Etv2 (ETS variant transcription factor 2) - Rat Genome Database

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Pathways
Gene: Etv2 (ETS variant transcription factor 2) Rattus norvegicus
Analyze
Symbol: Etv2
Name: ETS variant transcription factor 2
RGD ID: 1310603
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including cell surface receptor signaling pathway; positive regulation of endothelial cell differentiation; and positive regulation of macromolecule biosynthetic process. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in limb ischemia. Orthologous to human ETV2 (ETS variant transcription factor 2); INTERACTS WITH bisphenol A; Monobutylphthalate; N-methyl-4-phenylpyridinium.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ets related protein 71; ETS translocation variant 2; ets variant 2; ets variant gene 2; Etsrp71; LOC361544
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,017,980 - 95,021,582 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl195,017,687 - 95,021,457 (-)EnsemblGRCr8
mRatBN7.2185,890,562 - 85,894,025 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,890,559 - 85,893,431 (-)EnsemblmRatBN7.2
Rnor_6.0189,091,239 - 89,094,570 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,091,239 - 89,094,530 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,246,861 - 90,250,074 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4185,684,698 - 85,686,914 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,262,333 - 80,264,853 (-)NCBICelera
RGSC_v3.1185,762,809 - 85,765,732 (-)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Adventitial Sca1+ Cells Transduced With ETV2 Are Committed to the Endothelial Fate and Improve Vascular Remodeling After Injury. Le Bras A, etal., Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):232-244. doi: 10.1161/ATVBAHA.117.309853. Epub 2017 Nov 30.
3. Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2. Park C, etal., Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):86-96. doi: 10.1161/ATVBAHA.115.306430. Epub 2015 Nov 19.
4. Etv2- and Fli1-Induced Vascular Progenitor Cells Enhance Functional Recovery in Ischemic Vascular Disease Model-Brief Report. Park SY, etal., Arterioscler Thromb Vasc Biol. 2020 Apr;40(4):e105-e113. doi: 10.1161/ATVBAHA.119.313684. Epub 2020 Feb 20.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Extracellular vesicles of ETV2 transfected fibroblasts stimulate endothelial cells and improve neovascularization in a murine model of hindlimb ischemia. Van Pham P, etal., Cytotechnology. 2017 Oct;69(5):801-814. doi: 10.1007/s10616-017-0095-2. Epub 2017 May 2.
8. ETV-2 activated proliferation of endothelial cells and attenuated acute hindlimb ischemia in mice. Van Pham P, etal., In Vitro Cell Dev Biol Anim. 2017 Aug;53(7):616-625. doi: 10.1007/s11626-017-0151-4. Epub 2017 Apr 19.
Additional References at PubMed
PMID:12087183   PMID:16630543   PMID:18462699  


Genomics

Comparative Map Data
Etv2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,017,980 - 95,021,582 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl195,017,687 - 95,021,457 (-)EnsemblGRCr8
mRatBN7.2185,890,562 - 85,894,025 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,890,559 - 85,893,431 (-)EnsemblmRatBN7.2
Rnor_6.0189,091,239 - 89,094,570 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,091,239 - 89,094,530 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,246,861 - 90,250,074 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4185,684,698 - 85,686,914 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,262,333 - 80,264,853 (-)NCBICelera
RGSC_v3.1185,762,809 - 85,765,732 (-)NCBI
Cytogenetic Map1q21NCBI
ETV2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,641,745 - 35,644,871 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,641,745 - 35,644,871 (+)Ensemblhg38GRCh38
GRCh371936,132,647 - 36,135,773 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,824,487 - 40,827,613 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1932,846,129 - 32,849,256 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,637,910 - 32,641,036 (+)NCBIHuRef
CHM1_11936,134,179 - 36,137,305 (+)NCBICHM1_1
T2T-CHM13v2.01938,186,718 - 38,189,844 (+)NCBIT2T-CHM13v2.0
Etv2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,333,041 - 30,335,934 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,333,041 - 30,335,277 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38730,633,616 - 30,636,509 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,633,616 - 30,635,852 (-)Ensemblmm10GRCm38
MGSCv37731,418,635 - 31,420,871 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36730,342,378 - 30,344,612 (-)NCBIMGSCv36mm8
Celera725,225,816 - 25,227,677 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map718.92NCBI
Etv2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554684,857,595 - 4,860,531 (+)Ensembl
ChiLan1.0NW_0049554684,857,023 - 4,859,926 (+)NCBIChiLan1.0ChiLan1.0
ETV2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,638,278 - 41,641,458 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,621,733 - 43,624,908 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,571,829 - 32,575,083 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,307,864 - 41,311,004 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,307,864 - 41,311,004 (+)EnsemblpanPan2panpan1.1
ETV2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,971,238 - 116,974,831 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,971,365 - 116,985,796 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1116,376,575 - 116,379,674 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01117,574,597 - 117,577,707 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,574,598 - 117,577,031 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,137,602 - 117,140,703 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,761,500 - 116,764,598 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,817,402 - 117,820,510 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Etv2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,971,607 - 10,974,730 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936570671,152 - 673,494 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936570671,152 - 673,768 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ETV2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl645,087,100 - 45,089,626 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1645,085,984 - 45,089,592 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,543,308 - 40,546,424 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ETV2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,552,780 - 30,556,374 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,553,931 - 30,556,355 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660738,348,216 - 8,351,726 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Etv2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247947,984,884 - 7,988,296 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247947,985,662 - 7,989,063 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Etv2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12165,370,575 - 165,372,768 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Etv2
9 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:32
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000031873
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat

Markers in Region
BE102623  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2185,890,596 - 85,890,749 (+)MAPPERmRatBN7.2
Rnor_6.0189,091,275 - 89,091,427NCBIRnor6.0
Rnor_5.0190,246,892 - 90,247,044UniSTSRnor5.0
RGSC_v3.4185,684,733 - 85,684,885UniSTSRGSC3.4
Celera180,262,369 - 80,262,521UniSTS
RH 3.4 Map1851.7UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
2 1 16 41 12 11 10 5 10 1 38 24 1 38 1 38 1 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006223194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006223195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC141526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000031873   ⟹   ENSRNOP00000036461
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,017,687 - 95,020,852 (-)Ensembl
mRatBN7.2 Ensembl185,890,559 - 85,893,431 (-)Ensembl
Rnor_6.0 Ensembl189,091,239 - 89,094,530 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000143716   ⟹   ENSRNOP00000112163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,017,687 - 95,021,457 (-)Ensembl
RefSeq Acc Id: NM_001427588   ⟹   NP_001414517
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,017,994 - 95,021,457 (-)NCBI
RefSeq Acc Id: XM_006228814   ⟹   XP_006228876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,017,982 - 95,021,577 (-)NCBI
mRatBN7.2185,890,562 - 85,894,025 (-)NCBI
Rnor_6.0189,091,239 - 89,094,570 (-)NCBI
Rnor_5.0190,246,861 - 90,250,074 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017590045   ⟹   XP_017445534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,017,982 - 95,021,578 (-)NCBI
mRatBN7.2185,890,562 - 85,894,025 (-)NCBI
Rnor_6.0189,091,239 - 89,094,570 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093958   ⟹   XP_038949886
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,017,980 - 95,021,581 (-)NCBI
mRatBN7.2185,890,562 - 85,894,025 (-)NCBI
RefSeq Acc Id: XM_039093960   ⟹   XP_038949888
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,017,980 - 95,021,582 (-)NCBI
mRatBN7.2185,890,562 - 85,894,025 (-)NCBI
RefSeq Acc Id: XM_039093961   ⟹   XP_038949889
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,017,980 - 95,021,581 (-)NCBI
mRatBN7.2185,890,562 - 85,894,025 (-)NCBI
RefSeq Acc Id: XM_039093962   ⟹   XP_038949890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,017,980 - 95,021,582 (-)NCBI
mRatBN7.2185,890,562 - 85,894,025 (-)NCBI
RefSeq Acc Id: XM_063266487   ⟹   XP_063122557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,017,980 - 95,021,582 (-)NCBI
RefSeq Acc Id: XM_063266495   ⟹   XP_063122565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,017,982 - 95,021,577 (-)NCBI
RefSeq Acc Id: XP_006228876   ⟸   XM_006228814
- Peptide Label: isoform X2
- UniProtKB: D3ZEY9 (UniProtKB/TrEMBL),   A6JA05 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017445534   ⟸   XM_017590045
- Peptide Label: isoform X3
- UniProtKB: A6JA05 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000036461   ⟸   ENSRNOT00000031873
RefSeq Acc Id: XP_038949889   ⟸   XM_039093961
- Peptide Label: isoform X1
- UniProtKB: A6JA05 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949890   ⟸   XM_039093962
- Peptide Label: isoform X1
- UniProtKB: A6JA05 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949886   ⟸   XM_039093958
- Peptide Label: isoform X1
- UniProtKB: A6JA05 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949888   ⟸   XM_039093960
- Peptide Label: isoform X1
- UniProtKB: A6JA05 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122557   ⟸   XM_063266487
- Peptide Label: isoform X1
- UniProtKB: A6JA05 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122565   ⟸   XM_063266495
- Peptide Label: isoform X2
- UniProtKB: D3ZEY9 (UniProtKB/TrEMBL),   A6JA05 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414517   ⟸   NM_001427588
- UniProtKB: A6JA05 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000112163   ⟸   ENSRNOT00000143716
Protein Domains
ETS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZEY9-F1-model_v2 AlphaFold D3ZEY9 1-336 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310603 AgrOrtholog
BioCyc Gene G2FUF-60088 BioCyc
Ensembl Genes ENSRNOG00000024288 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000031873 ENTREZGENE
  ENSRNOT00000031873.8 UniProtKB/TrEMBL
  ENSRNOT00000143716 ENTREZGENE
  ENSRNOT00000143716.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro Ets UniProtKB/TrEMBL
  ETS_fam UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:361544 UniProtKB/TrEMBL
NCBI Gene 361544 ENTREZGENE
PANTHER ETS TRANSLOCATION VARIANT 2 UniProtKB/TrEMBL
  PTHR11849 UniProtKB/TrEMBL
Pfam Ets UniProtKB/TrEMBL
PhenoGen Etv2 PhenoGen
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024288 RatGTEx
SMART ETS UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0ABK0M4R4_RAT UniProtKB/TrEMBL
  A6JA05 ENTREZGENE, UniProtKB/TrEMBL
  D3ZEY9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-20 Etv2  ETS variant transcription factor 2  Etv2  ets variant 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Etv2  ets variant 2  Etv2  ets variant gene 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Etv2  ets variant gene 2  Etsrp71_predicted  ets related protein 71 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Etsrp71_predicted  ets related protein 71 (predicted)      Symbol and Name status set to approved 70820 APPROVED