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Gene: Prr27 (proline rich 27) Rattus norvegicus

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Symbol:

Prr27

Name:

proline rich 27

RGD ID:

1310384

Description:

Orthologous to human PRR27 (proline rich 27); INTERACTS WITH bisphenol A; fenvalerate; (+)-catechin (ortholog).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical LOC289530; LOC289530; proline-rich protein 27; RGD1310384

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PRR27 (proline rich 27)	HGNC	EggNOG, Ensembl, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Prr27 (proline rich 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PRR27 (proline rich 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PRR27 (proline rich 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Prr27 (proline rich 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PRR27 (proline rich 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PRR27 (proline rich 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Prr27 (proline rich 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Prr27 (proline rich 27)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PRR27 (proline rich 27)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PRR27 (proline rich 27)	Alliance	DIOPT (HGNC\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	20,511,998 - 20,527,861 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	20,512,058 - 20,527,838 (-)	Ensembl				GRCr8
mRatBN7.2	14	20,232,757 - 20,248,617 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	20,232,758 - 20,248,595 (-)	Ensembl				mRatBN7.2
Rnor_6.0	14	21,882,454 - 21,898,651 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	21,882,456 - 21,898,284 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	21,797,530 - 21,813,398 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	21,755,854 - 21,764,725 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	19,635,518 - 19,651,726 (-)	NCBI		Celera
RGSC_v3.1	14	21,755,853 - 21,771,524 (-)	NCBI
Cytogenetic Map	14	p21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

17beta-estradiol (ISO)

bisphenol A (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

fenvalerate (EXP)

permethrin (ISO)

valproic acid (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19199708

Genomics

Comparative Map Data

Prr27
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	20,511,998 - 20,527,861 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	20,512,058 - 20,527,838 (-)	Ensembl				GRCr8
mRatBN7.2	14	20,232,757 - 20,248,617 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	20,232,758 - 20,248,595 (-)	Ensembl				mRatBN7.2
Rnor_6.0	14	21,882,454 - 21,898,651 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	21,882,456 - 21,898,284 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	21,797,530 - 21,813,398 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	21,755,854 - 21,764,725 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	19,635,518 - 19,651,726 (-)	NCBI		Celera
RGSC_v3.1	14	21,755,853 - 21,771,524 (-)	NCBI
Cytogenetic Map	14	p21	NCBI

PRR27
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	70,154,237 - 70,166,609 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	70,133,616 - 70,176,799 (+)	Ensembl			hg38	GRCh38
GRCh37	4	71,019,954 - 71,032,326 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	71,054,493 - 71,066,915 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	4	68,377,867 - 68,390,293 (+)	NCBI		Celera
Cytogenetic Map	4	q13.3	NCBI
HuRef	4	66,822,148 - 66,834,583 (+)	NCBI		HuRef
CHM1_1	4	71,056,306 - 71,068,725 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	73,493,513 - 73,505,908 (+)	NCBI		T2T-CHM13v2.0

Prr27
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	87,973,556 - 87,994,245 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	87,973,545 - 87,994,246 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	87,825,697 - 87,846,386 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	87,825,686 - 87,846,387 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	88,254,722 - 88,275,411 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	88,900,258 - 88,920,947 (+)	NCBI		MGSCv36	mm8
MGSCv36	5	87,430,096 - 87,450,785 (+)	NCBI		MGSCv36	mm8
Cytogenetic Map	5	E1	NCBI
cM Map	5	43.56	NCBI

PRR27
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	59,915,874 - 59,928,207 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	60,112,418 - 60,124,770 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	54,056,783 - 54,071,269 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	60,403,145 - 60,412,691 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	60,405,302 - 60,412,502 (-)	Ensembl			panPan2	panpan1.1

PRR27
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	59,540,017 - 59,555,218 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	59,540,011 - 59,555,213 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	59,266,846 - 59,282,040 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	60,334,402 - 60,349,574 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	60,334,403 - 60,345,936 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	59,948,594 - 59,963,780 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	59,453,105 - 59,468,352 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	60,600,002 - 60,615,185 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Prr27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	16,023,875 - 16,028,880 (-)	NCBI		HiC_Itri_2

PRR27
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	8	67,023,892 - 67,028,934 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	148,327,808 - 148,347,301 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRR27
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	18,617,731 - 18,640,986 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	18,631,892 - 18,636,387 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666084	4,293,186 - 4,299,565 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prr27
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	1,114,140 - 1,126,852 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Prr27
117 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	218
Count of miRNA genes:	140
Interacting mature miRNAs:	144
Transcripts:	ENSRNOT00000036314, ENSRNOT00000048341, ENSRNOT00000068032
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300114	Srn2	Serum renin concentration QTL 2	3.27		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	3957878	21572472	Rat
631528	Scl11	Serum cholesterol level QTL 11	4.9		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	14	17875645	36079022	Rat
7411573	Bw139	Body weight QTL 139	4.7	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	14	1	40068101	Rat
9589814	Gluco67	Glucose level QTL 67	4.54	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	40068101	Rat
731183	Pia20	Pristane induced arthritis QTL 20	3.55		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	9393298	39411170	Rat
631212	Bw5	Body weight QTL5	5.43		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	14	11334906	30674469	Rat
2302277	Gluco38	Glucose level QTL 38	5.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	28389666	Rat
1331740	Bw26	Body weight QTL 26	3.028		body mass (VT:0001259)	body weight (CMO:0000012)	14	3957878	31121464	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8621398	53621398	Rat
61420	Pia6	Pristane induced arthritis QTL 6	4.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	14	18915454	42433608	Rat
70195	Mcs8	Mammary carcinoma susceptibility QTL 8	4.28		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	14	3957878	24886169	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	100078267	Rat
2313397	Coatc1	Coat color QTL1			coat/hair pigmentation trait (VT:0010463)	coat/hair color measurement (CMO:0001808)	14	18895192	63895192	Rat
631262	Tcas4	Tongue tumor susceptibility QTL 4	7.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	14	17906726	54251504	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41415516	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1	31893212	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8621398	53621398	Rat
1300140	Srn3	Serum renin concentration QTL 3	3.19		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	15137594	31238250	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

appendage	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
3	11	7	7	5	2	5	6	13	4	4	2	28	2

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001432712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006221702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006221703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006221704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273817	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC097835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000036314 ⟹ ENSRNOP00000034677

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	20,512,058 - 20,527,838 (-)	Ensembl
mRatBN7.2 Ensembl	14	20,232,758 - 20,248,595 (-)	Ensembl
Rnor_6.0 Ensembl	14	21,882,456 - 21,898,284 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096416 ⟹ ENSRNOP00000080840

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	20,512,058 - 20,520,870 (-)	Ensembl
mRatBN7.2 Ensembl	14	20,232,758 - 20,248,595 (-)	Ensembl

RefSeq Acc Id:

XM_006250795 ⟹ XP_006250857

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	20,511,998 - 20,527,857 (-)	NCBI
mRatBN7.2	14	20,232,757 - 20,248,615 (-)	NCBI
Rnor_6.0	14	21,882,454 - 21,898,648 (-)	NCBI
Rnor_5.0	14	21,797,530 - 21,813,398 (-)	NCBI

Sequence:

show sequence

GGCAGTGCTTATTCCGTTTAGAAAGCTGTTTTACATATTTAGTTATAGGGGAGCCGTCAGATGG
GTTCATAGGTAACACTGAGGGATGTTTTTGTTACAAAGGCGAGGAGTGAAGTGTGAATCGACGG
CACCATAAACGATCCCTGTCCTTACTCCTCCTAGCATAGCTCAGTCTATCAAGTTCCCCTTATC
CCAAGCTCTTTCCTGTGCAGTACAAAGACTCAGCAGATTTTCCGGAAAAGGAGGCCCTGAAGCG
TCTTTTGAAAAGGCAGAGCAGTAATAAGCTCCGAGAACTCTTATTTGTCATTCTTAGAACCCTC
CATTCCTTAGCAATCTGCTGATGCTGCATTCTGTCTCTTACATTCTCCGGTGGCCTCACTTCTC
GCAGACTTTATCCTTCGAAATTTAAAATATTATCCGCATACTTAATACAATTCTTCTGCCTTTC
TGCACTGAAGCAACTCTCCCTGGACAATATCTGGCCACTTAAGACTCTGAGATGAATGTTGACT
TCTGTCCCCTCTAAGCATCTGAGTCTCAAAGCTCCATCAAGATGAAGTTACTTCTTTGGGCCTG
CATCATGTGTGTCGCTTTTGCAAAGAGGAGACGTTATCCCTTCATTCACAAGAAATCGCCCTCA
TCCACTGAAGAGGATTACTTTGGAAATCGCTACCCACTTAAACCATCTCTGAATATCCCCTATG
GCCTATGGAATGATAATTTGCCACCTTTTGTTTTGCCTCCTCTTAACACTCAACAAGGAAACGC
CATCACCAAATTCTCCGGAAATTCTGAGCTTGAAAGAGGGCTATCTCTATATCCTTGGATTCCC
ACTTCTCCCAAATTTCGCTATATATACCAAAACTATAACTACCCCGCAGATGCGCCACTGAATG
GTCCTGCAATTGTTCCTCTTCCTCCTCCCCGACCCTTTCCTCCCAGGCCATATCCCTTTGTCAT
CCCTCCAAAGATTTCTGTCATCTCACCCATTGGACATGAGCCTGTAGCAGCTTCTGCTGTGCCT
GCTGAAGGCGAGGCTTTGGTACCTGAGATCCCTGTAGATAAACATATTGCGGGTCTGCCTCCGG
TGATCAAACTTGCAACACCCATGCCACCCTCTGAACCCAAATCTCTTGCACCTGAACCTGCTCC
AGCCCACTTTGCTGCACCCGAGCCTGTCCCAGTCCATTTTCTTGCACCGGAACCTGCTCATCCC
CAGCCAGAGATGGCTGTGCCTGCCGCACCCCACCCCATGGCACCTGAACCCGCTGTAGCCCTAT
CTGTGGGAGCACAGCCTCTAGAAGCTGAAACCCCTGCAGGCCAGTCTCCTGAGAACAAACCTAC
TTCAGGTGAGCTTGCTGTAGCACAGTCTCTGCCGACCTTGCCTGCTGCAGGCCAACCTCCTCCG
GATGAACTCATGGCAAGCCAGTCTCTTGTGGGAAAACTTATTACAGCTGAGCCTACTGAAGCAA
AACAGGAGGGACCTGAACCTTTTGAGGCCAAATCTGCTAGCCACGAACCACAGCCGTTTTCTAC
CAGATGCTGATGAACCAATCAAAGAAACCTAAACATTCTTTCTTTTCCCAACAAATATTCCCTG
TTTTATTAAAGCTATCAGTCTCTCCACA

hide sequence

RefSeq Acc Id:

XM_006250796 ⟹ XP_006250858

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	20,511,998 - 20,527,857 (-)	NCBI
mRatBN7.2	14	20,232,757 - 20,248,615 (-)	NCBI
Rnor_6.0	14	21,882,456 - 21,898,648 (-)	NCBI
Rnor_5.0	14	21,797,530 - 21,813,398 (-)	NCBI

Sequence:

show sequence

GGCAGTGCTTATTCCGTTTAGAAAGCTGTTTTACATATTTAGTTATAGGGGAGCCGTCAGATGG
GTTCATAGGTAACACTGAGGGATGTTTTTGTTACAAAGGCGAGGAGTGAAGTGTGAATCGACGG
CACCATAAACGATCCCTGTCCTTACTCCTCCTAGCATAGCTCAGTCTATCAAGTTCCCCTTATC
CCAAGCTCTTTCCTGTGCAGTACAAAGACTCAGCAGATTTTCCGGAAAAGGAGGCCCTGAAGCG
TCTTTTGAAAAGGCAGAGCAGTAATAAGCTCCGAGAACTCTTATTTGTCATTCTTAGAACCCTC
CATTCCTTAGCAATCTGCTGATGCTGCATTCTGTCTCTTACATTCTCCGGTGGCCTCACTTCTC
GCAGACTTTATCCTTCGAAATTTAAAATATTATCCGCATACTTAATACAATTCTTCTGCCTTTC
TGCACTGAAGCAACTCTCCCTGGACAATATCTGGCCACTTAAGACTCTGAGATGAATGTTGACT
TCTGTCCCCTCTAAGCATCTGAGTCTCAAAGCTCCATCAAGATGAAGTTACTTCTTTGGGCCTG
CATCATGTGTGTCGCTTTTGCAAAGAGGAGACGTTATCCCTTCATTCACAAGAAATCGCCCTCA
TCCACTGAAGAGGATTACTTTGGAAATCGCTACCCACTTAAACCATCTCTGAATATCCCCTATG
GCCTATGGAATGATAATTTGCCACCTTTTGTTTTGCCTCCTCTTAACACTCAACAAGGAAACGC
CATCACCAAATTCTCCGGAAATTCTGAGCTTGAAAGAGGGCTATCTCTATATCCTTGGATTCCC
ACTTCTCCCAAATTTCGCTATATATACCAAAACTATAACTACCCCGCAGATGCGCCACTGAATG
GTCCTGCAATTGTTCCTCTTCCTCCTCCCCGACCCTTTCCTCCCAGGCCATATCCCTTTGTCAT
CCCTCCAAAGATTTCTGTCATCTCACCCATTGGACATGAGCCTGTAGCAGCTTCTGCTGTGCCT
GCTGAAGGCGAGGCTTTGGTACCTGAGATCCCTGTAGATAAACATATTGCGGGTCTGCCTCCGG
TGATCAAACTTGCAACACCCATGCCACCCTCTGAACCCAAATCTCTTGCACCTGAACCTGCTCC
AGCCCACTTTGCTGCACCCGAGCCTGTCCCAGTCCATTTTCTTGCACCGGAACCTGCTCATCCC
CAGCCAGAGATGGCTGTGCCTGCCGCACCCCACCCCATGGCACCTGAACCCGCTGTAGCCCTAT
CTGTGGGAGCACAGCCTCTAGAAGCTGAAACCCCTGCAGGCCAGTCTCCTGAGAACAAACCTAC
TTCAGGTGAGCTTGCTGTAGCACAGTCTCTGCCGACCTTGCCTGCTGCAGGCCAACCTCCTCCG
GATGAACTCATGGCAAGCCAGTCTCTTGTGGGAAAACTTATTACAGCTGAGCCTACTGAAGCAA
AACAGGAGGGACCTGAACCTTTTGAGGCCAAATCTGCTAGCCACGAACCACAGCCGTTTTCTAC
CAGGTAGAGAAGTGAGATTTTTCTGGAGAAGAGAGTGATATTCATTTGTTTCTATGCTGATGAA
CCAATCAAAGAAACCTAAACATTCTTTCTTTTCCCAACAAATATTCCCTGTTTTATTAAAGCTA
TCAGTCTCTCCA

hide sequence

RefSeq Acc Id:

XM_006250797 ⟹ XP_006250859

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	20,511,998 - 20,527,859 (-)	NCBI
mRatBN7.2	14	20,232,757 - 20,248,617 (-)	NCBI
Rnor_6.0	14	21,882,454 - 21,898,651 (-)	NCBI
Rnor_5.0	14	21,797,530 - 21,813,398 (-)	NCBI

Sequence:

show sequence

AAGGGCAGTGCTTATTCCGTTTAGAAAGCTGTTTTACATATTTAGTTATAGGGGAGCCGTCAGA
TGGGTTCATAGGTAACACTGAGGGATGTTTTTGTTACAAAGGCGAGGAGTGAAGTGTGAATCGA
CGGCACCATAAACGATCCCTGTCCTTACTCCTCCTAGCATAGCTCAGTCTATCAAGTTCCCCTT
ATCCCAAGCTCTTTCCTGTGCAGTACAAAGACTCAGCAGATTTTCCGGAAAAGGAGGCCCTGAA
GCGTCTTTTGAAAAGGCAGAGCAGTAATAAGCTCCGAGAACTCTTATTTGTCATTCTTAGAACC
CTCCATTCCTTAGCAATCTGCTGATGCTGCATTCTGTCTCTTACATTCTCCGGTGGCCTCACTT
CTCGCAGACTTTATCCTTCGAAATTTAAAATATTATCCGCATACTTAATACAATTCTTCTGCCT
TTCTGCACTGAAGCAACTCTCCCTGGACAATATCTGGCCACTTAAGACTCTGAGATGAATGTTG
ACTTCTGTCCCCTCTAAGCATCTGAGTCTCAAAGCTCCATCAAGATGAAGTTACTTCTTTGGGC
CTGCATCATGTGTGTCGCTTTTGCAAAGAGGAGACGTTATCCCTTCATTCACAAGGATTACTTT
GGAAATCGCTACCCACTTAAACCATCTCTGAATATCCCCTATGGCCTATGGAATGATAATTTGC
CACCTTTTGTTTTGCCTCCTCTTAACACTCAACAAGGAAACGCCATCACCAAATTCTCCGGAAA
TTCTGAGCTTGAAAGAGGGCTATCTCTATATCCTTGGATTCCCACTTCTCCCAAATTTCGCTAT
ATATACCAAAACTATAACTACCCCGCAGATGCGCCACTGAATGGTCCTGCAATTGTTCCTCTTC
CTCCTCCCCGACCCTTTCCTCCCAGGCCATATCCCTTTGTCATCCCTCCAAAGATTTCTGTCAT
CTCACCCATTGGACATGAGCCTGTAGCAGCTTCTGCTGTGCCTGCTGAAGGCGAGGCTTTGGTA
CCTGAGATCCCTGTAGATAAACATATTGCGGGTCTGCCTCCGGTGATCAAACTTGCAACACCCA
TGCCACCCTCTGAACCCAAATCTCTTGCACCTGAACCTGCTCCAGCCCACTTTGCTGCACCCGA
GCCTGTCCCAGTCCATTTTCTTGCACCGGAACCTGCTCATCCCCAGCCAGAGATGGCTGTGCCT
GCCGCACCCCACCCCATGGCACCTGAACCCGCTGTAGCCCTATCTGTGGGAGCACAGCCTCTAG
AAGCTGAAACCCCTGCAGGCCAGTCTCCTGAGAACAAACCTACTTCAGGTGAGCTTGCTGTAGC
ACAGTCTCTGCCGACCTTGCCTGCTGCAGGCCAACCTCCTCCGGATGAACTCATGGCAAGCCAG
TCTCTTGTGGGAAAACTTATTACAGCTGAGCCTACTGAAGCAAAACAGGAGGGACCTGAACCTT
TTGAGGCCAAATCTGCTAGCCACGAACCACAGCCGTTTTCTACCAGATGCTGATGAACCAATCA
AAGAAACCTAAACATTCTTTCTTTTCCCAACAAATATTCCCTGTTTTATTAAAGCTATCAGTCT
CTCCACA

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RefSeq Acc Id:

XM_039092685 ⟹ XP_038948613

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	20,511,998 - 20,527,858 (-)	NCBI
mRatBN7.2	14	20,232,757 - 20,248,616 (-)	NCBI

RefSeq Acc Id:

XM_063273817 ⟹ XP_063129887

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	20,511,998 - 20,527,861 (-)	NCBI

RefSeq Acc Id:

XM_063273818 ⟹ XP_063129888

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	20,511,998 - 20,527,860 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001419641	(Get FASTA)	NCBI Sequence Viewer
	NP_001419643	(Get FASTA)	NCBI Sequence Viewer
	NP_001419646	(Get FASTA)	NCBI Sequence Viewer
	NP_001419667	(Get FASTA)	NCBI Sequence Viewer
	XP_006250857	(Get FASTA)	NCBI Sequence Viewer
	XP_006250858	(Get FASTA)	NCBI Sequence Viewer
	XP_006250859	(Get FASTA)	NCBI Sequence Viewer
	XP_038948613	(Get FASTA)	NCBI Sequence Viewer
	XP_063129887	(Get FASTA)	NCBI Sequence Viewer
	XP_063129888	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034677
	ENSRNOP00000034677.7
	ENSRNOP00000080840.2

RefSeq Acc Id:

XP_006250859 ⟸ XM_006250797

- Peptide Label:

isoform X3

- Sequence:

show sequence

MKLLLWACIMCVAFAKRRRYPFIHKDYFGNRYPLKPSLNIPYGLWNDNLPPFVLPPLNTQQGNA
ITKFSGNSELERGLSLYPWIPTSPKFRYIYQNYNYPADAPLNGPAIVPLPPPRPFPPRPYPFVI
PPKISVISPIGHEPVAASAVPAEGEALVPEIPVDKHIAGLPPVIKLATPMPPSEPKSLAPEPAP
AHFAAPEPVPVHFLAPEPAHPQPEMAVPAAPHPMAPEPAVALSVGAQPLEAETPAGQSPENKPT
SGELAVAQSLPTLPAAGQPPPDELMASQSLVGKLITAEPTEAKQEGPEPFEAKSASHEPQPFST
RC

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RefSeq Acc Id:

XP_006250857 ⟸ XM_006250795

- Peptide Label:

isoform X1

- Sequence:

show sequence

MKLLLWACIMCVAFAKRRRYPFIHKKSPSSTEEDYFGNRYPLKPSLNIPYGLWNDNLPPFVLPP
LNTQQGNAITKFSGNSELERGLSLYPWIPTSPKFRYIYQNYNYPADAPLNGPAIVPLPPPRPFP
PRPYPFVIPPKISVISPIGHEPVAASAVPAEGEALVPEIPVDKHIAGLPPVIKLATPMPPSEPK
SLAPEPAPAHFAAPEPVPVHFLAPEPAHPQPEMAVPAAPHPMAPEPAVALSVGAQPLEAETPAG
QSPENKPTSGELAVAQSLPTLPAAGQPPPDELMASQSLVGKLITAEPTEAKQEGPEPFEAKSAS
HEPQPFSTRC

hide sequence

RefSeq Acc Id:

XP_006250858 ⟸ XM_006250796

- Peptide Label:

isoform X2

- Sequence:

show sequence

MKLLLWACIMCVAFAKRRRYPFIHKKSPSSTEEDYFGNRYPLKPSLNIPYGLWNDNLPPFVLPP
LNTQQGNAITKFSGNSELERGLSLYPWIPTSPKFRYIYQNYNYPADAPLNGPAIVPLPPPRPFP
PRPYPFVIPPKISVISPIGHEPVAASAVPAEGEALVPEIPVDKHIAGLPPVIKLATPMPPSEPK
SLAPEPAPAHFAAPEPVPVHFLAPEPAHPQPEMAVPAAPHPMAPEPAVALSVGAQPLEAETPAG
QSPENKPTSGELAVAQSLPTLPAAGQPPPDELMASQSLVGKLITAEPTEAKQEGPEPFEAKSAS
HEPQPFSTR

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Ensembl Acc Id:

ENSRNOP00000034677 ⟸ ENSRNOT00000036314

RefSeq Acc Id:	XP_038948613 ⟸ XM_039092685
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000080840 ⟸ ENSRNOT00000096416

RefSeq Acc Id:	XP_063129887 ⟸ XM_063273817
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063129888 ⟸ XM_063273818
- Peptide Label:	isoform X4

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZPI2-F1-model_v2	AlphaFold	D3ZPI2	1-330	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699253

Promoter ID:

EPDNEW_R9771

Type:

initiation region

Name:

Prr27_1

Description:

proline rich 27

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	21,898,301 - 21,898,361	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310384	AgrOrtholog
BioCyc Gene	G2FUF-16133	BioCyc
Ensembl Genes	ENSRNOG00000023342	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000036314	ENTREZGENE
	ENSRNOT00000036314.9	UniProtKB/TrEMBL
	ENSRNOT00000096416.2	UniProtKB/TrEMBL
InterPro	PRR27	UniProtKB/TrEMBL
KEGG Report	rno:289530	UniProtKB/TrEMBL
NCBI Gene	289530	ENTREZGENE
PANTHER	PROLINE-RICH PROTEIN 27	UniProtKB/TrEMBL
	PTHR39415	UniProtKB/TrEMBL
PhenoGen	Prr27	PhenoGen
RatGTEx	ENSRNOG00000023342	RatGTEx
UniProt	A0A8I5ZR72	ENTREZGENE, UniProtKB/TrEMBL
	D3ZPI2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-03-13	Prr27	proline rich 27	RGD1310384	hypothetical LOC289530	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1310384	hypothetical LOC289530	RGD1310384_predicted	hypothetical LOC289530 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1310384_predicted	hypothetical LOC289530 (predicted)	LOC289530_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC289530_predicted	hypothetical LOC289530 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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