Tbrg4 (transforming growth factor beta regulator 4) - Rat Genome Database

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Gene: Tbrg4 (transforming growth factor beta regulator 4) Rattus norvegicus
Analyze
Symbol: Tbrg4
Name: transforming growth factor beta regulator 4
RGD ID: 1309737
Description: Predicted to enable RNA binding activity. Predicted to be involved in mitochondrial mRNA processing and regulation of mitochondrial mRNA stability. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Orthologous to human TBRG4 (transforming growth factor beta regulator 4); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FAST kinase domain-containing protein 4; LOC360977; transforming growth factor beta regulated gene 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,696,738 - 85,704,691 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1485,695,893 - 85,704,659 (-)EnsemblGRCr8
mRatBN7.21481,481,977 - 81,490,781 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,481,981 - 81,490,756 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,884,110 - 85,890,101 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,123,913 - 87,129,904 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01483,573,509 - 83,579,500 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,876,800 - 86,885,603 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,877,627 - 86,885,584 (-)Ensemblrn6Rnor6.0
Rnor_5.01480,510,244 - 80,519,046 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41487,372,275 - 87,378,266 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1480,364,375 - 80,370,366 (-)NCBICelera
RGSC_v3.11487,391,420 - 87,397,411 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP)
caffeine  (EXP)
carbon nanotube  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
corosolic acid  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hypochlorous acid  (ISO)
ivermectin  (ISO)
methimazole  (EXP)
methoxyacetic acid  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (EXP)
Monobutylphthalate  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrial matrix  (IBA,IEA,ISO,ISS)
mitochondrion  (IEA,ISO,ISS)
ribonucleoprotein granule  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration. Simarro M, etal., Biochem Biophys Res Commun. 2010 Oct 22;401(3):440-6. doi: 10.1016/j.bbrc.2010.09.075. Epub 2010 Sep 24.
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:18614015   PMID:22658674   PMID:22681889   PMID:28335001  


Genomics

Comparative Map Data
Tbrg4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,696,738 - 85,704,691 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1485,695,893 - 85,704,659 (-)EnsemblGRCr8
mRatBN7.21481,481,977 - 81,490,781 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,481,981 - 81,490,756 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,884,110 - 85,890,101 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,123,913 - 87,129,904 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01483,573,509 - 83,579,500 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,876,800 - 86,885,603 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,877,627 - 86,885,584 (-)Ensemblrn6Rnor6.0
Rnor_5.01480,510,244 - 80,519,046 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41487,372,275 - 87,378,266 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1480,364,375 - 80,370,366 (-)NCBICelera
RGSC_v3.11487,391,420 - 87,397,411 (-)NCBI
Cytogenetic Map14q21NCBI
TBRG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38745,100,100 - 45,111,697 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl745,097,584 - 45,112,048 (-)Ensemblhg38GRCh38
GRCh37745,139,699 - 45,151,296 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,106,224 - 45,117,842 (-)NCBIBuild 36Build 36hg18NCBI36
Celera745,238,535 - 45,250,160 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef745,023,497 - 45,035,149 (-)NCBIHuRef
CHM1_1745,143,388 - 45,155,037 (-)NCBICHM1_1
T2T-CHM13v2.0745,260,901 - 45,272,500 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2745,178,869 - 45,190,516 (-)NCBI
Tbrg4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39116,565,598 - 6,576,089 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl116,565,598 - 6,576,067 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38116,615,598 - 6,626,084 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl116,615,598 - 6,626,067 (-)Ensemblmm10GRCm38
MGSCv37116,515,601 - 6,526,070 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36116,516,426 - 6,526,026 (-)NCBIMGSCv36mm8
Celera1118,688,824 - 18,699,295 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.6NCBI
Tbrg4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,199,560 - 7,208,808 (+)Ensembl
ChiLan1.0NW_0049554567,197,690 - 7,207,102 (+)NCBIChiLan1.0ChiLan1.0
TBRG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2650,012,972 - 50,025,481 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1798,337,710 - 98,349,655 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0745,813,586 - 45,825,311 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1745,879,666 - 45,891,651 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl745,879,666 - 45,891,351 (-)EnsemblpanPan2panpan1.1
TBRG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,628,800 - 2,637,420 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01614,223,466 - 14,232,086 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,223,504 - 14,233,730 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01613,856,374 - 13,864,994 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01613,835,830 - 13,844,452 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tbrg4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118100,694,500 - 100,704,165 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,902,337 - 19,915,858 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,906,227 - 19,915,815 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBRG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,365,988 - 50,378,084 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11850,366,896 - 50,378,086 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,197,834 - 55,209,038 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBRG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12113,570,061 - 13,581,824 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2113,570,127 - 13,581,612 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660628,947,494 - 8,959,522 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbrg4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,277,180 - 7,286,338 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247407,277,254 - 7,287,073 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tbrg4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11175,546,214 - 75,554,359 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tbrg4
33 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:414
Count of miRNA genes:229
Interacting mature miRNAs:273
Transcripts:ENSRNOT00000057144
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat

Markers in Region
D14Rat136  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81485,696,526 - 85,696,754 (+)Marker Load Pipeline
mRatBN7.21481,482,611 - 81,482,839 (+)MAPPERmRatBN7.2
Rnor_6.01486,877,435 - 86,877,662NCBIRnor6.0
Rnor_5.01480,510,879 - 80,511,106UniSTSRnor5.0
RGSC_v3.41487,372,063 - 87,372,291RGDRGSC3.4
RGSC_v3.41487,372,064 - 87,372,291UniSTSRGSC3.4
RGSC_v3.11487,390,913 - 87,391,462RGD
FHH x ACI Map1463.6199UniSTS
FHH x ACI Map1463.6199RGD
Cytogenetic Map14q21UniSTS
RH125754  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21481,482,835 - 81,483,086 (+)MAPPERmRatBN7.2
Rnor_6.01486,877,659 - 86,877,909NCBIRnor6.0
Rnor_5.01480,511,103 - 80,511,353UniSTSRnor5.0
RGSC_v3.41487,372,288 - 87,372,538UniSTSRGSC3.4
Celera1480,364,388 - 80,364,638UniSTS
Cytogenetic Map14q21UniSTS
RH135073  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21481,482,074 - 81,482,273 (+)MAPPERmRatBN7.2
Rnor_6.01486,876,898 - 86,877,096NCBIRnor6.0
Rnor_5.01480,510,342 - 80,510,540UniSTSRnor5.0
RGSC_v3.41487,371,527 - 87,371,725UniSTSRGSC3.4
RH 3.4 Map14583.1UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000089133   ⟹   ENSRNOP00000074223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1485,695,893 - 85,704,659 (-)Ensembl
mRatBN7.2 Ensembl1481,481,981 - 81,490,756 (-)Ensembl
Rnor_6.0 Ensembl1486,877,627 - 86,885,584 (-)Ensembl
RefSeq Acc Id: NM_001012154   ⟹   NP_001012154
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,696,738 - 85,702,729 (-)NCBI
mRatBN7.21481,482,823 - 81,488,814 (-)NCBI
Rnor_6.01486,877,646 - 86,883,637 (-)NCBI
Rnor_5.01480,510,244 - 80,519,046 (-)NCBI
RGSC_v3.41487,372,275 - 87,378,266 (-)RGD
Celera1480,364,375 - 80,370,366 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251343   ⟹   XP_006251405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,696,738 - 85,704,682 (-)NCBI
mRatBN7.21481,481,978 - 81,490,781 (-)NCBI
Rnor_6.01486,876,801 - 86,885,597 (-)NCBI
Rnor_5.01480,510,244 - 80,519,046 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092223   ⟹   XP_038948151
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,696,738 - 85,704,603 (-)NCBI
mRatBN7.21481,481,978 - 81,490,692 (-)NCBI
RefSeq Acc Id: XM_039092225   ⟹   XP_038948153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,696,738 - 85,704,691 (-)NCBI
mRatBN7.21481,481,978 - 81,490,776 (-)NCBI
RefSeq Acc Id: XM_039092227   ⟹   XP_038948155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,696,738 - 85,701,643 (-)NCBI
mRatBN7.21481,481,978 - 81,490,750 (-)NCBI
RefSeq Acc Id: NP_001012154   ⟸   NM_001012154
- UniProtKB: Q5M9G9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006251405   ⟸   XM_006251343
- Peptide Label: isoform X1
- UniProtKB: Q5M9G9 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074223   ⟸   ENSRNOT00000089133
RefSeq Acc Id: XP_038948153   ⟸   XM_039092225
- Peptide Label: isoform X2
- UniProtKB: A6IKV6 (UniProtKB/TrEMBL),   A6IKV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948155   ⟸   XM_039092227
- Peptide Label: isoform X3
- UniProtKB: A6IKV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948151   ⟸   XM_039092223
- Peptide Label: isoform X1
- UniProtKB: Q5M9G9 (UniProtKB/Swiss-Prot)
Protein Domains
RAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M9G9-F1-model_v2 AlphaFold Q5M9G9 1-629 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699480
Promoter ID:EPDNEW_R10004
Type:multiple initiation site
Name:Tbrg4_1
Description:transforming growth factor beta regulator 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,885,575 - 86,885,635EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309737 AgrOrtholog
BioCyc Gene G2FUF-15070 BioCyc
Ensembl Genes ENSRNOG00000052477 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000089133 ENTREZGENE
  ENSRNOT00000089133.2 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134456 IMAGE-MGC_LOAD
InterPro FAST_2 UniProtKB/Swiss-Prot
  FAST_kinase UniProtKB/Swiss-Prot
  FAST_Leu-rich UniProtKB/Swiss-Prot
  RAP UniProtKB/Swiss-Prot
KEGG Report rno:360977 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94428 IMAGE-MGC_LOAD
NCBI Gene 360977 ENTREZGENE
PANTHER FAST KINASE DOMAIN-CONTAINING PROTEIN 4 UniProtKB/Swiss-Prot
  FAST LEU-RICH DOMAIN-CONTAINING UniProtKB/Swiss-Prot
Pfam FAST_1 UniProtKB/Swiss-Prot
  FAST_2 UniProtKB/Swiss-Prot
  RAP UniProtKB/Swiss-Prot
PhenoGen Tbrg4 PhenoGen
PROSITE RAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000052477 RatGTEx
SMART RAP UniProtKB/Swiss-Prot
UniProt A6IKV6 ENTREZGENE, UniProtKB/TrEMBL
  A6IKV7 ENTREZGENE, UniProtKB/TrEMBL
  FAKD4_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Tbrg4  transforming growth factor beta regulator 4  Tbrg4  transforming growth factor beta regulated gene 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Tbrg4  transforming growth factor beta regulated gene 4  Tbrg4_predicted  transforming growth factor beta regulated gene 4 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tbrg4_predicted  transforming growth factor beta regulated gene 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED