Bop1 (BOP1 ribosomal biogenesis factor) - Rat Genome Database

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Gene: Bop1 (BOP1 ribosomal biogenesis factor) Rattus norvegicus
Analyze
Symbol: Bop1
Name: BOP1 ribosomal biogenesis factor
RGD ID: 1310589
Description: Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in several processes, including regulation of cell cycle; regulation of signal transduction by p53 class mediator; and ribosomal large subunit biogenesis. Predicted to act upstream of or within rRNA processing and ribosomal large subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of PeBoW complex and preribosome, large subunit precursor. Orthologous to human BOP1 (BOP1 ribosomal biogenesis factor); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: block of proliferation 1; block of proliferation 1 protein; LOC300050; MGC109114; ribosome biogenesis protein BOP1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,052,716 - 110,076,529 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7110,052,720 - 110,076,529 (-)EnsemblGRCr8
mRatBN7.27108,172,062 - 108,195,875 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,172,066 - 108,195,931 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7109,916,459 - 109,940,262 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,140,156 - 112,163,959 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,098,544 - 112,122,309 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,514,529 - 117,538,342 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,514,533 - 117,538,342 (-)Ensemblrn6Rnor6.0
Rnor_5.07117,502,160 - 117,525,973 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47114,500,155 - 114,524,030 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7104,523,713 - 104,547,502 (-)NCBICelera
RGSC_v3.17114,534,386 - 114,558,260 (-)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
cylindrospermopsin  (ISO)
D-glucose  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
diquat  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
glafenine  (EXP)
glucose  (ISO)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
monosodium L-glutamate  (ISO)
N-ethyl-N-nitrosourea  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
nitrates  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercetin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
T-2 toxin  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
Theaflavin 3,3'-digallate  (ISO)
thioacetamide  (EXP)
topotecan  (ISO)
Triptolide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IEA,ISO)
nucleolus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)
PeBoW complex  (IBA,IEA,ISO,ISS)
preribosome, large subunit precursor  (IBA,IEA)
ribonucleoprotein complex  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. An overview of pre-ribosomal RNA processing in eukaryotes. Henras AK, etal., Wiley Interdiscip Rev RNA. 2015 Mar-Apr;6(2):225-42. doi: 10.1002/wrna.1269. Epub 2014 Oct 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing. Sloan KE, etal., J Cell Biol. 2013 Mar 4;200(5):577-88. doi: 10.1083/jcb.201207131. Epub 2013 Feb 25.
Additional References at PubMed
PMID:10891491   PMID:12477932   PMID:15225545   PMID:16043514   PMID:16738141   PMID:17353269   PMID:18809582   PMID:22658674   PMID:24120868  


