Lacc1 (laccase domain containing 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Lacc1 (laccase domain containing 1) Rattus norvegicus
Analyze
Symbol: Lacc1
Name: laccase domain containing 1
RGD ID: 1310185
Description: Predicted to enable adenosine deaminase activity; copper ion binding activity; and pentosyltransferase activity. Predicted to be involved in several processes, including positive regulation of cytokine production involved in immune response; regulation of cellular pH; and regulation of defense response. Predicted to be located in endoplasmic reticulum; nucleus; and peroxisome. Human ortholog(s) of this gene implicated in systemic juvenile rheumatoid arthritis. Orthologous to human LACC1 (laccase domain containing 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC100359875; laccase (multicopper oxidoreductase) domain containing 1; laccase domain-containing protein 1; LOC100359875; LOC313790; purine nucleoside phosphorylase LACC1; RGD1310185; similar to RIKEN cDNA 9030625A04
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81558,799,477 - 58,816,840 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1558,786,637 - 58,816,840 (-)EnsemblGRCr8
mRatBN7.21552,390,267 - 52,407,630 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1552,395,183 - 52,407,545 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1556,533,501 - 56,545,915 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01557,651,820 - 57,664,234 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01554,471,165 - 54,483,607 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1558,081,500 - 58,093,947 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1557,128,217 - 57,140,664 (-)NCBILyon_Normotensive
Lyon_Hypertensive1557,963,673 - 57,976,120 (-)NCBILyon_Hypertensive
F344_StmMcwi1555,950,647 - 55,963,094 (-)NCBIF344_StmMcwi
Rnor_6.01559,199,537 - 59,217,200 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1559,209,829 - 59,215,803 (-)Ensemblrn6Rnor6.0
Rnor_5.01562,881,963 - 62,899,616 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41558,485,517 - 58,497,172 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1552,000,952 - 52,018,611 (-)NCBICelera
RGSC_v3.11558,501,274 - 58,511,923 (-)NCBI
Cytogenetic Map15q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
D-glucose  (ISO)
dexamethasone  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
fenthion  (ISO)
glucose  (ISO)
glycidol  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
mercury dibromide  (ISO)
methidathion  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
Nutlin-3  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (EXP)
thioacetamide  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:27478939   PMID:36610229   PMID:38064597  


Genomics

Comparative Map Data
Lacc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81558,799,477 - 58,816,840 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1558,786,637 - 58,816,840 (-)EnsemblGRCr8
mRatBN7.21552,390,267 - 52,407,630 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1552,395,183 - 52,407,545 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1556,533,501 - 56,545,915 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01557,651,820 - 57,664,234 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01554,471,165 - 54,483,607 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1558,081,500 - 58,093,947 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1557,128,217 - 57,140,664 (-)NCBILyon_Normotensive
Lyon_Hypertensive1557,963,673 - 57,976,120 (-)NCBILyon_Hypertensive
F344_StmMcwi1555,950,647 - 55,963,094 (-)NCBIF344_StmMcwi
Rnor_6.01559,199,537 - 59,217,200 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1559,209,829 - 59,215,803 (-)Ensemblrn6Rnor6.0
Rnor_5.01562,881,963 - 62,899,616 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41558,485,517 - 58,497,172 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1552,000,952 - 52,018,611 (-)NCBICelera
RGSC_v3.11558,501,274 - 58,511,923 (-)NCBI
Cytogenetic Map15q11NCBI
LACC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381343,879,178 - 43,893,932 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1343,878,917 - 43,895,091 (+)Ensemblhg38GRCh38
GRCh371344,453,314 - 44,468,068 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361343,351,969 - 43,364,438 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1325,509,562 - 25,524,213 (+)NCBICelera
Cytogenetic Map13q14.11NCBI
HuRef1325,255,193 - 25,269,831 (+)NCBIHuRef
CHM1_11344,420,991 - 44,435,621 (+)NCBICHM1_1
T2T-CHM13v2.01343,098,039 - 43,112,848 (+)NCBIT2T-CHM13v2.0
Lacc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391477,261,640 - 77,274,344 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1477,261,640 - 77,274,344 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381477,021,739 - 77,036,929 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1477,024,200 - 77,036,904 (-)Ensemblmm10GRCm38
MGSCv371477,424,008 - 77,436,424 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361475,758,356 - 75,770,772 (-)NCBIMGSCv36mm8
Celera1474,530,246 - 74,545,309 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1440.63NCBI
Lacc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555181,793,352 - 1,805,808 (+)Ensembl
ChiLan1.0NW_0049555181,794,067 - 1,809,150 (+)NCBIChiLan1.0ChiLan1.0
LACC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21443,383,784 - 43,398,826 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11334,467,830 - 34,482,682 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01325,047,306 - 25,063,644 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13198,998,153 - 199,012,974 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3198,998,153 - 199,012,230 (-)EnsemblpanPan2panpan1.1
LACC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1226,824,942 - 7,002,888 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha226,814,398 - 6,995,732 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0227,026,620 - 7,208,242 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl227,181,500 - 7,286,084 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1226,725,413 - 6,907,334 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0226,787,280 - 6,969,201 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0226,794,442 - 6,976,100 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LACC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1123,141,425 - 23,159,547 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11123,143,708 - 23,159,790 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21123,597,036 - 23,612,028 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LACC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1321,995,405 - 22,008,310 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl321,997,133 - 22,006,418 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605722,006,186 - 22,158,633 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lacc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474811,187,316 - 11,194,841 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474811,150,678 - 11,194,794 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lacc1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11247,358,901 - 47,366,026 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lacc1
105 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:64
Interacting mature miRNAs:65
Transcripts:ENSRNOT00000032295, ENSRNOT00000032301
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155720389580107161Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat

Markers in Region
BE096152  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81558,815,541 - 58,815,711 (+)Marker Load Pipeline
mRatBN7.21552,406,331 - 52,406,500 (+)MAPPERmRatBN7.2
Rnor_6.01559,215,607 - 59,215,775NCBIRnor6.0
Rnor_5.01562,898,033 - 62,898,201UniSTSRnor5.0
RGSC_v3.41558,495,986 - 58,496,154UniSTSRGSC3.4
Celera1552,017,018 - 52,017,186UniSTS
RH 3.4 Map15494.11UniSTS
Cytogenetic Map15q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 355 192 11 144 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000032301   ⟹   ENSRNOP00000036081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1558,804,083 - 58,816,840 (-)Ensembl
mRatBN7.2 Ensembl1552,395,183 - 52,407,545 (-)Ensembl
Rnor_6.0 Ensembl1559,209,829 - 59,215,803 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000159322   ⟹   ENSRNOP00000108496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1558,786,637 - 58,816,840 (-)Ensembl
RefSeq Acc Id: NM_001399500   ⟹   NP_001386429
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81558,804,393 - 58,816,840 (-)NCBI
mRatBN7.21552,395,183 - 52,407,630 (-)NCBI
Dahl_SR_JrHsd1558,081,500 - 58,093,947 (-)NCBI
Lyon_Normotensive1557,128,217 - 57,140,664 (-)NCBI
Lyon_Hypertensive1557,963,673 - 57,976,120 (-)NCBI
F344_StmMcwi1555,950,647 - 55,963,094 (-)NCBI
RefSeq Acc Id: XM_039094027   ⟹   XP_038949955
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81558,799,477 - 58,816,597 (-)NCBI
mRatBN7.21552,390,267 - 52,407,182 (-)NCBI
RefSeq Acc Id: XM_039094029   ⟹   XP_038949957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81558,799,477 - 58,816,833 (-)NCBI
mRatBN7.21552,390,267 - 52,407,618 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001386429 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949955 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949957 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM02325 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000036081
  ENSRNOP00000036081.4
  ENSRNOP00000108496.1
Ensembl Acc Id: ENSRNOP00000036081   ⟸   ENSRNOT00000032301
RefSeq Acc Id: XP_038949957   ⟸   XM_039094029
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949955   ⟸   XM_039094027
- Peptide Label: isoform X1
- UniProtKB: D3ZCD2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386429   ⟸   NM_001399500
- UniProtKB: D3ZCD2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108496   ⟸   ENSRNOT00000159322

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZCD2-F1-model_v2 AlphaFold D3ZCD2 1-430 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310185 AgrOrtholog
BioCyc Gene G2FUF-13035 BioCyc
BioCyc Pathway P121-PWY [adenine and adenosine salvage I] BioCyc
  PWY-4202 [arsenic detoxification (mammals)] BioCyc
  PWY-5695 [inosine 5'-phosphate degradation] BioCyc
  PWY-6608 [guanosine nucleotides degradation III] BioCyc
  PWY-6609 [adenine and adenosine salvage III] BioCyc
  PWY-6620 [guanine and guanosine salvage I] BioCyc
  PWY-7179 [purine deoxyribonucleosides degradation I] BioCyc
  PWY-7179-1 [purine deoxyribonucleosides degradation II] BioCyc
  PWY0-1296 [purine ribonucleosides degradation] BioCyc
  SALVADEHYPOX-PWY [adenosine nucleotides degradation II] BioCyc
  SALVPURINE2-PWY [xanthine and xanthosine salvage] BioCyc
BioCyc Pathway Image P121-PWY BioCyc
  PWY-4202 BioCyc
  PWY-5695 BioCyc
  PWY-6608 BioCyc
  PWY-6609 BioCyc
  PWY-6620 BioCyc
  PWY-7179 BioCyc
  PWY-7179-1 BioCyc
  PWY0-1296 BioCyc
  SALVADEHYPOX-PWY BioCyc
  SALVPURINE2-PWY BioCyc
Ensembl Genes ENSRNOG00000022094 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032301 ENTREZGENE
  ENSRNOT00000032301.8 UniProtKB/TrEMBL
  ENSRNOT00000159322.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.140.10 UniProtKB/TrEMBL
InterPro Cu_polyphenol_OxRdtase_Laccase UniProtKB/TrEMBL
  Cu_polyphenol_OxRdtase_sf UniProtKB/TrEMBL
  Cytotoxic_necrot_fac-like_cat UniProtKB/TrEMBL
NCBI Gene 313790 ENTREZGENE
PANTHER PTHR30616 UniProtKB/TrEMBL
  PURINE NUCLEOSIDE PHOSPHORYLASE LACC1 UniProtKB/TrEMBL
Pfam Cu-oxidase_4 UniProtKB/TrEMBL
PhenoGen Lacc1 PhenoGen
RatGTEx ENSRNOG00000022094 RatGTEx
Superfamily-SCOP Cytotoxic_necrot_fac-like_cat UniProtKB/TrEMBL
UniProt A0ABK0LVZ9_RAT UniProtKB/TrEMBL
  D3ZCD2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Lacc1  laccase domain containing 1  Lacc1  laccase (multicopper oxidoreductase) domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 Lacc1  laccase (multicopper oxidoreductase) domain containing 1  LOC100359875  hypothetical protein LOC100359875  Data merged from RGD:2323268 737654 PROVISIONAL
2011-09-02 Lacc1  laccase (multicopper oxidoreductase) domain containing 1  RGD1310185  similar to RIKEN cDNA 9030625A04  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100359875  hypothetical protein LOC100359875      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1310185  similar to RIKEN cDNA 9030625A04   RGD1310185_predicted  similar to RIKEN cDNA 9030625A04 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1310185_predicted  similar to RIKEN cDNA 9030625A04 (predicted)  LOC313790_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313790_predicted  similar to RIKEN cDNA 9030625A04 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL