Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ptrh1 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PTRH1 mRNA] | CTD | PMID:31150632 | Ptrh1 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | PTRH1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PTRH1 mRNA | CTD | PMID:22079256 | Ptrh1 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Ptrh1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PTRH1 mRNA | CTD | PMID:36331819 | Ptrh1 | Rat | 1,2-dichloroethane | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of PTRH1 mRNA | CTD | PMID:28189721|PMID:28960355 | Ptrh1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Ptrh1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PTRH1 mRNA | CTD | PMID:22206623 | Ptrh1 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of PTRH1 mRNA | CTD | PMID:25380136 | Ptrh1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ptrh1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of PTRH1 mRNA | CTD | PMID:19465110 | Ptrh1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PTRH1 mRNA | CTD | PMID:33387578 | Ptrh1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ptrh1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTRH1 mRNA | CTD | PMID:21570461 | Ptrh1 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of PTRH1 mRNA | CTD | PMID:21346803 | Ptrh1 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PTRH1 mRNA | CTD | PMID:30851411 | Ptrh1 | Rat | benzo[a]pyrene | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PTRH1 mRNA | CTD | PMID:22228805 | Ptrh1 | Rat | Benzo[k]fluoranthene | decreases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of PTRH1 mRNA | CTD | PMID:26377693 | Ptrh1 | Rat | bisphenol A | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PTRH1 mRNA | CTD | PMID:32156529 | Ptrh1 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of PTRH1 mRNA | CTD | PMID:33453195 | Ptrh1 | Rat | cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of PTRH1 mRNA | CTD | PMID:22110744 | Ptrh1 | Rat | carbon nanotube | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of PTRH1 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681 | Ptrh1 | Rat | cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of PTRH1 mRNA | CTD | PMID:18500788 | Ptrh1 | Rat | choline | multiple interactions | ISO | Ptrh1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Ptrh1 | Rat | cyclosporin A | increases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PTRH1 mRNA | CTD | PMID:20106945|PMID:27989131 | Ptrh1 | Rat | decabromodiphenyl ether | affects expression | ISO | PTRH1 (Homo sapiens) | 6480464 | decabromobiphenyl ether affects the expression of PTRH1 mRNA | CTD | PMID:24834073 | Ptrh1 | Rat | dioxygen | multiple interactions | ISO | Ptrh1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PTRH1 mRNA | CTD | PMID:30529165 | Ptrh1 | Rat | dopamine | increases expression | EXP | | 6480464 | Dopamine results in increased expression of PTRH1 mRNA | CTD | PMID:21983523 | Ptrh1 | Rat | dorsomorphin | multiple interactions | ISO | PTRH1 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Ptrh1 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of PTRH1 mRNA | CTD | PMID:29391264 | Ptrh1 | Rat | ethyl methanesulfonate | increases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of PTRH1 mRNA | CTD | PMID:23649840 | Ptrh1 | Rat | fenoldopam | increases expression | EXP | | 6480464 | Fenoldopam results in increased expression of PTRH1 mRNA | CTD | PMID:21983523 | Ptrh1 | Rat | folic acid | multiple interactions | ISO | Ptrh1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PTRH1 mRNA; [Methionine deficiency co-treated more ... | CTD | PMID:20938992|PMID:22206623 | Ptrh1 | Rat | folic acid | decreases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PTRH1 mRNA | CTD | PMID:25629700 | Ptrh1 | Rat | gallic acid | increases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Gallic Acid results in increased expression of PTRH1 mRNA | CTD | PMID:34408198 | Ptrh1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PTRH1 mRNA | CTD | PMID:33387578 | Ptrh1 | Rat | ivermectin | decreases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PTRH1 protein | CTD | PMID:32959892 | Ptrh1 | Rat | L-methionine | multiple interactions | ISO | Ptrh1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Ptrh1 | Rat | menadione | affects expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of PTRH1 mRNA | CTD | PMID:20044591 | Ptrh1 | Rat | methyl methanesulfonate | increases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of PTRH1 mRNA | CTD | PMID:23649840 | Ptrh1 | Rat | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of PTRH1 mRNA | CTD | PMID:25380136 | Ptrh1 | Rat | okadaic acid | increases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of PTRH1 mRNA | CTD | PMID:38832940 | Ptrh1 | Rat | ozone | multiple interactions | ISO | Ptrh1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Ptrh1 | Rat | p-chloromercuribenzoic acid | decreases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of PTRH1 mRNA | CTD | PMID:26272509 | Ptrh1 | Rat | p-chloromercuribenzoic acid | multiple interactions | ISO | PTRH1 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Ptrh1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PTRH1 mRNA | CTD | PMID:33387578 | Ptrh1 | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of PTRH1 mRNA | CTD | PMID:32680482 | Ptrh1 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of PTRH1 mRNA | CTD | PMID:37995155 | Ptrh1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ptrh1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PTRH1 mRNA | CTD | PMID:36331819 | Ptrh1 | Rat | potassium chromate | decreases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of PTRH1 mRNA | CTD | PMID:22079256 | Ptrh1 | Rat | potassium chromate | multiple interactions | ISO | PTRH1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PTRH1 mRNA | CTD | PMID:22079256 | Ptrh1 | Rat | rac-lactic acid | decreases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PTRH1 mRNA | CTD | PMID:30851411 | Ptrh1 | Rat | rotenone | decreases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of PTRH1 protein | CTD | PMID:39603559 | Ptrh1 | Rat | SB 431542 | multiple interactions | ISO | PTRH1 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Ptrh1 | Rat | silicon dioxide | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of PTRH1 mRNA | CTD | PMID:29203145 | Ptrh1 | Rat | sodium arsenate | decreases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of PTRH1 mRNA | CTD | PMID:39847705 | Ptrh1 | Rat | sodium arsenite | decreases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PTRH1 mRNA | CTD | PMID:34032870 | Ptrh1 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of PTRH1 mRNA | CTD | PMID:19281266 | Ptrh1 | Rat | tetrachloromethane | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of PTRH1 mRNA | CTD | PMID:27339419|PMID:31919559 | Ptrh1 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of PTRH1 mRNA | CTD | PMID:31150632 | Ptrh1 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PTRH1 mRNA] | CTD | PMID:31150632 | Ptrh1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PTRH1 mRNA | CTD | PMID:34492290 | Ptrh1 | Rat | titanium dioxide | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of PTRH1 mRNA | CTD | PMID:23557971|PMID:27760801 | Ptrh1 | Rat | titanium dioxide | decreases methylation | ISO | Ptrh1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PTRH1 promoter alternative form | CTD | PMID:35295148 | Ptrh1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PTRH1 mRNA | CTD | PMID:33387578 | Ptrh1 | Rat | trimellitic anhydride | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of PTRH1 mRNA | CTD | PMID:19042947 | Ptrh1 | Rat | Triptolide | increases expression | ISO | Ptrh1 (Mus musculus) | 6480464 | triptolide results in increased expression of PTRH1 mRNA | CTD | PMID:32835833 | Ptrh1 | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | PTRH1 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of PTRH1 mRNA | CTD | PMID:29024780 | Ptrh1 | Rat | urethane | decreases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of PTRH1 mRNA | CTD | PMID:28818685 | Ptrh1 | Rat | valproic acid | increases methylation | ISO | PTRH1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PTRH1 gene | CTD | PMID:29154799 | Ptrh1 | Rat | valproic acid | increases expression | ISO | PTRH1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PTRH1 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:26272509|PMID:28001369 | Ptrh1 | Rat | valproic acid | multiple interactions | ISO | PTRH1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















