Phyhd1 (phytanoyl-CoA dioxygenase domain containing 1) - Rat Genome Database

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Pathways
Gene: Phyhd1 (phytanoyl-CoA dioxygenase domain containing 1) Rattus norvegicus
Analyze
Symbol: Phyhd1
Name: phytanoyl-CoA dioxygenase domain containing 1
RGD ID: 1310377
Description: Predicted to enable 2-oxoglutarate-dependent dioxygenase activity. Orthologous to human PHYHD1 (phytanoyl-CoA dioxygenase domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC296621; MGC109475; phytanoyl-CoA dioxygenase domain-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8333,933,487 - 33,951,614 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl333,937,898 - 33,951,614 (+)EnsemblGRCr8
mRatBN7.2313,535,670 - 13,553,797 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,540,056 - 13,553,797 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx316,611,935 - 16,625,306 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,196,900 - 25,210,269 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,442,725 - 23,456,144 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,828,052 - 8,846,126 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,832,740 - 8,846,125 (+)Ensemblrn6Rnor6.0
Rnor_5.0314,182,617 - 14,199,076 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.439,310,513 - 9,325,611 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera38,306,974 - 8,320,347 (+)NCBICelera
RGSC_v3.139,310,812 - 9,325,909 (+)NCBI
Cytogenetic Map3p12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data
Phyhd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8333,933,487 - 33,951,614 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl333,937,898 - 33,951,614 (+)EnsemblGRCr8
mRatBN7.2313,535,670 - 13,553,797 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,540,056 - 13,553,797 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx316,611,935 - 16,625,306 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,196,900 - 25,210,269 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,442,725 - 23,456,144 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,828,052 - 8,846,126 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,832,740 - 8,846,125 (+)Ensemblrn6Rnor6.0
Rnor_5.0314,182,617 - 14,199,076 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.439,310,513 - 9,325,611 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera38,306,974 - 8,320,347 (+)NCBICelera
RGSC_v3.139,310,812 - 9,325,909 (+)NCBI
Cytogenetic Map3p12NCBI
PHYHD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,920,982 - 128,942,041 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,920,966 - 128,942,042 (+)Ensemblhg38GRCh38
GRCh379131,683,261 - 131,704,320 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,722,995 - 130,744,141 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349128,763,240 - 128,783,870NCBI
Celera9102,335,033 - 102,356,179 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,290,885 - 101,312,039 (+)NCBIHuRef
CHM1_19131,834,184 - 131,855,369 (+)NCBICHM1_1
T2T-CHM13v2.09141,125,761 - 141,145,449 (+)NCBIT2T-CHM13v2.0
Phyhd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39230,156,215 - 30,172,161 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl230,156,215 - 30,172,161 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38230,266,203 - 30,282,149 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,266,203 - 30,282,149 (+)Ensemblmm10GRCm38
MGSCv37230,122,069 - 30,137,668 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36230,088,558 - 30,104,157 (+)NCBIMGSCv36mm8
Celera229,970,940 - 29,986,905 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.46NCBI
Phyhd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,298,069 - 1,307,940 (+)Ensembl
ChiLan1.0NW_0049555701,298,243 - 1,308,230 (+)NCBIChiLan1.0ChiLan1.0
PHYHD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,410,420 - 10,432,470 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,412,765 - 10,434,859 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09100,042,756 - 100,063,998 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,708,254 - 128,728,092 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,708,254 - 128,728,092 (+)EnsemblpanPan2panpan1.1
PHYHD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,717,430 - 54,730,383 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,717,434 - 54,729,533 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha953,912,984 - 53,925,645 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0955,638,499 - 55,651,160 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,638,507 - 55,650,586 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,399,634 - 54,412,300 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,712,000 - 54,724,658 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,805,554 - 54,818,220 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Phyhd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,621,127 - 196,633,365 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,390,820 - 16,401,901 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,391,055 - 16,401,892 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHYHD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1269,242,734 - 269,254,670 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11269,241,955 - 269,254,708 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PHYHD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,219,448 - 9,240,209 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,219,438 - 9,234,674 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666096247,581 - 336,806 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phyhd1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v155,350,230 - 5,368,474 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Phyhd1
74 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:52
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000022552
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)33083238444921701Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000022552   ⟹   ENSRNOP00000022552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl333,937,898 - 33,951,606 (+)Ensembl
mRatBN7.2 Ensembl313,540,090 - 13,553,786 (+)Ensembl
Rnor_6.0 Ensembl38,832,740 - 8,846,125 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095142   ⟹   ENSRNOP00000093539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl333,940,533 - 33,951,614 (+)Ensembl
mRatBN7.2 Ensembl313,542,716 - 13,553,797 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112840   ⟹   ENSRNOP00000090750
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl333,938,221 - 33,951,606 (+)Ensembl
mRatBN7.2 Ensembl313,540,056 - 13,553,787 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000139700   ⟹   ENSRNOP00000110843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl333,940,829 - 33,951,614 (+)Ensembl
RefSeq Acc Id: NM_001013081   ⟹   NP_001013099
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8333,938,226 - 33,951,613 (+)NCBI
mRatBN7.2313,540,409 - 13,553,796 (+)NCBI
Rnor_6.038,832,740 - 8,846,125 (+)NCBI
Rnor_5.0314,182,617 - 14,199,076 (+)NCBI
RGSC_v3.439,310,513 - 9,325,611 (+)RGD
Celera38,306,974 - 8,320,347 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233777   ⟹   XP_006233839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8333,935,291 - 33,951,614 (+)NCBI
mRatBN7.2313,537,452 - 13,553,797 (+)NCBI
Rnor_6.038,829,795 - 8,846,126 (+)NCBI
Rnor_5.0314,182,617 - 14,199,076 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233779   ⟹   XP_006233841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8333,937,510 - 33,951,614 (+)NCBI
mRatBN7.2313,539,158 - 13,553,797 (+)NCBI
Rnor_6.038,831,422 - 8,846,126 (+)NCBI
Rnor_5.0314,182,617 - 14,199,076 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591649   ⟹   XP_017447138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8333,933,487 - 33,951,614 (+)NCBI
mRatBN7.2313,535,670 - 13,553,797 (+)NCBI
Rnor_6.038,828,052 - 8,846,126 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001013099   ⟸   NM_001013081
- UniProtKB: Q5BJP9 (UniProtKB/Swiss-Prot),   A6JTW5 (UniProtKB/TrEMBL),   A0A8I6AEE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233839   ⟸   XM_006233777
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QBX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233841   ⟸   XM_006233779
- Peptide Label: isoform X2
- UniProtKB: Q5BJP9 (UniProtKB/Swiss-Prot),   A6JTW5 (UniProtKB/TrEMBL),   A0A8I6AEE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447138   ⟸   XM_017591649
- Peptide Label: isoform X2
- UniProtKB: Q5BJP9 (UniProtKB/Swiss-Prot),   A6JTW5 (UniProtKB/TrEMBL),   A0A8I6AEE4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022552   ⟸   ENSRNOT00000022552
Ensembl Acc Id: ENSRNOP00000093539   ⟸   ENSRNOT00000095142
Ensembl Acc Id: ENSRNOP00000090750   ⟸   ENSRNOT00000112840
Ensembl Acc Id: ENSRNOP00000110843   ⟸   ENSRNOT00000139700

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BJP9-F1-model_v2 AlphaFold Q5BJP9 1-291 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691955
Promoter ID:EPDNEW_R2479
Type:initiation region
Name:Phyhd1_1
Description:phytanoyl-CoA dioxygenase domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.038,832,681 - 8,832,741EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310377 AgrOrtholog
BioCyc Gene G2FUF-50226 BioCyc
BioCyc Pathway PWY66-387 [3-methyl-branched fatty acid alpha-oxidation] BioCyc
BioCyc Pathway Image PWY66-387 BioCyc
Ensembl Genes ENSRNOG00000016794 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000022552 ENTREZGENE
  ENSRNOT00000112840 ENTREZGENE
Gene3D-CATH q2cbj1_9rhob like domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7321523 IMAGE-MGC_LOAD
InterPro Phytyl_CoA_dOase UniProtKB/Swiss-Prot
KEGG Report rno:296621 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109475 IMAGE-MGC_LOAD
NCBI Gene 296621 ENTREZGENE
PANTHER PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 UniProtKB/Swiss-Prot
  PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot
Pfam PhyH UniProtKB/Swiss-Prot
PhenoGen Phyhd1 PhenoGen
RatGTEx ENSRNOG00000016794 RatGTEx
Superfamily-SCOP Clavaminate synthase-like UniProtKB/Swiss-Prot
UniProt A0A8I6AEE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AK09_RAT UniProtKB/TrEMBL
  A0A8L2QBX0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LZR4_RAT UniProtKB/TrEMBL
  A6JTW5 ENTREZGENE, UniProtKB/TrEMBL
  A6JTW6_RAT UniProtKB/TrEMBL
  A6JTW7_RAT UniProtKB/TrEMBL
  A6JTW8_RAT UniProtKB/TrEMBL
  PHYD1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Phyhd1  phytanoyl-CoA dioxygenase domain containing 1  Phyhd1_predicted  phytanoyl-CoA dioxygenase domain containing 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Phyhd1_predicted  phytanoyl-CoA dioxygenase domain containing 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED