Dapp1 (dual adaptor of phosphotyrosine and 3-phosphoinositides 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Dapp1 (dual adaptor of phosphotyrosine and 3-phosphoinositides 1) Rattus norvegicus
Analyze
Symbol: Dapp1
Name: dual adaptor of phosphotyrosine and 3-phosphoinositides 1
RGD ID: 1310189
Description: Predicted to enable phosphatidylinositol-3,4,5-trisphosphate binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be located in cytoplasm and membrane. Predicted to be active in plasma membrane. Orthologous to human DAPP1 (dual adaptor of phosphotyrosine and 3-phosphoinositides 1); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; B cell receptor signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; dual adaptor for phosphotyrosine and 3-phosphoinositides 1; dual adaptor of phosphotyrosine and 3-phosphoinositides; LOC362046
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,099,319 - 229,148,868 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2229,099,319 - 229,148,843 (-)EnsemblGRCr8
mRatBN7.22226,425,890 - 226,475,445 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,425,898 - 226,475,423 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2234,180,628 - 234,230,053 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,080,370 - 232,129,793 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02226,945,028 - 226,994,460 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,175,346 - 243,224,883 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,175,346 - 243,224,883 (-)Ensemblrn6Rnor6.0
Rnor_5.02261,723,376 - 261,772,469 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42235,423,487 - 235,474,068 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2218,592,238 - 218,641,599 (-)NCBICelera
RGSC_v3.12235,411,898 - 235,460,789 (-)NCBI
Cytogenetic Map2q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)
osteoarthritis  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11001876   PMID:17823121  


Genomics

Comparative Map Data
Dapp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,099,319 - 229,148,868 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2229,099,319 - 229,148,843 (-)EnsemblGRCr8
mRatBN7.22226,425,890 - 226,475,445 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,425,898 - 226,475,423 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2234,180,628 - 234,230,053 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,080,370 - 232,129,793 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02226,945,028 - 226,994,460 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,175,346 - 243,224,883 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,175,346 - 243,224,883 (-)Ensemblrn6Rnor6.0
Rnor_5.02261,723,376 - 261,772,469 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42235,423,487 - 235,474,068 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2218,592,238 - 218,641,599 (-)NCBICelera
RGSC_v3.12235,411,898 - 235,460,789 (-)NCBI
Cytogenetic Map2q43NCBI
DAPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38499,816,827 - 99,872,333 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl499,816,816 - 99,870,190 (+)Ensemblhg38GRCh38
GRCh374100,737,984 - 100,791,347 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364100,957,013 - 101,010,334 (+)NCBIBuild 36Build 36hg18NCBI36
Build 344101,095,167 - 101,148,489NCBI
Celera498,035,400 - 98,088,767 (+)NCBICelera
Cytogenetic Map4q23NCBI
HuRef496,476,303 - 96,529,671 (+)NCBIHuRef
CHM1_14100,714,487 - 100,767,854 (+)NCBICHM1_1
T2T-CHM13v2.04103,132,302 - 103,187,798 (+)NCBIT2T-CHM13v2.0
Dapp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393137,636,768 - 137,687,331 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3137,636,768 - 137,687,306 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm383137,931,007 - 137,981,549 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3137,931,007 - 137,981,545 (-)Ensemblmm10GRCm38
MGSCv373137,593,970 - 137,644,513 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363137,868,992 - 137,918,911 (-)NCBIMGSCv36mm8
Celera3144,341,736 - 144,392,586 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map363.98NCBI
Dapp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554967,813,540 - 7,855,539 (-)Ensembl
ChiLan1.0NW_0049554967,813,540 - 7,855,754 (-)NCBIChiLan1.0ChiLan1.0
DAPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,898,439 - 97,953,780 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1498,182,243 - 98,237,589 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0492,240,003 - 92,292,624 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,901,213 - 102,956,357 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,901,220 - 102,954,210 (+)EnsemblpanPan2panpan1.1
DAPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13221,765,401 - 21,812,532 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3221,766,526 - 21,812,608 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3220,083,207 - 20,131,390 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03221,986,478 - 22,034,664 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3221,987,581 - 22,037,991 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13221,962,957 - 22,011,140 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03221,750,131 - 21,798,306 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03218,069,897 - 18,118,126 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dapp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530119,794,761 - 19,845,073 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365203,138,218 - 3,188,508 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365203,138,213 - 3,188,498 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8120,634,738 - 120,701,340 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.18120,645,100 - 120,701,453 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28129,824,346 - 129,850,822 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DAPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1747,947,931 - 48,001,659 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl747,948,160 - 48,001,649 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603726,419,964 - 26,473,641 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dapp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248307,316,487 - 7,352,130 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248307,318,175 - 7,352,234 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dapp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1321,191,472 - 21,238,818 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dapp1
442 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:938
Count of miRNA genes:338
Interacting mature miRNAs:445
Transcripts:ENSRNOT00000014139
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631563Hcuc3Hepatic copper content QTL 33.87liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2212145502231732847Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2184482291229482291Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2210956252251712708Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2202029709236904960Rat
8693697Alc36Alcohol consumption QTL 3620.592drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2219814164239320906Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2214404877251712708Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2204795005249795005Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2214404877251712708Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2218051934251712708Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2186850607231850607Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2192287802237287802Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2214404877251712708Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2214404877251712708Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2196140964251540988Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2205135267250135267Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2221088977243501206Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2192287802229609668Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2188565047233565047Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2184856304229856304Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2184856304229856304Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2203664411248664411Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2184856304229856304Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2214404877251712708Rat
8693622Alc26Alcohol consumption QTL 262.40.667drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2223810546243965570Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2192287802237287802Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2184856304229856304Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat

Markers in Region
RH127587  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22226,426,058 - 226,426,239 (+)MAPPERmRatBN7.2
Rnor_6.02243,175,507 - 243,175,687NCBIRnor6.0
Rnor_5.02261,723,572 - 261,723,752UniSTSRnor5.0
RGSC_v3.42235,423,648 - 235,423,828UniSTSRGSC3.4
Celera2218,592,399 - 218,592,579UniSTS
RH 3.4 Map21606.0UniSTS
Cytogenetic Map2q44UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
20 13 84 214 91 90 59 158 59 6 479 285 22 188 107 124 31 31 31

Sequence


Ensembl Acc Id: ENSRNOT00000014139   ⟹   ENSRNOP00000014139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2229,099,319 - 229,148,843 (-)Ensembl
mRatBN7.2 Ensembl2226,425,898 - 226,475,423 (-)Ensembl
Rnor_6.0 Ensembl2243,175,346 - 243,224,883 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115021   ⟹   ENSRNOP00000088868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2229,099,319 - 229,148,738 (-)Ensembl
mRatBN7.2 Ensembl2226,425,898 - 226,475,318 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116150   ⟹   ENSRNOP00000094432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2229,103,904 - 229,148,843 (-)Ensembl
mRatBN7.2 Ensembl2226,425,898 - 226,475,423 (-)Ensembl
RefSeq Acc Id: NM_001108568   ⟹   NP_001102038
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,099,319 - 229,148,843 (-)NCBI
mRatBN7.22226,425,898 - 226,475,423 (-)NCBI
Rnor_6.02243,175,346 - 243,224,883 (-)NCBI
Rnor_5.02261,723,376 - 261,772,469 (-)NCBI
RGSC_v3.42235,423,487 - 235,474,068 (-)RGD
Celera2218,592,238 - 218,641,599 (-)RGD
Sequence:
RefSeq Acc Id: XM_039102724   ⟹   XP_038958652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,099,323 - 229,148,868 (-)NCBI
mRatBN7.22226,425,890 - 226,475,445 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001102038 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958652 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL82303 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014139
  ENSRNOP00000014139.5
  ENSRNOP00000088868.1
  ENSRNOP00000094432.2
RefSeq Acc Id: NP_001102038   ⟸   NM_001108568
- UniProtKB: D4ACC1 (UniProtKB/TrEMBL),   A6HW17 (UniProtKB/TrEMBL),   A0A8I6AM49 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014139   ⟸   ENSRNOT00000014139
RefSeq Acc Id: XP_038958652   ⟸   XM_039102724
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AM49 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000094432   ⟸   ENSRNOT00000116150
Ensembl Acc Id: ENSRNOP00000088868   ⟸   ENSRNOT00000115021
Protein Domains
PH   SH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ACC1-F1-model_v2 AlphaFold D4ACC1 1-279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691780
Promoter ID:EPDNEW_R2305
Type:initiation region
Name:Dapp1_1
Description:dual adaptor of phosphotyrosine and 3-phosphoinositides 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02243,224,918 - 243,224,978EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310189 AgrOrtholog
BioCyc Gene G2FUF-51103 BioCyc
Ensembl Genes ENSRNOG00000010575 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014139 ENTREZGENE
  ENSRNOT00000014139.7 UniProtKB/TrEMBL
  ENSRNOT00000115021.2 UniProtKB/TrEMBL
  ENSRNOT00000116150.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
InterPro DAPP1_SH2 UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  PI-Interact_SigTrans_Reg UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
KEGG Report rno:362046 UniProtKB/TrEMBL
NCBI Gene 362046 ENTREZGENE
PANTHER DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE UniProtKB/TrEMBL
  TANDEM PH DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PhenoGen Dapp1 PhenoGen
PRINTS PI3KINASEP85 UniProtKB/TrEMBL
  SH2DOMAIN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010575 RatGTEx
SMART SH2 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A8I6AM49 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GHI5_RAT UniProtKB/TrEMBL
  A6HW17 ENTREZGENE, UniProtKB/TrEMBL
  D4ACC1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-01 Dapp1  dual adaptor of phosphotyrosine and 3-phosphoinositides 1  Dapp1  dual adaptor of phosphotyrosine and 3-phosphoinositides  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Dapp1  dual adaptor of phosphotyrosine and 3-phosphoinositides  Dapp1  dual adaptor for phosphotyrosine and 3-phosphoinositides 1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dapp1  dual adaptor for phosphotyrosine and 3-phosphoinositides 1   Dapp1_predicted  dual adaptor for phosphotyrosine and 3-phosphoinositides 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dapp1_predicted  dual adaptor for phosphotyrosine and 3-phosphoinositides 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED