Ap3b1 (adaptor related protein complex 3 subunit beta 1) - Rat Genome Database

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Gene: Ap3b1 (adaptor related protein complex 3 subunit beta 1) Rattus norvegicus
Analyze
Symbol: Ap3b1
Name: adaptor related protein complex 3 subunit beta 1
RGD ID: 1310256
Description: Predicted to enable GTP-dependent protein binding activity and protein phosphatase binding activity. Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Predicted to act upstream of with a positive effect on positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within with a negative effect on mRNA transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including antigen processing and presentation, exogenous lipid antigen via MHC class Ib; hemopoiesis; and vesicle organization. Predicted to be located in several cellular components, including Golgi apparatus; axon cytoplasm; and clathrin-coated vesicle membrane. Predicted to be part of AP-3 adaptor complex and clathrin adaptor complex. Predicted to be active in microvesicle. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome; Hermansky-Pudlak syndrome 2; interstitial lung disease; neutropenia; and pulmonary fibrosis. Orthologous to human AP3B1 (adaptor related protein complex 3 subunit beta 1); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adaptor-related protein complex 3, beta 1 subunit; AP-3 complex subunit beta-1; LOC309969
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8227,331,241 - 27,535,683 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl227,334,900 - 27,537,702 (+)EnsemblGRCr8
mRatBN7.2225,600,069 - 25,800,937 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl225,600,040 - 25,800,935 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx232,628,825 - 32,828,969 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0230,729,080 - 30,929,207 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0225,553,041 - 25,753,147 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0224,022,815 - 24,227,522 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl224,024,791 - 24,226,224 (+)Ensemblrn6Rnor6.0
Rnor_5.0243,195,152 - 43,397,102 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4224,670,078 - 24,872,770 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera221,672,156 - 21,872,572 (+)NCBICelera
RGSC_v3.1224,557,732 - 24,793,137 (+)NCBI
Cytogenetic Map2q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The Hermansky-Pudlak syndrome 1 (HPS1) and HPS2 genes independently contribute to the production and function of platelet dense granules, melanosomes, and lysosomes. Feng L, etal., Blood. 2002 Mar 1;99(5):1651-8.
2. Genomic structure of the mouse Ap3b1 gene in normal and pearl mice. Feng L, etal., Genomics. 2000 Nov 1;69(3):370-9.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Interstitial lung disease and pulmonary fibrosis in Hermansky-Pudlak syndrome type 2, an adaptor protein-3 complex disease. Gochuico BR, etal., Mol Med. 2012 Feb 10;18:56-64. doi: 10.2119/molmed.2011.00198.
6. Disorders of vesicles of lysosomal lineage: the Hermansky-Pudlak syndromes. Huizing M and Gahl WA, Curr Mol Med. 2002 Aug;2(5):451-67.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:6696991   PMID:9188501   PMID:9931340   PMID:11058094   PMID:11452004   PMID:11588176   PMID:12777251   PMID:14557411   PMID:17622474   PMID:17897319   PMID:19841138   PMID:19946888  
PMID:20847273   PMID:21998198   PMID:22511774   PMID:23146885   PMID:23748140  


Genomics

Comparative Map Data
Ap3b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8227,331,241 - 27,535,683 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl227,334,900 - 27,537,702 (+)EnsemblGRCr8
mRatBN7.2225,600,069 - 25,800,937 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl225,600,040 - 25,800,935 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx232,628,825 - 32,828,969 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0230,729,080 - 30,929,207 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0225,553,041 - 25,753,147 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0224,022,815 - 24,227,522 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl224,024,791 - 24,226,224 (+)Ensemblrn6Rnor6.0
Rnor_5.0243,195,152 - 43,397,102 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4224,670,078 - 24,872,770 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera221,672,156 - 21,872,572 (+)NCBICelera
RGSC_v3.1224,557,732 - 24,793,137 (+)NCBI
Cytogenetic Map2q12NCBI
AP3B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38578,000,522 - 78,294,698 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl577,991,640 - 78,294,762 (-)Ensemblhg38GRCh38
GRCh37577,296,346 - 77,590,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36577,333,906 - 77,626,284 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34577,333,906 - 77,626,284NCBI
Celera573,192,009 - 73,483,332 (-)NCBICelera
Cytogenetic Map5q14.1NCBI
HuRef572,504,871 - 72,797,261 (-)NCBIHuRef
CHM1_1576,732,015 - 77,024,021 (-)NCBICHM1_1
T2T-CHM13v2.0578,482,312 - 78,776,325 (-)NCBIT2T-CHM13v2.0
Ap3b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391394,492,332 - 94,702,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1394,495,468 - 94,702,825 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381394,358,960 - 94,566,316 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1394,358,960 - 94,566,317 (+)Ensemblmm10GRCm38
MGSCv371395,128,915 - 95,336,271 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361395,459,730 - 95,667,014 (+)NCBIMGSCv36mm8
Celera1397,976,815 - 98,179,412 (+)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1349.22NCBI
Ap3b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542522,792,616 - 23,051,737 (+)Ensembl
ChiLan1.0NW_00495542522,792,616 - 23,051,509 (+)NCBIChiLan1.0ChiLan1.0
AP3B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2437,008,432 - 37,299,817 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1535,163,000 - 35,453,444 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0537,015,518 - 37,305,769 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1537,502,986 - 37,835,904 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl537,503,162 - 37,840,205 (+)EnsemblpanPan2panpan1.1
AP3B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1328,481,974 - 28,748,095 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl328,481,038 - 28,751,258 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha329,722,995 - 29,988,777 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0328,405,848 - 28,672,345 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl328,405,824 - 28,675,022 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1328,341,769 - 28,607,713 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0328,320,012 - 28,585,750 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0328,647,884 - 28,914,348 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ap3b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213184,654,420 - 184,894,394 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365495,965,143 - 6,204,379 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365495,964,240 - 6,205,245 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AP3B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl286,873,290 - 87,142,768 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1286,875,922 - 87,142,722 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2288,534,908 - 88,719,584 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AP3B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1472,225,658 - 72,524,971 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl472,225,599 - 72,524,933 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604921,065,319 - 21,365,237 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ap3b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248692,459,947 - 2,741,328 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248692,459,370 - 2,741,529 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ap3b1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13201,782,994 - 201,982,976 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ap3b1
1576 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:328
Count of miRNA genes:187
Interacting mature miRNAs:211
Transcripts:ENSRNOT00000066302
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2142977529Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
9590080Insglur4Insulin/glucose ratio QTL 428.70.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)2615276751152767Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
731166Mamtr2Mammary tumor resistance QTL 20.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358154623581Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358144538110Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)2573632550736325Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat

Markers in Region
C78395  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2225,800,384 - 25,800,535 (+)MAPPERmRatBN7.2
Rnor_6.0224,224,962 - 24,225,112NCBIRnor6.0
Rnor_5.0243,394,542 - 43,394,692UniSTSRnor5.0
RGSC_v3.4224,872,218 - 24,872,368UniSTSRGSC3.4
Celera221,872,020 - 21,872,170UniSTS
Cytogenetic Map2q12UniSTS
RH141388  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2225,599,102 - 25,599,299 (+)MAPPERmRatBN7.2
Rnor_6.0224,023,868 - 24,024,064NCBIRnor6.0
Rnor_5.0243,194,268 - 43,194,464UniSTSRnor5.0
RGSC_v3.4224,669,112 - 24,669,308UniSTSRGSC3.4
Celera221,671,190 - 21,671,386UniSTS
Cytogenetic Map2q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000066302   ⟹   ENSRNOP00000060116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl227,335,003 - 27,535,682 (+)Ensembl
mRatBN7.2 Ensembl225,600,040 - 25,800,935 (+)Ensembl
Rnor_6.0 Ensembl224,024,834 - 24,225,514 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089599   ⟹   ENSRNOP00000069838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl224,024,791 - 24,226,224 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000164314   ⟹   ENSRNOP00000108327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl227,334,953 - 27,535,682 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172331   ⟹   ENSRNOP00000101627
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl227,334,900 - 27,537,702 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000173506   ⟹   ENSRNOP00000110034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl227,334,900 - 27,537,702 (+)Ensembl
RefSeq Acc Id: NM_001107646   ⟹   NP_001101116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8227,334,958 - 27,535,682 (+)NCBI
mRatBN7.2225,600,069 - 25,800,937 (+)NCBI
Rnor_6.0224,024,834 - 24,225,514 (+)NCBI
Rnor_5.0243,195,152 - 43,397,102 (+)NCBI
RGSC_v3.4224,670,078 - 24,872,770 (+)RGD
Celera221,672,156 - 21,872,572 (+)RGD
Sequence:
RefSeq Acc Id: XM_063281703   ⟹   XP_063137773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8227,331,241 - 27,535,683 (+)NCBI
RefSeq Acc Id: XM_063281704   ⟹   XP_063137774
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8227,331,241 - 27,505,973 (+)NCBI
RefSeq Acc Id: XM_063281705   ⟹   XP_063137775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8227,331,241 - 27,499,792 (+)NCBI
RefSeq Acc Id: XM_063281706   ⟹   XP_063137776
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8227,414,936 - 27,535,683 (+)NCBI
RefSeq Acc Id: XM_063281707   ⟹   XP_063137777
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8227,415,079 - 27,535,683 (+)NCBI
RefSeq Acc Id: XM_063281708   ⟹   XP_063137778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8227,415,079 - 27,535,683 (+)NCBI
RefSeq Acc Id: NP_001101116   ⟸   NM_001107646
- Sequence:
Ensembl Acc Id: ENSRNOP00000069838   ⟸   ENSRNOT00000089599
Ensembl Acc Id: ENSRNOP00000060116   ⟸   ENSRNOT00000066302
RefSeq Acc Id: XP_063137773   ⟸   XM_063281703
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063137774   ⟸   XM_063281704
- Peptide Label: isoform X2
- UniProtKB: D3ZIF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137775   ⟸   XM_063281705
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063137776   ⟸   XM_063281706
- Peptide Label: isoform X4
- UniProtKB: A6I4W8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137777   ⟸   XM_063281707
- Peptide Label: isoform X4
- UniProtKB: A6I4W8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137778   ⟸   XM_063281708
- Peptide Label: isoform X4
- UniProtKB: A6I4W8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101627   ⟸   ENSRNOT00000172331
Ensembl Acc Id: ENSRNOP00000110034   ⟸   ENSRNOT00000173506
Ensembl Acc Id: ENSRNOP00000108327   ⟸   ENSRNOT00000164314
Protein Domains
AP-3 complex subunit beta C-terminal   Beta-adaptin appendage C-terminal subdomain

