Tspy26 (testis specific protein, Y-linked 26) - Rat Genome Database

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Gene: Tspy26 (testis specific protein, Y-linked 26) Rattus norvegicus
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Symbol: Tspy26
Name: testis specific protein, Y-linked 26
RGD ID: 1310192
Description: Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to be located in chromatin. Predicted to be active in nucleus. Orthologous to human TSPY26P (testis specific protein Y-linked 26, pseudogene); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC296280; RGD1310192; similar to bA392M18.1 (novel protein similar to testis specific protein TSPY); TSPY-like 3; Tspyl3
RGD Orthologs
Human
Mouse
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83162,150,885 - 162,152,961 (-)NCBIGRCr8
mRatBN7.23141,690,653 - 141,692,729 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3141,689,899 - 141,692,670 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3145,595,329 - 145,597,405 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03154,179,126 - 154,181,202 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,918,254 - 151,920,330 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03148,704,896 - 148,706,972 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,704,900 - 148,706,972 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03155,390,626 - 155,392,702 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,574,208 - 143,576,284 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13143,480,798 - 143,481,826 (-)NCBI
Celera3140,436,883 - 140,438,959 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (IBA)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Tspy26
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83162,150,885 - 162,152,961 (-)NCBIGRCr8
mRatBN7.23141,690,653 - 141,692,729 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3141,689,899 - 141,692,670 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3145,595,329 - 145,597,405 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03154,179,126 - 154,181,202 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,918,254 - 151,920,330 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03148,704,896 - 148,706,972 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,704,900 - 148,706,972 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03155,390,626 - 155,392,702 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,574,208 - 143,576,284 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13143,480,798 - 143,481,826 (-)NCBI
Celera3140,436,883 - 140,438,959 (-)NCBICelera
Cytogenetic Map3q41NCBI
TSPY26P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382032,189,146 - 32,190,360 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2032,189,202 - 32,190,527 (-)EnsemblGRCh38hg38GRCh38
GRCh372030,776,949 - 30,778,163 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362030,240,610 - 30,241,824 (-)NCBINCBI36Build 36hg18NCBI36
Celera2027,533,301 - 27,534,515 (-)NCBICelera
Cytogenetic Map20q11.21NCBI
HuRef2027,565,460 - 27,566,674 (-)NCBIHuRef
CHM1_12030,680,795 - 30,682,009 (-)NCBICHM1_1
T2T-CHM13v2.02033,913,069 - 33,914,283 (-)NCBIT2T-CHM13v2.0
Tspyl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392153,064,290 - 153,067,361 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2153,064,290 - 153,067,361 (-)EnsemblGRCm39 Ensembl
GRCm382153,222,370 - 153,225,441 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2153,222,370 - 153,225,441 (-)EnsemblGRCm38mm10GRCm38
MGSCv372153,048,106 - 153,051,177 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362152,913,811 - 152,916,824 (-)NCBIMGSCv36mm8
Celera2159,049,947 - 159,053,019 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map275.41NCBI
LOC106506652
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11735,836,203 - 35,838,807 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21740,734,930 - 40,743,035 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Tspy26
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:378
Count of miRNA genes:215
Interacting mature miRNAs:262
Transcripts:ENSRNOT00000036956
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3140069424146976080Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 88 87 56 25 56 6 215 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000036956   ⟹   ENSRNOP00000037480
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3141,689,899 - 141,692,670 (-)Ensembl
Rnor_6.0 Ensembl3148,704,900 - 148,706,972 (-)Ensembl
RefSeq Acc Id: NM_001106527   ⟹   NP_001099997
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83162,150,885 - 162,152,961 (-)NCBI
mRatBN7.23141,690,653 - 141,692,729 (-)NCBI
Rnor_6.03148,704,896 - 148,706,972 (-)NCBI
Rnor_5.03155,390,626 - 155,392,702 (+)NCBI
RGSC_v3.43143,574,208 - 143,576,284 (-)RGD
Celera3140,436,883 - 140,438,959 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099997 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68711 (Get FASTA)   NCBI Sequence Viewer  
  EDL86012 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000037480.3
RefSeq Acc Id: NP_001099997   ⟸   NM_001106527
- UniProtKB: B5DEL0 (UniProtKB/TrEMBL),   A6KHU3 (UniProtKB/TrEMBL),   F7F760 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000037480   ⟸   ENSRNOT00000036956

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DEL0-F1-model_v2 AlphaFold B5DEL0 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310192 AgrOrtholog
BioCyc Gene G2FUF-47224 BioCyc
Ensembl Genes ENSRNOG00000026770 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036956.5 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1500 UniProtKB/TrEMBL
  Nucleosome assembly protein UniProtKB/TrEMBL
InterPro NAP-like_sf UniProtKB/TrEMBL
  NAP_family UniProtKB/TrEMBL
KEGG Report rno:296280 UniProtKB/TrEMBL
NCBI Gene 296280 ENTREZGENE
PANTHER NAP_family UniProtKB/TrEMBL
  TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 3-RELATED UniProtKB/TrEMBL
Pfam NAP UniProtKB/TrEMBL
PhenoGen Tspy26 PhenoGen
RatGTEx ENSRNOG00000026770 RatGTEx
Superfamily-SCOP SSF143113 UniProtKB/TrEMBL
UniProt A6KHU3 ENTREZGENE, UniProtKB/TrEMBL
  B5DEL0 ENTREZGENE
  F7F760 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B5DEL0 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-12-29 Tspy26  testis specific protein, Y-linked 26  Tspyl3  TSPY-like 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-27 Tspyl3  TSPY-like 3  RGD1310192_predicted  similar to bA392M18.1 (novel protein similar to testis specific protein TSPY) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1310192_predicted  similar to bA392M18.1 (novel protein similar to testis specific protein TSPY) (predicted)  LOC296280_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC296280_predicted  similar to bA392M18.1 (novel protein similar to testis specific protein TSPY) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL