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Gene: Tprkb (Tp53rk binding protein) Rattus norvegicus

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Symbol:

Tprkb

Name:

Tp53rk binding protein

RGD ID:

1309786

Description:

Predicted to enable protein kinase binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to be located in cytoplasm. Predicted to be part of EKC/KEOPS complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 5. Orthologous to human TPRKB (TP53RK binding protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Cgi-121; EKC/KEOPS complex subunit Tprkb; LOC100910911; LOC103690067; LOC297411; Prpk (p53-related protein kinase)-binding protein; RGD1309786; similar to CGI-121 protein; TP53RK-binding protein; TP53RK-binding protein-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TPRKB (TP53RK binding protein)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Tprkb (Tp53rk binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tprkb (TP53RK binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TPRKB (TP53RK binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TPRKB (TP53RK binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tprkb (TP53RK binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TPRKB (TP53RK binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TPRKB (TP53RK binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tprkb (TP53RK binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tprkb (Tp53rk binding protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TPRKB (TP53RK binding protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tprkb (Tp53rk binding protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CGI121	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	CGI121	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	W03F8.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tprkb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tprkb	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	119,900,374 - 119,915,374 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	119,900,484 - 119,915,382 (+)	Ensembl				GRCr8
mRatBN7.2	4	118,342,910 - 118,357,908 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	118,342,945 - 118,357,901 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	123,817,006 - 123,830,492 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	119,591,750 - 119,605,236 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	118,211,443 - 118,224,929 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	117,589,527 - 117,604,481 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	117,780,533 - 117,785,941 (+)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	4	117,589,591 - 117,603,155 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	182,345,035 - 182,359,990 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	120,066,138 - 120,079,624 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	107,316,394 - 107,329,878 (+)	NCBI		Celera
RGSC_v3.1	4	120,315,812 - 120,324,100 (+)	NCBI
Cytogenetic Map	4	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Galloway-Mowat syndrome (ISO)

Galloway-Mowat syndrome 5 (ISO)

nephrotic syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

clofibrate (ISO)

cobalt dichloride (EXP)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

disodium selenite (ISO)

disulfiram (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

furan (EXP)

gentamycin (EXP)

hydrogen cyanide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

ozone (ISO)

paracetamol (EXP)

pirinixic acid (ISO)

potassium cyanide (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

resveratrol (ISO)

rotenone (ISO)

sodium arsenite (ISO)

tetrachloromethane (ISO)

thimerosal (ISO)

thioacetamide (EXP)

triptonide (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

tRNA processing (IEA)

tRNA threonylcarbamoyladenosine modification (IBA,ISO,ISS)

Cellular Component

cytoplasm (ISO,ISS)

cytosol (IBA,IEA,ISO)

EKC/KEOPS complex (IBA,ISO,ISS)

nucleus (IBA,IEA,ISO,ISS)

Molecular Function

protein binding (ISO)

protein kinase binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:12659830	PMID:15489334	PMID:27903914	PMID:28805828

Genomics

Comparative Map Data

Tprkb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	119,900,374 - 119,915,374 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	119,900,484 - 119,915,382 (+)	Ensembl				GRCr8
mRatBN7.2	4	118,342,910 - 118,357,908 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	118,342,945 - 118,357,901 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	123,817,006 - 123,830,492 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	119,591,750 - 119,605,236 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	118,211,443 - 118,224,929 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	117,589,527 - 117,604,481 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	117,780,533 - 117,785,941 (+)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	4	117,589,591 - 117,603,155 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	182,345,035 - 182,359,990 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	120,066,138 - 120,079,624 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	107,316,394 - 107,329,878 (+)	NCBI		Celera
RGSC_v3.1	4	120,315,812 - 120,324,100 (+)	NCBI
Cytogenetic Map	4	q34	NCBI

TPRKB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	73,729,873 - 73,737,345 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	73,729,104 - 73,737,421 (-)	Ensembl			hg38	GRCh38
GRCh37	2	73,957,000 - 73,964,472 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	73,810,509 - 73,818,021 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	2	73,807,816 - 73,815,378 (-)	NCBI		Celera
Cytogenetic Map	2	p13.1	NCBI
HuRef	2	73,691,923 - 73,699,485 (-)	NCBI		HuRef
CHM1_1	2	73,887,711 - 73,895,270 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	73,742,992 - 73,750,466 (-)	NCBI		T2T-CHM13v2.0

Tprkb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	85,888,842 - 85,907,266 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	85,888,847 - 85,907,266 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	85,911,860 - 85,930,284 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	85,911,865 - 85,930,284 (+)	Ensembl			mm10	GRCm38
MGSCv37	6	85,865,713 - 85,880,278 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	85,881,391 - 85,895,916 (+)	NCBI		MGSCv36	mm8
Celera	6	87,850,066 - 87,864,628 (+)	NCBI		Celera
Cytogenetic Map	6	C3	NCBI
cM Map	6	37.53	NCBI

Tprkb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	11,961,994 - 11,969,610 (-)	Ensembl
ChiLan1.0	NW_004955424	11,961,994 - 11,969,610 (-)	NCBI	ChiLan1.0	ChiLan1.0

TPRKB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	52,628,617 - 52,642,027 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	52,634,551 - 52,644,779 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	73,791,353 - 73,801,570 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	75,326,512 - 75,334,293 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	75,326,512 - 75,334,271 (-)	Ensembl			panPan2	panpan1.1

TPRKB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	49,271,845 - 49,278,794 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	49,245,496 - 49,278,767 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	48,915,787 - 48,922,753 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	50,134,238 - 50,141,211 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	50,134,333 - 50,141,159 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	49,150,408 - 49,157,381 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	49,217,775 - 49,224,740 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	49,776,764 - 49,783,740 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tprkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	11,070,697 - 11,077,667 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936491	17,493,285 - 17,500,523 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936491	17,493,630 - 17,500,779 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TPRKB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	69,236,351 - 69,243,914 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	69,235,111 - 69,243,709 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	72,437,613 - 72,445,206 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TPRKB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	33,518,089 - 33,526,122 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	33,521,398 - 33,527,613 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	78,574,105 - 78,585,601 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tprkb
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	60,392,938 - 60,406,817 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tprkb
47 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	242
Count of miRNA genes:	137
Interacting mature miRNAs:	143
Transcripts:	ENSRNOT00000021211, ENSRNOT00000074924
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631689	Scl4	Serum cholesterol level QTL 4	1.9	0.008	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	4	96731383	141731383	Rat
1582232	Gluco25	Glucose level QTL 25	3.6	0.0023	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	86583980	149763391	Rat
2302049	Pia32	Pristane induced arthritis QTL 32	5.1	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)	4	107346299	152346299	Rat
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	39431983	123203361	Rat
1578655	Bmd11	Bone mineral density QTL 11	11		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	4	92406430	137406430	Rat
1300116	Hrtrt5	Heart rate QTL 5	3.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	117737142	152833657	Rat
6478763	Anxrr46	Anxiety related response QTL 46		0.07428	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	112427331	157427331	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
6478760	Anxrr45	Anxiety related response QTL 45		0.06717	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	112427331	157427331	Rat
1331802	Srn5	Serum renin concentration QTL 5	3.045		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	4	117559384	162559384	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
2306545	Iddm39	Insulin dependent diabetes mellitus QTL 39			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	78687630	123687630	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	26234499	134199155	Rat
7207480	Bss105	Bone structure and strength QTL 105	8.1		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	4	111383604	156383604	Rat
731165	Uae21	Urinary albumin excretion QTL 21	2.4	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	4	108206096	153206096	Rat
737821	Hcar9	Hepatocarcinoma resistance QTL 9	3.7		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	106848959	168870974	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	94638356	168870820	Rat
631646	Stl4	Serum triglyceride level QTL 4	6.5	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	4	74169813	134199155	Rat
634334	Xhs3	X-ray hypersensitivity QTL 3	10		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	86058928	131411333	Rat
61406	Scwia1	Streptococcal cell wall induced arthritis QTL 1	2.3		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	4	75939858	140508796	Rat
1549832	Bss3	Bone structure and strength QTL 3	11		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	4	111383604	156383604	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	82944895	154403548	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	45429897	149763204	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	27862204	126119996	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5889999	148002343	Rat
61476	Aia3	Adjuvant induced arthritis QTL 3	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	75939858	140508796	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	174095838	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	100752691	179366077	Rat
1641919	Alc22	Alcohol consumption QTL 22		0.0005	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	65060960	127749483	Rat
631662	Hcar2	Hepatocarcinoma resistance QTL 2	3.1	0.0003	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	84349032	129349032	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	45429709	157555683	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	63245026	129846354	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	0.02	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	86709649	168870974	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	57664252	127749483	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	45429897	149763204	Rat
2306899	Bp338	Blood pressure QTL 338		0.071	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	82336765	127336765	Rat
2293840	Kiddil9	Kidney dilation QTL 9	2.9		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	4	113634167	149763391	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	65495851	159259805	Rat
12798519	Anxrr54	Anxiety related response QTL 54	2.54	0.05	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	116184844	161184844	Rat
1578670	Bss14	Bone structure and strength QTL 14	16.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	4	88883695	133883695	Rat
70201	Gcr1	Gastric cancer resistance QTL 1	2.7		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	4	103834277	148834277	Rat
12798523	Anxrr56	Anxiety related response QTL 56	2.83	0.05	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	86583980	131583980	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	57613339	151163960	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
1578662	Bss15	Bone structure and strength QTL 15	19.6		femur width (VT:1000666)	femoral neck width (CMO:0001695)	4	88883695	133883695	Rat

Markers in Region

RH131550

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	118,341,589 - 118,341,798 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	117,771,144 - 117,771,352	NCBI	Rnor6.0
Rnor_6.0	4	117,588,161 - 117,588,369	NCBI	Rnor6.0
Rnor_5.0	4	182,343,669 - 182,343,877	UniSTS	Rnor5.0
Rnor_5.0	4	182,162,675 - 182,162,883	UniSTS	Rnor5.0
RGSC_v3.4	4	120,064,693 - 120,064,901	UniSTS	RGSC3.4
Celera	4	107,314,949 - 107,315,157	UniSTS
RH 3.4 Map	4	694.3	UniSTS
Cytogenetic Map	4	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	12	61	134	57	60	41	87	41	299	169	11	125	71	73	19	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003749789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236746	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039107356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039107357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039107359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039107360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC095078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473957	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK475733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV112449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234910	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021211 ⟹ ENSRNOP00000021211

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	119,904,605 - 119,915,382 (+)	Ensembl
mRatBN7.2 Ensembl	4	118,343,010 - 118,357,901 (+)	Ensembl
Rnor_6.0 Ensembl	4	117,780,533 - 117,785,941 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000074924 ⟹ ENSRNOP00000066993

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	119,905,605 - 119,915,382 (+)	Ensembl
mRatBN7.2 Ensembl	4	118,342,945 - 118,354,005 (+)	Ensembl
Rnor_6.0 Ensembl	4	117,594,805 - 117,603,155 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078239 ⟹ ENSRNOP00000074558

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	119,900,484 - 119,913,780 (+)	Ensembl
mRatBN7.2 Ensembl	4	118,343,020 - 118,356,316 (+)	Ensembl
Rnor_6.0 Ensembl	4	117,589,591 - 117,602,887 (+)	Ensembl

RefSeq Acc Id:

NM_001013926 ⟹ NP_001013948

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,900,499 - 119,913,984 (+)	NCBI
mRatBN7.2	4	118,343,035 - 118,356,520 (+)	NCBI
Rnor_6.0	4	117,589,606 - 117,603,091 (+)	NCBI
Rnor_5.0	4	182,345,035 - 182,359,990 (+)	NCBI
RGSC_v3.4	4	120,066,138 - 120,079,624 (+)	RGD
Celera	4	107,316,394 - 107,329,878 (+)	RGD

Sequence:

show sequence

GAGACTGAGGGCATTTTCCAGACTGTAAAGACCCACGCTCCTAATCTCCTCTAATCTTGAACTT
CTGATCCTCCTCTTCTGACCTTCACTGGATTCTAGAGAGACCTCCTTGTCTATGAAATGCAGTT
AACACAGCAGCTGGACTTGTTTCCCGAGTGCAAGGTGACCCTTCTGTTATTTAAAGATGTAAAA
AATGCAGGAGACTTGAGAAAAAAGGCCATGGAAGGATCTATAGATGGCTCATTGATAAATGCCA
ATGTGATTGTCGATCCATTTCAAATACTTGTGGCAGCAAACAAAGCCGTTCATCTCCACAAACT
GGGAAAAATGAAGACAAGAACTCTGTCTACTGAAATTATCTTCAACCTCTCCCCAAATAATAAT
ATTTCAGAGGCTTTGAAGAAGTTTGGCATCTCAGAAAGTAACACTTCAGTTCTGATTGTTTATG
TTGAAGATGGAGACAAACAAGTGCATCAGGAACACCTAGTATCTCAAGTGGAAGGCCAGCAGGT
GCCCTTGGAAAGTCTTCCTGAAATAACAAGGCTCTCAGAAGTCAGGAAGATATATAAACTGTCA
TCACAAGAAGAGAGGATTGGGACATTATTGGATGGTATCATTTGTAGAATGTCAACAAAGGATG
TTTTATAAGTTGTTTAAAATATCAACAGAAAATCATAGAGGTAATTACTAGCTTTTCTTTCCCA
CTTCTAAATTAACATTCTCATCACAGGAAAAGGGAAGAAGTACTACTACCAGTCCCGTTGTTTT
TTACTTTCTAAG

hide sequence

RefSeq Acc Id:

XM_006236743 ⟹ XP_006236805

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,900,411 - 119,915,374 (+)	NCBI
mRatBN7.2	4	118,342,947 - 118,356,890 (+)	NCBI

Sequence:

show sequence

CAAACATTAAGCTCTTCCGGAAGTAGAGAGCTTCGTTTCCAAGGGGACGATCTTCTGAGACGGA
CAGGAGACTGAGGGAACAGGCTATCTCTTGGAGTCTGAAGAAGATAGCCAGTCCCACCATGACA
AGATTCCAGCCACAGTGGAAGATGAAAAGACCTTCCTTCAGCTACGTCCCCTGGTTCTAGAGGA
GTCTCCTGTGTATACACGTTTGTGGCATCTGAGCCGTAGAAGCATTTTCCAGACTGTAAAGACC
CACGCTCCTAATCTCCTCTAATCTTGAACTTCTGATCCTCCTCTTCTGACCTTCACTGGATTCT
AGAGAGACCTCCTTGTCTATGAAATGCAGTTAACACAGCAGCTGGACTTGTTTCCCGAGTGCAA
GGTGACCCTTCTGTTATTTAAAGATGTAAAAAATGCAGGAGACTTGAGAAAAAAGGCCATGGAA
GGATCTATAGATGGCTCATTGATAAATGCCAATGTGATTGTCGATCCATTTCAAATACTTGTGG
CAGCAAACAAAGCCGTTCATCTCCACAAACTGGGAAAAATGAAGACAAGAACTCTGTCTACTGA
AATTATCTTCAACCTCTCCCCAAATAATAATATTTCAGAGGCTTTGAAGAAGTTTGGCATCTCA
GAAAGTAACACTTCAGTTCTGATTGTTTATGTTGAAGATGGAGACAAACAAGTGCATCAGGAAC
ACCTAGTATCTCAAGTGGAAGGCCAGCAGGTGCCCTTGGAAAGTCTTCCTGAAATAACAAGGCT
CTCAGAAGTCAGGAAGATATATAAACTGTCATCACAAGAAGAGAGGATTGGGACATTATTGGAT
GGTATCATTTGTAGAATGTCAACAAAGGATGTTTTATAAGTTGTTTAAAATATCAACAGAAAAT
CATAGAGGTAATTACTAGCTTTTCTTTCCCACTTCTAAAATTAACATTCTCATCACAGGAAAAG
GGAAGAAGGTACTACTACCAGTCCGTTTGTTTTTTTACTTCTTAAAGATAACCTCTGTCACTGG
TTTTATCATTGTTATTTAGTCCTCTACTTATATTTCAAGACCTTTCATTTTTATACAATTGGAA
TAAAAAGTGCAAGCACCTAGAGAAGGCTTCGGTGCTCAAGGCTCAGCCTCAGTAATCCTTCATC
ACTTTGTCACTCACCTTATACTTCTGGCTTTTCCACATTGCCCTTCTAAGCTCTGGGTCCTGAG
AGTTTTACGCCTAAGAATTTCTTTTACTCTAAGCCAGGTGTGGTGACTTTTTACAGTCCACTAC
TCAGGAGGCTGAGGCAGGAGAAAGCTACAAGTTCAAGATCAGCCTAAAGTACTATGTCAGTTCC
CTTCTCAATAAATACACAGCAGTTCATTTAACTCTCTTAGCCACTTATTAAGTGGATATGTCTT
TGTGCCTCTTTATACACGAGGCAACTGAAAGATTGTAGGAATACTAACCGATTAGCCTAGGGTC
ATGTAACTAGTATAAAACCATGTTTGACGGTTCCTTTTCCCCCTCACTTTATCTTGTATTTTGA
TTGTATCCATCACAATAGGTTTGGTCAAAGGTCAGCAAAACATTGCTCCTCAAAGGCCATCTGG
TCCCTGCTCAATTACTCAATACCACCTTTGCAGTCTGAAAGCAGATACAGAGGACAGGTGGATA
GTGAGTGGCCTCTGTCCGTAAGCATTGAGTTGAGCTGGCGGTGGGCAGCCCTGGAGTTGAGGCT
GTGGACTCCAGAGTTGGTTATAGTGACAGTCAGGCCTTAAAGCTCACTGGCTCAGTACAGCAGA
AGGAAACATTTCGTTATCTTTAAGGTCATACAGACCATAGGGAAAACCGGCAGCTGTGTTTTAG
GAGCCTTCTGCTGGGCCTCTCACCCTGGGCTTTTAGGTTACCGTGCAGCTGGGCAGAAGCTCTG
GGGAGGCAGTGTACCTTGAAAGCATCCACACGGGAGAGACCATATTGCTCACCTCTTTTCTTTC
ATACAAGTTTTAAAATGGTGACTCCATGTTCTTCCCCCAAGCCCAGTCAGTTCTGCGCCTTCAG
TCCTCTCTAGAGCTCCTAGTCTGAAAAGCCTGGAACCCTCTCAGAGTGCAGTTCTAGGGTTGTT
CTCTAGGTACCCTGTGGTGGTTTGAATACACCTGGCCTAGGGAGTGGCACTATTAGGAGGTGTG
GCCTTGTTGGAGTAGGTATGGCCTTGACAGAGTTGGAGTAGTATGTCACTGTGGGCATGGGCTT
GGGAGCCAGTCTTTTCTTGGTGGCCTTCAGATGAAGATGTAGAGCTCTCAGCTCCTGCACCATG
CCTGCCTAGACACTGTCATGCTCCTGCCTTGATGATAATGGACTGAAACTCTGAACCTGTAAGC
CAGCCCCAATTAAATGTCCTTATAAGA

hide sequence

RefSeq Acc Id:

XM_006236746 ⟹ XP_006236808

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,900,383 - 119,915,374 (+)	NCBI
mRatBN7.2	4	118,342,919 - 118,356,890 (+)	NCBI

Sequence:

show sequence

GTCCACCTGATCAAACATTAAGCTCTTCCGGAAGTAGAGAGCTTCGTTTCCAAGGGGACGATCT
TCTGAGACGGACAGGAGACTGAGGAGAGACCTCCTTGTCTATGAAATGCAGTTAACACAGCAGC
TGGACTTGTTTCCCGAGTGCAAGGTGACCCTTCTGTTATTTAAAGATGTAAAAAATGCAGGAGA
CTTGAGAAAAAAGGCCATGGAAGGATCTATAGATGGCTCATTGATAAATGCCAATGTGATTGTC
GATCCATTTCAAATACTTGTGGCAGCAAACAAAGCCGTTCATCTCCACAAACTGGGAAAAATGA
AGACAAGAACTCTGTCTACTGAAATTATCTTCAACCTCTCCCCAAATAATAATATTTCAGAGGC
TTTGAAGAAGTTTGGCATCTCAGAAAGTAACACTTCAGTTCTGATTGTTTATGTTGAAGATGGA
GACAAACAAGTGCATCAGGAACACCTAGTATCTCAAGTGGAAGGCCAGCAGGTGCCCTTGGAAA
GTCTTCCTGAAATAACAAGGCTCTCAGAAGTCAGGAAGATATATAAACTGTCATCACAAGAAGA
GAGGATTGGGACATTATTGGATGGTATCATTTGTAGAATGTCAACAAAGGATGTTTTATAAGTT
GTTTAAAATATCAACAGAAAATCATAGAGGTAATTACTAGCTTTTCTTTCCCACTTCTAAAATT
AACATTCTCATCACAGGAAAAGGGAAGAAGGTACTACTACCAGTCCGTTTGTTTTTTTACTTCT
TAAAGATAACCTCTGTCACTGGTTTTATCATTGTTATTTAGTCCTCTACTTATATTTCAAGACC
TTTCATTTTTATACAATTGGAATAAAAAGTGCAAGCACCTAGAGAAGGCTTCGGTGCTCAAGGC
TCAGCCTCAGTAATCCTTCATCACTTTGTCACTCACCTTATACTTCTGGCTTTTCCACATTGCC
CTTCTAAGCTCTGGGTCCTGAGAGTTTTACGCCTAAGAATTTCTTTTACTCTAAGCCAGGTGTG
GTGACTTTTTACAGTCCACTACTCAGGAGGCTGAGGCAGGAGAAAGCTACAAGTTCAAGATCAG
CCTAAAGTACTATGTCAGTTCCCTTCTCAATAAATACACAGCAGTTCATTTAACTCTCTTAGCC
ACTTATTAAGTGGATATGTCTTTGTGCCTCTTTATACACGAGGCAACTGAAAGATTGTAGGAAT
ACTAACCGATTAGCCTAGGGTCATGTAACTAGTATAAAACCATGTTTGACGGTTCCTTTTCCCC
CTCACTTTATCTTGTATTTTGATTGTATCCATCACAATAGGTTTGGTCAAAGGTCAGCAAAACA
TTGCTCCTCAAAGGCCATCTGGTCCCTGCTCAATTACTCAATACCACCTTTGCAGTCTGAAAGC
AGATACAGAGGACAGGTGGATAGTGAGTGGCCTCTGTCCGTAAGCATTGAGTTGAGCTGGCGGT
GGGCAGCCCTGGAGTTGAGGCTGTGGACTCCAGAGTTGGTTATAGTGACAGTCAGGCCTTAAAG
CTCACTGGCTCAGTACAGCAGAAGGAAACATTTCGTTATCTTTAAGGTCATACAGACCATAGGG
AAAACCGGCAGCTGTGTTTTAGGAGCCTTCTGCTGGGCCTCTCACCCTGGGCTTTTAGGTTACC
GTGCAGCTGGGCAGAAGCTCTGGGGAGGCAGTGTACCTTGAAAGCATCCACACGGGAGAGACCA
TATTGCTCACCTCTTTTCTTTCATACAAGTTTTAAAATGGTGACTCCATGTTCTTCCCCCAAGC
CCAGTCAGTTCTGCGCCTTCAGTCCTCTCTAGAGCTCCTAGTCTGAAAAGCCTGGAACCCTCTC
AGAGTGCAGTTCTAGGGTTGTTCTCTAGGTACCCTGTGGTGGTTTGAATACACCTGGCCTAGGG
AGTGGCACTATTAGGAGGTGTGGCCTTGTTGGAGTAGGTATGGCCTTGACAGAGTTGGAGTAGT
ATGTCACTGTGGGCATGGGCTTGGGAGCCAGTCTTTTCTTGGTGGCCTTCAGATGAAGATGTAG
AGCTCTCAGCTCCTGCACCATGCCTGCCTAGACACTGTCATGCTCCTGCCTTGATGATAATGGA
CTGAAACTCTGAACCTGTAAGCCAGCCCCAATTAAATGTCCTTATAAGA

hide sequence

RefSeq Acc Id:

XM_017593013 ⟹ XP_017448502

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,900,397 - 119,915,374 (+)	NCBI
mRatBN7.2	4	118,343,025 - 118,357,908 (+)	NCBI

Sequence:

show sequence

GTAGAGAGCTTCGTTTCCAAGGGGACGATCTTCTGAGACGGACAGGAGACTGAGGACCTCCTTG
TCTATGAAATGCAGTTAACACAGCAGCTGGACTTGTTTCCCGAGTGCAAGGTGACCCTTCTGTT
ATTTAAAGATGTAAAAAATGCAGGAGACTTGAGAAAAAAGGCCATGGAAGGATCTATAGATGGC
TCATTGATAAATGCCAATGTGATTGTCGATCCATTTCAAATACTTGTGGCAGCAAACAAAGCCG
TTCATCTCCACAAACTGGGAAAAATGAAGACAAGAACTCTGTCTACTGAAATTATCTTCAACCT
CTCCCCAAATAATAATATTTCAGAGGCTTTGAAGAAGTTTGGCATCTCAGAAAGTAACACTTCA
GTTCTGATTGTTTATGTTGAAGATGGAGACAAACAAGTGCATCAGGAACACCTAGTATCTCAAG
TGGAAGGCCAGCAGGTGCCCTTGGAAAGTCTTCCTGAAATAACAAGGCTCTCAGAAGTCAGGAA
GATATATAAACTGTCATCACAAGAAGAGAGGATTGGGACATTATTGGATGGTATCATTTGTAGA
ATGTCAACAAAGGATGTTTTATAAGTTGTTTAAAATATCAACAGAAAATCATAGAGGTAATTAC
TAGCTTTTCTTTCCCACTTCTAAAATTAACATTCTCATCACAGGAAAAGGGAAGAAGGTACTAC
TACCAGTCCGTTTGTTTTTTTACTTCTTAAAGATAACCTCTGTCACTGGTTTTATCATTGTTAT
TTAGTCCTCTACTTATATTTCAAGACCTTTCATTTTTATACAATTGGAATAAAAAGTGCAAGCA
CCTAGAGAAGGCTTCGGTGCTCAAGGCTCAGCCTCAGTAATCCTTCATCACTTTGTCACTCACC
TTATACTTCTGGCTTTTCCACATTGCCCTTCTAAGCTCTGGGTCCTGAGAGTTTTACGCCTAAG
AATTTCTTTTACTCTAAGCCAGGTGTGGTGACTTTTTACAGTCCACTACTCAGGAGGCTGAGGC
AGGAGAAAGCTACAAGTTCAAGATCAGCCTAAAGTACTATGTCAGTTCCCTTCTCAATAAATAC
ACAGCAGTTCATTTAACTCTCTTAGCCACTTATTAAGTGGATATGTCTTTGTGCCTCTTTATAC
ACGAGGCAACTGAAAGATTGTAGGAATACTAACCGATTAGCCTAGGGTCATGTAACTAGTATAA
AACCATGTTTGACGGTTCCTTTTCCCCCTCACTTTATCTTGTATTTTGATTGTATCCATCACAA
TAGGTTTGGTCAAAGGTCAGCAAAACATTGCTCCTCAAAGGCCATCTGGTCCCTGCTCAATTAC
TCAATACCACCTTTGCAGTCTGAAAGCAGATACAGAGGACAGGTGGATAGTGAGTGGCCTCTGT
CCGTAAGCATTGAGTTGAGCTGGCGGTGGGCAGCCCTGGAGTTGAGGCTGTGGACTCCAGAGTT
GGTTATAGTGACAGTCAGGCCTTAAAGCTCACTGGCTCAGTACAGCAGAAGGAAACATTTCGTT
ATCTTTAAGGTCATACAGACCATAGGGAAAACCGGCAGCTGTGTTTTAGGAGCCTTCTGCTGGG
CCTCTCACCCTGGGCTTTTAGGTTACCGTGCAGCTGGGCAGAAGCTCTGGGGAGGCAGTGTACC
TTGAAAGCATCCACACGGGAGAGACCATATTGCTCACCTCTTTTCTTTCATACAAGTTTTAAAA
TGGTGACTCCATGTTCTTCCCCCAAGCCCAGTCAGTTCTGCGCCTTCAGTCCTCTCTAGAGCTC
CTAGTCTGAAAAGCCTGGAACCCTCTCAGAGTGCAGTTCTAGGGTTGTTCTCTAGGTACCCTGT
GGTGGTTTGAATACACCTGGCCTAGGGAGTGGCACTATTAGGAGGTGTGGCCTTGTTGGAGTAG
GTATGGCCTTGACAGAGTTGGAGTAGTATGTCACTGTGGGCATGGGCTTGGGAGCCAGTCTTTT
CTTGGTGGCCTTCAGATGAAGATGTAGAGCTCTCAGCTCCTGCACCATGCCTGCCTAGACACTG
TCATGCTCCTGCCTTGATGATAATGGACTGAAACTCTGAACCTGTAAGCCAGCCCCAATTAAAT
GTCCTTATAAGA

hide sequence

RefSeq Acc Id:

XM_039107356 ⟹ XP_038963284

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,903,256 - 119,915,374 (+)	NCBI
mRatBN7.2	4	118,345,736 - 118,357,908 (+)	NCBI

RefSeq Acc Id:

XM_039107357 ⟹ XP_038963285

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,903,256 - 119,915,374 (+)	NCBI
mRatBN7.2	4	118,345,735 - 118,357,908 (+)	NCBI

RefSeq Acc Id:

XM_039107359 ⟹ XP_038963287

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,904,772 - 119,915,374 (+)	NCBI
mRatBN7.2	4	118,342,995 - 118,357,908 (+)	NCBI

RefSeq Acc Id:

XM_039107360 ⟹ XP_038963288

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,900,374 - 119,915,374 (+)	NCBI
mRatBN7.2	4	118,342,910 - 118,356,890 (+)	NCBI

RefSeq Acc Id:

XM_063285808 ⟹ XP_063141878

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,900,391 - 119,915,374 (+)	NCBI

RefSeq Acc Id:

XM_063285809 ⟹ XP_063141879

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,900,392 - 119,915,374 (+)	NCBI

RefSeq Acc Id:

XM_063285810 ⟹ XP_063141880

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	119,900,391 - 119,915,374 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013948	(Get FASTA)	NCBI Sequence Viewer
	XP_006236805	(Get FASTA)	NCBI Sequence Viewer
	XP_006236808	(Get FASTA)	NCBI Sequence Viewer
	XP_017448502	(Get FASTA)	NCBI Sequence Viewer
	XP_038963284	(Get FASTA)	NCBI Sequence Viewer
	XP_038963285	(Get FASTA)	NCBI Sequence Viewer
	XP_038963287	(Get FASTA)	NCBI Sequence Viewer
	XP_038963288	(Get FASTA)	NCBI Sequence Viewer
	XP_063141878	(Get FASTA)	NCBI Sequence Viewer
	XP_063141879	(Get FASTA)	NCBI Sequence Viewer
	XP_063141880	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH87060	(Get FASTA)	NCBI Sequence Viewer
	EDL91207	(Get FASTA)	NCBI Sequence Viewer
	EDL91208	(Get FASTA)	NCBI Sequence Viewer
	EDL91209	(Get FASTA)	NCBI Sequence Viewer
	EDL91210	(Get FASTA)	NCBI Sequence Viewer
	EDL91211	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021211
	ENSRNOP00000066993
	ENSRNOP00000074558.1
GenBank Protein	Q5PQR8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001013948 ⟸ NM_001013926
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), G3V805 (UniProtKB/TrEMBL), A6IAU0 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHL HKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEG QQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL hide sequence

RefSeq Acc Id:	XP_038963288 ⟸ XM_039107360
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), G3V805 (UniProtKB/TrEMBL), A6IAU0 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_006236808 ⟸ XM_006236746
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), G3V805 (UniProtKB/TrEMBL), A6IAU0 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHL HKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEG QQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL hide sequence

RefSeq Acc Id:	XP_006236805 ⟸ XM_006236743
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), G3V805 (UniProtKB/TrEMBL), A6IAU0 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHL HKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEG QQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL hide sequence

RefSeq Acc Id:	XP_038963287 ⟸ XM_039107359
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), G3V805 (UniProtKB/TrEMBL), A6IAU0 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_017448502 ⟸ XM_017593013
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), G3V805 (UniProtKB/TrEMBL), A6IAU0 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHL HKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEG QQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL hide sequence

RefSeq Acc Id:	XP_038963285 ⟸ XM_039107357
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), G3V805 (UniProtKB/TrEMBL), A6IAU0 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038963284 ⟸ XM_039107356
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), G3V805 (UniProtKB/TrEMBL), A6IAU0 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000021211 ⟸ ENSRNOT00000021211

Ensembl Acc Id:

ENSRNOP00000066993 ⟸ ENSRNOT00000074924

Ensembl Acc Id:

ENSRNOP00000074558 ⟸ ENSRNOT00000078239

RefSeq Acc Id:	XP_063141878 ⟸ XM_063285808
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), A6IAU0 (UniProtKB/TrEMBL), G3V805 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063141880 ⟸ XM_063285810
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), A6IAU0 (UniProtKB/TrEMBL), G3V805 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063141879 ⟸ XM_063285809
- Peptide Label:	isoform X1
- UniProtKB:	Q5PQR8 (UniProtKB/Swiss-Prot), A6IAU0 (UniProtKB/TrEMBL), G3V805 (UniProtKB/TrEMBL), A6IAU1 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5PQR8-F1-model_v2	AlphaFold	Q5PQR8	1-158	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309786	AgrOrtholog
BioCyc Gene	G2FUF-43923	BioCyc
Ensembl Genes	ENSRNOG00000015818	Ensembl
	ENSRNOG00000050645	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000021211	ENTREZGENE
	ENSRNOT00000074924	ENTREZGENE
	ENSRNOT00000078239.2	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.2380.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7125830	IMAGE-MGC_LOAD
InterPro	CGI121/TPRKB	UniProtKB/Swiss-Prot
	CGI121/TPRKB_sf	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94108	IMAGE-MGC_LOAD
NCBI Gene	297411	ENTREZGENE
PANTHER	EKC/KEOPS COMPLEX SUBUNIT TPRKB	UniProtKB/Swiss-Prot
	PTHR15840	UniProtKB/Swiss-Prot
Pfam	CGI-121	UniProtKB/Swiss-Prot
PhenoGen	Tprkb	PhenoGen
RatGTEx	ENSRNOG00000015818	RatGTEx
	ENSRNOG00000050645	RatGTEx
Superfamily-SCOP	SSF143870	UniProtKB/Swiss-Prot
UniProt	A6IAU0	ENTREZGENE, UniProtKB/TrEMBL
	A6IAU1	ENTREZGENE, UniProtKB/TrEMBL
	A6IAU3_RAT	UniProtKB/TrEMBL
	G3V805	ENTREZGENE, UniProtKB/TrEMBL
	M0RBP8_RAT	UniProtKB/TrEMBL
	Q5PQR8	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Tprkb	Tp53rk binding protein	LOC103690067	EKC/KEOPS complex subunit Tprkb	Data merged from RGD:9395731	737654	PROVISIONAL
2015-07-29	Tprkb	Tp53rk binding protein	LOC100910911	TP53RK-binding protein-like	Data merged from RGD:6495877	737654	PROVISIONAL
2014-08-25	LOC103690067	EKC/KEOPS complex subunit Tprkb			Symbol and Name status set to provisional	70820	PROVISIONAL
2012-07-05	LOC100910911	TP53RK-binding protein-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-30	Tprkb	Tp53rk binding protein	RGD1309786	similar to CGI-121 protein	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1309786	similar to CGI-121 protein	RGD1309786_predicted	similar to CGI-121 protein (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1309786_predicted	similar to CGI-121 protein (predicted)	LOC297411_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC297411_predicted	similar to CGI-121 protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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