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JWD6-F1-model_v2 AlphaFold A0A0G2JWD6 1-1096 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691081
Promoter ID:EPDNEW_R1597
Type:initiation region
Name:Ap3b1_1
Description:adaptor-related protein complex 3, beta 1 subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0224,024,789 - 24,024,849EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310256 AgrOrtholog
BioCyc Gene G2FUF-54830 BioCyc
Ensembl Genes ENSRNOG00000010624 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066302.3 UniProtKB/TrEMBL
  ENSRNOT00000164314.1 UniProtKB/TrEMBL
  ENSRNOT00000172331.1 UniProtKB/TrEMBL
  ENSRNOT00000173506 ENTREZGENE
  ENSRNOT00000173506.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro AP3_beta UniProtKB/TrEMBL
  AP3B1/2_C UniProtKB/TrEMBL
  AP3B1_Ser UniProtKB/TrEMBL
  AP3B_C UniProtKB/TrEMBL
  AP_beta UniProtKB/TrEMBL
  ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  B-adaptin_app_sub_C UniProtKB/TrEMBL
  Clathrin/coatomer_adapt-like_N UniProtKB/TrEMBL
KEGG Report rno:309969 UniProtKB/TrEMBL
NCBI Gene 309969 ENTREZGENE
PANTHER PTHR11134 UniProtKB/TrEMBL
Pfam Adaptin_N UniProtKB/TrEMBL
  AP3B1_C UniProtKB/TrEMBL
  AP3B1_C_2 UniProtKB/TrEMBL
  SEEEED UniProtKB/TrEMBL
PhenoGen Ap3b1 PhenoGen
PIRSF AP3_complex_beta UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010624 RatGTEx
SMART AP3B1_C UniProtKB/TrEMBL
  B2-adapt-app_C UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0ABK0LC99_RAT UniProtKB/TrEMBL
  A0ABK0LGV0_RAT UniProtKB/TrEMBL
  A0ABK0LIE5_RAT UniProtKB/TrEMBL
  A6I4W7 ENTREZGENE, UniProtKB/TrEMBL
  A6I4W8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIF5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-03 Ap3b1  adaptor related protein complex 3 subunit beta 1  Ap3b1  adaptor-related protein complex 3, beta 1 subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ap3b1  adaptor-related protein complex 3, beta 1 subunit   Ap3b1_predicted  adaptor-related protein complex 3, beta 1 subunit (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ap3b1_predicted  adaptor-related protein complex 3, beta 1 subunit (predicted)      Symbol and Name status set to approved 70820 APPROVED