Gfm2 (GTP dependent ribosome recycling factor mitochondrial 2) - Rat Genome Database

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Gene: Gfm2 (GTP dependent ribosome recycling factor mitochondrial 2) Rattus norvegicus
Analyze
Symbol: Gfm2
Name: GTP dependent ribosome recycling factor mitochondrial 2
RGD ID: 1309854
Description: Predicted to enable GTPase activity. Predicted to be involved in mitochondrial translation and ribosome disassembly. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 39. Orthologous to human GFM2 (GTP dependent ribosome recycling factor mitochondrial 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EF-G2mt; elongation factor G 2, mitochondrial; G elongation factor, mitochondrial 2; LOC294672; mEF-G 2; RGD1309854; ribosome-releasing factor 2, mitochondrial; RRF2mt; similar to A930009M04Rik protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8230,184,063 - 30,222,811 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl230,184,115 - 30,222,806 (+)EnsemblGRCr8
mRatBN7.2228,449,452 - 28,488,200 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl228,449,517 - 28,488,197 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx235,503,371 - 35,538,042 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0233,597,709 - 33,632,380 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0228,411,454 - 28,446,117 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0227,949,195 - 27,984,045 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,949,208 - 27,984,256 (+)Ensemblrn6Rnor6.0
Rnor_5.0247,060,093 - 47,094,934 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4227,618,278 - 27,649,505 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera224,491,429 - 24,526,041 (+)NCBICelera
RGSC_v3.1227,538,637 - 27,568,922 (+)NCBI
Cytogenetic Map2q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:18614015   PMID:19716793  


Genomics

Comparative Map Data
Gfm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8230,184,063 - 30,222,811 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl230,184,115 - 30,222,806 (+)EnsemblGRCr8
mRatBN7.2228,449,452 - 28,488,200 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl228,449,517 - 28,488,197 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx235,503,371 - 35,538,042 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0233,597,709 - 33,632,380 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0228,411,454 - 28,446,117 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0227,949,195 - 27,984,045 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,949,208 - 27,984,256 (+)Ensemblrn6Rnor6.0
Rnor_5.0247,060,093 - 47,094,934 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4227,618,278 - 27,649,505 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera224,491,429 - 24,526,041 (+)NCBICelera
RGSC_v3.1227,538,637 - 27,568,922 (+)NCBI
Cytogenetic Map2q12NCBI
GFM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38574,721,206 - 74,767,117 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl574,721,206 - 74,767,147 (-)Ensemblhg38GRCh38
GRCh37574,017,031 - 74,062,942 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,052,787 - 74,098,798 (-)NCBIBuild 36Build 36hg18NCBI36
Celera569,911,787 - 69,957,794 (-)NCBICelera
Cytogenetic Map5q13.3NCBI
HuRef569,221,970 - 69,268,174 (-)NCBIHuRef
CHM1_1573,449,890 - 73,496,044 (-)NCBICHM1_1
T2T-CHM13v2.0575,202,108 - 75,248,032 (-)NCBIT2T-CHM13v2.0
Gfm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391397,274,445 - 97,317,710 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1397,274,445 - 97,317,703 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381397,137,933 - 97,181,202 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1397,137,937 - 97,181,195 (+)Ensemblmm10GRCm38
MGSCv371397,907,892 - 97,951,151 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361398,238,739 - 98,277,150 (+)NCBIMGSCv36mm8
Celera13100,771,320 - 100,814,229 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.66NCBI
Gfm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,904,020 - 25,942,376 (+)Ensembl
ChiLan1.0NW_00495542525,904,020 - 25,942,384 (+)NCBIChiLan1.0ChiLan1.0
GFM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2440,544,985 - 40,590,872 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1538,698,620 - 38,744,507 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0540,543,368 - 40,589,478 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1541,153,714 - 41,199,765 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl541,153,714 - 41,204,297 (+)EnsemblpanPan2panpan1.1
GFM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1257,248,610 - 57,304,148 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl257,248,610 - 57,304,102 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha254,228,827 - 54,290,619 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0257,775,262 - 57,837,411 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl257,775,268 - 57,837,358 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1254,839,331 - 54,901,649 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0255,602,440 - 55,664,498 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0256,499,647 - 56,561,816 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gfm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213188,940,289 - 188,985,288 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365491,873,694 - 1,918,221 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365491,873,700 - 1,918,371 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GFM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl283,779,439 - 83,843,839 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1283,770,518 - 83,843,896 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,358,245 - 85,429,308 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GFM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,065,841 - 69,114,724 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl469,066,293 - 69,114,508 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604917,843,732 - 17,892,518 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gfm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624924148,836 - 195,123 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624924142,424 - 195,426 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Gfm2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13199,447,019 - 199,483,030 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gfm2
244 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:55
Count of miRNA genes:46
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000052072
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2142977529Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
9590080Insglur4Insulin/glucose ratio QTL 428.70.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)2615276751152767Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
731166Mamtr2Mammary tumor resistance QTL 20.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358154623581Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22888999173889991Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358144538110Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)2573632550736325Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat

Markers in Region
RH127734  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2228,487,833 - 28,488,039 (+)MAPPERmRatBN7.2
Rnor_6.0227,987,762 - 27,987,967NCBIRnor6.0
Rnor_5.0247,098,651 - 47,098,856UniSTSRnor5.0
RGSC_v3.4227,653,025 - 27,653,230UniSTSRGSC3.4
Celera224,529,758 - 24,529,963UniSTS
RH 3.4 Map231.5UniSTS
Cytogenetic Map2q12UniSTS
BE120179  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2228,483,416 - 28,483,568 (+)MAPPERmRatBN7.2
Rnor_6.0227,983,345 - 27,983,496NCBIRnor6.0
Rnor_5.0247,094,234 - 47,094,385UniSTSRnor5.0
RGSC_v3.4227,648,608 - 27,648,759UniSTSRGSC3.4
Celera224,525,341 - 24,525,492UniSTS
RH 3.4 Map229.4UniSTS
Cytogenetic Map2q12UniSTS
RH139614  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2228,485,225 - 28,485,408 (+)MAPPERmRatBN7.2
Rnor_6.0227,985,154 - 27,985,336NCBIRnor6.0
Rnor_5.0247,096,043 - 47,096,225UniSTSRnor5.0
RGSC_v3.4227,650,417 - 27,650,599UniSTSRGSC3.4
Celera224,527,150 - 24,527,332UniSTS
RH 3.4 Map230.3UniSTS
Cytogenetic Map2q12UniSTS
RH140471  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2228,485,225 - 28,485,331 (+)MAPPERmRatBN7.2
Rnor_6.0227,985,154 - 27,985,259NCBIRnor6.0
Rnor_5.0247,096,043 - 47,096,148UniSTSRnor5.0
RGSC_v3.4227,650,417 - 27,650,522UniSTSRGSC3.4
Celera224,527,150 - 24,527,255UniSTS
Cytogenetic Map2q12UniSTS
RH136262  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21143,362,672 - 43,362,889 (+)MAPPERmRatBN7.2
mRatBN7.2228,447,532 - 28,447,820 (+)MAPPERmRatBN7.2
Rnor_6.0227,947,229 - 27,947,516NCBIRnor6.0
Rnor_6.01145,461,007 - 45,461,223NCBIRnor6.0
Rnor_5.01148,653,758 - 48,653,974UniSTSRnor5.0
Rnor_5.0247,058,118 - 47,058,405UniSTSRnor5.0
RGSC_v3.4227,611,987 - 27,612,274UniSTSRGSC3.4
RGSC_v3.41144,286,489 - 44,286,705UniSTSRGSC3.4
Celera1143,152,298 - 43,152,514UniSTS
Celera224,489,450 - 24,489,737UniSTS
Cytogenetic Map11q12UniSTS
Cytogenetic Map2q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000052072   ⟹   ENSRNOP00000043087
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl230,184,115 - 30,218,734 (+)Ensembl
mRatBN7.2 Ensembl228,449,531 - 28,484,127 (+)Ensembl
Rnor_6.0 Ensembl227,949,208 - 27,984,039 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080551   ⟹   ENSRNOP00000071947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl230,184,123 - 30,222,806 (+)Ensembl
mRatBN7.2 Ensembl228,449,517 - 28,488,197 (+)Ensembl
Rnor_6.0 Ensembl227,952,129 - 27,984,256 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100548   ⟹   ENSRNOP00000092183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl230,184,123 - 30,222,806 (+)Ensembl
mRatBN7.2 Ensembl228,449,517 - 28,488,197 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113513   ⟹   ENSRNOP00000086144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl230,184,123 - 30,222,806 (+)Ensembl
mRatBN7.2 Ensembl228,449,517 - 28,488,197 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120004   ⟹   ENSRNOP00000097071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl230,184,146 - 30,221,096 (+)Ensembl
mRatBN7.2 Ensembl228,456,779 - 28,488,197 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000166369   ⟹   ENSRNOP00000103345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl230,184,146 - 30,211,123 (+)Ensembl
RefSeq Acc Id: NM_001100665   ⟹   NP_001094135
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8230,184,123 - 30,218,728 (+)NCBI
mRatBN7.2228,449,512 - 28,484,117 (+)NCBI
Rnor_6.0227,949,208 - 27,984,045 (+)NCBI
Rnor_5.0247,060,093 - 47,094,934 (+)NCBI
Celera224,491,429 - 24,526,041 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231830   ⟹   XP_006231892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8230,184,122 - 30,222,811 (+)NCBI
mRatBN7.2228,449,524 - 28,488,200 (+)NCBI
Rnor_6.0227,949,216 - 27,984,045 (+)NCBI
Rnor_5.0247,060,093 - 47,094,934 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017590700   ⟹   XP_017446189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8230,184,063 - 30,222,811 (+)NCBI
mRatBN7.2228,449,452 - 28,488,200 (+)NCBI
Rnor_6.0227,949,195 - 27,984,045 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063281491   ⟹   XP_063137561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8230,184,063 - 30,208,781 (+)NCBI
RefSeq Acc Id: NP_001094135   ⟸   NM_001100665
- UniProtKB: Q5BJP6 (UniProtKB/Swiss-Prot),   A0A0G2K1R1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231892   ⟸   XM_006231830
- Peptide Label: isoform X1
- UniProtKB: Q5BJP6 (UniProtKB/Swiss-Prot),   A0A0G2K1R1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446189   ⟸   XM_017590700
- Peptide Label: isoform X2
- UniProtKB: Q5BJP6 (UniProtKB/Swiss-Prot),   A0A8I6A4R7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071947   ⟸   ENSRNOT00000080551
Ensembl Acc Id: ENSRNOP00000043087   ⟸   ENSRNOT00000052072
Ensembl Acc Id: ENSRNOP00000086144   ⟸   ENSRNOT00000113513
Ensembl Acc Id: ENSRNOP00000092183   ⟸   ENSRNOT00000100548
Ensembl Acc Id: ENSRNOP00000097071   ⟸   ENSRNOT00000120004
RefSeq Acc Id: XP_063137561   ⟸   XM_063281491
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000103345   ⟸   ENSRNOT00000166369
Protein Domains
tr-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BJP6-F1-model_v2 AlphaFold Q5BJP6 1-779 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691086
Promoter ID:EPDNEW_R1611
Type:initiation region
Name:Gfm2_1
Description:G elongation factor, mitochondrial 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0227,949,208 - 27,949,268EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309854 AgrOrtholog
BioCyc Gene G2FUF-54762 BioCyc
Ensembl Genes ENSRNOG00000025285 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000052072 ENTREZGENE
  ENSRNOT00000080551 ENTREZGENE
  ENSRNOT00000113513 ENTREZGENE
  ENSRNOT00000166369 ENTREZGENE
Gene3D-CATH 3.30.230.10 UniProtKB/Swiss-Prot
  3.30.70.240 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  Elongation Factor G (Translational Gtpase), domain 3 UniProtKB/Swiss-Prot
  Translation factors UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7322203 IMAGE-MGC_LOAD
InterPro EF-G-like_DII UniProtKB/Swiss-Prot
  EFG2 UniProtKB/Swiss-Prot
  EFG_II UniProtKB/Swiss-Prot
  EFG_III UniProtKB/Swiss-Prot
  EFG_III/V UniProtKB/Swiss-Prot
  EFG_V UniProtKB/Swiss-Prot
  EFG_V-like UniProtKB/Swiss-Prot
  G_TR_CS UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot
  Ribosomal_S5_D2-typ_fold_subgr UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  TF_GTP-bd_dom UniProtKB/Swiss-Prot
  Transl_B-barrel_sf UniProtKB/Swiss-Prot
  Transl_elong_EFG/EF2_IV UniProtKB/Swiss-Prot
MGC_CLONE MGC:109483 IMAGE-MGC_LOAD
NCBI Gene 294672 ENTREZGENE
PANTHER RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL UniProtKB/Swiss-Prot
  TRANSLATION ELONGATION FACTOR G-RELATED UniProtKB/Swiss-Prot
Pfam EF-G_D2 UniProtKB/Swiss-Prot
  EFG_C UniProtKB/Swiss-Prot
  EFG_II UniProtKB/Swiss-Prot
  EFG_IV UniProtKB/Swiss-Prot
  GTP_EFTU UniProtKB/Swiss-Prot
PhenoGen Gfm2 PhenoGen
PRINTS ELONGATNFCT UniProtKB/Swiss-Prot
PROSITE G_TR_1 UniProtKB/Swiss-Prot
  G_TR_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000025285 RatGTEx
SMART EFG_C UniProtKB/Swiss-Prot
  EFG_IV UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50447 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
  SSF54211 UniProtKB/Swiss-Prot
  SSF54980 UniProtKB/Swiss-Prot
UniProt A0A0G2K1R1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A4R7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ARZ7_RAT UniProtKB/TrEMBL
  A0A8I6AVC4_RAT UniProtKB/TrEMBL
  A0ABK0L325_RAT UniProtKB/TrEMBL
  F1LMZ4_RAT UniProtKB/TrEMBL
  Q5BJP6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-17 Gfm2  GTP dependent ribosome recycling factor mitochondrial 2  Gfm2  G elongation factor, mitochondrial 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Gfm2  G elongation factor, mitochondrial 2  RGD1309854  similar to A930009M04Rik protein  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1309854  similar to A930009M04Rik protein  RGD1309854_predicted  similar to A930009M04Rik protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309854_predicted  similar to A930009M04Rik protein (predicted)  LOC294672_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC294672_predicted  similar to A930009M04Rik protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL