Ugt2b34 (UDP glucuronosyltransferase 2 family, polypeptide B34) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ugt2b34 (UDP glucuronosyltransferase 2 family, polypeptide B34) Rattus norvegicus
Analyze
Symbol: Ugt2b34 (Ensembl: Ugt2b10)
Name: UDP glucuronosyltransferase 2 family, polypeptide B34 (Ensembl:UDP glucuronosyltransferase 2 family, polypeptide B10)
RGD ID: 1309989
Description: ENCODES a protein that exhibits glucuronosyltransferase activity (inferred); glycosyltransferase activity (inferred); transferase activity (inferred); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; cisplatin; indole-3-methanol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC305264; UDP glucuronosyltransferase 2 family, polypeptide B10; UDP glycosyltransferase 2 family, polypeptide B10; UDP-glucuronosyltransferase 2B10; Ugt2b10
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81421,436,939 - 21,483,494 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1421,462,841 - 21,483,494 (+)EnsemblGRCr8
mRatBN7.21421,107,996 - 21,128,648 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1421,024,006 - 21,035,986 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl1421,108,006 - 21,127,828 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1421,447,268 - 21,476,568 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01422,766,204 - 22,795,506 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01421,297,288 - 21,326,588 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01422,806,132 - 22,826,890 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1422,724,070 - 22,825,444 (+)Ensemblrn6Rnor6.0
Rnor_5.01422,700,436 - 22,725,838 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41422,725,811 - 22,745,391 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1420,601,357 - 20,620,726 (+)NCBICelera
RGSC_v3.11422,726,191 - 22,745,391 (+)NCBI
Cytogenetic Map14p21NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation

Genomics

Comparative Map Data
Ugt2b34
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81421,436,939 - 21,483,494 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1421,462,841 - 21,483,494 (+)EnsemblGRCr8
mRatBN7.21421,107,996 - 21,128,648 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1421,024,006 - 21,035,986 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl1421,108,006 - 21,127,828 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1421,447,268 - 21,476,568 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01422,766,204 - 22,795,506 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01421,297,288 - 21,326,588 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01422,806,132 - 22,826,890 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1422,724,070 - 22,825,444 (+)Ensemblrn6Rnor6.0
Rnor_5.01422,700,436 - 22,725,838 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41422,725,811 - 22,745,391 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1420,601,357 - 20,620,726 (+)NCBICelera
RGSC_v3.11422,726,191 - 22,745,391 (+)NCBI
Cytogenetic Map14p21NCBI
Ugt2b34
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39587,037,613 - 87,054,805 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl587,037,626 - 87,054,796 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38586,889,770 - 86,906,937 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl586,889,767 - 86,906,937 (-)Ensemblmm10GRCm38
MGSCv37587,318,795 - 87,335,962 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36587,964,331 - 87,981,498 (-)NCBIMGSCv36mm8
Celera584,109,778 - 84,126,936 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.56NCBI

Variants

.
Variants in Ugt2b34
300 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:30
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000002728
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141787564536079022Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14939329839411170Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141133490630674469Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141133471628389666Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141891545442433608Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141889519263895192Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141790672654251504Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141513759431238250Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
mesenchyme
mesoderm
nervous system
renal system
reproductive system
sensory system
visual system
7 2 2 14 2 2 5 12 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000002724   ⟹   ENSRNOP00000002724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1421,024,035 - 21,035,784 (+)Ensembl
Rnor_6.0 Ensembl1422,724,399 - 22,736,148 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000002728   ⟹   ENSRNOP00000002728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1421,462,841 - 21,483,494 (+)Ensembl
mRatBN7.2 Ensembl1421,108,006 - 21,127,828 (+)Ensembl
Rnor_6.0 Ensembl1422,806,132 - 22,825,444 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089471   ⟹   ENSRNOP00000069054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1421,024,006 - 21,035,986 (+)Ensembl
Rnor_6.0 Ensembl1422,724,070 - 22,806,839 (+)Ensembl
RefSeq Acc Id: NM_001191676   ⟹   NP_001178605
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81421,462,841 - 21,483,494 (+)NCBI
mRatBN7.21421,107,996 - 21,128,648 (+)NCBI
Rnor_6.01422,806,132 - 22,825,444 (+)NCBI
Rnor_5.01422,700,436 - 22,725,838 (+)NCBI
Celera1420,601,357 - 20,620,726 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063273072   ⟹   XP_063129142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81421,436,939 - 21,483,480 (+)NCBI
RefSeq Acc Id: XM_063273073   ⟹   XP_063129143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81421,462,803 - 21,483,480 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178605 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129142 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129143 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002728
  ENSRNOP00000002728.2
RefSeq Acc Id: NP_001178605   ⟸   NM_001191676
- Peptide Label: precursor
- UniProtKB: D4A132 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002728   ⟸   ENSRNOT00000002728
Ensembl Acc Id: ENSRNOP00000002724   ⟸   ENSRNOT00000002724
Ensembl Acc Id: ENSRNOP00000069054   ⟸   ENSRNOT00000089471
RefSeq Acc Id: XP_063129142   ⟸   XM_063273072
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063129143   ⟸   XM_063273073
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699258
Promoter ID:EPDNEW_R9783
Type:multiple initiation site
Name:Ugt2b17_1
Description:UDP glucuronosyltransferase family 2 member B17
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9782  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01422,806,105 - 22,806,165EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309989 AgrOrtholog
BioCyc Gene G2FUF-16090 BioCyc
Ensembl Genes ENSRNOG00000001990 Ensembl
  ENSRNOG00000062781 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002728 ENTREZGENE
  ENSRNOT00000002728.4 UniProtKB/TrEMBL
Gene3D-CATH Glycogen Phosphorylase B UniProtKB/TrEMBL
InterPro UDP-glycosyltransferase UniProtKB/TrEMBL
  UDP_glucos_trans UniProtKB/TrEMBL
  UDP_glycos_trans_CS UniProtKB/TrEMBL
KEGG Report rno:305264 UniProtKB/TrEMBL
NCBI Gene 305264 ENTREZGENE
PANTHER EG:EG0003.4 PROTEIN-RELATED UniProtKB/TrEMBL
  UDP-GLUCURONOSYLTRANSFERASE UniProtKB/TrEMBL
Pfam UDPGT UniProtKB/TrEMBL
PharmGKB UGT2B10 RGD
PhenoGen Ugt2b34 PhenoGen
PROSITE UDPGT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001990 RatGTEx
  ENSRNOG00000062781 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/TrEMBL
UniProt D4A132 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-07-24 Ugt2b34  UDP glucuronosyltransferase 2 family, polypeptide B34  Ugt2b10  UDP glucuronosyltransferase 2 family, polypeptide B10  Name and Symbol changed 629549 APPROVED
2012-02-02 Ugt2b10  UDP glucuronosyltransferase 2 family, polypeptide B10  Ugt2b34  UDP glucuronosyltransferase 2 family, polypeptide B34  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Ugt2b34  UDP glucuronosyltransferase 2 family, polypeptide B34  Ugt2b10_predicted  UDP glycosyltransferase 2 family, polypeptide B10 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Ugt2b10_predicted  UDP glycosyltransferase 2 family, polypeptide B10 (predicted)      Symbol and Name status set to approved 70820 APPROVED