Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EEA1 mRNA | CTD | PMID:22079256 | (1->4)-beta-D-glucan | multiple interactions | ISO | Eea1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EEA1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Eea1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of EEA1 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EEA1 mRNA | CTD | PMID:33387578 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,4,6-tribromophenol | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of EEA1 mRNA | CTD | PMID:21346803 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | tetrabromobisphenol A results in increased expression of EEA1 mRNA | CTD | PMID:25172293 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Eea1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of EEA1 mRNA | CTD | PMID:26251327 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of EEA1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of EEA1 mRNA | CTD | PMID:19770486 | aristolochic acid A | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of EEA1 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | EEA1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of EEA1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | EEA1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of EEA1 gene | CTD | PMID:25304211 | arsenite(3-) | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to EEA1 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of EEA1 mRNA | CTD | PMID:21932408 and PMID:26063408 | bisphenol A | decreases expression | ISO | Eea1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of EEA1 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of EEA1 protein | CTD | PMID:37567409 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of EEA1 gene | CTD | PMID:28505145 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of EEA1 mRNA | CTD | PMID:25181051 | Bisphenol B | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of EEA1 protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of EEA1 mRNA | CTD | PMID:35387338 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of EEA1 mRNA | CTD | PMID:32479839 | cadmium dichloride | decreases expression | ISO | Eea1 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of EEA1 mRNA | CTD | PMID:24982889 | cadmium dichloride | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of EEA1 mRNA | CTD | PMID:26472689 | cadmium sulfate | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of EEA1 mRNA | CTD | PMID:18654764 | caffeine | decreases phosphorylation | ISO | EEA1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of EEA1 protein | CTD | PMID:35688186 | chloroquine | affects localization | ISO | EEA1 (Homo sapiens) | 6480464 | Chloroquine affects the localization of EEA1 protein | CTD | PMID:29940786 | cisplatin | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of EEA1 mRNA | CTD | PMID:27392435 | clobetasol | decreases expression | ISO | Eea1 (Mus musculus) | 6480464 | Clobetasol results in decreased expression of EEA1 mRNA | CTD | PMID:27462272 | cobalt dichloride | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of EEA1 mRNA | CTD | PMID:18654764 | crocidolite asbestos | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in increased expression of EEA1 mRNA | CTD | PMID:18687144 | deguelin | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | deguelin results in increased expression of EEA1 mRNA | CTD | PMID:33512557 | dibutyl phthalate | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of EEA1 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EEA1 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of EEA1 mRNA | CTD | PMID:29803840 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of EEA1 protein | CTD | PMID:20133374 | ethyl methanesulfonate | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of EEA1 mRNA | CTD | PMID:23649840 | fluoranthene | multiple interactions | ISO | Eea1 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of EEA1 mRNA | CTD | PMID:28329830 | FR900359 | affects phosphorylation | ISO | EEA1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of EEA1 protein | CTD | PMID:37730182 | geldanamycin | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of EEA1 mRNA | CTD | PMID:26705709 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of EEA1 mRNA | CTD | PMID:33387578 | gold atom | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Gold results in decreased expression of EEA1 mRNA | CTD | PMID:25523186 | gold(0) | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Gold results in decreased expression of EEA1 mRNA | CTD | PMID:25523186 | ivermectin | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of EEA1 protein | CTD | PMID:32959892 | lead diacetate | decreases methylation | EXP | | 6480464 | lead acetate results in decreased methylation of EEA1 gene | CTD | PMID:29571894 | lead(II) chloride | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of EEA1 mRNA | CTD | PMID:18654764 | mercury atom | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Mercury results in increased expression of EEA1 mRNA | CTD | PMID:16823088 | mercury(0) | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Mercury results in increased expression of EEA1 mRNA | CTD | PMID:16823088 | methidathion | decreases expression | ISO | Eea1 (Mus musculus) | 6480464 | methidathion results in decreased expression of EEA1 mRNA | CTD | PMID:34813904 | methyl methanesulfonate | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of EEA1 mRNA | CTD | PMID:23649840 | miconazole | decreases expression | ISO | Eea1 (Mus musculus) | 6480464 | Miconazole results in decreased expression of EEA1 mRNA | CTD | PMID:27462272 | nickel atom | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of EEA1 mRNA | CTD | PMID:23195993 | ozone | multiple interactions | ISO | Eea1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of EEA1 mRNA | CTD | PMID:27106289 | paracetamol | affects expression | ISO | Eea1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of EEA1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of EEA1 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of EEA1 mRNA | CTD | PMID:21420995 | paracetamol | multiple interactions | ISO | Eea1 (Mus musculus) | 6480464 | MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of EEA1 mRNA] | CTD | PMID:18700144 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of EEA1 mRNA | CTD | PMID:32680482 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of EEA1 mRNA | CTD | PMID:27153767 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Eea1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EEA1 mRNA | CTD | PMID:36331819 | phenobarbital | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of EEA1 mRNA | CTD | PMID:19270015 | phorbol 13-acetate 12-myristate | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | Tetradecanoylphorbol Acetate results in increased localization of [SLC6A3 protein co-treated with EEA1 protein] | CTD | PMID:22683840 | poly(I:C) | multiple interactions | EXP | | 6480464 | [Poly I-C co-treated with HU 211] results in decreased expression of EEA1 mRNA | CTD | PMID:26923065 | potassium chromate | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EEA1 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of EEA1 mRNA | CTD | PMID:22079256 | potassium dichromate | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of EEA1 mRNA | CTD | PMID:23608068 | resveratrol | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of EEA1 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EEA1 mRNA | CTD | PMID:27188386 | sodium arsenate | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of EEA1 mRNA | CTD | PMID:21795629 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of EEA1 protein | CTD | PMID:29459688 | sunitinib | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of EEA1 mRNA | CTD | PMID:31533062 | testosterone | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of EEA1 mRNA | CTD | PMID:33359661 | tetrachloromethane | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of EEA1 mRNA | CTD | PMID:31919559 | thifluzamide | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | thifluzamide results in increased expression of EEA1 mRNA | CTD | PMID:33512557 | thimerosal | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of EEA1 mRNA | CTD | PMID:27188386 | titanium dioxide | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of EEA1 mRNA | CTD | PMID:29264374 | trichloroethene | decreases methylation | EXP | | 6480464 | Trichloroethylene results in decreased methylation of EEA1 gene | CTD | PMID:27618143 | trichostatin A | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of EEA1 mRNA | CTD | PMID:24935251 | trimellitic anhydride | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of EEA1 mRNA | CTD | PMID:19042947 | triptonide | increases expression | ISO | Eea1 (Mus musculus) | 6480464 | triptonide results in increased expression of EEA1 mRNA | CTD | PMID:33045310 | valproic acid | increases expression | ISO | EEA1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of EEA1 mRNA | CTD | PMID:26272509 more ... | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of EEA1 mRNA | CTD | PMID:29427782 | valproic acid | multiple interactions | ISO | EEA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EEA1 mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | ISO | EEA1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of EEA1 mRNA | CTD | PMID:27188386 | |