Fam13a (family with sequence similarity 13, member A) - Rat Genome Database

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Gene: Fam13a (family with sequence similarity 13, member A) Rattus norvegicus
Analyze
Symbol: Fam13a
Name: family with sequence similarity 13, member A
RGD ID: 1309807
Description: Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Orthologous to human FAM13A (family with sequence similarity 13 member A); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fam13a1; family with sequence similarity 13, member A1; LOC362378; RGD1309807; similar to Fam13a1 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8489,386,685 - 89,485,940 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl489,388,569 - 89,485,988 (-)EnsemblGRCr8
mRatBN7.2488,056,521 - 88,155,782 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl488,058,403 - 88,155,860 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx493,273,587 - 93,363,971 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0489,048,913 - 89,139,301 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0487,417,969 - 87,508,283 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0489,183,180 - 89,281,282 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl489,183,768 - 89,281,222 (-)Ensemblrn6Rnor6.0
Rnor_5.04154,004,233 - 154,102,174 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4487,832,159 - 87,931,440 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera482,818,563 - 82,909,197 (-)NCBICelera
RGSC_v3.1488,076,739 - 88,413,374 (-)NCBI
Cytogenetic Map4q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4,5,3',4',5'-Hexachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
Alisol A  (EXP)
Alisol B  (EXP)
Alisol C 23-acetate  (EXP)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
amphotericin B  (ISO)
aristolochic acid A  (ISO)
atrazine  (EXP)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromuconazole  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP,ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
hydroquinone  (ISO)
indole-3-methanol  (EXP)
methapyrilene  (ISO)
methylisothiazolinone  (ISO)
Muraglitazar  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
resorcinol  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (EXP)
valproic acid  (ISO)
vandetanib  (ISO)
vorinostat  (ISO)
zinc sulfate  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline. Xie J, etal., Respir Res. 2015 Apr 18;16:49. doi: 10.1186/s12931-015-0209-3.
Additional References at PubMed
PMID:12477932   PMID:31164635  


Genomics

Comparative Map Data
Fam13a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8489,386,685 - 89,485,940 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl489,388,569 - 89,485,988 (-)EnsemblGRCr8
mRatBN7.2488,056,521 - 88,155,782 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl488,058,403 - 88,155,860 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx493,273,587 - 93,363,971 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0489,048,913 - 89,139,301 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0487,417,969 - 87,508,283 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0489,183,180 - 89,281,282 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl489,183,768 - 89,281,222 (-)Ensemblrn6Rnor6.0
Rnor_5.04154,004,233 - 154,102,174 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4487,832,159 - 87,931,440 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera482,818,563 - 82,909,197 (-)NCBICelera
RGSC_v3.1488,076,739 - 88,413,374 (-)NCBI
Cytogenetic Map4q24NCBI
FAM13A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38488,725,960 - 89,057,185 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl488,725,955 - 89,111,398 (-)Ensemblhg38GRCh38
GRCh37489,647,111 - 89,978,336 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36489,866,129 - 90,197,346 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34490,004,283 - 90,335,501NCBI
Celera486,943,498 - 87,274,311 (-)NCBICelera
Cytogenetic Map4q22.1NCBI
HuRef485,399,481 - 85,730,241 (-)NCBIHuRef
CHM1_1489,623,576 - 89,954,831 (-)NCBICHM1_1
T2T-CHM13v2.0492,057,646 - 92,388,672 (-)NCBIT2T-CHM13v2.0
Fam13a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39658,910,521 - 59,001,487 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl658,909,075 - 59,001,534 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38658,933,536 - 59,024,502 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl658,932,090 - 59,024,549 (-)Ensemblmm10GRCm38
MGSCv37658,883,530 - 58,974,496 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36658,863,114 - 58,954,080 (-)NCBIMGSCv36mm8
Celera661,088,076 - 61,179,058 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.93NCBI
Fam13a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547411,614,830 - 11,714,369 (+)Ensembl
ChiLan1.0NW_00495547411,615,090 - 11,712,766 (+)NCBIChiLan1.0ChiLan1.0
FAM13A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2386,729,819 - 87,114,365 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1486,989,369 - 87,376,674 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0481,015,773 - 81,400,333 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1491,737,772 - 92,120,959 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl491,739,953 - 92,067,415 (-)EnsemblpanPan2panpan1.1
FAM13A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13211,993,628 - 12,313,165 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3211,998,114 - 12,338,803 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3229,642,645 - 29,961,167 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03212,047,048 - 12,365,873 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3212,049,316 - 12,392,190 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13212,133,847 - 12,452,123 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03211,954,739 - 12,300,037 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03227,643,037 - 27,962,820 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fam13a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530129,054,689 - 29,380,341 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366851,171,584 - 1,501,074 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366851,174,072 - 1,358,441 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM13A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8130,021,643 - 130,327,729 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.18130,021,581 - 130,327,731 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28139,674,434 - 139,737,982 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FAM13A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1737,086,367 - 37,458,649 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl737,085,592 - 37,406,913 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603715,844,653 - 16,220,101 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam13a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475716,415,981 - 16,502,956 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475716,414,473 - 16,763,716 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fam13a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1682,912,226 - 82,969,162 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fam13a
567 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:37
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000010898
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)480212111119233320Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)471647492116647492Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)480216705104243248Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)488883695133883695Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)469036742114036742Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)488883695133883695Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
2306794Ean2Experimental allergic neuritis QTL 26.4nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)48279077797183061Rat
2306547Iddm38Insulin dependent diabetes mellitus QTL 38blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)468353567113353567Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)486058928131411333Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)46104105794638356Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)464209744109209744Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45807987592690793Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486583980131583980Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463224393108224393Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 71 59 6 335 171 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010898   ⟹   ENSRNOP00000010898
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl489,388,569 - 89,485,904 (-)Ensembl
mRatBN7.2 Ensembl488,058,403 - 88,155,745 (-)Ensembl
Rnor_6.0 Ensembl489,183,768 - 89,281,222 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096994   ⟹   ENSRNOP00000083352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl489,388,569 - 89,485,904 (-)Ensembl
mRatBN7.2 Ensembl488,058,403 - 88,109,839 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098445   ⟹   ENSRNOP00000082991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl489,388,569 - 89,485,904 (-)Ensembl
mRatBN7.2 Ensembl488,058,403 - 88,155,745 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112072   ⟹   ENSRNOP00000083611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl489,388,569 - 89,485,988 (-)Ensembl
mRatBN7.2 Ensembl488,058,403 - 88,155,860 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133594   ⟹   ENSRNOP00000102414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl489,388,569 - 89,485,961 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000161367   ⟹   ENSRNOP00000110874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl489,389,706 - 89,485,904 (-)Ensembl
RefSeq Acc Id: NM_001100862   ⟹   NP_001094332
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8489,388,569 - 89,485,904 (-)NCBI
mRatBN7.2488,058,403 - 88,155,745 (-)NCBI
Rnor_6.0489,185,064 - 89,281,222 (-)NCBI
Rnor_5.04154,004,233 - 154,102,174 (-)NCBI
Celera482,818,563 - 82,909,197 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006236586   ⟹   XP_006236648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8489,386,685 - 89,485,939 (-)NCBI
mRatBN7.2488,056,521 - 88,155,782 (-)NCBI
Rnor_6.0489,183,180 - 89,281,281 (-)NCBI
Rnor_5.04154,004,233 - 154,102,174 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008762964   ⟹   XP_008761186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8489,386,685 - 89,485,940 (-)NCBI
mRatBN7.2488,056,521 - 88,155,782 (-)NCBI
Rnor_6.0489,183,180 - 89,281,282 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039107803   ⟹   XP_038963731
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8489,386,685 - 89,485,939 (-)NCBI
mRatBN7.2488,056,521 - 88,155,782 (-)NCBI
RefSeq Acc Id: XM_063286280   ⟹   XP_063142350
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8489,386,685 - 89,485,940 (-)NCBI
RefSeq Acc Id: NP_001094332   ⟸   NM_001100862
- UniProtKB: D3ZA02 (UniProtKB/TrEMBL),   A6K145 (UniProtKB/TrEMBL),   A0A8I5ZUY8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236648   ⟸   XM_006236586
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GAZ0 (UniProtKB/TrEMBL),   A0A8I5ZUY8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761186   ⟸   XM_008762964
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUY8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010898   ⟸   ENSRNOT00000010898
RefSeq Acc Id: XP_038963731   ⟸   XM_039107803
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZUY8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082991   ⟸   ENSRNOT00000098445
Ensembl Acc Id: ENSRNOP00000083352   ⟸   ENSRNOT00000096994
Ensembl Acc Id: ENSRNOP00000083611   ⟸   ENSRNOT00000112072
RefSeq Acc Id: XP_063142350   ⟸   XM_063286280
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZUY8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110874   ⟸   ENSRNOT00000161367
Ensembl Acc Id: ENSRNOP00000102414   ⟸   ENSRNOT00000133594

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZA02-F1-model_v2 AlphaFold D3ZA02 1-692 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693090
Promoter ID:EPDNEW_R3615
Type:initiation region
Name:Fam13a_1
Description:family with sequence similarity 13, member A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0489,281,168 - 89,281,228EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309807 AgrOrtholog
BioCyc Gene G2FUF-44652 BioCyc
Ensembl Genes ENSRNOG00000007947 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010898 ENTREZGENE
  ENSRNOT00000010898.9 UniProtKB/TrEMBL
  ENSRNOT00000096994.2 UniProtKB/TrEMBL
  ENSRNOT00000098445.2 UniProtKB/TrEMBL
  ENSRNOT00000112072 ENTREZGENE
  ENSRNOT00000112072.2 UniProtKB/TrEMBL
  ENSRNOT00000133594.1 UniProtKB/TrEMBL
  ENSRNOT00000161367.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7323947 IMAGE-MGC_LOAD
InterPro FAM13 UniProtKB/TrEMBL
KEGG Report rno:362378 UniProtKB/TrEMBL
MGC_CLONE MGC:108995 IMAGE-MGC_LOAD
NCBI Gene 362378 ENTREZGENE
PANTHER PROTEIN FAM13A UniProtKB/TrEMBL
  PTHR15904 UniProtKB/TrEMBL
PhenoGen Fam13a PhenoGen
RatGTEx ENSRNOG00000007947 RatGTEx
UniProt A0A8I5ZUY8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZV98_RAT UniProtKB/TrEMBL
  A0A8I6GAZ0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LGK6_RAT UniProtKB/TrEMBL
  A0ABK0M5R1_RAT UniProtKB/TrEMBL
  A6K145 ENTREZGENE, UniProtKB/TrEMBL
  D3ZA02 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Fam13a  family with sequence similarity 13, member A  Fam13a1  family with sequence similarity 13, member A1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-22 Fam13a1  family with sequence similarity 13, member A1  Fam13a  family with sequence similarity 13, member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-13 Fam13a  family with sequence similarity 13, member A  Fam13a1  family with sequence similarity 13, member A1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-02 Fam13a1  family with sequence similarity 13, member A1  RGD1309807  similar to Fam13a1 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1309807  similar to Fam13a1 protein  RGD1309807_predicted  similar to Fam13a1 protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309807_predicted  similar to Fam13a1 protein (predicted)  LOC362378_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362378_predicted  similar to Fam13a1 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL