Symbol:
Ell3
Name:
elongation factor for RNA polymerase II 3
RGD ID:
1309917
Description:
Predicted to enable cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of transcription elongation by RNA polymerase II; regulation of epithelial to mesenchymal transition; and transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Orthologous to human ELL3 (elongation factor for RNA polymerase II 3); PARTICIPATES IN RNA polymerase II transcription elongation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acetamide.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
elongation factor RNA polymerase II-like 3; LOC296102; RNA polymerase II elongation factor ELL3
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ELL3 (elongation factor for RNA polymerase II 3)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Ell3 (elongation factor RNA polymerase II-like 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Ell3 (elongation factor for RNA polymerase II 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ELL3 (elongation factor for RNA polymerase II 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ELL3 (elongation factor for RNA polymerase II 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ell3 (elongation factor for RNA polymerase II 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ELL3 (elongation factor for RNA polymerase II 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
ELL3 (elongation factor for RNA polymerase II 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ell3 (elongation factor for RNA polymerase II 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Ell3 (elongation factor for RNA polymerase II 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
FGF1 (fibroblast growth factor 1)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
ELL3 (elongation factor for RNA polymerase II 3)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
A930015D22Rik (RIKEN cDNA A930015D22 gene)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
A930015D22Rik (RIKEN cDNA A930015D22 gene)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Su(Tpl)
Alliance
DIOPT (Ensembl Compara|OrthoInspector|PANTHER)
Mus musculus (house mouse):
Ell3 (elongation factor RNA polymerase II-like 3)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Ell3 (elongation factor RNA polymerase II-like 3)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 128,866,755 - 128,870,896 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 3 128,864,777 - 128,870,852 (-) Ensembl GRCr8 mRatBN7.2 3 108,413,035 - 108,417,181 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 108,410,448 - 108,417,132 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 3 112,087,470 - 112,091,565 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 120,682,989 - 120,687,084 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 118,343,390 - 118,347,485 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 113,400,395 - 113,405,869 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 113,401,734 - 113,405,829 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 3 119,940,838 - 119,945,974 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 3 108,241,165 - 108,245,260 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 3 107,314,256 - 107,318,351 (-) NCBI Celera RGSC_v3.1 3 108,141,954 - 108,146,050 (-) NCBI Cytogenetic Map 3 q35 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Ell3 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Ell3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ell3 Rat 17beta-estradiol multiple interactions ISO ELL3 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of ELL3 mRNA CTD PMID:30165855 Ell3 Rat 17beta-estradiol decreases expression ISO Ell3 (Mus musculus) 6480464 Estradiol results in decreased expression of ELL3 mRNA CTD PMID:39298647 Ell3 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Ell3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ell3 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Ell3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ell3 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ELL3 mRNA CTD PMID:22298810 Ell3 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ell3 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ELL3 mRNA CTD PMID:21570461|PMID:26377647 Ell3 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Ell3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ell3 Rat 2,6-dinitrotoluene affects expression EXP 6480464 2,6-dinitrotoluene affects the expression of ELL3 mRNA CTD PMID:21346803 Ell3 Rat 4,4'-sulfonyldiphenol decreases expression ISO Ell3 (Mus musculus) 6480464 bisphenol S results in decreased expression of ELL3 mRNA CTD PMID:39298647 Ell3 Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of ELL3 mRNA CTD PMID:31881176 Ell3 Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of ELL3 mRNA CTD PMID:28959563 Ell3 Rat aflatoxin B1 increases expression ISO ELL3 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of ELL3 mRNA CTD PMID:22100608 Ell3 Rat aflatoxin B1 increases expression ISO Ell3 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of ELL3 mRNA CTD PMID:19770486 Ell3 Rat all-trans-retinoic acid decreases expression ISO ELL3 (Homo sapiens) 6480464 Tretinoin results in decreased expression of ELL3 mRNA CTD PMID:33167477 Ell3 Rat arsane affects methylation ISO ELL3 (Homo sapiens) 6480464 Arsenic affects the methylation of ELL3 gene CTD PMID:25304211 Ell3 Rat arsenic atom affects methylation ISO ELL3 (Homo sapiens) 6480464 Arsenic affects the methylation of ELL3 gene CTD PMID:25304211 Ell3 Rat arsenous acid increases expression ISO Ell3 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of ELL3 mRNA CTD PMID:39716349 Ell3 Rat benzo[a]pyrene increases expression ISO Ell3 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of ELL3 mRNA CTD PMID:19770486 Ell3 Rat bis(2-chloroethyl) sulfide increases expression ISO ELL3 (Homo sapiens) 6480464 Mustard Gas results in increased expression of ELL3 mRNA CTD PMID:25102026 Ell3 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Ell3 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of ELL3 mRNA CTD PMID:34319233 Ell3 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ELL3 mRNA CTD PMID:25181051 Ell3 Rat bisphenol A multiple interactions ISO ELL3 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ELL3 gene CTD PMID:31601247 Ell3 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of ELL3 gene CTD PMID:28505145 Ell3 Rat bisphenol F decreases expression ISO Ell3 (Mus musculus) 6480464 bisphenol F results in decreased expression of ELL3 mRNA CTD PMID:38685157 Ell3 Rat buta-1,3-diene decreases expression ISO Ell3 (Mus musculus) 6480464 1,3-butadiene results in decreased expression of ELL3 mRNA CTD PMID:29038090 Ell3 Rat caffeine decreases phosphorylation ISO ELL3 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of ELL3 protein CTD PMID:35688186 Ell3 Rat carbamazepine affects expression ISO ELL3 (Homo sapiens) 6480464 Carbamazepine affects the expression of ELL3 mRNA CTD PMID:25979313 Ell3 Rat carbon nanotube decreases expression ISO Ell3 (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of ELL3 mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681|PMID:25620056 Ell3 Rat cisplatin multiple interactions ISO ELL3 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of ELL3 mRNA CTD PMID:27392435 Ell3 Rat cisplatin increases expression ISO ELL3 (Homo sapiens) 6480464 Cisplatin results in increased expression of ELL3 mRNA CTD PMID:27392435 Ell3 Rat coumarin increases expression EXP 6480464 coumarin results in increased expression of ELL3 mRNA CTD PMID:18480146 Ell3 Rat crocidolite asbestos affects expression ISO ELL3 (Homo sapiens) 6480464 Asbestos, Crocidolite affects the expression of ELL3 mRNA CTD PMID:17331233 Ell3 Rat cyclosporin A decreases expression ISO ELL3 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ELL3 mRNA CTD PMID:25562108|PMID:27989131 Ell3 Rat cyclosporin A decreases expression ISO Ell3 (Mus musculus) 6480464 Cyclosporine results in decreased expression of ELL3 mRNA CTD PMID:19770486 Ell3 Rat cypermethrin increases expression ISO ELL3 (Homo sapiens) 6480464 cypermethrin results in increased expression of ELL3 protein CTD PMID:36063984 Ell3 Rat diarsenic trioxide increases expression ISO Ell3 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of ELL3 mRNA CTD PMID:39716349 Ell3 Rat dicrotophos decreases expression ISO ELL3 (Homo sapiens) 6480464 dicrotophos results in decreased expression of ELL3 mRNA CTD PMID:28302478 Ell3 Rat doxorubicin affects response to substance ISO ELL3 (Homo sapiens) 6480464 ELL3 protein affects the susceptibility to Doxorubicin CTD PMID:16217747 Ell3 Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of ELL3 mRNA CTD PMID:29391264 Ell3 Rat entinostat increases expression ISO ELL3 (Homo sapiens) 6480464 entinostat results in increased expression of ELL3 mRNA CTD PMID:26272509 Ell3 Rat fulvestrant multiple interactions ISO ELL3 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ELL3 gene CTD PMID:31601247 Ell3 Rat furan increases expression EXP 6480464 furan results in increased expression of ELL3 mRNA CTD PMID:25539665 Ell3 Rat glafenine increases expression EXP 6480464 Glafenine results in increased expression of ELL3 mRNA CTD PMID:24136188 Ell3 Rat hydralazine multiple interactions ISO ELL3 (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in decreased expression of ELL3 mRNA CTD PMID:17183730 Ell3 Rat okadaic acid increases expression ISO ELL3 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of ELL3 mRNA CTD PMID:38832940 Ell3 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of ELL3 mRNA CTD PMID:33387578 Ell3 Rat PCB138 multiple interactions ISO Ell3 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ell3 Rat pirinixic acid multiple interactions ISO ELL3 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Ell3 Rat progesterone decreases expression ISO Ell3 (Mus musculus) 6480464 Progesterone results in decreased expression of ELL3 mRNA CTD PMID:22238285 Ell3 Rat propiconazole increases expression ISO Ell3 (Mus musculus) 6480464 propiconazole results in increased expression of ELL3 mRNA CTD PMID:21278054 Ell3 Rat silver atom increases expression ISO Ell3 (Mus musculus) 6480464 Silver results in increased expression of ELL3 mRNA CTD PMID:27131904 Ell3 Rat silver(0) increases expression ISO Ell3 (Mus musculus) 6480464 Silver results in increased expression of ELL3 mRNA CTD PMID:27131904 Ell3 Rat sodium arsenite decreases expression ISO Ell3 (Mus musculus) 6480464 sodium arsenite results in decreased expression of ELL3 mRNA CTD PMID:22700541|PMID:37682722 Ell3 Rat sodium arsenite affects expression ISO Ell3 (Mus musculus) 6480464 sodium arsenite affects the expression of ELL3 mRNA CTD PMID:25825268 Ell3 Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of ELL3 mRNA CTD PMID:34492290 Ell3 Rat topotecan affects response to substance ISO ELL3 (Homo sapiens) 6480464 ELL3 protein affects the susceptibility to Topotecan CTD PMID:16217747 Ell3 Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of ELL3 mRNA CTD PMID:33387578 Ell3 Rat valproic acid multiple interactions ISO ELL3 (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in decreased expression of ELL3 mRNA CTD PMID:17183730 Ell3 Rat valproic acid affects expression ISO ELL3 (Homo sapiens) 6480464 Valproic Acid affects the expression of ELL3 mRNA CTD PMID:25979313 Ell3 Rat valproic acid increases expression ISO ELL3 (Homo sapiens) 6480464 Valproic Acid results in increased expression of ELL3 mRNA CTD PMID:26272509|PMID:29154799 Ell3 Rat valproic acid affects expression ISO Ell3 (Mus musculus) 6480464 Valproic Acid affects the expression of ELL3 mRNA CTD PMID:17963808 Ell3 Rat vancomycin increases expression ISO Ell3 (Mus musculus) 6480464 Vancomycin results in increased expression of ELL3 mRNA CTD PMID:18930951