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Gene: Sugp1 (SURP and G patch domain containing 1) Rattus norvegicus

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Symbol:

Sugp1

Name:

SURP and G patch domain containing 1

RGD ID:

1310496

Description:

Predicted to enable mRNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Predicted to be active in nucleoplasm. Orthologous to human SUGP1 (SURP and G-patch domain containing 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC290666; Sf4; splicing factor 4; SURP and G-patch domain-containing protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SUGP1 (SURP and G-patch domain containing 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Sugp1 (SURP and G patch domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sugp1 (SURP and G-patch domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SUGP1 (SURP and G-patch domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SUGP1 (SURP and G-patch domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sugp1 (SURP and G-patch domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SUGP1 (SURP and G-patch domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SUGP1 (SURP and G-patch domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sugp1 (SURP and G-patch domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Sugp1 (SURP and G-patch domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RPL5 (ribosomal protein L5)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SUGP1 (SURP and G-patch domain containing 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SUGP1 (SURP and G-patch domain containing 1)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sugp1 (SURP and G patch domain containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sugp1 (SURP and G patch domain containing 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sugp1 (SURP and G patch domain containing 1)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Danio rerio (zebrafish):	sugp1 (SURP and G patch domain containing 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG31550	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG31550	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sugp1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sugp1	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)

Allele / Splice:

Sf4^{Tn(sb-T2/Bart3)2.264Mcwi}

Genetic Models:

F344-Sf4^{Tn(sb-T2/Bart3)2.264Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	19,386,588 - 19,417,460 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	19,386,589 - 19,417,460 (-)	Ensembl				GRCr8
mRatBN7.2	16	19,352,659 - 19,383,533 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	19,351,793 - 19,383,756 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	19,392,601 - 19,423,733 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	20,524,523 - 20,555,456 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	19,445,574 - 19,476,707 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	21,100,923 - 21,131,795 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	21,100,924 - 21,131,795 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	21,016,310 - 21,047,301 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	16	20,950,430 - 20,985,149 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	19,835,921 - 19,866,795 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	19,541,347 - 19,572,611 (-)	NCBI		Celera
RGSC_v3.1	16	19,835,919 - 19,866,793 (-)	NCBI
Cytogenetic Map	16	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

aristolochic acid A (ISO)

atrazine (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

casticin (ISO)

chlorpyrifos (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

diquat (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (ISO)

flutamide (EXP)

FR900359 (ISO)

fulvestrant (ISO)

hexane (EXP)

hydrogen peroxide (ISO)

iron dichloride (ISO)

lead(0) (ISO)

leflunomide (ISO)

methapyrilene (ISO)

methidathion (ISO)

methoxychlor (EXP)

paracetamol (ISO)

PCB138 (EXP)

perfluorohexanesulfonic acid (ISO)

quercitrin (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

temozolomide (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

mRNA processing (IEA)

RNA processing (IEA)

RNA splicing (IEA)

Cellular Component

nucleoplasm (IBA)

nucleus (IEA)

spliceosomal complex (IEA)

Molecular Function

mRNA binding (IEA,ISO)

nucleic acid binding (IEA)

protein binding (ISO)

RNA binding (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:22681889

Genomics

Comparative Map Data

Sugp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	19,386,588 - 19,417,460 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	19,386,589 - 19,417,460 (-)	Ensembl				GRCr8
mRatBN7.2	16	19,352,659 - 19,383,533 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	19,351,793 - 19,383,756 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	19,392,601 - 19,423,733 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	20,524,523 - 20,555,456 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	19,445,574 - 19,476,707 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	21,100,923 - 21,131,795 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	21,100,924 - 21,131,795 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	21,016,310 - 21,047,301 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	16	20,950,430 - 20,985,149 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	19,835,921 - 19,866,795 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	19,541,347 - 19,572,611 (-)	NCBI		Celera
RGSC_v3.1	16	19,835,919 - 19,866,793 (-)	NCBI
Cytogenetic Map	16	p14	NCBI

SUGP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	19,276,033 - 19,320,509 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	19,276,018 - 19,320,511 (-)	Ensembl			hg38	GRCh38
GRCh37	19	19,386,842 - 19,431,318 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	19,248,322 - 19,292,307 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	19,291,389 - 19,335,381 (-)	NCBI		Celera
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	18,951,058 - 18,994,630 (-)	NCBI		HuRef
CHM1_1	19	19,388,088 - 19,432,088 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	19,413,485 - 19,457,965 (-)	NCBI		T2T-CHM13v2.0

Sugp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	70,495,435 - 70,524,997 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	70,495,463 - 70,524,997 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	70,042,769 - 70,072,347 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	70,042,813 - 70,072,347 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	72,566,712 - 72,595,852 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	72,971,802 - 73,000,942 (+)	NCBI		MGSCv36	mm8
Celera	8	72,603,099 - 72,632,001 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.15	NCBI

Sugp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	2,563,263 - 2,584,834 (+)	Ensembl
ChiLan1.0	NW_004955524	2,563,299 - 2,584,046 (+)	NCBI	ChiLan1.0	ChiLan1.0

SUGP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	24,139,305 - 24,183,224 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	23,145,589 - 23,202,487 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	18,715,215 - 18,758,712 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	19,718,310 - 19,762,402 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	19,718,310 - 19,762,402 (-)	Ensembl			panPan2	panpan1.1

SUGP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	43,891,572 - 43,922,991 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	43,891,750 - 43,922,986 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	43,808,689 - 43,840,117 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	44,379,426 - 44,410,890 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	44,379,614 - 44,410,886 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	43,616,943 - 43,648,396 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	44,026,542 - 44,058,007 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	44,301,796 - 44,333,296 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Sugp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	202,583,859 - 202,614,903 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936596	2,133,268 - 2,164,228 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936596	2,133,090 - 2,164,042 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SUGP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	58,574,540 - 58,615,448 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	58,574,434 - 58,615,054 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SUGP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	17,743,065 - 17,784,325 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	17,743,388 - 17,784,126 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666074	1,522,379 - 1,564,826 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sugp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624908	2,145,412 - 2,165,088 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624908	2,145,644 - 2,165,066 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Sugp1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	12,310,041 - 12,338,369 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Sugp1
61 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	39
Count of miRNA genes:	37
Interacting mature miRNAs:	38
Transcripts:	ENSRNOT00000027826
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1549842	Bp248	Blood pressure QTL 248		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	387123	45387123	Rat
2307172	Activ4	Activity QTL 4	3.71	0.00023	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	1	33425095	Rat
1354584	Despr6	Despair related QTL 6	3.1	0.0067	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	39568015	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4234212	53708481	Rat
631517	Scl9	Serum cholesterol level QTL 9	3.3		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	16	15748006	25801629	Rat
1354625	Despr7	Despair related QTL 7	3.16	0.016	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	4744222	49744222	Rat
61405	Niddm6	Non-insulin dependent diabetes mellitus QTL 6	3.66	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	16	1	26734272	Rat
631830	Alc7	Alcohol consumption QTL 7	2.9		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	1	26734272	Rat
7411664	Foco30	Food consumption QTL 30	11	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	4354822	49354822	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	387123	45387123	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	4234212	49757901	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
1600369	Hcas8	Hepatocarcinoma susceptibility QTL 8			liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	16	16278184	27244292	Rat
2303566	Bw90	Body weight QTL 90	2		body mass (VT:0001259)	body weight (CMO:0000012)	16	1	39568015	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2306902	Bp339	Blood pressure QTL 339		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	3386790	49757901	Rat
1300133	Rf24	Renal function QTL 24	3.64		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	16	3386790	26128267	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
634355	Rends4	Renal damage susceptibility QTL 4		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	16	1	26734272	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17730818	72536785	Rat
2293343	Glom16	Glomerulus QTL 16	7.4		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	16	839086	52786090	Rat
2301406	Kidm39	Kidney mass QTL 39		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	16	15905802	60905802	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat
6903319	Bw114	Body weight QTL 114	2.7	0.0037	body mass (VT:0001259)	body weight (CMO:0000012)	16	3301683	48301683	Rat

Markers in Region

AW530829

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	16	19,386,653 - 19,386,977 (+)	Marker Load Pipeline
mRatBN7.2	16	19,352,724 - 19,353,048 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	21,100,989 - 21,101,312	NCBI	Rnor6.0
Rnor_5.0	16	21,016,376 - 21,016,699	UniSTS	Rnor5.0
Rnor_5.0	16	20,950,496 - 20,950,819	UniSTS	Rnor5.0
RGSC_v3.4	16	19,835,987 - 19,836,310	UniSTS	RGSC3.4
Celera	16	19,541,413 - 19,541,736	UniSTS
RH 3.4 Map	16	236.6	UniSTS
Cytogenetic Map	16	p14	UniSTS

Genetic Models

This gene Sugp1 is modified in the following models/strains:

F344-Sf4^{Tn(sb-T2/Bart3)2.264Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001011920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC123370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC134063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000078005 ⟹ ENSRNOP00000072874

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	19,386,589 - 19,411,985 (-)	Ensembl
mRatBN7.2 Ensembl	16	19,351,793 - 19,378,058 (-)	Ensembl
Rnor_6.0 Ensembl	16	21,100,924 - 21,131,795 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110921 ⟹ ENSRNOP00000082578

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	19,386,589 - 19,417,460 (-)	Ensembl
mRatBN7.2 Ensembl	16	19,351,793 - 19,383,756 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000137847 ⟹ ENSRNOP00000104081

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	19,386,907 - 19,417,460 (-)	Ensembl

RefSeq Acc Id:

NM_001011920 ⟹ NP_001011920

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	19,386,588 - 19,417,460 (-)	NCBI
mRatBN7.2	16	19,352,659 - 19,383,533 (-)	NCBI
Rnor_6.0	16	21,100,923 - 21,131,795 (-)	NCBI
Rnor_5.0	16	20,950,430 - 20,985,149 (-)	NCBI
RGSC_v3.4	16	19,835,921 - 19,866,795 (-)	RGD
Celera	16	19,541,347 - 19,572,611 (-)	RGD

Sequence:

show sequence

GTGGGATTGGATGAGTCTCAAGATGGACAACCGGGATGTTGCAGGAAAGGCCAATCGGTGGTTC
GGGATGGCACAACCCAAGTCTGGAAAGATGAATATGAACATCCTCCACCAGGAAGAGCTCATTG
CTCAGAAGAAGCGGGAGATTGAGGCCAGAATGGAACAAAAGGCCAGACAGAGTCATGTGGCGAG
TCCACAGCCCCCTCATCCTGGGGAAGTTGCCGATGCACAAAACTCCTGCATCTCCAACAAGTTT
GCCAACGACGGCAGCTTCTTGCAGCAGTTTCTGAAGTTACAGAAGGCACAGGCAAGCACAGATT
CAGCCCCCAGGGCCCCCCCCAGCTCGCCAGCACCCAGCTCCTTGAAGAGACCCCTCCTGCTCAG
CAAGCGAACGGGCCTGGGGCTGGGTAGCCCAATGGGCCCTGTGAAGAACTACTCACATGCCAAA
CAGCTACCTGTCGCACACCGCCCAAGTGTCTTCCAGTCCCCTGATGATGATGACGAGGAGGAGG
ACTATGAGCAGTGGCTGGAAATCAAAGTTTCACCCCCAGAGGGAGCCGAGACTCGGAGAGTGAT
AGAGAAGCTAGCCCGTTTTGTGGCAGAAGGAGGCCCCGAGCTAGAGAAAGTAGCTATGGAGGAC
TACAAGGATAACCCAGCCTTCACGTTTTTACATGATAAGAATAGCAGGGAATTCCTATACTACA
GAAAGAAGGTAGCCGAGATCAGGAAAGAAGCCCAAAAGCCACAGGCAGCCACCCAGAAAGTTTC
ACCCCCAGAGGACGAAGAGGCCAAGAACCTTGCAGAAAAGTTGGCCAGGTTCATAGCAGACGGG
GGTCCTGAAGTGGAGACCATCGCCCTCCAGAACAACCGTGAGAATCAGGCCTTCAGTTTTCTCT
ATGATCCCAACAGCCAAGGGTACAGGTACTACAAGCAAAAGCTGGAGGAGTTCCGGAAAGCCAA
GGCGGGCTCCACAGGCTCCCTTCCTGCTCCTGTTCCCAACCCCAGCCTGCGGCGAAAGTCTGCC
CCAGAAGCCCTGTCAGGGGCTGTGCCCCCCATCACTGCCTGCCCTACTCCAGTGGCCCCAGCAC
CTGCTGTCAACCCCACTCCATCCATCCCCGGGAAGCCCACCGCCACAGCCACTGTAAAGAGGAA
GCGGAAGAGCCGGTGGGGGCCTGAGGAGGACAAAGTGGAGCTGCCACCTGCAGAACTGGCACAG
AAGGACACAGATGCCTCACCTTCACCTCTTTCAGTTCAAGATCTCAAGGGGCTTGGCTATGAGA
AGGGGAAACCTGTGGGCCTGGTGGGTGTCACAGAGTTGTCCGATGCACAAAAGAAGCAGCTAAA
AGAACAGCAGGAGATGCAGCAGATGTATGACATGATTATGCAGCACAAGCGTGCCATGCAAGAC
ATGCAGCTTCTGTGGGAGAAGGCGCTGCAGCAACACCAGCATGGCTATGACAGTGACGAGGAGG
TAGACAGTGAACTGGGCACCTGGGAGCACCAGCTGCGACGCATGGAGATGGACAAGACACGGGA
GTGGGCAGAGCAGCTGACACAGATGGGTCGGGGCAAGCACTTCATCGGAGACTTCCTGCCCCCT
GATGAGCTAGAGAAGTTCATGGAGACCTTCAAGGCCCTGAAGGAGGGCAGAGAGCCAGACTACT
CAGAGTACAAGGAGTTTAAGCTGACAGTGGAAAACATTGGCTACCAGATGCTCATGAAGATGGG
CTGGAAGGAGGGCGAGGGGCTAGGCACTGAGGGCCAGGGCATCAAGAACCCAGTGAACAAGGGT
GCCACCACAATTGATGGAGCTGGCTTTGGCATTGACCGGCCAGCTGAACTCTCAAAGGAGGATG
ATGAGTACGAGGCCTTCCGCAAGAGGATGATGCTGGCCTACCGCTTCCGGCCCAACCCTCTGAA
CAACCCCAGACGGCCCTACTACTGAATATTCTGGAAACACAAAGTCTACTTTCAGATTGGACAT
CCTTGGACTGTGGAATGTTCTGGCATCCATCTCTGCCCTGTTGTCACAAGTGTTGTGCTGTGTA
TTAAAATCCCAATGCTTACCTGCCCAGCAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039094335 ⟹ XP_038950263

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	19,386,588 - 19,417,415 (-)	NCBI
mRatBN7.2	16	19,352,659 - 19,383,493 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001011920	(Get FASTA)	NCBI Sequence Viewer
	XP_038950263	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79341	(Get FASTA)	NCBI Sequence Viewer
	EDL90643	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072874
	ENSRNOP00000082578
	ENSRNOP00000082578.1
GenBank Protein	Q68FU8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001011920 ⟸ NM_001011920

- UniProtKB:

Q68FU8 (UniProtKB/Swiss-Prot), A6KA93 (UniProtKB/TrEMBL), A0A8L2R876 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSLKMDNRDVAGKANRWFGMAQPKSGKMNMNILHQEELIAQKKREIEARMEQKARQSHVASPQP
PHPGEVADAQNSCISNKFANDGSFLQQFLKLQKAQASTDSAPRAPPSSPAPSSLKRPLLLSKRT
GLGLGSPMGPVKNYSHAKQLPVAHRPSVFQSPDDDDEEEDYEQWLEIKVSPPEGAETRRVIEKL
ARFVAEGGPELEKVAMEDYKDNPAFTFLHDKNSREFLYYRKKVAEIRKEAQKPQAATQKVSPPE
DEEAKNLAEKLARFIADGGPEVETIALQNNRENQAFSFLYDPNSQGYRYYKQKLEEFRKAKAGS
TGSLPAPVPNPSLRRKSAPEALSGAVPPITACPTPVAPAPAVNPTPSIPGKPTATATVKRKRKS
RWGPEEDKVELPPAELAQKDTDASPSPLSVQDLKGLGYEKGKPVGLVGVTELSDAQKKQLKEQQ
EMQQMYDMIMQHKRAMQDMQLLWEKALQQHQHGYDSDEEVDSELGTWEHQLRRMEMDKTREWAE
QLTQMGRGKHFIGDFLPPDELEKFMETFKALKEGREPDYSEYKEFKLTVENIGYQMLMKMGWKE
GEGLGTEGQGIKNPVNKGATTIDGAGFGIDRPAELSKEDDEYEAFRKRMMLAYRFRPNPLNNPR
RPYY

hide sequence

Ensembl Acc Id:

ENSRNOP00000072874 ⟸ ENSRNOT00000078005

RefSeq Acc Id:	XP_038950263 ⟸ XM_039094335
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2R876 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000082578 ⟸ ENSRNOT00000110921

Ensembl Acc Id:

ENSRNOP00000104081 ⟸ ENSRNOT00000137847

Protein Domains

G-patch SURP motif

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q68FU8-F1-model_v2	AlphaFold	Q68FU8	1-644	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700047

Promoter ID:

EPDNEW_R10571

Type:

multiple initiation site

Name:

Sugp1_1

Description:

SURP and G patch domain containing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	21,131,787 - 21,131,847	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310496	AgrOrtholog
BioCyc Gene	G2FUF-11751	BioCyc
Ensembl Genes	ENSRNOG00000052111	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000078005	ENTREZGENE
	ENSRNOT00000110921	ENTREZGENE
	ENSRNOT00000110921.1	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.10.790	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7106652	IMAGE-MGC_LOAD
InterPro	G_patch_dom	UniProtKB/Swiss-Prot
	SUGP1/2	UniProtKB/Swiss-Prot
	Surp	UniProtKB/Swiss-Prot
	SWAP/Surp_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:290666	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94785	IMAGE-MGC_LOAD
NCBI Gene	290666	ENTREZGENE
PANTHER	PTHR23340	UniProtKB/Swiss-Prot
	SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 1	UniProtKB/Swiss-Prot
Pfam	G-patch	UniProtKB/Swiss-Prot
	Surp	UniProtKB/Swiss-Prot
PhenoGen	Sugp1	PhenoGen
PROSITE	G_PATCH	UniProtKB/Swiss-Prot
	SURP	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000052111	RatGTEx
SMART	G_patch	UniProtKB/Swiss-Prot
	SWAP	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF109905	UniProtKB/Swiss-Prot
UniProt	A0A8L2R876	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LQ20_RAT	UniProtKB/TrEMBL
	A6KA93	ENTREZGENE, UniProtKB/TrEMBL
	Q68FU8	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Sf4	splicing factor 4	Sf4_predicted	splicing factor 4 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Sf4_predicted	splicing factor 4 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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