Prkd3 (protein kinase D3) - Rat Genome Database

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Gene: Prkd3 (protein kinase D3) Rattus norvegicus
Analyze
Symbol: Prkd3
Name: protein kinase D3
RGD ID: 1310236
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in several cellular components, including Golgi apparatus; ciliary basal body; and nucleoplasm. Predicted to be active in cytosol. Orthologous to human PRKD3 (protein kinase D3); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313834; Prkcn; protein kinase C, nu; serine/threonine-protein kinase D3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8621,784,665 - 21,860,600 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl621,784,673 - 21,860,600 (+)EnsemblGRCr8
mRatBN7.2616,032,507 - 16,108,444 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,032,585 - 16,108,443 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx616,355,379 - 16,423,921 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0616,677,588 - 16,746,130 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,157,980 - 16,226,554 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.061,546,018 - 1,622,232 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl61,548,415 - 1,622,196 (-)Ensemblrn6Rnor6.0
Rnor_5.061,536,128 - 1,611,876 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.461,727,315 - 1,796,290 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera615,704,621 - 15,773,170 (+)NCBICelera
RGSC_v3.161,751,738 - 1,764,473 (-)NCBI
Cytogenetic Map6q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
decabromodiphenyl ether  (EXP)
deoxycholic acid  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
diclofenac  (ISO)
dicrotophos  (ISO)
diquat  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (EXP,ISO)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hexadecanoic acid  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
microcystin-LR  (ISO)
N-nitrosodiethylamine  (EXP)
oxaliplatin  (EXP)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
phlorizin  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rimonabant  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
Sunset Yellow FCF  (ISO)
tamoxifen  (ISO)
tartrazine  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IBA,IEA,ISO)
Golgi apparatus  (IEA)
membrane  (IEA)
plasma membrane  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Protein kinase D 3 is localized in vesicular structures and interacts with vesicle-associated membrane protein 2. Lu G, etal., Cell Signal. 2007 Apr;19(4):867-79. Epub 2006 Nov 16.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:21971046   PMID:22228765   PMID:27369082  


Genomics

Comparative Map Data
Prkd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8621,784,665 - 21,860,600 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl621,784,673 - 21,860,600 (+)EnsemblGRCr8
mRatBN7.2616,032,507 - 16,108,444 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,032,585 - 16,108,443 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx616,355,379 - 16,423,921 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0616,677,588 - 16,746,130 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,157,980 - 16,226,554 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.061,546,018 - 1,622,232 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl61,548,415 - 1,622,196 (-)Ensemblrn6Rnor6.0
Rnor_5.061,536,128 - 1,611,876 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.461,727,315 - 1,796,290 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera615,704,621 - 15,773,170 (+)NCBICelera
RGSC_v3.161,751,738 - 1,764,473 (-)NCBI
Cytogenetic Map6q12NCBI
PRKD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38237,250,502 - 37,324,833 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl237,250,502 - 37,324,833 (-)Ensemblhg38GRCh38
GRCh37237,477,645 - 37,551,976 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36237,331,149 - 37,397,726 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34237,389,298 - 37,455,873NCBI
Celera237,318,598 - 37,385,166 (-)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef237,217,514 - 37,283,993 (-)NCBIHuRef
CHM1_1237,407,074 - 37,473,671 (-)NCBICHM1_1
T2T-CHM13v2.0237,257,518 - 37,331,821 (-)NCBIT2T-CHM13v2.0
Prkd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391779,256,834 - 79,328,245 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1779,256,834 - 79,328,245 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381778,949,405 - 79,020,816 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,949,405 - 79,020,816 (-)Ensemblmm10GRCm38
MGSCv371779,348,745 - 79,420,156 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361778,855,607 - 78,918,364 (-)NCBIMGSCv36mm8
Celera1783,270,085 - 83,333,948 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1749.69NCBI
Prkd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554415,051,079 - 5,112,799 (-)Ensembl
ChiLan1.0NW_0049554415,051,079 - 5,112,791 (-)NCBIChiLan1.0ChiLan1.0
PRKD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21289,154,788 - 89,229,111 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A89,158,772 - 89,233,086 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A37,278,043 - 37,352,364 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A38,042,771 - 38,116,394 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A38,042,771 - 38,116,394 (-)EnsemblpanPan2panpan1.1
PRKD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11729,607,484 - 29,696,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1729,610,159 - 29,687,550 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1729,421,475 - 29,510,291 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01730,257,459 - 30,346,099 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1730,258,830 - 30,346,080 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11729,484,730 - 29,573,085 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01729,548,330 - 29,639,287 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01729,766,130 - 29,854,593 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Prkd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629242,313,646 - 42,382,136 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936663979,130 - 1,049,427 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936663979,136 - 1,047,633 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3102,842,229 - 102,941,329 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13102,840,666 - 102,949,128 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23109,438,196 - 109,546,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRKD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11470,064,678 - 70,142,790 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1470,072,330 - 70,140,176 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604541,805,140 - 41,881,579 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prkd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473818,853,963 - 18,927,122 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473818,851,165 - 18,927,177 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Prkd3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1714,215,751 - 14,282,932 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Prkd3
440 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:393
Count of miRNA genes:227
Interacting mature miRNAs:271
Transcripts:ENSRNOT00000007492
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
8693699Alc37Alcohol consumption QTL 372.60.224drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6125740059Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
8693690Alc35Alcohol consumption QTL 352.20.606drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat

Markers in Region
RH129843  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,108,080 - 16,108,260 (-)MAPPERmRatBN7.2
Rnor_6.061,546,202 - 1,546,381NCBIRnor6.0
Rnor_5.061,536,311 - 1,536,490UniSTSRnor5.0
RGSC_v3.461,727,498 - 1,727,677UniSTSRGSC3.4
Celera615,772,808 - 15,772,987UniSTS
Cytogenetic Map6q11UniSTS
RH131273  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,108,645 - 16,108,825 (-)MAPPERmRatBN7.2
Rnor_6.061,545,637 - 1,545,816NCBIRnor6.0
Rnor_5.061,535,746 - 1,535,925UniSTSRnor5.0
RGSC_v3.461,726,933 - 1,727,112UniSTSRGSC3.4
Celera615,773,373 - 15,773,552UniSTS
RH 3.4 Map632.8UniSTS
Cytogenetic Map6q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000007492   ⟹   ENSRNOP00000007491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl621,785,034 - 21,860,595 (+)Ensembl
mRatBN7.2 Ensembl616,039,896 - 16,108,443 (+)Ensembl
Rnor_6.0 Ensembl61,548,415 - 1,622,196 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084528   ⟹   ENSRNOP00000069846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl621,784,673 - 21,836,029 (+)Ensembl
mRatBN7.2 Ensembl616,071,139 - 16,083,871 (+)Ensembl
Rnor_6.0 Ensembl61,570,683 - 1,583,417 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095865   ⟹   ENSRNOP00000079860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl621,796,178 - 21,860,600 (+)Ensembl
mRatBN7.2 Ensembl616,044,022 - 16,108,443 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101507   ⟹   ENSRNOP00000077406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,032,585 - 16,041,481 (+)Ensembl
RefSeq Acc Id: NM_001024263   ⟹   NP_001019434
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,792,052 - 21,860,600 (+)NCBI
mRatBN7.2616,039,896 - 16,108,443 (+)NCBI
Rnor_6.061,546,019 - 1,614,851 (-)NCBI
Rnor_5.061,536,128 - 1,611,876 (-)NCBI
RGSC_v3.461,727,315 - 1,796,290 (-)RGD
Celera615,704,621 - 15,773,170 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239629   ⟹   XP_006239691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,981 - 21,860,596 (+)NCBI
mRatBN7.2616,032,819 - 16,108,436 (+)NCBI
Rnor_6.061,547,742 - 1,621,961 (-)NCBI
Rnor_5.061,536,128 - 1,611,876 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239631   ⟹   XP_006239693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,806,802 - 21,860,596 (+)NCBI
mRatBN7.2616,063,839 - 16,108,444 (+)NCBI
Rnor_6.061,547,742 - 1,591,441 (-)NCBI
Rnor_5.061,536,128 - 1,611,876 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112128   ⟹   XP_038968056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,696 - 21,860,596 (+)NCBI
mRatBN7.2616,032,552 - 16,108,444 (+)NCBI
RefSeq Acc Id: XM_039112129   ⟹   XP_038968057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,665 - 21,860,596 (+)NCBI
mRatBN7.2616,032,507 - 16,108,444 (+)NCBI
RefSeq Acc Id: XM_063261804   ⟹   XP_063117874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,988 - 21,860,596 (+)NCBI
RefSeq Acc Id: NP_001019434   ⟸   NM_001024263
- UniProtKB: D4A229 (UniProtKB/TrEMBL),   A0A8I6G5U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239691   ⟸   XM_006239629
- Peptide Label: isoform X1
- UniProtKB: D4A229 (UniProtKB/TrEMBL),   A0A8I6G5U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239693   ⟸   XM_006239631
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G5U2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069846   ⟸   ENSRNOT00000084528
Ensembl Acc Id: ENSRNOP00000007491   ⟸   ENSRNOT00000007492
RefSeq Acc Id: XP_038968057   ⟸   XM_039112129
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G5U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968056   ⟸   XM_039112128
- Peptide Label: isoform X1
- UniProtKB: D4A229 (UniProtKB/TrEMBL),   A0A8I6G5U2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077406   ⟸   ENSRNOT00000101507
Ensembl Acc Id: ENSRNOP00000079860   ⟸   ENSRNOT00000095865
RefSeq Acc Id: XP_063117874   ⟸   XM_063261804
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G5U2 (UniProtKB/TrEMBL),   D4A229 (UniProtKB/TrEMBL)
Protein Domains
PH   Phorbol-ester/DAG-type   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A229-F1-model_v2 AlphaFold D4A229 1-890 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694361
Promoter ID:EPDNEW_R4882
Type:initiation region
Name:Prkd3_2
Description:protein kinase D3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4883  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.061,583,411 - 1,583,471EPDNEW
RGD ID:13694358
Promoter ID:EPDNEW_R4883
Type:initiation region
Name:Prkd3_1
Description:protein kinase D3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4882  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.061,622,252 - 1,622,312EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310236 AgrOrtholog
BioCyc Gene G2FUF-38496 BioCyc
Ensembl Genes ENSRNOG00000005289 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007492 ENTREZGENE
  ENSRNOT00000007492.9 UniProtKB/TrEMBL
  ENSRNOT00000084528.3 UniProtKB/TrEMBL
  ENSRNOT00000095865 ENTREZGENE
  ENSRNOT00000095865.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  DAG/PE_bd UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Prot_Kinase_C-like_PE/DAG_bd UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Protein_Kinase_C_mu-related UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:313834 UniProtKB/TrEMBL
NCBI Gene 313834 ENTREZGENE
PANTHER PKC_mu_like UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE D3 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
  Ubiquitin_PRKD1_N UniProtKB/TrEMBL
PhenoGen Prkd3 PhenoGen
PIRSF PKC_mu_nu_D2 UniProtKB/TrEMBL
PRINTS DAGPEDOMAIN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005289 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A0G2JWE2_RAT UniProtKB/TrEMBL
  A0A8I6G5U2 ENTREZGENE, UniProtKB/TrEMBL
  D4A229 ENTREZGENE, UniProtKB/TrEMBL
  Q568X9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-17 Prkd3  protein kinase D3  Prkcn  protein kinase C, nu  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Prkcn  protein kinase C, nu  Prkcn_predicted  protein kinase C, nu (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Prkcn_predicted  protein kinase C, nu (predicted)      Symbol and Name status set to approved 70820 APPROVED