Cep57 (centrosomal protein 57) - Rat Genome Database

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Gene: Cep57 (centrosomal protein 57) Rattus norvegicus
Analyze
Symbol: Cep57
Name: centrosomal protein 57
RGD ID: 1309884
Description: Predicted to enable fibroblast growth factor binding activity; microtubule binding activity; and protein homodimerization activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway; protein homooligomerization; and spermatid development. Predicted to be located in Golgi apparatus; microtubule; and nucleus. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome 2. Orthologous to human CEP57 (centrosomal protein 57); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3110002l15rik; centrosomal protein 57kDa; centrosomal protein of 57 kDa; LOC315423; RGD1309884; similar to translokin; translokin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8818,951,179 - 18,971,205 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl818,932,808 - 18,970,890 (-)EnsemblGRCr8
mRatBN7.2810,669,588 - 10,689,257 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl810,669,590 - 10,689,249 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx814,656,395 - 14,676,043 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0812,954,121 - 12,973,769 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0810,930,498 - 10,950,158 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0812,335,430 - 12,355,425 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl812,335,432 - 12,355,091 (-)Ensemblrn6Rnor6.0
Rnor_5.0812,285,706 - 12,305,716 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4810,608,688 - 10,627,914 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera812,170,101 - 12,189,763 (-)NCBICelera
RGSC_v3.1810,608,258 - 10,628,586 (-)NCBI
Cytogenetic Map8q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
hydrogen peroxide  (ISO)
lead(0)  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
mitomycin C  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenytoin  (EXP)
picoxystrobin  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centriolar satellite  (IEA,ISO)
centrosome  (IBA,IEA,ISO)
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO)
Golgi apparatus  (IEA,ISO)
microtubule  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10942595   PMID:12477932   PMID:12717444   PMID:12954732   PMID:14654843   PMID:18294141   PMID:21399614  


Genomics

Comparative Map Data
Cep57
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8818,951,179 - 18,971,205 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl818,932,808 - 18,970,890 (-)EnsemblGRCr8
mRatBN7.2810,669,588 - 10,689,257 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl810,669,590 - 10,689,249 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx814,656,395 - 14,676,043 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0812,954,121 - 12,973,769 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0810,930,498 - 10,950,158 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0812,335,430 - 12,355,425 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl812,335,432 - 12,355,091 (-)Ensemblrn6Rnor6.0
Rnor_5.0812,285,706 - 12,305,716 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4810,608,688 - 10,627,914 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera812,170,101 - 12,189,763 (-)NCBICelera
RGSC_v3.1810,608,258 - 10,628,586 (-)NCBI
Cytogenetic Map8q12NCBI
CEP57
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381195,790,014 - 95,832,693 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1195,789,965 - 95,832,693 (+)Ensemblhg38GRCh38
GRCh371195,523,662 - 95,565,857 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361195,163,290 - 95,205,502 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1192,822,024 - 92,864,242 (+)NCBICelera
Cytogenetic Map11q21NCBI
HuRef1191,589,397 - 91,631,656 (+)NCBIHuRef
CHM1_11195,406,634 - 95,448,873 (+)NCBICHM1_1
T2T-CHM13v2.01195,797,407 - 95,840,118 (+)NCBIT2T-CHM13v2.0
Cep57
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39913,717,979 - 13,738,698 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl913,719,088 - 13,738,403 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38913,807,783 - 13,827,407 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl913,807,792 - 13,827,107 (-)Ensemblmm10GRCm38
MGSCv37913,612,232 - 13,631,537 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36913,558,192 - 13,577,449 (-)NCBIMGSCv36mm8
Celera911,086,224 - 11,105,529 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map93.49NCBI
Cep57
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955412670,889 - 690,016 (+)Ensembl
ChiLan1.0NW_004955412638,718 - 693,837 (+)NCBIChiLan1.0ChiLan1.0
CEP57
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2996,635,265 - 96,796,834 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11197,727,216 - 97,888,280 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01190,795,277 - 90,838,166 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11194,322,862 - 94,365,643 (+)NCBIPanPan1.1PanPan1.1panPan2
CEP57
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1215,314,290 - 5,360,474 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl215,314,449 - 5,361,154 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha215,306,946 - 5,372,017 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0215,470,572 - 5,535,631 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl215,489,231 - 5,535,379 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1215,265,268 - 5,330,343 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0215,326,888 - 5,391,987 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0215,374,577 - 5,439,676 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cep57
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494780,630,996 - 80,670,623 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367001,875,795 - 1,915,003 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367001,874,509 - 1,914,688 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CEP57
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl927,812,929 - 27,859,568 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1927,812,944 - 27,858,293 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2931,728,611 - 31,738,258 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CEP57
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1187,046,915 - 87,088,999 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl187,046,639 - 87,093,786 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604338,725,753 - 38,769,778 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cep57
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473540,647,104 - 40,670,640 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cep57
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v189,660,651 - 9,680,946 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cep57
70 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:87
Interacting mature miRNAs:105
Transcripts:ENSRNOT00000009318
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8132882639Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000009318   ⟹   ENSRNOP00000009318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl818,951,185 - 18,970,890 (-)Ensembl
mRatBN7.2 Ensembl810,669,590 - 10,689,249 (-)Ensembl
Rnor_6.0 Ensembl812,335,432 - 12,355,091 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104346   ⟹   ENSRNOP00000082973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl818,951,185 - 18,970,844 (-)Ensembl
mRatBN7.2 Ensembl810,669,590 - 10,689,249 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111369   ⟹   ENSRNOP00000085671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl818,951,185 - 18,965,833 (-)Ensembl
mRatBN7.2 Ensembl810,669,590 - 10,684,238 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000160395   ⟹   ENSRNOP00000103022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl818,932,808 - 18,970,844 (-)Ensembl
RefSeq Acc Id: NM_001108124   ⟹   NP_001101594
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,183 - 18,970,844 (-)NCBI
mRatBN7.2810,669,588 - 10,689,249 (-)NCBI
Rnor_6.0812,335,430 - 12,355,091 (-)NCBI
Rnor_5.0812,285,706 - 12,305,716 (-)NCBI
RGSC_v3.4810,608,688 - 10,627,914 (-)RGD
Celera812,170,101 - 12,189,763 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242523   ⟹   XP_006242585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,970,617 (-)NCBI
mRatBN7.2810,669,593 - 10,688,863 (-)NCBI
Rnor_6.0812,335,430 - 12,354,881 (-)NCBI
Rnor_5.0812,285,706 - 12,305,716 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242524   ⟹   XP_006242586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,971,205 (-)NCBI
mRatBN7.2810,669,593 - 10,689,243 (-)NCBI
Rnor_6.0812,335,430 - 12,355,425 (-)NCBI
Rnor_5.0812,285,706 - 12,305,716 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039081340   ⟹   XP_038937268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,971,205 (-)NCBI
mRatBN7.2810,669,593 - 10,687,581 (-)NCBI
RefSeq Acc Id: XM_039081341   ⟹   XP_038937269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,963,030 (-)NCBI
mRatBN7.2810,669,588 - 10,681,451 (-)NCBI
RefSeq Acc Id: XM_039081342   ⟹   XP_038937270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,963,242 (-)NCBI
mRatBN7.2810,669,588 - 10,681,643 (-)NCBI
RefSeq Acc Id: XM_039081343   ⟹   XP_038937271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,963,024 (-)NCBI
mRatBN7.2810,669,588 - 10,681,449 (-)NCBI
RefSeq Acc Id: XM_039081348   ⟹   XP_038937276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,963,242 (-)NCBI
mRatBN7.2810,669,588 - 10,681,643 (-)NCBI
RefSeq Acc Id: XM_063265328   ⟹   XP_063121398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8818,951,179 - 18,970,337 (-)NCBI
RefSeq Acc Id: NP_001101594   ⟸   NM_001108124
- UniProtKB: B4F7A7 (UniProtKB/Swiss-Prot),   A6JN77 (UniProtKB/TrEMBL),   A0A8I6A259 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242586   ⟸   XM_006242524
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A259 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242585   ⟸   XM_006242523
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A259 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009318   ⟸   ENSRNOT00000009318
RefSeq Acc Id: XP_038937270   ⟸   XM_039081342
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038937276   ⟸   XM_039081348
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038937269   ⟸   XM_039081341
- Peptide Label: isoform X3
- UniProtKB: A6JN79 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937271   ⟸   XM_039081343
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038937268   ⟸   XM_039081340
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A259 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085671   ⟸   ENSRNOT00000111369
Ensembl Acc Id: ENSRNOP00000082973   ⟸   ENSRNOT00000104346
RefSeq Acc Id: XP_063121398   ⟸   XM_063265328
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A259 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000103022   ⟸   ENSRNOT00000160395
Protein Domains
Cep57 centrosome localisation   Cep57 centrosome microtubule-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B4F7A7-F1-model_v2 AlphaFold B4F7A7 1-499 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695744
Promoter ID:EPDNEW_R6266
Type:initiation region
Name:Cep57_1
Description:centrosomal protein 57
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0812,355,123 - 12,355,183EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309884 AgrOrtholog
BioCyc Gene G2FUF-31706 BioCyc
Ensembl Genes ENSRNOG00000006792 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009318 ENTREZGENE
  ENSRNOT00000009318.7 UniProtKB/Swiss-Prot
  ENSRNOT00000111369 ENTREZGENE
Gene3D-CATH 1.20.58.90 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7113445 IMAGE-MGC_LOAD
InterPro Centrosomal_MT-associated UniProtKB/Swiss-Prot
  Cep57_CLD UniProtKB/Swiss-Prot
  Cep57_MT-bd_dom UniProtKB/Swiss-Prot
KEGG Report rno:315423 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94956 IMAGE-MGC_LOAD
NCBI Gene 315423 ENTREZGENE
PANTHER PTHR19336:SF11 UniProtKB/Swiss-Prot
  UNCHARACTERIZED DUF1167 UniProtKB/Swiss-Prot
Pfam Cep57_CLD UniProtKB/Swiss-Prot
  Cep57_MT_bd UniProtKB/Swiss-Prot
PhenoGen Cep57 PhenoGen
RatGTEx ENSRNOG00000006792 RatGTEx
UniProt A0A8I6A259 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GA59_RAT UniProtKB/TrEMBL
  A0ABK0L2N4_RAT UniProtKB/TrEMBL
  A6JN77 ENTREZGENE, UniProtKB/TrEMBL
  A6JN79 ENTREZGENE, UniProtKB/TrEMBL
  B4F7A7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-04-27 Cep57  centrosomal protein 57  Cep57  centrosomal protein 57kDa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-29 Cep57  centrosomal protein 57kDa  Cep57  centrosomal protein 57  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Cep57  centrosomal protein 57  RGD1309884  similar to translokin  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1309884  similar to translokin  RGD1309884_predicted  similar to translokin (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309884_predicted  similar to translokin (predicted)  LOC315423_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC315423_predicted  similar to translokin (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL