 8 expression mediates liver ischemia/reperfusion injury in mice. Shi G, etal., Biochem Pharmacol. 2021 Oct;192:114728. doi: 10.1016/j.bcp.2021.114728. Epub 2021 Aug 13.
11. LC3 conjugation system in mammalian autophagy. Tanida I, etal., Int J Biochem Cell Biol. 2004 Dec;36(12):2503-18.
12. Aliskiren ameliorates pressure overload-induced heart hypertrophy and fibrosis in mice. Weng LQ, etal., Acta Pharmacol Sin. 2014 Aug;35(8):1005-14. doi: 10.1038/aps.2014.45. Epub 2014 Jul 7.
13. Mammalian autophagy: core molecular machinery and signaling regulation. Yang Z and Klionsky DJ, Curr Opin Cell Biol. 2010 Apr;22(2):124-31. Epub 2009 Dec 23.
Additional References at PubMed
PMID:8889548   PMID:12665549   PMID:20562859   PMID:21220506   PMID:22740627   PMID:23392225   PMID:24089209   PMID:24550300   PMID:24954904   PMID:25891078   PMID:26845845   PMID:28860495  
PMID:29634390   PMID:30208760   PMID:33818130   PMID:33843019   PMID:35503135  


Genomics

Comparative Map Data
Atg16l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,869,839 - 95,905,354 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl995,869,865 - 95,905,357 (+)EnsemblGRCr8
mRatBN7.2988,420,737 - 88,457,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx996,846,724 - 96,882,032 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,982,902 - 102,018,214 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,350,405 - 100,385,741 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,879,876 - 94,915,231 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,879,745 - 94,915,228 (+)Ensemblrn6Rnor6.0
Rnor_5.0994,599,174 - 94,634,551 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4986,712,122 - 86,747,370 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera985,830,765 - 85,865,957 (+)NCBICelera
RGSC_v3.1986,895,541 - 86,929,665 (+)NCBI
Cytogenetic Map9q35NCBI
ATG16L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382233,251,673 - 233,295,669 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2233,210,051 - 233,295,674 (+)Ensemblhg38GRCh38
GRCh372234,160,319 - 234,204,315 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,824,956 - 233,869,059 (+)NCBIBuild 36Build 36hg18NCBI36
Celera2227,881,745 - 227,925,836 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2225,960,992 - 226,005,094 (+)NCBIHuRef
CHM1_12234,166,299 - 234,210,402 (+)NCBICHM1_1
T2T-CHM13v2.02233,739,756 - 233,783,753 (+)NCBIT2T-CHM13v2.0
Atg16l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,683,730 - 87,720,150 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,683,592 - 87,720,150 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38187,756,007 - 87,792,428 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,755,870 - 87,792,428 (+)Ensemblmm10GRCm38
MGSCv37189,652,646 - 89,688,997 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36189,587,242 - 89,623,593 (+)NCBIMGSCv36mm8
Celera190,714,013 - 90,750,352 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.44NCBI
Atg16l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554532,880,928 - 2,917,581 (-)Ensembl
ChiLan1.0NW_0049554532,884,497 - 2,917,581 (-)NCBIChiLan1.0ChiLan1.0
ATG16L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,853,482 - 135,897,461 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,868,447 - 135,912,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B120,479,534 - 120,523,563 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B239,392,990 - 239,436,766 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B239,392,990 - 239,436,766 (+)EnsemblpanPan2panpan1.1
ATG16L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,761,034 - 44,800,033 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,761,185 - 44,798,672 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2545,256,465 - 45,295,672 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02545,020,993 - 45,060,197 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2545,020,983 - 45,060,197 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12544,945,410 - 44,984,592 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,791,409 - 44,830,551 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02544,946,602 - 44,985,778 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Atg16l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,929,271 - 186,966,233 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365253,972,558 - 4,010,514 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365253,973,574 - 4,010,442 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATG16L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,651,298 - 133,693,468 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115133,651,294 - 133,693,472 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215147,677,835 - 147,718,756 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATG16L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110119,286,609 - 119,331,226 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10119,286,751 - 119,333,267 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604080,173,329 - 80,218,029 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atg16l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248435,805,069 - 5,838,741 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248435,797,725 - 5,838,768 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Atg16l1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14159,870,694 - 159,906,616 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Atg16l1
223 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:464
Count of miRNA genes:239
Interacting mature miRNAs:299
Transcripts:ENSRNOT00000024445
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)986720043110356905Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)985262459109044727Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat

Markers in Region
BE120484  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2988,450,809 - 88,450,973 (+)MAPPERmRatBN7.2
Rnor_6.0994,908,513 - 94,908,676NCBIRnor6.0
Rnor_5.0994,627,833 - 94,627,996UniSTSRnor5.0
RGSC_v3.4986,740,651 - 86,740,814UniSTSRGSC3.4
Celera985,859,238 - 85,859,401UniSTS
Cytogenetic Map9q35UniSTS
RH137932  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2988,449,736 - 88,449,911 (+)MAPPERmRatBN7.2
Rnor_6.0994,907,440 - 94,907,614NCBIRnor6.0
Rnor_5.0994,626,760 - 94,626,934UniSTSRnor5.0
RGSC_v3.4986,739,578 - 86,739,752UniSTSRGSC3.4
Celera985,858,165 - 85,858,339UniSTS
Cytogenetic Map9q35UniSTS
RH139068  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2988,453,825 - 88,453,993 (+)MAPPERmRatBN7.2
Rnor_6.0994,911,525 - 94,911,692NCBIRnor6.0
Rnor_5.0994,630,845 - 94,631,012UniSTSRnor5.0
RGSC_v3.4986,743,667 - 86,743,834UniSTSRGSC3.4
Celera985,862,254 - 85,862,421UniSTS
Cytogenetic Map9q35UniSTS


Genetic Models
This gene Atg16l1 is modified in the following models/strains:
F344-Atg16l1em8Rrrc    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA925215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB605957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB782885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK473997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK481169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO393878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EV774911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000024445   ⟹   ENSRNOP00000024445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl995,869,865 - 95,905,357 (+)Ensembl
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)Ensembl
Rnor_6.0 Ensembl994,880,053 - 94,915,228 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080482   ⟹   ENSRNOP00000075135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl995,869,865 - 95,905,351 (+)Ensembl
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)Ensembl
Rnor_6.0 Ensembl994,879,745 - 94,915,204 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114063   ⟹   ENSRNOP00000097226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl995,869,865 - 95,905,351 (+)Ensembl
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)Ensembl
RefSeq Acc Id: NM_001108809   ⟹   NP_001102279
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,870,013 - 95,905,354 (+)NCBI
mRatBN7.2988,422,181 - 88,457,529 (+)NCBI
Rnor_6.0994,880,053 - 94,915,228 (+)NCBI
Rnor_5.0994,599,174 - 94,634,551 (+)NCBI
RGSC_v3.4986,712,122 - 86,747,370 (+)RGD
Celera985,830,765 - 85,865,957 (+)RGD
Sequence:
RefSeq Acc Id: XM_006245419   ⟹   XP_006245481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,869,839 - 95,905,354 (+)NCBI
mRatBN7.2988,421,916 - 88,457,530 (+)NCBI
Rnor_6.0994,879,876 - 94,915,231 (+)NCBI
Rnor_5.0994,599,174 - 94,634,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006245420   ⟹   XP_006245482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,869,840 - 95,905,354 (+)NCBI
mRatBN7.2988,421,942 - 88,457,530 (+)NCBI
Rnor_6.0994,879,876 - 94,915,231 (+)NCBI
Rnor_5.0994,599,174 - 94,634,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083917   ⟹   XP_038939845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,869,839 - 95,905,354 (+)NCBI
mRatBN7.2988,420,737 - 88,457,530 (+)NCBI
RefSeq Acc Id: XM_063267450   ⟹   XP_063123520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,869,839 - 95,905,354 (+)NCBI
RefSeq Acc Id: XM_063267451   ⟹   XP_063123521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,884,824 - 95,905,354 (+)NCBI
RefSeq Acc Id: XM_063267452   ⟹   XP_063123522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,884,824 - 95,905,354 (+)NCBI
RefSeq Acc Id: NP_001102279   ⟸   NM_001108809
- UniProtKB: D3ZFK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245481   ⟸   XM_006245419
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K9U6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245482   ⟸   XM_006245420
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GLZ1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075135   ⟸   ENSRNOT00000080482
Ensembl Acc Id: ENSRNOP00000024445   ⟸   ENSRNOT00000024445
RefSeq Acc Id: XP_038939845   ⟸   XM_039083917
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000097226   ⟸   ENSRNOT00000114063
RefSeq Acc Id: XP_063123520   ⟸   XM_063267450
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063123521   ⟸   XM_063267451
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063123522   ⟸   XM_063267452
- Peptide Label: isoform X6
Protein Domains
Autophagy-related protein

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K9U6-F1-model_v2 AlphaFold A0A0G2K9U6 1-623 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696840
Promoter ID:EPDNEW_R7364
Type:multiple initiation site
Name:Atg16l1_1
Description:autophagy related 16-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0994,879,907 - 94,879,967EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310631 AgrOrtholog
BioCyc Gene G2FUF-26835 BioCyc
Ensembl Genes ENSRNOG00000017913 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024445 ENTREZGENE
  ENSRNOT00000024445.5 UniProtKB/TrEMBL
  ENSRNOT00000080482 ENTREZGENE
  ENSRNOT00000080482.3 UniProtKB/TrEMBL
  ENSRNOT00000114063 ENTREZGENE
  ENSRNOT00000114063.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro ATG16 UniProtKB/TrEMBL
  Autophagy-rel_prot_16 UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep_reg UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:363278 UniProtKB/TrEMBL
NCBI Gene 363278 ENTREZGENE
PANTHER AUTOPHAGY-RELATED PROTEIN 16-1 UniProtKB/TrEMBL
  PTHR19878 UniProtKB/TrEMBL
Pfam ATG16 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Atg16l1 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017913 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A0G2K9U6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLZ1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZFK6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-24 Atg16l1  autophagy related 16-like 1  Atg16l1  autophagy related 16-like 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-06-07 Atg16l1  autophagy related 16-like 1 (S. cerevisiae)  Atg16l1  ATG16 autophagy related 16-like 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Atg16l1  ATG16 autophagy related 16-like 1 (S. cerevisiae)  Atg16l1  autophagy-related 16-like 1 (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Atg16l1  autophagy-related 16-like 1 (yeast)  Atg16l1_predicted  ATG16 autophagy related 16-like 1 (S. cerevisiae) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Atg16l1_predicted  ATG16 autophagy related 16-like 1 (S. cerevisiae) (predicted)  Apg16l_predicted  APG16 autophagy 16-like (S. cerevisiae) (predicted)  Symbol and Name updated 1299863 APPROVED