Dtl (denticleless E3 ubiquitin protein ligase adapter) - Rat Genome Database

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Gene: Dtl (denticleless E3 ubiquitin protein ligase adapter) Rattus norvegicus
Analyze
Symbol: Dtl
Name: denticleless E3 ubiquitin protein ligase adapter (Ensembl:denticleless E3 ubiquitin protein ligase homolog)
RGD ID: 1310439
Description: Predicted to enable protein-macromolecule adaptor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including protein ubiquitination; regulation of G2/M transition of mitotic cell cycle; and translesion synthesis. Predicted to be located in centrosome. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and Cul4B-RING E3 ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human DTL (denticleless E3 ubiquitin protein ligase homolog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: denticleless E3 ubiquitin protein ligase homolog; denticleless E3 ubiquitin protein ligase homolog (Drosophila); denticleless homolog; denticleless homolog (Drosophila); denticleless protein homolog; LOC100909566; LOC305073; RGD1310439; similar to retinoic acid-regulated nuclear matrix-associated protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813105,646,908 - 105,685,921 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13105,646,908 - 105,686,174 (-)EnsemblGRCr8
mRatBN7.213103,115,810 - 103,155,029 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,117,186 - 103,154,890 (-)EnsemblmRatBN7.2
Rnor_6.013110,219,276 - 110,257,345 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,220,283 - 110,257,367 (-)Ensemblrn6Rnor6.0
Rnor_5.013114,783,177 - 114,821,239 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413107,603,353 - 107,640,812 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera13102,555,070 - 102,594,148 (-)NCBICelera
RGSC_v3.113107,792,703 - 107,830,078 (-)NCBI
Cytogenetic Map13q27NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-hexachlorocyclohexane  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
DDT  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
epoxiconazole  (ISO)
erastin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
genistein  (ISO)
GSK-J4  (ISO)
GW 7647  (ISO)
hexadecanoic acid  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
lucanthone  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
pravastatin  (EXP,ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
senecionine  (EXP)
Senkirkine  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16949367   PMID:17085480   PMID:17106265   PMID:18794347   PMID:20129063   PMID:21628527   PMID:26431207  


Genomics

Comparative Map Data
Dtl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813105,646,908 - 105,685,921 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13105,646,908 - 105,686,174 (-)EnsemblGRCr8
mRatBN7.213103,115,810 - 103,155,029 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,117,186 - 103,154,890 (-)EnsemblmRatBN7.2
Rnor_6.013110,219,276 - 110,257,345 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,220,283 - 110,257,367 (-)Ensemblrn6Rnor6.0
Rnor_5.013114,783,177 - 114,821,239 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413107,603,353 - 107,640,812 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera13102,555,070 - 102,594,148 (-)NCBICelera
RGSC_v3.113107,792,703 - 107,830,078 (-)NCBI
Cytogenetic Map13q27NCBI
DTL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381212,035,748 - 212,105,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1212,035,553 - 212,107,400 (+)Ensemblhg38GRCh38
GRCh371212,209,090 - 212,278,355 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,275,754 - 210,344,809 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1185,435,998 - 185,505,287 (+)NCBICelera
Cytogenetic Map1q32.3NCBI
HuRef1182,885,955 - 182,955,234 (+)NCBIHuRef
CHM1_11213,481,305 - 213,550,518 (+)NCBICHM1_1
T2T-CHM13v2.01211,281,835 - 211,351,118 (+)NCBIT2T-CHM13v2.0
Dtl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,269,468 - 191,307,656 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1191,269,468 - 191,307,656 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381191,537,356 - 191,575,544 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,537,356 - 191,575,544 (-)Ensemblmm10GRCm38
MGSCv371193,361,244 - 193,399,413 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361193,237,980 - 193,276,149 (-)NCBIMGSCv36mm8
Celera1198,486,790 - 198,526,178 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map196.44NCBI
Dtl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554065,254,558 - 5,299,573 (-)Ensembl
ChiLan1.0NW_0049554065,256,057 - 5,299,573 (-)NCBIChiLan1.0ChiLan1.0
DTL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2137,300,460 - 37,367,503 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1137,264,941 - 37,331,990 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01187,603,600 - 187,672,006 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11192,466,408 - 192,535,071 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1192,466,408 - 192,535,071 (+)EnsemblpanPan2panpan1.1
DTL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1710,323,842 - 10,368,529 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl710,323,559 - 10,369,560 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha79,901,494 - 9,944,363 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0710,030,330 - 10,073,724 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl710,030,370 - 10,073,719 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.179,952,445 - 9,997,665 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0710,055,386 - 10,098,331 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0710,179,868 - 10,228,472 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dtl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934464,087,630 - 64,149,419 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365571,347,991 - 1,389,836 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365571,347,991 - 1,389,836 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DTL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9131,227,705 - 131,275,451 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19131,225,840 - 131,275,426 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29144,272,743 - 144,325,340 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DTL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12517,418,078 - 17,485,320 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2517,418,090 - 17,485,164 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605517,940,853 - 18,008,338 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dtl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477117,612,284 - 17,662,405 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477117,612,264 - 17,660,772 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dtl
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11069,627,901 - 69,665,385 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dtl
92 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:179
Count of miRNA genes:132
Interacting mature miRNAs:138
Transcripts:ENSRNOT00000005576, ENSRNOT00000005628
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 90 89 58 87 58 6 347 187 11 141 78 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000005576   ⟹   ENSRNOP00000005576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13105,646,908 - 105,686,174 (-)Ensembl
mRatBN7.2 Ensembl13103,117,186 - 103,154,890 (-)Ensembl
Rnor_6.0 Ensembl13110,220,283 - 110,257,367 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095446   ⟹   ENSRNOP00000083831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13105,646,908 - 105,685,418 (-)Ensembl
mRatBN7.2 Ensembl13103,117,186 - 103,154,890 (-)Ensembl
RefSeq Acc Id: NM_001427431   ⟹   NP_001414360
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,921 (-)NCBI
RefSeq Acc Id: XM_017599014   ⟹   XP_017454503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,679,386 (-)NCBI
mRatBN7.213103,115,810 - 103,148,301 (-)NCBI
Rnor_6.013110,219,276 - 110,250,749 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091504   ⟹   XP_038947432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,873 (-)NCBI
mRatBN7.213103,115,810 - 103,154,811 (-)NCBI
RefSeq Acc Id: XM_039091506   ⟹   XP_038947434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,902 (-)NCBI
mRatBN7.213103,115,810 - 103,154,843 (-)NCBI
RefSeq Acc Id: XM_063272398   ⟹   XP_063128468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,198 (-)NCBI
RefSeq Acc Id: XM_063272399   ⟹   XP_063128469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,466 (-)NCBI
RefSeq Acc Id: XM_063272400   ⟹   XP_063128470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,739 (-)NCBI
RefSeq Acc Id: XP_017454503   ⟸   XM_017599014
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000005576   ⟸   ENSRNOT00000005576
RefSeq Acc Id: XP_038947434   ⟸   XM_039091506
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947432   ⟸   XM_039091504
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083831   ⟸   ENSRNOT00000095446
RefSeq Acc Id: NP_001414360   ⟸   NM_001427431
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128470   ⟸   XM_063272400
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128469   ⟸   XM_063272399
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128468   ⟸   XM_063272398
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZER4-F1-model_v2 AlphaFold D3ZER4 1-783 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699133
Promoter ID:EPDNEW_R9642
Type:initiation region
Name:Dtl_1
Description:denticleless E3 ubiquitin protein ligase homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013110,257,288 - 110,257,348EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310439 AgrOrtholog
BioCyc Gene G2FUF-16841 BioCyc
Ensembl Genes ENSRNOG00000004195 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005576 ENTREZGENE
  ENSRNOT00000005576.9 UniProtKB/TrEMBL
  ENSRNOT00000095446 ENTREZGENE
  ENSRNOT00000095446.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro WD-repeat_CDT2_adapter UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene 305073 ENTREZGENE
PANTHER DENTICLELESS PROTEIN HOMOLOG UniProtKB/TrEMBL
  LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PhenoGen Dtl PhenoGen
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004195 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A8I5ZW16_RAT UniProtKB/TrEMBL
  A6JGZ8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZER4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Dtl  denticleless E3 ubiquitin protein ligase adapter  Dtl  denticleless E3 ubiquitin protein ligase homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-03-09 Dtl  denticleless E3 ubiquitin protein ligase homolog  LOC100909566  denticleless protein homolog  Data merged from RGD:6503029 737654 PROVISIONAL
2016-01-27 Dtl  denticleless E3 ubiquitin protein ligase homolog  Dtl  denticleless E3 ubiquitin protein ligase homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-16 Dtl  denticleless E3 ubiquitin protein ligase homolog (Drosophila)  Dtl  denticleless homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100909566  denticleless protein homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-27 Dtl  denticleless homolog (Drosophila)  RGD1310439_predicted  similar to retinoic acid-regulated nuclear matrix-associated protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1310439_predicted  similar to retinoic acid-regulated nuclear matrix-associated protein (predicted)  LOC305073_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC305073_predicted  similar to retinoic acid-regulated nuclear matrix-associated protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL