Chchd3 (coiled-coil-helix-coiled-coil-helix domain containing 3) - Rat Genome Database

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Gene: Chchd3 (coiled-coil-helix-coiled-coil-helix domain containing 3) Rattus norvegicus
Analyze
Symbol: Chchd3
Name: coiled-coil-helix-coiled-coil-helix domain containing 3
RGD ID: 1310325
Description: Predicted to enable molecular adaptor activity and phosphatase binding activity. Predicted to be involved in cristae formation and mitochondrial fusion. Predicted to be located in mitochondrial inner membrane. Predicted to be part of MICOS complex. Orthologous to human CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3); PARTICIPATES IN mitochondrial protein import pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; LOC296966; MICOS complex subunit MIC19
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8462,327,574 - 62,584,085 (-)NCBIGRCr8
mRatBN7.2461,360,352 - 61,616,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl461,360,353 - 61,616,847 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx466,339,067 - 66,595,541 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0462,254,817 - 62,511,283 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0460,657,202 - 60,913,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0460,080,536 - 60,358,592 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl460,080,538 - 60,358,562 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0459,822,342 - 60,099,177 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4459,891,615 - 60,170,903 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1460,167,728 - 60,453,221 (-)NCBI
Celera456,445,848 - 56,700,814 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Chchd3Ratpleomorphic xanthoastrocytoma  ISOCHCHD3 (Homo sapiens)8554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Chchd3Ratsubstance-related disorder  ISOCHCHD3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20098672

1 to 20 of 76 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Chchd3Rat1,2-dichloroethane increases expressionISOChchd3 (Mus musculus)6480464ethylene dichloride results in increased expression of CHCHD3 mRNACTDPMID:28960355
Chchd3Rat1,2-dimethylhydrazine multiple interactionsISOChchd3 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHCHD3 mRNACTDPMID:22206623
Chchd3Rat1,2-dimethylhydrazine decreases expressionISOChchd3 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of CHCHD3 mRNACTDPMID:22206623
Chchd3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of CHCHD3 mRNACTDPMID:33387578
Chchd3Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of CHCHD3 mRNACTDPMID:21346803
Chchd3Rat2-methylcholine affects expressionISOCHCHD3 (Homo sapiens)6480464beta-methylcholine affects the expression of CHCHD3 mRNACTDPMID:21179406
Chchd3Rat4,4'-sulfonyldiphenol increases expressionISOChchd3 (Mus musculus)6480464bisphenol S results in increased expression of CHCHD3 mRNACTDPMID:39298647
Chchd3Rat4,4'-sulfonyldiphenol increases expressionISOCHCHD3 (Homo sapiens)6480464bisphenol S results in increased expression of CHCHD3 proteinCTDPMID:34186270
Chchd3Rat4,4'-sulfonyldiphenol affects expressionISOCHCHD3 (Homo sapiens)6480464bisphenol S affects the expression of CHCHD3 proteinCTDPMID:31945527
Chchd3Rat5-aza-2'-deoxycytidine affects expressionISOCHCHD3 (Homo sapiens)6480464Decitabine affects the expression of CHCHD3 mRNACTDPMID:23300844
Chchd3Ratacrolein multiple interactionsISOCHCHD3 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CHCHD3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of CHCHD3 mRNACTDPMID:32699268
Chchd3Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of CHCHD3 mRNACTDPMID:28959563
Chchd3Rataflatoxin B1 decreases expressionISOChchd3 (Mus musculus)6480464Aflatoxin B1 results in decreased expression of CHCHD3 mRNACTDPMID:19770486
Chchd3Ratall-trans-retinoic acid decreases expressionISOCHCHD3 (Homo sapiens)6480464Tretinoin results in decreased expression of CHCHD3 mRNACTDPMID:33167477
Chchd3Ratalpha-pinene multiple interactionsISOCHCHD3 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CHCHD3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of CHCHD3 mRNACTDPMID:32699268
Chchd3Ratantirheumatic drug increases expressionISOCHCHD3 (Homo sapiens)6480464Antirheumatic Agents results in increased expression of CHCHD3 mRNACTDPMID:24449571
Chchd3Ratarsane multiple interactionsISOCHCHD3 (Homo sapiens)6480464[sodium arsenate results in increased abundance of Arsenic] which results in increased expression of CHCHD3 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CHCHD3 mRNACTDPMID:32525701 and PMID:39836092
Chchd3Ratarsenic atom multiple interactionsISOCHCHD3 (Homo sapiens)6480464[sodium arsenate results in increased abundance of Arsenic] which results in increased expression of CHCHD3 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CHCHD3 mRNACTDPMID:32525701 and PMID:39836092
Chchd3Ratarsenite(3-) multiple interactionsISOCHCHD3 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to CHCHD3 mRNA]CTDPMID:32406909
Chchd3Ratatrazine decreases expressionISOCHCHD3 (Homo sapiens)6480464Atrazine results in decreased expression of CHCHD3 mRNACTDPMID:22378314

1 to 20 of 76 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Chchd3Ratbiological_process  ND 159840711/2017: no relevant rat dataRGD 
Chchd3Ratcristae formation involved_inISOCHCHD3 (Homo sapiens)1624291 PMID:25781180 more ...RGDPMID:25781180 more ...
Chchd3Ratcristae formation involved_inIEAUniProtKB:Q9NX63 and ensembl:ENSP000002625701600115GO_REF:0000107EnsemblGO_REF:0000107
Chchd3Ratinner mitochondrial membrane organization involved_inISOCHCHD3 (Homo sapiens)1624291 PMID:21081504RGDPMID:21081504
Chchd3Ratinner mitochondrial membrane organization involved_inIEAUniProtKB:Q9NX63 and ensembl:ENSP000002625701600115GO_REF:0000107EnsemblGO_REF:0000107
Chchd3Ratinner mitochondrial membrane organization involved_inIBAFB:FBgn0010808 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Chchd3Ratmitochondrial fusion involved_inISOCHCHD3 (Homo sapiens)1624291 PMID:21081504RGDPMID:21081504
Chchd3Ratmitochondrial fusion involved_inIEAUniProtKB:Q9NX63 and ensembl:ENSP000002625701600115GO_REF:0000107EnsemblGO_REF:0000107

Cellular Component
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Chchd3Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Chchd3RatMICOS complex part_ofISOCHCHD3 (Homo sapiens)1624291 PMID:25781180 and PMID:25997101RGDPMID:25781180 and PMID:25997101
Chchd3RatMICOS complex part_ofIEAUniProtKB:Q9NX63 and ensembl:ENSP000002625701600115GO_REF:0000107EnsemblGO_REF:0000107
Chchd3RatMICOS complex part_ofIEAInterPro:IPR0079641600115GO_REF:0000002InterProGO_REF:0000002
Chchd3RatMICOS complex part_ofIBAFB:FBgn0010808 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Chchd3Ratmitochondrial inner membrane located_inISOChchd3 (Mus musculus)1624291 PMID:21081504RGDPMID:21081504
Chchd3Ratmitochondrial inner membrane located_inIEAUniProtKB:Q9CRB9 and ensembl:ENSMUSP000000701491600115GO_REF:0000107EnsemblGO_REF:0000107
Chchd3Ratmitochondrial inner membrane located_inIEAUniProtKB-KW:KW-09991600115GO_REF:0000043UniProtGO_REF:0000043
Chchd3Ratmitochondrial inner membrane located_inIEAUniProtKB-SubCell:SL-01681600115GO_REF:0000044UniProtGO_REF:0000044
Chchd3Ratmitochondrion located_inISOCHCHD3 (Homo sapiens)1624291 PMID:25781180 and PMID:25997101RGDGO_REF:0000052 more ...
Chchd3Ratmitochondrion located_inIEAUniProtKB:Q9NX63 and ensembl:ENSP000002625701600115GO_REF:0000107EnsemblGO_REF:0000107
Chchd3Ratmitochondrion located_inIEAUniProtKB:A4D1N4 and ensembl:ENSP000002625701600115GO_REF:0000107EnsemblGO_REF:0000107
Chchd3Ratmitochondrion located_inISOChchd3 (Mus musculus)1624291 PMID:14651853RGDPMID:14651853
Chchd3Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
Chchd3Ratmitochondrion located_inIEAUniProtKB:Q9CRB9 and ensembl:ENSMUSP000000701491600115GO_REF:0000107EnsemblGO_REF:0000107
Chchd3Ratmitochondrion located_inIEAInterPro:IPR0079641600115GO_REF:0000002InterProGO_REF:0000002
1 to 16 of 16 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Chchd3Ratmitochondrial protein import pathway  contributes_toISOCHCHD3 (Homo sapiens)10412671 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Mitofilin complexes: conserved organizers of mitochondrial membrane architecture. Zerbes RM, etal., Biol Chem. 2012 Nov;393(11):1247-61. doi: 10.1515/hsz-2012-0239.
PMID:12865426   PMID:14651853   PMID:18614015   PMID:19056867   PMID:19389623   PMID:20833797   PMID:21081504   PMID:21700703   PMID:22567091   PMID:25002582   PMID:25781180   PMID:25997101  
PMID:35352799  



Chchd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8462,327,574 - 62,584,085 (-)NCBIGRCr8
mRatBN7.2461,360,352 - 61,616,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl461,360,353 - 61,616,847 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx466,339,067 - 66,595,541 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0462,254,817 - 62,511,283 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0460,657,202 - 60,913,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0460,080,536 - 60,358,592 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl460,080,538 - 60,358,562 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0459,822,342 - 60,099,177 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4459,891,615 - 60,170,903 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1460,167,728 - 60,453,221 (-)NCBI
Celera456,445,848 - 56,700,814 (-)NCBICelera
Cytogenetic Map4q22NCBI
CHCHD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387132,784,870 - 133,082,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7132,784,870 - 133,082,090 (-)EnsemblGRCh38hg38GRCh38
GRCh377132,469,631 - 132,766,850 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367132,120,163 - 132,417,373 (-)NCBINCBI36Build 36hg18NCBI36
Build 347131,926,878 - 132,224,083NCBI
Celera7127,221,897 - 127,518,382 (-)NCBICelera
Cytogenetic Map7q32.3-q33NCBI
HuRef7126,786,105 - 127,082,694 (-)NCBIHuRef
CHM1_17132,405,107 - 132,701,867 (-)NCBICHM1_1
T2T-CHM13v2.07134,106,386 - 134,403,617 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27131,809,095 - 132,106,393 (-)NCBI
Chchd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39632,769,142 - 33,037,206 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl632,767,911 - 33,037,195 (-)EnsemblGRCm39 Ensembl
GRCm38632,792,207 - 33,060,273 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl632,790,976 - 33,060,260 (-)EnsemblGRCm38mm10GRCm38
MGSCv37632,742,227 - 33,010,152 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36632,722,385 - 32,990,310 (-)NCBIMGSCv36mm8
Celera632,774,244 - 33,045,665 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map613.97NCBI
Chchd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541034,818,649 - 35,093,398 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541034,818,660 - 35,093,398 (+)NCBIChiLan1.0ChiLan1.0
CHCHD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26169,616,069 - 169,914,545 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1721,626,315 - 21,924,770 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07124,758,547 - 125,056,898 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17137,268,178 - 137,566,431 (-)NCBIpanpan1.1PanPan1.1panPan2
CHCHD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1144,229,860 - 4,507,987 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl144,229,870 - 4,612,884 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha143,891,447 - 4,169,469 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0143,967,947 - 4,245,811 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl143,967,948 - 4,275,036 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1144,170,426 - 4,448,557 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0143,916,616 - 4,194,720 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0144,057,569 - 4,335,764 (+)NCBIUU_Cfam_GSD_1.0
Chchd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511822,433,794 - 22,707,772 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365792,566,330 - 2,840,870 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365792,566,353 - 2,840,364 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHCHD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1816,052,627 - 16,350,974 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11816,052,611 - 16,348,998 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21817,408,462 - 17,410,929 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21817,086,333 - 17,353,549 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHCHD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121101,424,017 - 101,715,708 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660421,657,904 - 1,950,207 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chchd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247833,330,997 - 3,607,666 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247833,330,977 - 3,607,666 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Chchd3
738 total Variants

Predicted Target Of
Summary Value
Count of predictions:220
Count of miRNA genes:143
Interacting mature miRNAs:171
Transcripts:ENSRNOT00000018001
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 47 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)45664777678882945Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)45664777678882945Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45711443281266970Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat

1 to 10 of 47 rows
BF388181  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2461,606,246 - 61,606,453 (+)MAPPERmRatBN7.2
Rnor_6.0460,347,988 - 60,348,194NCBIRnor6.0
Rnor_5.0460,088,603 - 60,088,809UniSTSRnor5.0
RGSC_v3.4460,160,356 - 60,160,562UniSTSRGSC3.4
Celera456,690,237 - 56,690,443UniSTS
RH 3.4 Map4366.6UniSTS
Cytogenetic Map4q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000018001   ⟹   ENSRNOP00000018001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl461,360,353 - 61,616,826 (-)Ensembl
Rnor_6.0 Ensembl460,080,538 - 60,358,562 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095741   ⟹   ENSRNOP00000085835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl461,360,760 - 61,616,847 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107504   ⟹   ENSRNOP00000093797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl461,369,890 - 61,616,834 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107634   ⟹   ENSRNOP00000092148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl461,360,365 - 61,616,804 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117489   ⟹   ENSRNOP00000081053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl461,360,780 - 61,616,826 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119480   ⟹   ENSRNOP00000077614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl461,428,283 - 61,616,826 (-)Ensembl
RefSeq Acc Id: NM_001106588   ⟹   NP_001100058
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8462,327,576 - 62,584,033 (-)NCBI
mRatBN7.2461,360,354 - 61,616,821 (-)NCBI
Rnor_6.0460,080,538 - 60,358,562 (-)NCBI
Rnor_5.0459,822,342 - 60,099,177 (-)NCBI
RGSC_v3.4459,891,615 - 60,170,903 (-)RGD
Celera456,445,848 - 56,700,814 (-)RGD
Sequence:
RefSeq Acc Id: XM_017592525   ⟹   XP_017448014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8462,327,574 - 62,584,085 (-)NCBI
mRatBN7.2461,360,352 - 61,616,850 (-)NCBI
Rnor_6.0460,080,536 - 60,358,592 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592526   ⟹   XP_017448015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8462,327,574 - 62,584,085 (-)NCBI
mRatBN7.2461,360,352 - 61,616,850 (-)NCBI
Rnor_6.0460,080,536 - 60,358,592 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039107283   ⟹   XP_038963211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8462,327,574 - 62,431,346 (-)NCBI
mRatBN7.2461,360,352 - 61,464,116 (-)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_001100058   ⟸   NM_001106588
- UniProtKB: D3ZUX5 (UniProtKB/TrEMBL),   A6IEK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448015   ⟸   XM_017592526
- Peptide Label: isoform X2
- UniProtKB: D3ZUX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448014   ⟸   XM_017592525
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AD55 (UniProtKB/TrEMBL),   D3ZUX5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018001   ⟸   ENSRNOT00000018001
RefSeq Acc Id: XP_038963211   ⟸   XM_039107283
- Peptide Label: isoform X3

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZUX5-F1-model_v2 AlphaFold D3ZUX5 1-227 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692947
Promoter ID:EPDNEW_R3472
Type:initiation region
Name:Chchd3_1
Description:coiled-coil-helix-coiled-coil-helix domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0460,358,544 - 60,358,604EPDNEW


1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-45287 BioCyc
Ensembl Genes ENSRNOG00000013211 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018001 ENTREZGENE
  ENSRNOT00000018001.5 UniProtKB/TrEMBL
  ENSRNOT00000095741.1 UniProtKB/TrEMBL
  ENSRNOT00000107504.1 UniProtKB/TrEMBL
  ENSRNOT00000107634 ENTREZGENE
  ENSRNOT00000107634.1 UniProtKB/TrEMBL
  ENSRNOT00000117489.1 UniProtKB/TrEMBL
  ENSRNOT00000119480.1 UniProtKB/TrEMBL
InterPro MIC19/MIC25 UniProtKB/TrEMBL
  MICOS_subunit_Mic19 UniProtKB/TrEMBL
KEGG Report rno:296966 UniProtKB/TrEMBL
NCBI Gene 296966 ENTREZGENE
PANTHER COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 UniProtKB/TrEMBL
  MICOS COMPLEX SUBUNIT MIC19 UniProtKB/TrEMBL
Pfam MIC19_MIC25 UniProtKB/TrEMBL
PhenoGen Chchd3 PhenoGen
PROSITE CHCH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013211 RatGTEx
UniProt A0A8I5YCF6_RAT UniProtKB/TrEMBL
  A0A8I6A2D7_RAT UniProtKB/TrEMBL
  A0A8I6AD55 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AGG9_RAT UniProtKB/TrEMBL
  A0A8I6G7G6_RAT UniProtKB/TrEMBL
  A6IEK5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZUX5 ENTREZGENE, UniProtKB/TrEMBL
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Chchd3  coiled-coil-helix-coiled-coil-helix domain containing 3   Chchd3_predicted  coiled-coil-helix-coiled-coil-helix domain containing 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Chchd3_predicted  coiled-coil-helix-coiled-coil-helix domain containing 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED