Tmem175 (transmembrane protein 175) - Rat Genome Database

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Pathways
Gene: Tmem175 (transmembrane protein 175) Rattus norvegicus
Analyze
Symbol: Tmem175
Name: transmembrane protein 175
RGD ID: 1309712
Description: Predicted to enable arachidonate binding activity; potassium ion leak channel activity; and proton channel activity. Predicted to be involved in lysosome organization; monoatomic cation transmembrane transport; and neuron cellular homeostasis. Predicted to be located in endosome membrane and lysosomal membrane. Predicted to be active in endosome and lysosome. Orthologous to human TMEM175 (transmembrane protein 175); INTERACTS WITH acrylamide; bisphenol A; paracetamol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: endosomal/lysomomal potassium channel TMEM175; endosomal/lysosomal potassium channel TMEM175; endosomal/lysosomal proton channel TMEM175; LOC305623; potassium channel TMEM175; RGD1309712; similar to RIKEN cDNA 3010001K23 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8141,217,911 - 1,234,236 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl141,217,914 - 1,234,018 (-)EnsemblGRCr8
mRatBN7.2141,073,410 - 1,089,764 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl141,073,523 - 1,089,819 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx14973,404 - 989,349 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0142,275,182 - 2,291,127 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014971,877 - 987,822 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0142,083,745 - 2,100,006 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl142,083,712 - 2,100,005 (-)Ensemblrn6Rnor6.0
Rnor_5.0142,078,799 - 2,095,561 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4141,614,529 - 1,630,636 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera141,112,847 - 1,128,959 (-)NCBICelera
RGSC_v3.1141,614,529 - 1,630,636 (-)NCBI
Cytogenetic Map14p22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
endosome  (IBA,IEA,ISO,ISS)
endosome membrane  (IEA,ISO,ISS)
lysosomal membrane  (IEA,ISO,ISS)
lysosome  (IBA,IEA,ISO,ISS)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:17897319   PMID:26317472   PMID:28193887   PMID:28723891   PMID:32799888  


Genomics

Comparative Map Data
Tmem175
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8141,217,911 - 1,234,236 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl141,217,914 - 1,234,018 (-)EnsemblGRCr8
mRatBN7.2141,073,410 - 1,089,764 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl141,073,523 - 1,089,819 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx14973,404 - 989,349 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0142,275,182 - 2,291,127 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014971,877 - 987,822 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0142,083,745 - 2,100,006 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl142,083,712 - 2,100,005 (-)Ensemblrn6Rnor6.0
Rnor_5.0142,078,799 - 2,095,561 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4141,614,529 - 1,630,636 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera141,112,847 - 1,128,959 (-)NCBICelera
RGSC_v3.1141,614,529 - 1,630,636 (-)NCBI
Cytogenetic Map14p22NCBI
TMEM175
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384932,460 - 958,656 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4932,168 - 958,741 (+)Ensemblhg38GRCh38
GRCh374926,248 - 952,444 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364916,262 - 942,444 (+)NCBIBuild 36Build 36hg18NCBI36
Celera4863,168 - 889,353 (+)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef4897,477 - 923,812 (+)NCBIHuRef
CHM1_14925,472 - 952,228 (+)NCBICHM1_1
T2T-CHM13v2.04930,532 - 956,764 (+)NCBIT2T-CHM13v2.0
Tmem175
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395108,777,649 - 108,795,636 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5108,777,636 - 108,796,648 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385108,629,779 - 108,647,770 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5108,629,770 - 108,648,782 (+)Ensemblmm10GRCm38
MGSCv375109,058,829 - 109,076,789 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365108,870,304 - 108,887,565 (+)NCBIMGSCv36mm8
Celera5105,751,308 - 105,769,349 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map553.24NCBI
Tmem175
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955514434,285 - 453,239 (+)Ensembl
ChiLan1.0NW_004955514434,283 - 453,239 (+)NCBIChiLan1.0ChiLan1.0
TMEM175
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v231,262,300 - 1,287,866 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan141,228,124 - 1,255,224 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v041,049,647 - 1,074,903 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14967,494 - 993,030 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4967,494 - 993,030 (+)EnsemblpanPan2panpan1.1
TMEM175
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1391,554,001 - 91,576,845 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl391,553,778 - 91,670,930 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha394,019,059 - 94,042,095 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0392,551,080 - 92,575,365 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl392,551,080 - 92,670,555 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1391,724,345 - 91,746,694 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0391,777,372 - 91,800,395 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0392,161,193 - 92,184,240 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tmem175
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528568,537,401 - 68,552,335 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647722,239,093 - 22,254,439 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647722,239,093 - 22,254,028 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM175
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8297,007 - 313,972 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.18295,693 - 313,974 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TMEM175
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12747,819,512 - 47,852,455 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2747,816,482 - 47,852,472 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660514,157,175 - 4,214,288 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem175
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475526,190,547 - 26,207,793 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475526,190,547 - 26,200,512 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Tmem175
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11118,415,497 - 18,434,559 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tmem175
81 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:23
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000000050
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14111334906Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14117877928Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat

Markers in Region
BI276490  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2141,073,550 - 1,073,706 (+)MAPPERmRatBN7.2
Rnor_6.0142,083,790 - 2,083,945NCBIRnor6.0
Rnor_5.0142,079,333 - 2,079,488UniSTSRnor5.0
RGSC_v3.4141,614,574 - 1,614,729UniSTSRGSC3.4
Celera141,112,892 - 1,113,047UniSTS
Cytogenetic Map14p22UniSTS
RH129524  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8141,217,411 - 1,217,621 (+)Marker Load Pipeline
mRatBN7.2141,073,006 - 1,073,216 (+)MAPPERmRatBN7.2
Rnor_6.0142,083,246 - 2,083,455NCBIRnor6.0
Rnor_5.0142,078,789 - 2,078,998UniSTSRnor5.0
RGSC_v3.4141,614,030 - 1,614,239UniSTSRGSC3.4
Celera141,112,348 - 1,112,557UniSTS
Cytogenetic Map14p22UniSTS
RH135170  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2141,073,641 - 1,073,843 (+)MAPPERmRatBN7.2
Rnor_6.0142,083,881 - 2,084,082NCBIRnor6.0
Rnor_5.0142,079,424 - 2,079,625UniSTSRnor5.0
RGSC_v3.4141,614,665 - 1,614,866UniSTSRGSC3.4
Celera141,112,983 - 1,113,184UniSTS
Cytogenetic Map14p22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001013991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC117047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000000050   ⟹   ENSRNOP00000000050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl141,217,914 - 1,234,018 (-)Ensembl
mRatBN7.2 Ensembl141,073,523 - 1,089,819 (-)Ensembl
Rnor_6.0 Ensembl142,083,712 - 2,100,005 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094320   ⟹   ENSRNOP00000080137
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl141,221,508 - 1,234,018 (-)Ensembl
mRatBN7.2 Ensembl141,077,103 - 1,089,819 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114727   ⟹   ENSRNOP00000082603
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl141,217,914 - 1,234,018 (-)Ensembl
mRatBN7.2 Ensembl141,073,523 - 1,089,819 (-)Ensembl
RefSeq Acc Id: NM_001013991   ⟹   NP_001014013
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,911 - 1,234,018 (-)NCBI
mRatBN7.2141,073,506 - 1,089,613 (-)NCBI
Rnor_6.0142,083,745 - 2,099,852 (-)NCBI
Rnor_5.0142,078,799 - 2,095,561 (-)NCBI
RGSC_v3.4141,614,529 - 1,630,636 (-)RGD
Celera141,112,847 - 1,128,959 (-)RGD
Sequence:
RefSeq Acc Id: XM_006250558   ⟹   XP_006250620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,234,181 (-)NCBI
mRatBN7.2141,073,410 - 1,089,572 (-)NCBI
Rnor_6.0142,083,756 - 2,099,811 (-)NCBI
Rnor_5.0142,078,799 - 2,095,561 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599261   ⟹   XP_017454750
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,234,236 (-)NCBI
mRatBN7.2141,073,410 - 1,089,762 (-)NCBI
Rnor_6.0142,083,756 - 2,100,006 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599263   ⟹   XP_017454752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,234,153 (-)NCBI
mRatBN7.2141,073,410 - 1,089,764 (-)NCBI
Rnor_6.0142,083,756 - 2,100,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092128   ⟹   XP_038948056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,234,181 (-)NCBI
mRatBN7.2141,073,410 - 1,089,762 (-)NCBI
RefSeq Acc Id: XM_039092130   ⟹   XP_038948058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,222,607 (-)NCBI
mRatBN7.2141,073,410 - 1,077,729 (-)NCBI
RefSeq Acc Id: XM_063273296   ⟹   XP_063129366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,234,181 (-)NCBI
RefSeq Acc Id: XM_063273297   ⟹   XP_063129367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,234,181 (-)NCBI
RefSeq Acc Id: XM_063273298   ⟹   XP_063129368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,234,181 (-)NCBI
RefSeq Acc Id: XM_063273300   ⟹   XP_063129370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,234,124 (-)NCBI
RefSeq Acc Id: XM_063273301   ⟹   XP_063129371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8141,217,926 - 1,234,124 (-)NCBI
RefSeq Acc Id: NP_001014013   ⟸   NM_001013991
- UniProtKB: Q6AY05 (UniProtKB/Swiss-Prot),   A6KPE4 (UniProtKB/TrEMBL),   A0A8I5ZUF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250620   ⟸   XM_006250558
- Peptide Label: isoform X1
- UniProtKB: Q6AY05 (UniProtKB/Swiss-Prot),   A6KPE4 (UniProtKB/TrEMBL),   A0A8I5ZUF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454750   ⟸   XM_017599261
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZUF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454752   ⟸   XM_017599263
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZUF0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000000050   ⟸   ENSRNOT00000000050
RefSeq Acc Id: XP_038948056   ⟸   XM_039092128
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948058   ⟸   XM_039092130
- Peptide Label: isoform X7
Ensembl Acc Id: ENSRNOP00000080137   ⟸   ENSRNOT00000094320
Ensembl Acc Id: ENSRNOP00000082603   ⟸   ENSRNOT00000114727
RefSeq Acc Id: XP_063129368   ⟸   XM_063273298
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZUF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129366   ⟸   XM_063273296
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129367   ⟸   XM_063273297
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZUF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129371   ⟸   XM_063273301
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063129370   ⟸   XM_063273300
- Peptide Label: isoform X6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY05-F1-model_v2 AlphaFold Q6AY05 1-499 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699146
Promoter ID:EPDNEW_R9670
Type:initiation region
Name:Tmem175_2
Description:transmembrane protein 175
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9671  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0142,099,820 - 2,099,880EPDNEW
RGD ID:13699147
Promoter ID:EPDNEW_R9671
Type:initiation region
Name:Tmem175_1
Description:transmembrane protein 175
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9670  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0142,099,996 - 2,100,056EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309712 AgrOrtholog
BioCyc Gene G2FUF-16682 BioCyc
Ensembl Genes ENSRNOG00000000044 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000000050 ENTREZGENE
  ENSRNOT00000000050.7 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7132812 IMAGE-MGC_LOAD
InterPro TMEM175 UniProtKB/Swiss-Prot
KEGG Report rno:305623 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94332 IMAGE-MGC_LOAD
NCBI Gene 305623 ENTREZGENE
PANTHER ENDOSOMAL/LYSOSOMAL POTASSIUM CHANNEL TMEM175 UniProtKB/Swiss-Prot
  ENDOSOMAL/LYSOSOMAL POTASSIUM CHANNEL TMEM175 UniProtKB/Swiss-Prot
Pfam DUF1211 UniProtKB/Swiss-Prot
PhenoGen Tmem175 PhenoGen
RatGTEx ENSRNOG00000000044 RatGTEx
UniProt A0A8I5ZPE6_RAT UniProtKB/TrEMBL
  A0A8I5ZUF0 ENTREZGENE, UniProtKB/TrEMBL
  A6KPE4 ENTREZGENE, UniProtKB/TrEMBL
  Q6AY05 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-26 Tmem175  transmembrane protein 175  RGD1309712  similar to RIKEN cDNA 3010001K23 gene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1309712  similar to RIKEN cDNA 3010001K23 gene  RGD1309712_predicted  similar to RIKEN cDNA 3010001K23 gene (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309712_predicted  similar to RIKEN cDNA 3010001K23 gene (predicted)  LOC305623_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC305623_predicted  similar to RIKEN cDNA 3010001K23 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL