Pcdhb22 (protocadherin beta 22) - Rat Genome Database

Name: Pcdhb22
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Pcdhb22 (protocadherin beta 22) Rattus norvegicus

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Symbol:

Pcdhb22

Name:

protocadherin beta 22

RGD ID:

1310328

Description:

Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be located in photoreceptor connecting cilium. Predicted to be active in plasma membrane. Orthologous to human PCDHB15 (protocadherin beta 15); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC307486; pcdh-T5; protocadherin beta-15; protocadherin-T5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PCDHB15 (protocadherin beta 15)	HGNC	EggNOG, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Pcdhb22 (protocadherin beta 22)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOC100987426 (protocadherin beta-15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LOC487178 (protocadherin beta-15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LOC100514339 (protocadherin beta-2-like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PCDHB15 (protocadherin beta 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PCDHB15 (protocadherin beta 15)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pcdhb22 (protocadherin beta 22)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pcdh2g10 (protocadherin 2 gamma 10)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pcdh1g1 (protocadherin 1 gamma 1)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pcdh1g2 (protocadherin 1 gamma 2)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pcdh2g17 (protocadherin 2 gamma 17)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pcdh1g18 (protocadherin 1 gamma 18)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pcdh1g11 (protocadherin 1 gamma 11)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pcdh1g3 (protocadherin 1 gamma 3)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pcdh1gb2 (protocadherin 1 gamma b 2)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pcdh1gb9 (protocadherin 1 gamma b 9)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Cad96Cb	Alliance	DIOPT (InParanoid\|OMA)
Danio rerio (zebrafish):	pcdh1g14	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pcdh1g13	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	29,497,038 - 29,503,142 (+)	NCBI		GRCr8
mRatBN7.2	18	29,223,028 - 29,229,132 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	29,223,149 - 29,225,536 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	18	30,590,864 - 30,595,456 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	30,592,794 - 30,595,181 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	30,298,048 - 30,302,651 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	30,327,386 - 30,330,048 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	30,354,031 - 30,356,418 (+)	NCBI
Celera	18	28,918,568 - 28,921,569 (+)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant intellectual developmental disorder 31 (ISO)

familial adenomatous polyposis 1 (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-diaminotoluene (ISO)

2,6-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP)

bisphenol F (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

folic acid (ISO)

gentamycin (EXP)

L-methionine (ISO)

lead(0) (ISO)

manganese(II) chloride (EXP)

methotrexate (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

SB 431542 (ISO)

sodium fluoride (ISO)

sunitinib (ISO)

trichloroethene (EXP)

triptonide (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IBA)

homophilic cell adhesion via plasma membrane adhesion molecules (IEA)

Cellular Component

photoreceptor connecting cilium (ISO)

plasma membrane (IBA)

Molecular Function

calcium ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Multiple cadherin superfamily members with unique expression profiles are produced in rat testis.	Johnson KJ, etal., Endocrinology 2000 Feb;141(2):675-83.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.	Zhang T, etal., Genome Res 2004 Jan;14(1):79-89. Epub 2003 Dec 12.

Additional References at PubMed

PMID:15744052	PMID:18279309

Genomics

Comparative Map Data

Pcdhb22
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	29,497,038 - 29,503,142 (+)	NCBI		GRCr8
mRatBN7.2	18	29,223,028 - 29,229,132 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	29,223,149 - 29,225,536 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	18	30,590,864 - 30,595,456 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	30,592,794 - 30,595,181 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	30,298,048 - 30,302,651 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	30,327,386 - 30,330,048 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	30,354,031 - 30,356,418 (+)	NCBI
Celera	18	28,918,568 - 28,921,569 (+)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

PCDHB15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	141,245,395 - 141,249,365 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	141,245,395 - 141,249,365 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	140,624,963 - 140,628,933 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	140,605,331 - 140,607,986 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	140,605,330 - 140,607,983	NCBI
Celera	5	136,701,975 - 136,704,630 (+)	NCBI		Celera
Cytogenetic Map	5	q31.3	NCBI
HuRef	5	135,770,205 - 135,772,860 (+)	NCBI		HuRef
CHM1_1	5	140,058,351 - 140,061,006 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	141,770,701 - 141,774,671 (+)	NCBI		T2T-CHM13v2.0

Pcdhb22
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	37,651,402 - 37,657,532 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	37,650,924 - 37,657,532 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	37,518,353 - 37,521,419 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	37,517,871 - 37,524,479 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	37,678,007 - 37,681,073 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	37,644,327 - 37,647,393 (+)	NCBI		MGSCv36	mm8
Celera	18	38,869,674 - 38,872,740 (+)	NCBI		Celera
Cytogenetic Map	18	B3	NCBI
cM Map	18	19.51	NCBI

LOC100987426
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	136,490,132 - 136,499,118 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	134,629,915 - 134,638,670 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	136,605,233 - 136,611,147 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	142,721,180 - 142,724,785 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	142,721,472 - 142,723,835 (+)	Ensembl	panpan1.1		panPan2

LOC487178
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	36,251,313 - 36,271,637 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	33,302,959 - 33,323,542 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	36,705,659 - 36,716,774 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	36,705,911 - 36,710,593 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	33,779,722 - 33,800,301 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	34,590,711 - 34,611,298 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	35,398,365 - 35,418,957 (+)	NCBI		UU_Cfam_GSD_1.0

LOC100514339
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	2	142,803,760 - 142,808,886 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	148,873,511 - 148,888,495 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PCDHB15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	43,866,100 - 43,877,344 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	43,866,966 - 43,869,329 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	33,979,915 - 33,988,150 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Pcdhb22
14 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	16
Count of miRNA genes:	16
Interacting mature miRNAs:	16
Transcripts:	ENSRNOT00000027133
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	24796977	79788953	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	11944299	59330563	Rat
1331735	Rf44	Renal function QTL 44	2.981		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	18	18234564	31359530	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11941791	31393320	Rat
2301413	Bp318	Blood pressure QTL 318		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	26548082	46969551	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	21372893	83213037	Rat
61388	Bp2	Blood pressure QTL 2	3.23		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	1	35374722	Rat
6903359	Bp355	Blood pressure QTL 355	3.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944544	59796478	Rat
12904668	Bw188	Body weight QTL 188		0.03	body mass (VT:0001259)	body weight (CMO:0000012)	18	26548082	46969551	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	14951337	59951337	Rat
12904669	Cm125	Cardiac mass QTL 125		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	26548082	46969551	Rat
1641923	Colcr8	Colorectal carcinoma resistance QTL 8	3.1	0.0014	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	22066242	52293055	Rat
12904670	Cm126	Cardiac mass QTL 126		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	26548082	46969551	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5185858	40503530	Rat
2300157	Bmd66	Bone mineral density QTL 66	13.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
12904677	Kidm72	Kidney mass QTL 72		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	26548082	46969551	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944299	31359530	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	18007599	63571040	Rat
12904673	Cm127	Cardiac mass QTL 127		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	26548082	46969551	Rat
12904675	Am19	Aortic mass QTL 19		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	26548082	46969551	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	11941791	31393320	Rat
2293704	Bss35	Bone structure and strength QTL 35	4.59	0.0002	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	18	28964853	73964853	Rat
1331775	Bp235	Blood pressure QTL 235	3.201		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	18234564	31359530	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25570985	70570985	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19278901	83218561	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
2300177	Bmd65	Bone mineral density QTL 65	19.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
9589153	Insul31	Insulin level QTL 31	7.15	0.05	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	18	1	42547119	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	30558703	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34291613	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4207941	60377792	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944299	52293055	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34291613	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	11944299	41122201	Rat

Markers in Region

RH134768

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	29,225,526 - 29,225,738 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	30,595,172 - 30,595,383	NCBI	Rnor6.0
Rnor_5.0	18	30,302,367 - 30,302,578	UniSTS	Rnor5.0
RGSC_v3.4	18	30,329,764 - 30,329,975	UniSTS	RGSC3.4
Celera	18	28,921,285 - 28,921,496	UniSTS
RH 3.4 Map	18	422.4	UniSTS
Cytogenetic Map	18	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	89	88	57	25	57	6	216	97	93	45	59	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001416815	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001056235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001065549	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC131360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF177699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027133 ⟹ ENSRNOP00000027133

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	29,223,149 - 29,225,536 (+)	Ensembl
Rnor_6.0 Ensembl	18	30,592,794 - 30,595,181 (+)	Ensembl

RefSeq Acc Id:

NM_001416815 ⟹ NP_001403744

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	29,497,038 - 29,503,142 (+)	NCBI
mRatBN7.2	18	29,223,028 - 29,229,132 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001403744	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF87074	(Get FASTA)	NCBI Sequence Viewer
	EDL76360	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027133.1

Ensembl Acc Id:

ENSRNOP00000027133 ⟸ ENSRNOT00000027133

RefSeq Acc Id:	NP_001403744 ⟸ NM_001416815
- UniProtKB:	G3V8N1 (UniProtKB/TrEMBL), A6J378 (UniProtKB/TrEMBL)

Protein Domains

Cadherin

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V8N1-F1-model_v2	AlphaFold	G3V8N1	1-795	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310328	AgrOrtholog
Ensembl Genes	ENSRNOG00000020028	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000027133.3	UniProtKB/TrEMBL
Gene3D-CATH	Cadherins	UniProtKB/TrEMBL
InterPro	Cadherin	UniProtKB/TrEMBL
	Cadherin-like	UniProtKB/TrEMBL
	Cadherin_C	UniProtKB/TrEMBL
	Cadherin_CS	UniProtKB/TrEMBL
	Cadherin_N	UniProtKB/TrEMBL
	Protocadherin/Cadherin-CA	UniProtKB/TrEMBL
NCBI Gene	307486	ENTREZGENE
PANTHER	CADHERIN-87A	UniProtKB/TrEMBL
	PTHR24028:SF97	UniProtKB/TrEMBL
Pfam	Cadherin	UniProtKB/TrEMBL
	Cadherin_2	UniProtKB/TrEMBL
	Cadherin_C_2	UniProtKB/TrEMBL
PhenoGen	Pcdhb22	PhenoGen
PRINTS	CADHERIN	UniProtKB/TrEMBL
PROSITE	CADHERIN_1	UniProtKB/TrEMBL
	CADHERIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000020028	RatGTEx
SMART	SM00112	UniProtKB/TrEMBL
Superfamily-SCOP	Cadherin	UniProtKB/TrEMBL
UniProt	A6J378	ENTREZGENE, UniProtKB/TrEMBL
	G3V8N1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Pcdhb22	protocadherin beta 22	Pcdhb22_predicted	protocadherin beta 22 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Pcdhb22_predicted	protocadherin beta 22 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar