Gene: Arhgef39 (Rho guanine nucleotide exchange factor 39) Rattus norvegicus
Analyze
Symbol:
Arhgef39
Name:
Rho guanine nucleotide exchange factor 39
RGD ID:
1310376
Description:
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of cell migration. Predicted to be active in plasma membrane. Orthologous to human ARHGEF39 (Rho guanine nucleotide exchange factor 39); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
hypothetical protein LOC298404; LOC298404; RGD1310376; Rho guanine nucleotide exchange factor (GEF) 39; similar to hypothetical protein FLJ14642; vav-like protein C9orf100 homolog
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ARHGEF39 (Rho guanine nucleotide exchange factor 39)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Arhgef39 (Rho guanine nucleotide exchange factor 39)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Arhgef39 (Rho guanine nucleotide exchange factor 39)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ARHGEF39 (Rho guanine nucleotide exchange factor 39)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ARHGEF39 (Rho guanine nucleotide exchange factor 39)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Arhgef39 (Rho guanine nucleotide exchange factor 39)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ARHGEF39 (Rho guanine nucleotide exchange factor 39)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
ARHGEF39 (Rho guanine nucleotide exchange factor 39)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Arhgef39 (Rho guanine nucleotide exchange factor 39)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Arhgef39 (Rho guanine nucleotide exchange factor 39)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
MED25 (mediator complex subunit 25)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
ARHGEF39 (Rho guanine nucleotide exchange factor 39)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Arhgef39 (Rho guanine nucleotide exchange factor 39)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
arhgef39 (Rho guanine nucleotide exchange factor (GEF) 39)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
RhoGEF4
Alliance
DIOPT (OrthoFinder|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
arhgef39
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 5 62,548,300 - 62,551,870 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 5 62,548,303 - 62,551,870 (-) Ensembl GRCr8 mRatBN7.2 5 57,752,509 - 57,756,079 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 5 57,752,509 - 57,756,109 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 5 59,732,391 - 59,735,965 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 5 61,551,204 - 61,554,778 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 5 61,522,655 - 61,526,213 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 5 58,998,209 - 59,001,779 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 5 58,995,249 - 59,001,800 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 5 63,522,803 - 63,526,373 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 5 59,977,497 - 59,979,258 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 5 56,333,084 - 56,336,654 (-) NCBI Celera RGSC_v3.1 5 59,976,596 - 59,979,421 (-) NCBI Cytogenetic Map 5 q22 NCBI
JBrowse:
Imported Disease Annotations - CTD
Only show annotations with direct experimental evidence (0 objects hidden)
Arhgef39 Rat (1->4)-beta-D-glucan multiple interactions ISO Arhgef39 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ARHGEF39 mRNA CTD PMID:36331819 Arhgef39 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Arhgef39 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Arhgef39 Rat 17beta-estradiol multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 Estradiol promotes the reaction [ESR2 protein affects the expression of ARHGEF39 mRNA] CTD PMID:20404318 Arhgef39 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Arhgef39 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Arhgef39 Rat 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 2,2',4,4'-tetrabromodiphenyl ether analog results in decreased expression of ARHGEF39 mRNA CTD PMID:19095052 Arhgef39 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Arhgef39 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Arhgef39 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in decreased expression of ARHGEF39 mRNA CTD PMID:29704546 Arhgef39 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ARHGEF39 mRNA CTD PMID:33387578 Arhgef39 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Arhgef39 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Arhgef39 Rat 4,4'-sulfonyldiphenol decreases expression ISO Arhgef39 (Mus musculus) 6480464 bisphenol S results in decreased expression of ARHGEF39 mRNA CTD PMID:39298647 Arhgef39 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ARHGEF39 mRNA CTD PMID:24780913 Arhgef39 Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of ARHGEF39 mRNA CTD PMID:31881176 Arhgef39 Rat antirheumatic drug decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of ARHGEF39 mRNA CTD PMID:24449571 Arhgef39 Rat aristolochic acid A decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of ARHGEF39 mRNA CTD PMID:33212167 Arhgef39 Rat arsane multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Arhgef39 Rat arsenic atom multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Arhgef39 Rat benzo[a]pyrene decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of ARHGEF39 mRNA CTD PMID:26238291 Arhgef39 Rat benzo[a]pyrene increases expression ISO Arhgef39 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of ARHGEF39 mRNA CTD PMID:32417428 Arhgef39 Rat benzo[a]pyrene diol epoxide I decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ARHGEF39 mRNA CTD PMID:26238291 Arhgef39 Rat beta-lapachone decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 beta-lapachone results in decreased expression of ARHGEF39 mRNA CTD PMID:38218311 Arhgef39 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ARHGEF39 mRNA CTD PMID:25181051|PMID:30816183|PMID:32528016 Arhgef39 Rat bisphenol A multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ARHGEF39 gene CTD PMID:31601247 Arhgef39 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ARHGEF39 mRNA CTD PMID:34947998 Arhgef39 Rat cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of ARHGEF39 mRNA CTD PMID:33453195 Arhgef39 Rat cadmium dichloride decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of ARHGEF39 mRNA CTD PMID:38568856 Arhgef39 Rat calcitriol multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of ARHGEF39 mRNA CTD PMID:21592394 Arhgef39 Rat calcitriol decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Calcitriol results in decreased expression of ARHGEF39 mRNA CTD PMID:21592394 Arhgef39 Rat copper(II) sulfate decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of ARHGEF39 mRNA CTD PMID:19549813 Arhgef39 Rat coumestrol increases expression ISO ARHGEF39 (Homo sapiens) 6480464 Coumestrol results in increased expression of ARHGEF39 mRNA CTD PMID:19167446 Arhgef39 Rat cyclosporin A decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ARHGEF39 mRNA CTD PMID:21632981 Arhgef39 Rat DDE increases expression ISO ARHGEF39 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of ARHGEF39 mRNA CTD PMID:38568856 Arhgef39 Rat Dibutyl phosphate affects expression ISO ARHGEF39 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of ARHGEF39 mRNA CTD PMID:37042841 Arhgef39 Rat dioxygen decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of ARHGEF39 mRNA CTD PMID:26516004 Arhgef39 Rat ethyl methanesulfonate increases expression ISO ARHGEF39 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of ARHGEF39 mRNA CTD PMID:23649840 Arhgef39 Rat formaldehyde increases expression ISO ARHGEF39 (Homo sapiens) 6480464 Formaldehyde results in increased expression of ARHGEF39 mRNA CTD PMID:23649840 Arhgef39 Rat fulvestrant multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ARHGEF39 gene CTD PMID:31601247 Arhgef39 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of ARHGEF39 mRNA CTD PMID:33387578 Arhgef39 Rat hydrogen peroxide affects expression ISO ARHGEF39 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of ARHGEF39 mRNA CTD PMID:20044591 Arhgef39 Rat irinotecan decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Irinotecan analog results in decreased expression of ARHGEF39 mRNA CTD PMID:18927307 Arhgef39 Rat leflunomide decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 leflunomide results in decreased expression of ARHGEF39 mRNA CTD PMID:28988120 Arhgef39 Rat manganese atom multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Arhgef39 Rat manganese(0) multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Arhgef39 Rat manganese(II) chloride multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Arhgef39 Rat methyl methanesulfonate increases expression ISO ARHGEF39 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of ARHGEF39 mRNA CTD PMID:23649840 Arhgef39 Rat methylmercury chloride decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of ARHGEF39 mRNA CTD PMID:28001369 Arhgef39 Rat N-Nitrosopyrrolidine decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in decreased expression of ARHGEF39 mRNA CTD PMID:32234424 Arhgef39 Rat okadaic acid increases expression ISO ARHGEF39 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of ARHGEF39 mRNA CTD PMID:38832940 Arhgef39 Rat ozone multiple interactions ISO Arhgef39 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... CTD PMID:34911549 Arhgef39 Rat ozone multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of ARHGEF39 mRNA CTD PMID:35430440 Arhgef39 Rat paracetamol decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ARHGEF39 mRNA CTD PMID:29067470 Arhgef39 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of ARHGEF39 mRNA CTD PMID:33387578 Arhgef39 Rat PCB138 multiple interactions ISO Arhgef39 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Arhgef39 Rat perfluorononanoic acid decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of ARHGEF39 mRNA CTD PMID:32588087 Arhgef39 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Arhgef39 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ARHGEF39 mRNA CTD PMID:36331819 Arhgef39 Rat resveratrol multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of ARHGEF39 mRNA CTD PMID:23557933 Arhgef39 Rat Rutecarpine decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 rutecarpine results in decreased expression of ARHGEF39 mRNA CTD PMID:34955744 Arhgef39 Rat silicon dioxide decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of ARHGEF39 mRNA CTD PMID:23806026 Arhgef39 Rat silver atom decreases expression ISO Arhgef39 (Mus musculus) 6480464 Silver results in decreased expression of ARHGEF39 mRNA CTD PMID:27131904 Arhgef39 Rat silver(0) decreases expression ISO Arhgef39 (Mus musculus) 6480464 Silver results in decreased expression of ARHGEF39 mRNA CTD PMID:27131904 Arhgef39 Rat sodium arsenate increases expression ISO Arhgef39 (Mus musculus) 6480464 sodium arsenate results in increased expression of ARHGEF39 mRNA CTD PMID:39847705 Arhgef39 Rat sodium arsenite increases expression ISO ARHGEF39 (Homo sapiens) 6480464 sodium arsenite results in increased expression of ARHGEF39 mRNA CTD PMID:29301061 Arhgef39 Rat sodium arsenite multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Arhgef39 Rat sodium arsenite affects expression ISO ARHGEF39 (Homo sapiens) 6480464 sodium arsenite affects the expression of ARHGEF39 mRNA CTD PMID:34032870 Arhgef39 Rat sodium arsenite decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of ARHGEF39 mRNA CTD PMID:38568856 Arhgef39 Rat sodium fluoride increases expression ISO Arhgef39 (Mus musculus) 6480464 Sodium Fluoride results in increased expression of ARHGEF39 mRNA CTD PMID:27862939 Arhgef39 Rat sulforaphane increases expression ISO ARHGEF39 (Homo sapiens) 6480464 sulforaphane results in increased expression of ARHGEF39 mRNA CTD PMID:31838189 Arhgef39 Rat sunitinib decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Sunitinib results in decreased expression of ARHGEF39 mRNA CTD PMID:31533062 Arhgef39 Rat testosterone multiple interactions ISO ARHGEF39 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of ARHGEF39 mRNA CTD PMID:21592394 Arhgef39 Rat testosterone decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Testosterone results in decreased expression of ARHGEF39 mRNA CTD PMID:21592394 Arhgef39 Rat tetrachloromethane increases expression ISO Arhgef39 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of ARHGEF39 mRNA CTD PMID:31919559 Arhgef39 Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of ARHGEF39 mRNA CTD PMID:34492290 Arhgef39 Rat thiram decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Thiram results in decreased expression of ARHGEF39 mRNA CTD PMID:38568856 Arhgef39 Rat trichloroethene increases expression ISO Arhgef39 (Mus musculus) 6480464 Trichloroethylene results in increased expression of ARHGEF39 mRNA CTD PMID:25549359 Arhgef39 Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of ARHGEF39 mRNA CTD PMID:33387578 Arhgef39 Rat trichostatin A affects expression ISO ARHGEF39 (Homo sapiens) 6480464 trichostatin A affects the expression of ARHGEF39 mRNA CTD PMID:28542535 Arhgef39 Rat triptonide decreases expression ISO Arhgef39 (Mus musculus) 6480464 triptonide results in decreased expression of ARHGEF39 mRNA CTD PMID:33045310 Arhgef39 Rat trovafloxacin decreases expression ISO Arhgef39 (Mus musculus) 6480464 trovafloxacin results in decreased expression of ARHGEF39 mRNA CTD PMID:35537566 Arhgef39 Rat valproic acid decreases expression ISO ARHGEF39 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ARHGEF39 mRNA CTD PMID:28001369