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Gene: Myom3 (myomesin 3) Rattus norvegicus

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Symbol:

Myom3

Name:

myomesin 3

RGD ID:

1310060

Description:

Predicted to enable protein homodimerization activity. Predicted to be involved in sarcomere organization. Predicted to be active in M band. Orthologous to human MYOM3 (myomesin 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC313625; myomesin family, member 3; myomesin-3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MYOM3 (myomesin 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Treefam
Mus musculus (house mouse):	Myom3 (myomesin family, member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Myom3 (myomesin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MYOM3 (myomesin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MYOM3 (myomesin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Myom3 (myomesin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MYOM3 (myomesin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MYOM3 (myomesin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Myom3 (myomesin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MYOM3 (myomesin 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Myom3 (myomesin family, member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	myom3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mlf1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	153,276,306 - 153,326,847 (+)	NCBI		GRCr8
mRatBN7.2	5	147,992,737 - 148,043,282 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	147,992,737 - 148,043,274 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	150,695,974 - 150,746,318 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	152,466,463 - 152,516,857 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	152,452,255 - 152,502,595 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	154,109,293 - 154,159,943 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	154,112,076 - 154,159,601 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	157,874,261 - 157,925,003 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	154,544,049 - 154,589,658 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	154,554,087 - 154,601,580 (+)	NCBI
Celera	5	146,404,136 - 146,452,055 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Myom3	Rat	3-hydroxy-3-methylglutaryl-CoA lyase deficiency		ISO	MYOM3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Deficiency of hydroxymethylglutaryl-CoA lyase	ClinVar	PMID:28492532
Myom3	Rat	Contracture		ISO	MYOM3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Contractures	ClinVar	PMID:25741868
Myom3	Rat	Diamond-Blackfan anemia		ISO	MYOM3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Diamond-Blackfan anemia	ClinVar	PMID:19061985 more ...

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Myom3	Rat	1,2-dimethylhydrazine	decreases expression	ISO	Myom3 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in decreased expression of MYOM3 mRNA	CTD	PMID:22206623
Myom3	Rat	17beta-estradiol	multiple interactions	ISO	MYOM3 (Homo sapiens)	6480464	[Estradiol co-treated with TGFB1 protein] results in increased expression of MYOM3 mRNA	CTD	PMID:30165855
Myom3	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of MYOM3 mRNA	CTD	PMID:32109520
Myom3	Rat	2,3,7,8-Tetrachlorodibenzofuran	decreases expression	EXP		6480464	2 more ...	CTD	PMID:32109520
Myom3	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	Myom3 (Mus musculus)	6480464	bisphenol S results in increased expression of MYOM3 mRNA	CTD	PMID:39298647
Myom3	Rat	4,4'-sulfonyldiphenol	decreases methylation	ISO	Myom3 (Mus musculus)	6480464	bisphenol S results in decreased methylation of MYOM3 exon	CTD	PMID:33297965
Myom3	Rat	acrylamide	decreases expression	EXP		6480464	Acrylamide results in decreased expression of MYOM3 mRNA	CTD	PMID:28959563
Myom3	Rat	aldehydo-D-glucose	multiple interactions	ISO	Myom3 (Mus musculus)	6480464	[lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MYOM3 mRNA	CTD	PMID:37567420
Myom3	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of MYOM3 mRNA	CTD	PMID:35163327
Myom3	Rat	alpha-Zearalanol	decreases expression	EXP		6480464	Zeranol results in decreased expression of MYOM3 mRNA	CTD	PMID:35163327
Myom3	Rat	aristolochic acid A	increases expression	ISO	MYOM3 (Homo sapiens)	6480464	aristolochic acid I results in increased expression of MYOM3 mRNA	CTD	PMID:33212167
Myom3	Rat	arsane	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	Arsenic results in decreased expression of MYOM3 mRNA	CTD	PMID:36720308
Myom3	Rat	arsenic atom	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	Arsenic results in decreased expression of MYOM3 mRNA	CTD	PMID:36720308
Myom3	Rat	atrazine	affects methylation	EXP		6480464	Atrazine affects the methylation of MYOM3 gene	CTD	PMID:28931070 and PMID:35440735
Myom3	Rat	benzo[a]pyrene	increases expression	ISO	Myom3 (Mus musculus)	6480464	Benzo(a)pyrene results in increased expression of MYOM3 mRNA	CTD	PMID:32417428
Myom3	Rat	benzo[a]pyrene	affects methylation	ISO	MYOM3 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of MYOM3 exon more ...	CTD	PMID:27901495 and PMID:30157460
Myom3	Rat	bisphenol A	multiple interactions	EXP		6480464	[bisphenol A co-treated with Testosterone] results in decreased expression of MYOM3 mRNA	CTD	PMID:26496021
Myom3	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of MYOM3 mRNA	CTD	PMID:36779543
Myom3	Rat	bisphenol A	decreases methylation	ISO	MYOM3 (Homo sapiens)	6480464	bisphenol A results in decreased methylation of MYOM3 gene	CTD	PMID:31601247
Myom3	Rat	bisphenol F	increases expression	ISO	Myom3 (Mus musculus)	6480464	bisphenol F results in increased expression of MYOM3 mRNA	CTD	PMID:30951980
Myom3	Rat	butanal	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	butyraldehyde results in decreased expression of MYOM3 mRNA	CTD	PMID:26079696
Myom3	Rat	carbon nanotube	affects expression	ISO	Myom3 (Mus musculus)	6480464	Nanotubes and Carbon analog affects the expression of MYOM3 mRNA	CTD	PMID:25554681
Myom3	Rat	carbon nanotube	decreases expression	ISO	Myom3 (Mus musculus)	6480464	Nanotubes and Carbon results in decreased expression of MYOM3 mRNA	CTD	PMID:25554681
Myom3	Rat	carbon nanotube	increases expression	ISO	Myom3 (Mus musculus)	6480464	Nanotubes more ...	CTD	PMID:25620056
Myom3	Rat	cefaloridine	increases expression	EXP		6480464	Cephaloridine results in increased expression of MYOM3 mRNA	CTD	PMID:18500788
Myom3	Rat	CGP 52608	multiple interactions	ISO	MYOM3 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to MYOM3 gene]	CTD	PMID:28238834
Myom3	Rat	chlorpyrifos	decreases expression	ISO	Myom3 (Mus musculus)	6480464	Chlorpyrifos results in decreased expression of MYOM3 mRNA	CTD	PMID:37019170
Myom3	Rat	chrysene	increases expression	ISO	Myom3 (Mus musculus)	6480464	chrysene results in increased expression of MYOM3 mRNA	CTD	PMID:26377693
Myom3	Rat	D-glucose	multiple interactions	ISO	Myom3 (Mus musculus)	6480464	[lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MYOM3 mRNA	CTD	PMID:37567420
Myom3	Rat	dichloroacetic acid	decreases expression	ISO	Myom3 (Mus musculus)	6480464	Dichloroacetic Acid results in decreased expression of MYOM3 mRNA	CTD	PMID:28962523
Myom3	Rat	dioxygen	multiple interactions	EXP		6480464	[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of MYOM3 mRNA	CTD	PMID:33729688
Myom3	Rat	diquat	decreases expression	ISO	Myom3 (Mus musculus)	6480464	Diquat results in decreased expression of MYOM3 mRNA	CTD	PMID:36851058
Myom3	Rat	doxorubicin	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	Doxorubicin results in decreased expression of MYOM3 mRNA	CTD	PMID:29803840
Myom3	Rat	ethanol	increases expression	ISO	Myom3 (Mus musculus)	6480464	Ethanol results in increased expression of MYOM3 mRNA	CTD	PMID:30319688
Myom3	Rat	folic acid	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	Folic Acid results in decreased expression of MYOM3 mRNA	CTD	PMID:21867686
Myom3	Rat	fructose	multiple interactions	ISO	Myom3 (Mus musculus)	6480464	[lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MYOM3 mRNA	CTD	PMID:37567420
Myom3	Rat	glucose	multiple interactions	ISO	Myom3 (Mus musculus)	6480464	[lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MYOM3 mRNA	CTD	PMID:37567420
Myom3	Rat	graphene oxide	increases expression	ISO	Myom3 (Mus musculus)	6480464	graphene oxide results in increased expression of MYOM3 mRNA	CTD	PMID:33227293
Myom3	Rat	leflunomide	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	leflunomide results in decreased expression of MYOM3 mRNA	CTD	PMID:28988120
Myom3	Rat	mono(2-ethylhexyl) phthalate	increases expression	ISO	Myom3 (Mus musculus)	6480464	mono-(2-ethylhexyl)phthalate results in increased expression of MYOM3 mRNA	CTD	PMID:22401849
Myom3	Rat	niclosamide	increases expression	ISO	MYOM3 (Homo sapiens)	6480464	Niclosamide results in increased expression of MYOM3 mRNA	CTD	PMID:36318118
Myom3	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of MYOM3 mRNA	CTD	PMID:35163327
Myom3	Rat	pioglitazone	multiple interactions	ISO	Myom3 (Mus musculus)	6480464	[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM3 mRNA	CTD	PMID:27935865
Myom3	Rat	pirinixic acid	decreases expression	ISO	Myom3 (Mus musculus)	6480464	pirinixic acid results in decreased expression of MYOM3 mRNA	CTD	PMID:23811191
Myom3	Rat	propanal	increases expression	ISO	MYOM3 (Homo sapiens)	6480464	propionaldehyde results in increased expression of MYOM3 mRNA	CTD	PMID:26079696
Myom3	Rat	propiconazole	increases expression	ISO	Myom3 (Mus musculus)	6480464	propiconazole results in increased expression of MYOM3 mRNA	CTD	PMID:21278054
Myom3	Rat	rotenone	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	Rotenone results in decreased expression of MYOM3 mRNA	CTD	PMID:29955902
Myom3	Rat	silicon dioxide	increases expression	ISO	MYOM3 (Homo sapiens)	6480464	Silicon Dioxide analog results in increased expression of MYOM3 mRNA	CTD	PMID:23806026
Myom3	Rat	silver atom	increases expression	ISO	Myom3 (Mus musculus)	6480464	Silver results in increased expression of MYOM3 mRNA	CTD	PMID:27131904
Myom3	Rat	silver(0)	increases expression	ISO	Myom3 (Mus musculus)	6480464	Silver results in increased expression of MYOM3 mRNA	CTD	PMID:27131904
Myom3	Rat	sunitinib	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	Sunitinib results in decreased expression of MYOM3 mRNA	CTD	PMID:31533062
Myom3	Rat	tamoxifen	increases expression	ISO	Myom3 (Mus musculus)	6480464	Tamoxifen results in increased expression of MYOM3 mRNA	CTD	PMID:25123088
Myom3	Rat	temozolomide	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	Temozolomide results in decreased expression of MYOM3 mRNA	CTD	PMID:31758290
Myom3	Rat	testosterone	multiple interactions	EXP		6480464	[bisphenol A co-treated with Testosterone] results in decreased expression of MYOM3 mRNA	CTD	PMID:26496021
Myom3	Rat	tetrachloroethene	decreases expression	ISO	Myom3 (Mus musculus)	6480464	Tetrachloroethylene results in decreased expression of MYOM3 mRNA	CTD	PMID:28973375
Myom3	Rat	tetrachloromethane	increases expression	EXP		6480464	Carbon Tetrachloride results in increased expression of MYOM3 mRNA	CTD	PMID:33387578
Myom3	Rat	tetraphene	decreases expression	ISO	Myom3 (Mus musculus)	6480464	benz(a)anthracene results in decreased expression of MYOM3 mRNA	CTD	PMID:26377693
Myom3	Rat	trichloroethene	decreases expression	ISO	Myom3 (Mus musculus)	6480464	Trichloroethylene results in decreased expression of MYOM3 mRNA	CTD	PMID:28973375
Myom3	Rat	triptonide	increases expression	ISO	Myom3 (Mus musculus)	6480464	triptonide results in increased expression of MYOM3 mRNA	CTD	PMID:33045310
Myom3	Rat	tris(2-butoxyethyl) phosphate	affects expression	ISO	MYOM3 (Homo sapiens)	6480464	tris(2-butoxyethyl) phosphate affects the expression of MYOM3 mRNA	CTD	PMID:29024780
Myom3	Rat	urethane	decreases expression	ISO	MYOM3 (Homo sapiens)	6480464	Urethane results in decreased expression of MYOM3 mRNA	CTD	PMID:28818685
Myom3	Rat	valproic acid	increases methylation	ISO	MYOM3 (Homo sapiens)	6480464	Valproic Acid results in increased methylation of MYOM3 gene	CTD	PMID:29154799

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Myom3	Rat	sarcomere organization	involved_in	IBA	FB:FBgn0005666 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Myom3	Rat	M band	located_in	IEA	UniProtKB:A2ABU4 and ensembl:ENSMUSP00000101480	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Myom3	Rat	M band	located_in	ISO	Myom3 (Mus musculus)	1624291	PMID:18177667 more ...	RGD	PMID:18177667 more ...
Myom3	Rat	M band	is_active_in	IBA	MGI:1328358 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Myom3	Rat	identical protein binding	enables	IEA	UniProtKB:A2ABU4 and ensembl:ENSMUSP00000101480	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Myom3	Rat	identical protein binding	enables	ISO	Myom3 (Mus musculus)	1624291	PR:A2ABU4 PMID:18177667	RGD	PMID:18177667
Myom3	Rat	protein binding	enables	ISO	MYOM3 (Homo sapiens) and UniProtKB:Q5VTT5-2	1624291	UniProtKB:Q08379 more ...	RGD	PMID:32296183
Myom3	Rat	protein homodimerization activity	enables	ISO	Myom3 (Mus musculus)	1624291	PMID:18177667	RGD	PMID:18177667
Myom3	Rat	protein homodimerization activity	enables	IEA	UniProtKB:A2ABU4 and ensembl:ENSMUSP00000101480	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:18177667	PMID:20215401	PMID:22562206

Myom3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	153,276,306 - 153,326,847 (+)	NCBI		GRCr8
mRatBN7.2	5	147,992,737 - 148,043,282 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	147,992,737 - 148,043,274 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	150,695,974 - 150,746,318 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	152,466,463 - 152,516,857 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	152,452,255 - 152,502,595 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	154,109,293 - 154,159,943 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	154,112,076 - 154,159,601 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	157,874,261 - 157,925,003 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	154,544,049 - 154,589,658 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	154,554,087 - 154,601,580 (+)	NCBI
Celera	5	146,404,136 - 146,452,055 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

MYOM3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	24,056,041 - 24,112,135 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	24,056,035 - 24,112,135 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	24,382,531 - 24,438,625 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	24,255,118 - 24,311,252 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	24,127,840 - 24,166,799	NCBI
Celera	1	22,712,351 - 22,768,155 (-)	NCBI		Celera
Cytogenetic Map	1	p36.11	NCBI
HuRef	1	22,635,721 - 22,691,562 (-)	NCBI		HuRef
CHM1_1	1	24,495,395 - 24,551,149 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	23,893,755 - 23,949,845 (-)	NCBI		T2T-CHM13v2.0

Myom3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	135,486,688 - 135,542,882 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	135,487,026 - 135,542,875 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	135,758,800 - 135,815,571 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	135,759,715 - 135,815,564 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	135,315,630 - 135,371,479 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	135,031,797 - 135,087,643 (+)	NCBI		MGSCv36	mm8
Celera	4	133,953,803 - 134,009,988 (+)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	68.0	NCBI

Myom3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	3,925,613 - 3,965,788 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	3,925,373 - 3,968,721 (-)	NCBI	ChiLan1.0	ChiLan1.0

MYOM3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	202,818,073 - 202,874,400 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	201,921,587 - 201,977,861 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	23,258,334 - 23,314,653 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	24,237,338 - 24,293,396 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	24,237,338 - 24,293,396 (-)	Ensembl	panpan1.1		panPan2

MYOM3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	75,481,191 - 75,529,559 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	75,483,897 - 75,528,402 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	72,053,115 - 72,100,851 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	76,041,598 - 76,089,846 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	76,041,613 - 76,089,765 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	72,863,965 - 72,912,213 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	73,871,249 - 73,919,337 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	74,876,301 - 74,924,495 (+)	NCBI		UU_Cfam_GSD_1.0

Myom3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	43,310,395 - 43,353,701 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	9,134,581 - 9,178,515 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	9,134,826 - 9,178,439 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MYOM3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	81,803,877 - 81,860,046 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	81,803,877 - 81,859,506 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MYOM3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	108,573,783 - 108,634,238 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	108,574,386 - 108,634,663 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	7,724,521 - 7,781,060 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Myom3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	8,549,887 - 8,596,189 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	8,550,533 - 8,596,075 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Myom3
495 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	29
Count of miRNA genes:	29
Interacting mature miRNAs:	29
Transcripts:	ENSRNOT00000044969
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
2302369	Scl60	Serum cholesterol level QTL 60	3.13		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	143608201	161165651	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	144358090	157869054	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	143799107	158428037	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	144377876	161317411	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat

D5Uwm40

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	153,296,246 - 153,296,482 (+)	Marker Load Pipeline
mRatBN7.2	5	148,012,677 - 148,012,915 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	154,129,339 - 154,129,574	NCBI	Rnor6.0
Rnor_5.0	5	157,894,342 - 157,894,577	UniSTS	Rnor5.0
Celera	5	146,421,465 - 146,421,642	UniSTS
Cytogenetic Map	5	q36	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	107	69	68	37	17	37	6	188	89	87	45	60	31


RefSeq Transcripts	NM_001107987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001372118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003750060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239278	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008776141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC135901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ126179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000044969 ⟹ ENSRNOP00000045729

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	147,992,737 - 148,043,274 (+)	Ensembl
Rnor_6.0 Ensembl	5	154,112,076 - 154,159,601 (+)	Ensembl

RefSeq Acc Id:

NM_001107987 ⟹ NP_001101457

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	153,276,306 - 153,326,847 (+)	NCBI
mRatBN7.2	5	147,992,737 - 148,043,282 (+)	NCBI

RefSeq Acc Id:

NM_001372118 ⟹ NP_001359047

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	153,276,306 - 153,326,847 (+)	NCBI
mRatBN7.2	5	147,992,737 - 148,043,282 (+)	NCBI


Protein RefSeqs	NP_001101457	(Get FASTA)	NCBI Sequence Viewer
	NP_001359047	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL80767	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000045729
	ENSRNOP00000045729.5

Ensembl Acc Id:

ENSRNOP00000045729 ⟸ ENSRNOT00000044969

RefSeq Acc Id:	NP_001101457 ⟸ NM_001107987
- Peptide Label:	isoform 1
- UniProtKB:	D4A228 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001359047 ⟸ NM_001372118
- Peptide Label:	isoform 1
- UniProtKB:	D4A228 (UniProtKB/TrEMBL)

Protein Domains

Fibronectin type-III Ig-like

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A228-F1-model_v2	AlphaFold	D4A228	1-1438	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-39533	BioCyc
Ensembl Genes	ENSRNOG00000032994	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000044969	ENTREZGENE
	ENSRNOT00000044969.6	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	FN3_sf	UniProtKB/TrEMBL
	FN_III	UniProtKB/TrEMBL
	Ig-like	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
	Striated_Muscle_Regulatory	UniProtKB/TrEMBL
NCBI Gene	313625	ENTREZGENE
PANTHER	NEURONAL IGCAM-RELATED	UniProtKB/TrEMBL
	TITIN	UniProtKB/TrEMBL
Pfam	fn3	UniProtKB/TrEMBL
	I-set	UniProtKB/TrEMBL
PhenoGen	Myom3	PhenoGen
PRINTS	FNTYPEIII	UniProtKB/TrEMBL
PROSITE	FN3	UniProtKB/TrEMBL
	IG_LIKE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000032994	RatGTEx
SMART	FN3	UniProtKB/TrEMBL
	IGc2	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	FN_III-like	UniProtKB/TrEMBL
	SSF48726	UniProtKB/TrEMBL
UniProt	D4A228	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-24	Myom3	myomesin 3	Myom3	myomesin family, member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Myom3	myomesin family, member 3	Myom3_predicted	myomesin family, member 3 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Myom3_predicted	myomesin family, member 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar