Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Chchd3 | Rat | 1,2-dichloroethane | increases expression | ISO | Chchd3 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of CHCHD3 mRNA | CTD | PMID:28960355 | Chchd3 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Chchd3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD3 mRNA | CTD | PMID:22206623 | Chchd3 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of CHCHD3 mRNA | CTD | PMID:22206623 | Chchd3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CHCHD3 mRNA | CTD | PMID:33387578 | Chchd3 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of CHCHD3 mRNA | CTD | PMID:21346803 | Chchd3 | Rat | 2-methylcholine | affects expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of CHCHD3 mRNA | CTD | PMID:21179406 | Chchd3 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Chchd3 (Mus musculus) | 6480464 | bisphenol S results in increased expression of CHCHD3 mRNA | CTD | PMID:39298647 | Chchd3 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of CHCHD3 protein | CTD | PMID:34186270 | Chchd3 | Rat | 4,4'-sulfonyldiphenol | affects expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | bisphenol S affects the expression of CHCHD3 protein | CTD | PMID:31945527 | Chchd3 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Decitabine affects the expression of CHCHD3 mRNA | CTD | PMID:23300844 | Chchd3 | Rat | acrolein | multiple interactions | ISO | CHCHD3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Chchd3 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CHCHD3 mRNA | CTD | PMID:28959563 | Chchd3 | Rat | aflatoxin B1 | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of CHCHD3 mRNA | CTD | PMID:19770486 | Chchd3 | Rat | all-trans-retinoic acid | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of CHCHD3 mRNA | CTD | PMID:33167477 | Chchd3 | Rat | alpha-pinene | multiple interactions | ISO | CHCHD3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Chchd3 | Rat | antirheumatic drug | increases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of CHCHD3 mRNA | CTD | PMID:24449571 | Chchd3 | Rat | arsane | multiple interactions | ISO | CHCHD3 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of CHCHD3 more ... | CTD | PMID:32525701|PMID:39836092 | Chchd3 | Rat | arsenic atom | multiple interactions | ISO | CHCHD3 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of CHCHD3 more ... | CTD | PMID:32525701|PMID:39836092 | Chchd3 | Rat | arsenite(3-) | multiple interactions | ISO | CHCHD3 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to CHCHD3 mRNA] | CTD | PMID:32406909 | Chchd3 | Rat | atrazine | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of CHCHD3 mRNA | CTD | PMID:22378314 | Chchd3 | Rat | benzo[a]pyrene | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of CHCHD3 mRNA | CTD | PMID:21715664 | Chchd3 | Rat | benzo[a]pyrene | increases methylation | ISO | Chchd3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of CHCHD3 intron | CTD | PMID:27901495 | Chchd3 | Rat | benzo[a]pyrene | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of CHCHD3 mRNA | CTD | PMID:20064835|PMID:20106945|PMID:21632981 | Chchd3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CHCHD3 mRNA | CTD | PMID:25181051 | Chchd3 | Rat | bisphenol A | increases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of CHCHD3 protein | CTD | PMID:37567409 | Chchd3 | Rat | bisphenol A | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of CHCHD3 protein | CTD | PMID:34186270 | Chchd3 | Rat | bisphenol A | increases methylation | ISO | CHCHD3 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of CHCHD3 gene | CTD | PMID:31601247 | Chchd3 | Rat | bisphenol A | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of CHCHD3 mRNA | CTD | PMID:33221593 | Chchd3 | Rat | bisphenol AF | increases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of CHCHD3 protein | CTD | PMID:34186270 | Chchd3 | Rat | Bisphenol B | increases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of CHCHD3 protein | CTD | PMID:34186270 | Chchd3 | Rat | bisphenol F | increases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of CHCHD3 protein | CTD | PMID:34186270 | Chchd3 | Rat | cisplatin | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of CHCHD3 mRNA | CTD | PMID:19561079|PMID:24280081|PMID:27392435 | Chchd3 | Rat | cisplatin | affects expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Cisplatin affects the expression of CHCHD3 mRNA | CTD | PMID:23300844 | Chchd3 | Rat | cisplatin | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | Cisplatin results in decreased expression of CHCHD3 mRNA | CTD | PMID:24280081 | Chchd3 | Rat | clofibrate | multiple interactions | ISO | Chchd3 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of CHCHD3 mRNA; PPARA affects the reaction [[Clofibrate more ... | CTD | PMID:17585979 | Chchd3 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CHCHD3 mRNA | CTD | PMID:17602206 | Chchd3 | Rat | coumarin | increases phosphorylation | ISO | CHCHD3 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of CHCHD3 protein | CTD | PMID:35688186 | Chchd3 | Rat | cyclosporin A | increases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of CHCHD3 mRNA | CTD | PMID:20106945 | Chchd3 | Rat | Dibutyl phosphate | affects expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of CHCHD3 mRNA | CTD | PMID:37042841 | Chchd3 | Rat | dibutyl phthalate | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of CHCHD3 mRNA | CTD | PMID:21266533 | Chchd3 | Rat | dimethyl sulfoxide | increases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Dimethyl Sulfoxide results in increased expression of CHCHD3 mRNA | CTD | PMID:39709020 | Chchd3 | Rat | doxorubicin | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of CHCHD3 mRNA | CTD | PMID:29803840 | Chchd3 | Rat | enzyme inhibitor | multiple interactions | ISO | CHCHD3 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Chchd3 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of CHCHD3 mRNA | CTD | PMID:24136188 | Chchd3 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of CHCHD3 mRNA | CTD | PMID:24136188 | Chchd3 | Rat | folic acid | multiple interactions | ISO | Chchd3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD3 mRNA | CTD | PMID:22206623 | Chchd3 | Rat | folic acid | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of CHCHD3 mRNA | CTD | PMID:25629700 | Chchd3 | Rat | FR900359 | increases phosphorylation | ISO | CHCHD3 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of CHCHD3 protein | CTD | PMID:37730182 | Chchd3 | Rat | hexadecanoic acid | increases phosphorylation | ISO | CHCHD3 (Homo sapiens) | 6480464 | Palmitic Acid results in increased phosphorylation of CHCHD3 protein | CTD | PMID:28073184 | Chchd3 | Rat | hydroxyurea | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | Hydroxyurea results in decreased expression of CHCHD3 mRNA | CTD | PMID:12929121 | Chchd3 | Rat | ivermectin | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of CHCHD3 protein | CTD | PMID:32959892 | Chchd3 | Rat | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of CHCHD3 mRNA | CTD | PMID:24136188 | Chchd3 | Rat | methidathion | increases expression | ISO | Chchd3 (Mus musculus) | 6480464 | methidathion results in increased expression of CHCHD3 mRNA | CTD | PMID:34813904 | Chchd3 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CHCHD3 mRNA | CTD | PMID:17602206 | Chchd3 | Rat | okadaic acid | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of CHCHD3 protein | CTD | PMID:19397276 | Chchd3 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of CHCHD3 mRNA | CTD | PMID:25729387 | Chchd3 | Rat | ozone | multiple interactions | ISO | CHCHD3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Chchd3 | Rat | p-anisidine | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | 4-anisidine results in decreased expression of CHCHD3 mRNA | CTD | PMID:12929121 | Chchd3 | Rat | paclitaxel | decreases expression | ISO | Chchd3 (Mus musculus) | 6480464 | Paclitaxel results in decreased expression of CHCHD3 mRNA | CTD | PMID:12929121 | Chchd3 | Rat | paracetamol | multiple interactions | ISO | Chchd3 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of CHCHD3 mRNA; PPARA affects the reaction [[Clofibrate more ... | CTD | PMID:17585979 | Chchd3 | Rat | paracetamol | affects expression | ISO | Chchd3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of CHCHD3 mRNA | CTD | PMID:17562736 | Chchd3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Chchd3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of CHCHD3 mRNA | CTD | PMID:36331819 | Chchd3 | Rat | pirinixic acid | increases expression | ISO | Chchd3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of CHCHD3 mRNA | CTD | PMID:18301758 | Chchd3 | Rat | resveratrol | increases expression | ISO | Chchd3 (Mus musculus) | 6480464 | resveratrol results in increased expression of CHCHD3 protein | CTD | PMID:25505154 | Chchd3 | Rat | sodium arsenate | multiple interactions | ISO | CHCHD3 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of CHCHD3 more ... | CTD | PMID:32525701 | Chchd3 | Rat | sodium arsenite | multiple interactions | ISO | CHCHD3 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CHCHD3 more ... | CTD | PMID:33939924|PMID:39836092 | Chchd3 | Rat | sodium dichromate | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | sodium bichromate results in decreased expression of CHCHD3 mRNA | CTD | PMID:17685462 | Chchd3 | Rat | sulindac | decreases expression | EXP | | 6480464 | Sulindac results in decreased expression of CHCHD3 mRNA | CTD | PMID:24136188 | Chchd3 | Rat | temozolomide | decreases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of CHCHD3 mRNA | CTD | PMID:31758290 | Chchd3 | Rat | titanium dioxide | decreases methylation | ISO | Chchd3 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of CHCHD3 gene | CTD | PMID:35295148 | Chchd3 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of CHCHD3 mRNA | CTD | PMID:25729387 | Chchd3 | Rat | trimellitic anhydride | increases expression | ISO | Chchd3 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of CHCHD3 mRNA | CTD | PMID:19042947 | Chchd3 | Rat | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of CHCHD3 protein | CTD | PMID:32519852 | Chchd3 | Rat | triptonide | increases expression | ISO | Chchd3 (Mus musculus) | 6480464 | triptonide results in increased expression of CHCHD3 mRNA | CTD | PMID:33045310 | Chchd3 | Rat | valproic acid | increases expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CHCHD3 mRNA | CTD | PMID:23179753|PMID:29154799 | Chchd3 | Rat | valproic acid | affects expression | ISO | CHCHD3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CHCHD3 mRNA | CTD | PMID:25979313 | Chchd3 | Rat | zearalenone | increases expression | ISO | Chchd3 (Mus musculus) | 6480464 | Zearalenone results in increased expression of CHCHD3 protein | CTD | PMID:25058043 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















