Cpap (centrosome assembly and centriole elongation protein) - Rat Genome Database

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Gene: Cpap (centrosome assembly and centriole elongation protein) Rattus norvegicus
Analyze
Symbol: Cpap (Ensembl: Cenpj)
Name: centrosome assembly and centriole elongation protein (Ensembl:centromere protein J)
RGD ID: 1310464
Description: Predicted to enable several functions, including gamma-tubulin binding activity; identical protein binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including cilium assembly; microtubule cytoskeleton organization; and positive regulation of cell cycle process. Predicted to act upstream of or within several processes, including cilium assembly; microtubule cytoskeleton organization; and positive regulation of non-motile cilium assembly. Predicted to be located in ciliary basal body and cytoplasm. Predicted to be part of procentriole replication complex. Predicted to be active in centriole and centrosome. Human ortholog(s) of this gene implicated in Seckel syndrome 4; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 6. Orthologous to human CPAP (centrosome assembly and centriole elongation protein); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cenpj; centromere protein J; LOC305909
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81534,742,838 - 34,806,020 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1534,742,838 - 34,802,421 (-)EnsemblGRCr8
mRatBN7.21530,627,206 - 30,690,384 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1530,627,224 - 30,686,791 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1532,618,561 - 32,678,144 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01533,769,217 - 33,828,800 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01532,027,309 - 32,086,891 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01536,745,672 - 36,809,228 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1536,746,088 - 36,798,814 (-)Ensemblrn6Rnor6.0
Rnor_5.01540,599,733 - 40,658,983 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41535,487,198 - 35,550,034 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1530,339,104 - 30,398,973 (-)NCBICelera
RGSC_v3.11535,503,314 - 35,558,495 (-)NCBI
Cytogenetic Map15p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
alcohol  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
clotrimazole  (EXP)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
flavone  (ISO)
folic acid  (ISO)
FR900359  (ISO)
geldanamycin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
propanal  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centriole  (IBA,IEA,ISO)
centrosome  (IBA,ISO)
ciliary basal body  (ISO)
cytoplasm  (ISO)
microtubule  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Novel CENPJ mutation causes Seckel syndrome. Al-Dosari MS, etal., J Med Genet. 2010 Jun;47(6):411-4. doi: 10.1136/jmg.2009.076646.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. A novel deletion mutation in CENPJ gene in a Pakistani family with autosomal recessive primary microcephaly. Gul A, etal., J Hum Genet. 2006;51(9):760-4. Epub 2006 Aug 10.
5. Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome. McIntyre RE, etal., PLoS Genet. 2012;8(11):e1003022. doi: 10.1371/journal.pgen.1003022. Epub 2012 Nov 15.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11003675   PMID:11984006   PMID:12198240   PMID:15047868   PMID:15793586   PMID:17681131   PMID:20531387   PMID:21399614   PMID:22020124   PMID:23213448   PMID:24076405   PMID:24706806  
PMID:27185865  


Genomics

Comparative Map Data
Cpap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81534,742,838 - 34,806,020 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1534,742,838 - 34,802,421 (-)EnsemblGRCr8
mRatBN7.21530,627,206 - 30,690,384 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1530,627,224 - 30,686,791 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1532,618,561 - 32,678,144 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01533,769,217 - 33,828,800 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01532,027,309 - 32,086,891 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01536,745,672 - 36,809,228 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1536,746,088 - 36,798,814 (-)Ensemblrn6Rnor6.0
Rnor_5.01540,599,733 - 40,658,983 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41535,487,198 - 35,550,034 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1530,339,104 - 30,398,973 (-)NCBICelera
RGSC_v3.11535,503,314 - 35,558,495 (-)NCBI
Cytogenetic Map15p12NCBI
CPAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381324,882,279 - 24,934,000 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1324,882,276 - 24,922,889 (-)Ensemblhg38GRCh38
GRCh371325,456,417 - 25,496,999 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361324,354,412 - 24,395,085 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341324,355,171 - 24,395,018NCBI
Celera136,519,974 - 6,560,638 (-)NCBICelera
Cytogenetic Map13q12.12-q12.13NCBI
HuRef136,269,821 - 6,310,405 (-)NCBIHuRef
CHM1_11325,425,035 - 25,465,641 (-)NCBICHM1_1
T2T-CHM13v2.01324,090,519 - 24,142,252 (-)NCBIT2T-CHM13v2.0
Cpap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391456,764,218 - 56,812,950 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1456,764,218 - 56,812,882 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381456,526,761 - 56,575,489 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1456,526,761 - 56,575,425 (-)Ensemblmm10GRCm38
MGSCv371457,145,598 - 57,190,683 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361455,480,871 - 55,525,942 (-)NCBIMGSCv36mm8
Celera1454,324,537 - 54,369,663 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.28NCBI
Cpap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955497430,461 - 477,065 (-)Ensembl
ChiLan1.0NW_004955497432,595 - 497,335 (-)NCBIChiLan1.0ChiLan1.0
CPAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21424,480,417 - 24,525,024 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11315,589,327 - 15,634,675 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0136,175,936 - 6,215,565 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11324,464,045 - 24,503,432 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1324,464,045 - 24,503,432 (-)EnsemblpanPan2panpan1.1
CENPJ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12518,555,182 - 18,611,133 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2518,557,084 - 18,610,983 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2518,583,170 - 18,636,532 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02518,692,566 - 18,748,546 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2518,694,838 - 18,748,405 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12518,557,406 - 18,610,759 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02518,569,509 - 18,622,902 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02518,626,287 - 18,679,651 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cpap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945120,601,634 - 120,654,006 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367202,149,302 - 2,204,139 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367202,149,296 - 2,201,599 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPJ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl11289,653 - 355,581 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.111289,660 - 357,920 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21187,284,454 - 87,296,300 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CPAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.134,319,136 - 4,360,214 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl34,319,103 - 4,360,158 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605740,088,235 - 40,130,982 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477618,182,349 - 18,244,944 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477618,163,924 - 18,245,303 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cpap
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11268,274,336 - 68,327,597 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cpap
212 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:38
Interacting mature miRNAs:44
Transcripts:ENSRNOT00000065764
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
22 13 81 202 91 90 59 142 59 6 454 259 15 186 106 113 31 29 29

Sequence


Ensembl Acc Id: ENSRNOT00000065764   ⟹   ENSRNOP00000061061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1534,742,838 - 34,795,610 (-)Ensembl
mRatBN7.2 Ensembl1530,627,224 - 30,686,791 (-)Ensembl
Rnor_6.0 Ensembl1536,746,088 - 36,798,814 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096584   ⟹   ENSRNOP00000080142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1534,742,838 - 34,802,421 (-)Ensembl
mRatBN7.2 Ensembl1530,627,229 - 30,686,770 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000130810   ⟹   ENSRNOP00000111370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1534,745,213 - 34,802,421 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000132147   ⟹   ENSRNOP00000106573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1534,743,759 - 34,802,421 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000165696   ⟹   ENSRNOP00000110817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1534,742,838 - 34,802,421 (-)Ensembl
RefSeq Acc Id: NM_001395117   ⟹   NP_001382046
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81534,742,838 - 34,802,421 (-)NCBI
mRatBN7.21530,627,206 - 30,686,790 (-)NCBI
RefSeq Acc Id: XM_039093307   ⟹   XP_038949235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81534,742,842 - 34,801,098 (-)NCBI
mRatBN7.21530,627,206 - 30,686,771 (-)NCBI
RefSeq Acc Id: XM_039093309   ⟹   XP_038949237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81534,742,842 - 34,802,492 (-)NCBI
mRatBN7.21530,627,206 - 30,686,861 (-)NCBI
RefSeq Acc Id: XM_039093311   ⟹   XP_038949239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81534,742,842 - 34,802,475 (-)NCBI
mRatBN7.21530,627,206 - 30,686,844 (-)NCBI
RefSeq Acc Id: XM_039093312   ⟹   XP_038949240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81534,742,842 - 34,806,020 (-)NCBI
mRatBN7.21530,627,206 - 30,690,384 (-)NCBI
RefSeq Acc Id: XM_039093313   ⟹   XP_038949241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81534,742,842 - 34,801,094 (-)NCBI
mRatBN7.21530,627,206 - 30,686,771 (-)NCBI
RefSeq Acc Id: XM_039093315   ⟹   XP_038949243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81534,754,090 - 34,801,094 (-)NCBI
mRatBN7.21530,638,368 - 30,686,771 (-)NCBI
RefSeq Acc Id: XM_063274261   ⟹   XP_063130331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81534,743,194 - 34,801,094 (-)NCBI
RefSeq Acc Id: XR_010057815
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81534,747,167 - 34,801,094 (-)NCBI
Ensembl Acc Id: ENSRNOP00000061061   ⟸   ENSRNOT00000065764
RefSeq Acc Id: XP_038949240   ⟸   XM_039093312
- Peptide Label: isoform X1
- UniProtKB: A6KH99 (UniProtKB/TrEMBL),   D4A194 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949237   ⟸   XM_039093309
- Peptide Label: isoform X1
- UniProtKB: A6KH99 (UniProtKB/TrEMBL),   D4A194 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949239   ⟸   XM_039093311
- Peptide Label: isoform X1
- UniProtKB: A6KH99 (UniProtKB/TrEMBL),   D4A194 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949235   ⟸   XM_039093307
- Peptide Label: isoform X1
- UniProtKB: A6KH99 (UniProtKB/TrEMBL),   D4A194 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949241   ⟸   XM_039093313
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZNZ1 (UniProtKB/TrEMBL),   A6KH99 (UniProtKB/TrEMBL),   D4A194 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949243   ⟸   XM_039093315
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000080142   ⟸   ENSRNOT00000096584
RefSeq Acc Id: NP_001382046   ⟸   NM_001395117
- UniProtKB: A6KH99 (UniProtKB/TrEMBL),   D4A194 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130331   ⟸   XM_063274261
- Peptide Label: isoform X2
- UniProtKB: A6KH99 (UniProtKB/TrEMBL),   D4A194 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110817   ⟸   ENSRNOT00000165696
Ensembl Acc Id: ENSRNOP00000111370   ⟸   ENSRNOT00000130810
Ensembl Acc Id: ENSRNOP00000106573   ⟸   ENSRNOT00000132147
Protein Domains
Centromere protein J C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A194-F1-model_v2 AlphaFold D4A194 1-1307 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310464 AgrOrtholog
BioCyc Gene G2FUF-13631 BioCyc
Ensembl Genes ENSRNOG00000022597 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000065764.5 UniProtKB/TrEMBL
  ENSRNOT00000096584 ENTREZGENE
  ENSRNOT00000096584.2 UniProtKB/TrEMBL
  ENSRNOT00000130810.1 UniProtKB/TrEMBL
  ENSRNOT00000132147 ENTREZGENE
  ENSRNOT00000132147.1 UniProtKB/TrEMBL
  ENSRNOT00000165696 ENTREZGENE
  ENSRNOT00000165696.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.450.20 UniProtKB/TrEMBL
InterPro Tcp10/CenJ_C UniProtKB/TrEMBL
  Tcp10_C_sf UniProtKB/TrEMBL
  TCP10_fam UniProtKB/TrEMBL
NCBI Gene 305909 ENTREZGENE
PANTHER PTHR10331 UniProtKB/TrEMBL
  PTHR10331:SF23 UniProtKB/TrEMBL
Pfam Tcp10_C UniProtKB/TrEMBL
  Tubulin-bind_CPAP UniProtKB/TrEMBL
PhenoGen Cpap PhenoGen
RatGTEx ENSRNOG00000022597 RatGTEx
UniProt A0A8I5ZNZ1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LNQ8_RAT UniProtKB/TrEMBL
  A0ABK0LZN8_RAT UniProtKB/TrEMBL
  A0ABK0M6F7_RAT UniProtKB/TrEMBL
  A6KH99 ENTREZGENE, UniProtKB/TrEMBL
  D4A194 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-12-13 Cpap  centrosome assembly and centriole elongation protein  Cenpj  centromere protein J  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Cenpj  centromere protein J   Cenpj_predicted  centromere protein J (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cenpj_predicted  centromere protein J (predicted)      Symbol and Name status set to approved 70820 APPROVED