Genomics

Comparative Map Data
Bop1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,052,716 - 110,076,529 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7110,052,720 - 110,076,529 (-)EnsemblGRCr8
mRatBN7.27108,172,062 - 108,195,875 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,172,066 - 108,195,931 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7109,916,459 - 109,940,262 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,140,156 - 112,163,959 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,098,544 - 112,122,309 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,514,529 - 117,538,342 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,514,533 - 117,538,342 (-)Ensemblrn6Rnor6.0
Rnor_5.07117,502,160 - 117,525,973 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47114,500,155 - 114,524,030 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7104,523,713 - 104,547,502 (-)NCBICelera
RGSC_v3.17114,534,386 - 114,558,260 (-)NCBI
Cytogenetic Map7q34NCBI
BOP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,262,045 - 144,291,438 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,262,045 - 144,291,438 (-)Ensemblhg38GRCh38
GRCh378145,316,948 - 145,331,185 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,456,864 - 145,485,928 (-)NCBIBuild 36Build 36hg18NCBI36
Build 348145,456,863 - 145,485,928NCBI
Celera8141,660,871 - 141,689,893 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,600,632 - 140,629,634 (-)NCBIHuRef
CHM1_18145,538,487 - 145,553,302 (-)NCBICHM1_1
T2T-CHM13v2.08145,430,815 - 145,459,890 (-)NCBIT2T-CHM13v2.0
Bop1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,337,188 - 76,361,449 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,337,189 - 76,361,477 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381576,452,988 - 76,477,249 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,452,989 - 76,477,277 (-)Ensemblmm10GRCm38
MGSCv371576,283,426 - 76,307,699 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361576,280,251 - 76,304,524 (-)NCBIMGSCv36mm8
Celera1577,953,429 - 77,977,780 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.91NCBI
Bop1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,882,755 - 2,907,081 (-)Ensembl
ChiLan1.0NW_0049554542,882,694 - 2,907,177 (-)NCBIChiLan1.0ChiLan1.0
BOP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,747,719 - 161,778,596 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18137,277,841 - 137,308,511 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08141,024,518 - 141,055,173 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18144,015,518 - 144,043,278 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8144,015,601 - 144,043,280 (-)EnsemblpanPan2panpan1.1
BOP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,698,635 - 37,723,803 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,698,698 - 37,724,457 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1337,662,427 - 37,688,100 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01338,174,993 - 38,200,746 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,174,997 - 38,199,877 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,847,179 - 37,871,825 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,975,815 - 38,001,527 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,452,110 - 38,477,850 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Bop1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303524,835 - 551,088 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364707,950,982 - 7,977,540 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364707,950,952 - 7,977,186 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BOP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4475,426 - 507,138 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.14486,562 - 507,141 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24681,204 - 684,059 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BOP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,473,377 - 138,503,715 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,473,441 - 138,503,661 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660391,360,979 - 1,392,558 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bop1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,562,997 - 12,585,971 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473512,562,734 - 12,586,544 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Bop1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11248,785,215 - 248,809,059 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Bop1
118 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:117
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000025134
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
1331723Bw25Body weight QTL 253.348body mass (VT:0001259)body weight (CMO:0000012)796700404111672180Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
AI176339  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,172,034 - 108,172,143 (+)MAPPERmRatBN7.2
Rnor_6.07117,514,502 - 117,514,610NCBIRnor6.0
Rnor_5.07117,502,133 - 117,502,241UniSTSRnor5.0
RGSC_v3.47114,500,128 - 114,500,236UniSTSRGSC3.4
Celera7104,523,686 - 104,523,794UniSTS
RH 3.4 Map7791.4UniSTS
Cytogenetic Map7q34UniSTS
AI169617  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,172,162 - 108,172,364 (+)MAPPERmRatBN7.2
Rnor_6.07117,514,630 - 117,514,831NCBIRnor6.0
Rnor_5.07117,502,261 - 117,502,462UniSTSRnor5.0
RGSC_v3.47114,500,256 - 114,500,457UniSTSRGSC3.4
Celera7104,523,814 - 104,524,015UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000025134   ⟹   ENSRNOP00000025133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7110,052,720 - 110,076,529 (-)Ensembl
mRatBN7.2 Ensembl7108,172,103 - 108,195,931 (-)Ensembl
Rnor_6.0 Ensembl7117,514,533 - 117,538,342 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104795   ⟹   ENSRNOP00000094411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,172,066 - 108,194,018 (-)Ensembl
RefSeq Acc Id: NM_001024250   ⟹   NP_001019421
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,052,716 - 110,076,529 (-)NCBI
mRatBN7.27108,172,062 - 108,195,875 (-)NCBI
Rnor_6.07117,514,529 - 117,538,342 (-)NCBI
Rnor_5.07117,502,160 - 117,525,973 (-)NCBI
RGSC_v3.47114,500,155 - 114,524,030 (-)RGD
Celera7104,523,713 - 104,547,502 (-)RGD
Sequence:
RefSeq Acc Id: XM_063263311   ⟹   XP_063119381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,052,757 - 110,068,307 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001019421 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119381 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH92594 (Get FASTA)   NCBI Sequence Viewer  
  EDM15973 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025133
  ENSRNOP00000025133.5
GenBank Protein Q562C2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001019421   ⟸   NM_001024250
- UniProtKB: Q562C2 (UniProtKB/Swiss-Prot),   A6HS98 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025133   ⟸   ENSRNOT00000025134
Ensembl Acc Id: ENSRNOP00000094411   ⟸   ENSRNOT00000104795
RefSeq Acc Id: XP_063119381   ⟸   XM_063263311
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GL60 (UniProtKB/TrEMBL)
Protein Domains
BOP1 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q562C2-F1-model_v2 AlphaFold Q562C2 1-731 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695424
Promoter ID:EPDNEW_R5947
Type:initiation region
Name:Bop1_1
Description:block of proliferation 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07117,538,362 - 117,538,422EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310589 AgrOrtholog
BioCyc Gene G2FUF-32928 BioCyc
Ensembl Genes ENSRNOG00000021773 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025134 ENTREZGENE
  ENSRNOT00000025134.6 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7380064 IMAGE-MGC_LOAD
InterPro BOP1/Erb1 UniProtKB/Swiss-Prot
  BOP1_N_dom UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_CS UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:300050 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109114 IMAGE-MGC_LOAD
NCBI Gene 300050 ENTREZGENE
PANTHER PTHR17605 UniProtKB/Swiss-Prot
  RIBOSOME BIOGENESIS PROTEIN BOP1 UniProtKB/Swiss-Prot
Pfam BOP1NT UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
PhenoGen Bop1 PhenoGen
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000021773 RatGTEx
SMART BOP1NT UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A8I6GL60 ENTREZGENE
  A6HS98 ENTREZGENE, UniProtKB/TrEMBL
  BOP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-09 Bop1  BOP1 ribosomal biogenesis factor  Bop1  block of proliferation 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Bop1  block of proliferation 1  Bop1_predicted  block of proliferation 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Bop1_predicted  block of proliferation 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED