Hectd4 (HECT domain E3 ubiquitin protein ligase 4) - Rat Genome Database

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Pathways
Gene: Hectd4 (HECT domain E3 ubiquitin protein ligase 4) Rattus norvegicus
Analyze
Symbol: Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
RGD ID: 1309762
Description: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in glucose homeostasis and glucose metabolic process. Orthologous to human HECTD4 (HECT domain E3 ubiquitin protein ligase 4); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: HECT domain containing E3 ubiquitin protein ligase 4; LOC304503; probable E3 ubiquitin-protein ligase HECTD4; RGD1309762; similar to KIAA0614 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81240,800,232 - 40,991,584 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1240,843,770 - 40,991,798 (-)EnsemblGRCr8
mRatBN7.21235,182,165 - 35,330,935 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1235,182,154 - 35,330,987 (-)EnsemblmRatBN7.2
Rnor_6.01240,712,078 - 40,860,930 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,713,841 - 40,822,159 (-)Ensemblrn6Rnor6.0
Rnor_5.01242,579,193 - 42,728,149 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41236,318,373 - 36,423,169 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1236,847,681 - 36,995,299 (-)NCBICelera
RGSC_v3.11236,183,146 - 36,299,948 (-)NCBI
Cytogenetic Map12q16NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:23575436   PMID:36527595  


Genomics

Comparative Map Data
Hectd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81240,800,232 - 40,991,584 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1240,843,770 - 40,991,798 (-)EnsemblGRCr8
mRatBN7.21235,182,165 - 35,330,935 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1235,182,154 - 35,330,987 (-)EnsemblmRatBN7.2
Rnor_6.01240,712,078 - 40,860,930 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,713,841 - 40,822,159 (-)Ensemblrn6Rnor6.0
Rnor_5.01242,579,193 - 42,728,149 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41236,318,373 - 36,423,169 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1236,847,681 - 36,995,299 (-)NCBICelera
RGSC_v3.11236,183,146 - 36,299,948 (-)NCBI
Cytogenetic Map12q16NCBI
HECTD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812112,160,195 - 112,382,431 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12112,160,188 - 112,382,439 (-)Ensemblhg38GRCh38
GRCh3712112,597,999 - 112,820,235 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612111,082,494 - 111,228,421 (-)NCBIBuild 36Build 36hg18NCBI36
Celera12112,223,478 - 112,446,926 (-)NCBICelera
Cytogenetic Map12q24.13NCBI
HuRef12109,611,135 - 109,832,758 (-)NCBIHuRef
CHM1_112112,566,184 - 112,788,132 (-)NCBICHM1_1
T2T-CHM13v2.012112,137,101 - 112,359,329 (-)NCBIT2T-CHM13v2.0
Hectd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395121,357,323 - 121,506,633 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5121,358,282 - 121,506,640 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385121,219,513 - 121,368,577 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5121,220,219 - 121,368,577 (+)Ensemblmm10GRCm38
MGSCv375121,670,214 - 121,818,586 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365121,585,831 - 121,629,192 (+)NCBIMGSCv36mm8
Celera5118,310,100 - 118,458,521 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map561.72NCBI
Hectd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554828,716,092 - 8,847,979 (-)Ensembl
ChiLan1.0NW_0049554828,714,100 - 8,847,975 (-)NCBIChiLan1.0ChiLan1.0
HECTD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210120,250,769 - 120,472,956 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112120,247,162 - 120,469,341 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012109,756,303 - 109,978,510 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112113,150,901 - 113,309,528 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12113,151,017 - 113,311,809 (-)EnsemblpanPan2panpan1.1
HECTD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1269,764,437 - 9,954,274 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl269,767,169 - 9,954,118 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha269,883,238 - 10,071,992 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02610,002,501 - 10,193,532 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2610,003,319 - 10,193,589 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1269,979,339 - 10,168,130 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02610,042,607 - 10,231,400 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02610,090,235 - 10,279,116 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hectd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118147,892,128 - 148,068,653 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366682,390,405 - 2,514,708 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366682,390,902 - 2,514,653 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HECTD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1439,326,792 - 39,536,693 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11439,326,695 - 39,537,921 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21441,829,770 - 42,040,718 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HECTD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111107,403,854 - 107,624,534 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11107,405,887 - 107,596,312 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037137,465,425 - 137,688,609 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hectd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474719,843,720 - 20,029,225 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474719,843,434 - 20,031,188 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Hectd4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11632,449,404 - 32,600,070 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hectd4
1256 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:96
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000001826
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122977552242298555Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)123424347543352593Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat

Markers in Region
D12Rat52  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81240,972,969 - 40,973,114 (+)Marker Load Pipeline
mRatBN7.21235,312,313 - 35,312,458 (+)MAPPERmRatBN7.2
Rnor_6.01240,842,405 - 40,842,549NCBIRnor6.0
Rnor_5.01242,709,520 - 42,709,664UniSTSRnor5.0
RGSC_v3.41236,448,697 - 36,448,841RGDRGSC3.4
RGSC_v3.41236,448,698 - 36,448,842UniSTSRGSC3.4
Celera1236,976,786 - 36,976,930UniSTS
RGSC_v3.11236,312,085 - 36,312,229RGD
RH 3.4 Map12613.1UniSTS
RH 3.4 Map12613.1RGD
RH 2.0 Map12529.4RGD
SHRSP x BN Map1244.35RGD
Cytogenetic Map12q16UniSTS
D12Got80  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,288,242 - 35,288,330 (+)MAPPERmRatBN7.2
Rnor_6.01240,818,303 - 40,818,390NCBIRnor6.0
Rnor_5.01242,685,418 - 42,685,505UniSTSRnor5.0
RGSC_v3.41236,424,627 - 36,424,714RGDRGSC3.4
RGSC_v3.41236,424,628 - 36,424,715UniSTSRGSC3.4
Celera1236,952,826 - 36,952,913UniSTS
RGSC_v3.11236,288,015 - 36,288,102RGD
RH 3.4 Map12610.7UniSTS
RH 3.4 Map12610.7RGD
Cytogenetic Map12q16UniSTS
D12Got214  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,225,205 - 35,225,385 (+)MAPPERmRatBN7.2
Rnor_6.01240,755,113 - 40,755,290NCBIRnor6.0
Rnor_5.01242,622,228 - 42,622,405UniSTSRnor5.0
RGSC_v3.41236,361,416 - 36,361,593UniSTSRGSC3.4
Celera1236,890,707 - 36,890,884UniSTS
Cytogenetic Map12q16UniSTS
RH144598  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,218,576 - 35,218,726 (+)MAPPERmRatBN7.2
Rnor_6.01240,748,486 - 40,748,635NCBIRnor6.0
Rnor_5.01242,615,601 - 42,615,750UniSTSRnor5.0
RGSC_v3.41236,354,789 - 36,354,938UniSTSRGSC3.4
Celera1236,884,080 - 36,884,229UniSTS
RH 3.4 Map12616.8UniSTS
Cytogenetic Map12q16UniSTS
AW533080  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,258,451 - 35,258,631 (+)MAPPERmRatBN7.2
Rnor_6.01240,788,457 - 40,788,636NCBIRnor6.0
Rnor_5.01242,655,572 - 42,655,751UniSTSRnor5.0
RGSC_v3.41236,394,782 - 36,394,961UniSTSRGSC3.4
Celera1236,923,865 - 36,924,044UniSTS
RH 3.4 Map12609.7UniSTS
Cytogenetic Map12q16UniSTS
BI294823  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,279,985 - 35,280,174 (+)MAPPERmRatBN7.2
Rnor_6.01240,810,046 - 40,810,234NCBIRnor6.0
Rnor_5.01242,677,161 - 42,677,349UniSTSRnor5.0
RGSC_v3.41236,416,371 - 36,416,559UniSTSRGSC3.4
Celera1236,944,569 - 36,944,757UniSTS
RH 3.4 Map12615.0UniSTS
Cytogenetic Map12q16UniSTS
BF388170  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,223,224 - 35,223,407 (+)MAPPERmRatBN7.2
Rnor_6.01240,753,132 - 40,753,314NCBIRnor6.0
Rnor_5.01242,620,247 - 42,620,429UniSTSRnor5.0
RGSC_v3.41236,359,435 - 36,359,617UniSTSRGSC3.4
Celera1236,888,726 - 36,888,908UniSTS
RH 3.4 Map12614.4UniSTS
Cytogenetic Map12q16UniSTS
UniSTS:532167  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,249,890 - 35,250,836 (+)MAPPERmRatBN7.2
Rnor_6.01240,779,896 - 40,780,841NCBIRnor6.0
Rnor_5.01242,647,011 - 42,647,956UniSTSRnor5.0
Celera1236,915,307 - 36,916,252UniSTS
Cytogenetic Map12q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_001079719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010056782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010056783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000001826   ⟹   ENSRNOP00000001826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1235,182,154 - 35,288,875 (-)Ensembl
Rnor_6.0 Ensembl1240,713,841 - 40,822,159 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109636   ⟹   ENSRNOP00000084673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1240,843,770 - 40,991,798 (-)Ensembl
mRatBN7.2 Ensembl1235,182,154 - 35,330,987 (-)Ensembl
RefSeq Acc Id: XM_017598533   ⟹   XP_017454022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,991,581 (-)NCBI
mRatBN7.21235,182,165 - 35,330,933 (-)NCBI
Rnor_6.01240,712,078 - 40,860,930 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089872   ⟹   XP_038945800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,991,581 (-)NCBI
mRatBN7.21235,182,165 - 35,330,934 (-)NCBI
RefSeq Acc Id: XM_039089873   ⟹   XP_038945801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,991,582 (-)NCBI
mRatBN7.21235,182,165 - 35,330,934 (-)NCBI
RefSeq Acc Id: XM_039089874   ⟹   XP_038945802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,991,582 (-)NCBI
mRatBN7.21235,182,165 - 35,330,934 (-)NCBI
RefSeq Acc Id: XM_039089875   ⟹   XP_038945803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,991,581 (-)NCBI
mRatBN7.21235,182,165 - 35,330,933 (-)NCBI
RefSeq Acc Id: XM_039089876   ⟹   XP_038945804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,991,581 (-)NCBI
mRatBN7.21235,182,165 - 35,330,933 (-)NCBI
RefSeq Acc Id: XM_039089877   ⟹   XP_038945805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,991,581 (-)NCBI
mRatBN7.21235,182,165 - 35,330,933 (-)NCBI
RefSeq Acc Id: XM_039089878   ⟹   XP_038945806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,991,581 (-)NCBI
mRatBN7.21235,182,165 - 35,330,933 (-)NCBI
RefSeq Acc Id: XM_039089879   ⟹   XP_038945807
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,947,429 (-)NCBI
mRatBN7.21235,182,165 - 35,286,771 (-)NCBI
RefSeq Acc Id: XM_039089880   ⟹   XP_038945808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,914,426 (-)NCBI
mRatBN7.21235,182,165 - 35,253,821 (-)NCBI
RefSeq Acc Id: XM_039089882   ⟹   XP_038945810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,905,954 (-)NCBI
mRatBN7.21235,182,165 - 35,245,322 (-)NCBI
RefSeq Acc Id: XM_063271893   ⟹   XP_063127963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,842,809 - 40,991,581 (-)NCBI
RefSeq Acc Id: XR_010056782
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,850,403 - 40,991,584 (-)NCBI
RefSeq Acc Id: XR_010056783
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,800,232 - 40,991,584 (-)NCBI
RefSeq Acc Id: XP_017454022   ⟸   XM_017598533
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZZM0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001826   ⟸   ENSRNOT00000001826
RefSeq Acc Id: XP_038945802   ⟸   XM_039089874
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZZM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945801   ⟸   XM_039089873
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZZM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945800   ⟸   XM_039089872
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945803   ⟸   XM_039089875
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZZM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945806   ⟸   XM_039089878
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZZM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945805   ⟸   XM_039089877
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZZM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945804   ⟸   XM_039089876
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZZM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945807   ⟸   XM_039089879
- Peptide Label: isoform X10
- UniProtKB: F1LZX5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945808   ⟸   XM_039089880
- Peptide Label: isoform X11
- UniProtKB: F1LZX5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945810   ⟸   XM_039089882
- Peptide Label: isoform X12
Ensembl Acc Id: ENSRNOP00000084673   ⟸   ENSRNOT00000109636
RefSeq Acc Id: XP_063127963   ⟸   XM_063271893
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZZM0 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309762 AgrOrtholog
BioCyc Gene G2FUF-19204 BioCyc
Ensembl Genes ENSRNOG00000001352 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000109636 ENTREZGENE
  ENSRNOT00000109636.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domain UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domain UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domains UniProtKB/TrEMBL
InterPro B30.2/SPRY_sf UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
  Hect_E3_ubiquitin_ligase UniProtKB/TrEMBL
  HECTD4 UniProtKB/TrEMBL
  SPRY_HECTD4 UniProtKB/TrEMBL
NCBI Gene 304503 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED UniProtKB/TrEMBL
  PTHR46435 UniProtKB/TrEMBL
Pfam HECT UniProtKB/TrEMBL
PhenoGen Hectd4 PhenoGen
PROSITE HECT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001352 RatGTEx
SMART HECTc UniProtKB/TrEMBL
Superfamily-SCOP HECT UniProtKB/TrEMBL
UniProt A0A8I5ZZM0 ENTREZGENE, UniProtKB/TrEMBL
  F1LZX5 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-15 Hectd4  HECT domain E3 ubiquitin protein ligase 4  Hectd4  HECT domain containing E3 ubiquitin protein ligase 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-10 Hectd4  HECT domain containing E3 ubiquitin protein ligase 4  RGD1309762  similar to KIAA0614 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1309762  similar to KIAA0614 protein   RGD1309762_predicted  similar to KIAA0614 protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1309762_predicted  similar to KIAA0614 protein (predicted)  LOC304503_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC304503_predicted  similar to KIAA0614 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL