Advanced Search (OLGA)

Gene: Rhoj (ras homolog family member J) Rattus norvegicus

Analyze

Symbol:

Rhoj

Name:

ras homolog family member J

RGD ID:

1310528

Description:

Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin filament organization; positive regulation of cell migration involved in sprouting angiogenesis; and regulation of sprouting angiogenesis. Predicted to act upstream of or within several processes, including Rho protein signal transduction; regulation of cell shape; and retina vasculature morphogenesis in camera-type eye. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human RHOJ (ras homolog family member J); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3,3',5,5'-tetrabromobisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC299145; MGC106003; ras homolog gene family, member J; rho-related GTP-binding protein RhoJ; TC10-like Rho GTPase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RHOJ (ras homolog family member J)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rhoj (ras homolog family member J)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rhoj (ras homolog family member J)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RHOJ (ras homolog family member J)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RHOJ (ras homolog family member J)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rhoj (ras homolog family member J)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RHOJ (ras homolog family member J)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RHOJ (ras homolog family member J)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rhoj (ras homolog family member J)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rhoj (ras homolog family member J)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CTSD (cathepsin D)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RHOJ (ras homolog family member J)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rhoj (ras homolog family member J)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rhoj (ras homolog family member J)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rhoj	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	rhoj	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	99,771,104 - 99,853,366 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	99,771,252 - 99,853,999 (+)	Ensembl				GRCr8
mRatBN7.2	6	94,035,307 - 94,117,642 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	94,035,483 - 94,118,275 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	94,433,053 - 94,514,759 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	94,731,575 - 94,813,279 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	94,160,435 - 94,242,141 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	98,284,361 - 98,367,122 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	98,284,170 - 98,367,756 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	107,702,937 - 107,785,252 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	97,911,744 - 97,995,878 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	92,465,594 - 92,546,315 (+)	NCBI		Celera
RGSC_v3.1	6	97,915,199 - 97,999,311 (+)	NCBI
Cytogenetic Map	6	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cardiomyopathy (ISO)

Colonic Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

CGP 52608 (ISO)

choline (ISO)

cobalt dichloride (ISO)

corticosterone (EXP)

dexamethasone (ISO)

dextran sulfate (ISO)

dibutyl phthalate (EXP)

diclofenac (ISO)

dimethylarsinic acid (EXP)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethylparaben (ISO)

folic acid (ISO)

formaldehyde (ISO)

furan (EXP)

gentamycin (EXP)

inulin (ISO)

isoprenaline (ISO)

L-methionine (ISO)

methotrexate (ISO)

methoxychlor (EXP)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

nitrates (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

PhIP (EXP)

resveratrol (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

Soman (EXP)

temozolomide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

triptonide (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vanadyl sulfate (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (IEA,ISO)

actin filament organization (IBA)

endocytosis (IBA)

establishment of cell polarity (IBA)

positive regulation of cell migration involved in sprouting angiogenesis (IEA,ISO)

regulation of cell shape (IEA,ISO)

regulation of endothelial cell migration (IEA,ISO)

regulation of sprouting angiogenesis (IEA,ISO)

retina vasculature morphogenesis in camera-type eye (ISO)

Rho protein signal transduction (ISO)

signal transduction (IBA)

small GTPase-mediated signal transduction (IEA)

Cellular Component

plasma membrane (IBA,IEA,ISO)

Molecular Function

GTP binding (IBA,IEA,ISO)

GTPase activity (IBA,IEA,ISO)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase binding (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10967094	PMID:12477932	PMID:18388891	PMID:21628409	PMID:22535667	PMID:23533145	PMID:27660391	PMID:28727754	PMID:30158707

Genomics

Comparative Map Data

Rhoj
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	99,771,104 - 99,853,366 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	99,771,252 - 99,853,999 (+)	Ensembl				GRCr8
mRatBN7.2	6	94,035,307 - 94,117,642 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	94,035,483 - 94,118,275 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	94,433,053 - 94,514,759 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	94,731,575 - 94,813,279 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	94,160,435 - 94,242,141 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	98,284,361 - 98,367,122 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	98,284,170 - 98,367,756 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	107,702,937 - 107,785,252 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	97,911,744 - 97,995,878 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	92,465,594 - 92,546,315 (+)	NCBI		Celera
RGSC_v3.1	6	97,915,199 - 97,999,311 (+)	NCBI
Cytogenetic Map	6	q24	NCBI

RHOJ
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	63,204,443 - 63,293,508 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	63,204,114 - 63,293,508 (+)	Ensembl			hg38	GRCh38
GRCh37	14	63,671,161 - 63,760,226 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	62,740,898 - 62,828,312 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	62,740,897 - 62,828,312	NCBI
Celera	14	43,721,815 - 43,809,227 (+)	NCBI		Celera
Cytogenetic Map	14	q23.2	NCBI
HuRef	14	43,837,525 - 43,926,644 (+)	NCBI		HuRef
CHM1_1	14	63,610,149 - 63,699,277 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	57,411,795 - 57,500,853 (+)	NCBI		T2T-CHM13v2.0

Rhoj
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	75,355,087 - 75,448,229 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	75,355,096 - 75,448,230 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	12	75,308,313 - 75,401,455 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	75,308,322 - 75,401,456 (+)	Ensembl			mm10	GRCm38
MGSCv37	12	76,409,300 - 76,502,442 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	12	76,227,153 - 76,320,295 (+)	NCBI		MGSCv36	mm8
Celera	12	76,399,403 - 76,485,627 (+)	NCBI		Celera
Cytogenetic Map	12	C3	NCBI
cM Map	12	32.63	NCBI

Rhoj
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955466	6,476,822 - 6,564,988 (-)	Ensembl
ChiLan1.0	NW_004955466	6,476,822 - 6,564,890 (-)	NCBI	ChiLan1.0	ChiLan1.0

RHOJ
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	64,312,926 - 64,401,985 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	63,529,470 - 63,618,501 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	43,783,185 - 43,872,000 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	62,039,436 - 62,126,908 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	62,039,418 - 62,126,908 (+)	Ensembl			panPan2	panpan1.1

RHOJ
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	37,803,460 - 37,880,411 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	37,803,717 - 37,882,207 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	37,560,607 - 37,637,620 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	38,030,147 - 38,108,957 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	38,030,239 - 38,108,013 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	37,647,128 - 37,724,061 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	37,726,711 - 37,803,608 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	38,079,926 - 38,156,853 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rhoj
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	67,013,327 - 67,097,318 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936495	7,094,513 - 7,174,371 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936495	7,094,522 - 7,174,371 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RHOJ
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	194,760,939 - 194,844,356 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	194,761,588 - 194,843,867 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	216,775,655 - 216,796,767 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RHOJ
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	40,352,967 - 40,458,993 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	40,353,075 - 40,459,484 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666053	28,578,164 - 28,680,770 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rhoj
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	37,736,256 - 37,832,008 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624734	37,720,834 - 37,831,907 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rhoj
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	89,480,783 - 89,565,994 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	439
Count of miRNA genes:	208
Interacting mature miRNAs:	243
Transcripts:	ENSRNOT00000031979
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	71278722	116278722	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	64367996	109367996	Rat
2293088	Iddm28	Insulin dependent diabetes mellitus QTL 28	5.21		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	68767270	135411972	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	88019181	136741135	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	93560258	136550638	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	90871046	135871046	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	98944780	143944780	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	79198463	144254945	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	46050607	116278722	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	93778632	138778632	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2293837	Kiddil1	Kidney dilation QTL 1	3.7		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
2293842	Kiddil3	Kidney dilation QTL 3	4.3		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	84490437	129490437	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	90871046	135871046	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	93560258	136550638	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	78204640	123204640	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	93560258	136550638	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	76937178	121937178	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	99437079	125323237	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	86494122	112380234	Rat
1331722	Thshl1	Thyroid stimulating hormone level QTL 1	11.7	0.0001	blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	6	99708426	112483760	Rat

Markers in Region

BI284631

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	6	99,852,555 - 99,852,728 (+)	Marker Load Pipeline
mRatBN7.2	6	94,116,830 - 94,117,004 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	98,366,311 - 98,366,484	NCBI	Rnor6.0
Rnor_5.0	6	107,784,441 - 107,784,614	UniSTS	Rnor5.0
RGSC_v3.4	6	97,995,067 - 97,995,240	UniSTS	RGSC3.4
Celera	6	92,545,504 - 92,545,677	UniSTS
RH 3.4 Map	6	668.8	UniSTS
Cytogenetic Map	6	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	160	91	90	59	31	59	6	293	131	11	139	79	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001008320	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC086525	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000031979 ⟹ ENSRNOP00000030536

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	99,771,252 - 99,853,999 (+)	Ensembl
mRatBN7.2 Ensembl	6	94,035,752 - 94,118,275 (+)	Ensembl
Rnor_6.0 Ensembl	6	98,284,170 - 98,367,756 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099066 ⟹ ENSRNOP00000095177

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	99,771,252 - 99,845,636 (+)	Ensembl
mRatBN7.2 Ensembl	6	94,035,483 - 94,109,912 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110727 ⟹ ENSRNOP00000081847

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	99,771,294 - 99,853,999 (+)	Ensembl
mRatBN7.2 Ensembl	6	94,035,563 - 94,118,275 (+)	Ensembl

RefSeq Acc Id:

NM_001008320 ⟹ NP_001008321

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	99,771,383 - 99,853,366 (+)	NCBI
mRatBN7.2	6	94,035,652 - 94,117,642 (+)	NCBI
Rnor_6.0	6	98,284,361 - 98,367,122 (+)	NCBI
Rnor_5.0	6	107,702,937 - 107,785,252 (+)	NCBI
RGSC_v3.4	6	97,911,744 - 97,995,878 (+)	RGD
Celera	6	92,465,594 - 92,546,315 (+)	RGD

Sequence:

show sequence

ACGAGAGTTCCTCAACTCCAGCTCTACTCCAACTCCTCTTCTCCGTTGGGATTGGGAGAAAGGA
ACGGACCCTTTTCATCCCTCCTCCCAAGAGTGCGTTGCCTTTCTTCTGCAGCATGGTGAGCGGC
GGGGCTCGCGTGTGTCTGGGCTGTGCCTGGGAGAGCCGGGCCAGCCACAGTCAGGCCGCCTGAG
CTCCAGCCCCGGGCCCGTGCCACCGCTCCATGCACTACAGAAGCCCCAGCAGCTGCTGCGGGAG
CCACCAACATGAGCTGCAGAGAGGGGACTGACAGCAGCTGCGGCTGCGGTGGGCGCGATGAAAA
CAGGATCCTGAAGTGCGTGGTGGTCGGGGACGGCGCGGTGGGGAAGACTTGCCTGCTGATGAGC
TACGCCAACGACGCCTTCCCGGAGGAATACGTGCCCACTGTGTTTGACCACTACGCAGTTACCG
TGACAGTGGGAGGCAAGCAGCACCTGCTTGGACTGTACGACACCGCGGGACAGGAGGACTACAA
CCAGCTGCGGCCCCTCTCTTACCCCAACACCGACGTGTTTCTCATCTGCTTCTCTGTCGTGAAC
CCTGCCTCTTACCACAACGTTCAGGAGGAGTGGGTCCCGGAGCTGAAGGACTGCATGCCTCACG
TGCCTTACGTGCTCATTGGGACCCAGATTGATCTCCGAGATGACCCCAAAACCTTGGCGCGTCT
GCTGTACATGAAGGAGAAGCCCCTCACCTATGAGCACGGCGTGAAACTGGCGAAAGCGATAGGA
GCTCAGTGCTACTTGGAATGCTCTGCCCTGACTCAGAAGGGTCTCAAAGCTGTTTTTGATGAAG
CCATCCTCACCATTTTCCACCCCAAGAAAAAAAAGAAAGGCTGCCACGGCTGCTGTGTAATCAT
CTGAAGTTGCCTGAGACCCGTCTCTCCGCCATGCAAAGAGGGAAGCCAGTCTCTGAGAACCAAC
GCTAGCCGAAAGGAGGGCGTGACCAGAAAGGAATTCCTGCATCCTCAAAGCCTGTCCCCACACC
CTGCCAATTCCCCAGCTCAGTATCCTGTAAGCCACTGCCACAGCCCCAAGCCAGCCAGACATCC
ACACTGCGCATGGAGAAAGCAGAGGCTCGTTCAAACCGCAGGCTGGCGAGGTGTTGGAAGCCGA
GTGAAGATCCGTCCAGTATTTCACATCTTCTCTCTCACGGTTATGAACCAACCGGAAGTCATGA
CGGGCAAACCAAGTACTCTCTGTCCTGAACCAATGGCCTTAGTTCATGTCTTCACCAACCTTGG
GAATACGACAACTTTTTTTTTTCTGAGTCTTTTACTCAAGCCCCTTGCCGTTCATTTATTTCTA
CTGCAGTTTCCTGTTGTCCAATCACTTGAGCCTTACAAATCCACATCAAAATAACCGAAAGACA
AGCTGGATTGTGTTTATGCCAACTGACAGTGGCTCTCTGCCAATGTTCTTAGAGCTGCCATGTA
CCTCTGAATGCCTAATTACAAAAAAAAAATTACAACTTTTATAAACTGACAGACCCATAATGTT
TTTAACCTTTTTAAAAGAAAGCATCCTGTGAATTATTACAGCTCCCCGAGTTTGGCCAAAGATC
AACCTACAAATGCTGCAGGTGATAGGGGGTCTGCTCTTGCAAAGCCTTACTGTCATTCAAAAAC
GGACTGTCGTGGAAGAAACCGTTTTCTACTCCTCCTCTAAACTGGTCAGGACAATAATAGAGCA
AAGCTATCTTCCCACTGCAGGAGAGTGAGCCTGACCCACCCTGTTCATGTAGTATCTTCACTTT
TTCTCCTGTGCCCACTGTGTTCCCAGTCAAAGCTTGCCAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039112008 ⟹ XP_038967936

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	99,771,104 - 99,852,370 (+)	NCBI
mRatBN7.2	6	94,035,307 - 94,116,676 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001008321	(Get FASTA)	NCBI Sequence Viewer
	XP_038967936	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86525	(Get FASTA)	NCBI Sequence Viewer
	EDM03632	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030536
	ENSRNOP00000030536.3
	ENSRNOP00000081847.1
	ENSRNOP00000095177
	ENSRNOP00000095177.1

RefSeq Acc Id:

NP_001008321 ⟸ NM_001008320

- UniProtKB:

Q5RJS2 (UniProtKB/TrEMBL), A0A8I5ZTS1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSCREGTDSSCGCGGRDENRILKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTV
GGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPY
VLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAIL
TIFHPKKKKKGCHGCCVII

hide sequence

Ensembl Acc Id:

ENSRNOP00000030536 ⟸ ENSRNOT00000031979

RefSeq Acc Id:	XP_038967936 ⟸ XM_039112008
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AJ60 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000081847 ⟸ ENSRNOT00000110727

Ensembl Acc Id:

ENSRNOP00000095177 ⟸ ENSRNOT00000099066

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5RJS2-F1-model_v2	AlphaFold	Q5RJS2	1-211	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694671

Promoter ID:

EPDNEW_R5193

Type:

multiple initiation site

Name:

Rhoj_1

Description:

ras homolog family member J

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R5194

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	98,284,234 - 98,284,294	EPDNEW

RGD ID:

13694670

Promoter ID:

EPDNEW_R5194

Type:

multiple initiation site

Name:

Rhoj_2

Description:

ras homolog family member J

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R5193

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	98,284,461 - 98,284,521	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310528	AgrOrtholog
BioCyc Gene	G2FUF-37083	BioCyc
Ensembl Genes	ENSRNOG00000021919	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000031979	ENTREZGENE
	ENSRNOT00000031979.6	UniProtKB/TrEMBL
	ENSRNOT00000099066	ENTREZGENE
	ENSRNOT00000099066.2	UniProtKB/TrEMBL
	ENSRNOT00000110727.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7303905	IMAGE-MGC_LOAD
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Ras_GTPase	UniProtKB/TrEMBL
	Small_GTP_bd	UniProtKB/TrEMBL
	Small_GTPase_Rho	UniProtKB/TrEMBL
KEGG Report	rno:299145	UniProtKB/TrEMBL
MGC_CLONE	MGC:106003	IMAGE-MGC_LOAD
NCBI Gene	299145	ENTREZGENE
PANTHER	PTHR24072	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PhenoGen	Rhoj	PhenoGen
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000021919	RatGTEx
SMART	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8I5ZTS1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AJ60	ENTREZGENE, UniProtKB/TrEMBL
	A6HC77_RAT	UniProtKB/TrEMBL
	Q5RJS2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-15	Rhoj	ras homolog family member J	Rhoj	ras homolog gene family, member J	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Rhoj	ras homolog gene family, member J	Rhoj_predicted	ras homolog gene family, member J (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Rhoj_predicted	ras homolog gene family, member J (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - CTD