Mvb12b (multivesicular body subunit 12B)

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Gene: Mvb12b (multivesicular body subunit 12B) Rattus norvegicus

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Symbol:

Mvb12b

Name:

multivesicular body subunit 12B

RGD ID:

1309709

Description:

Predicted to enable lipid binding activity. Predicted to be involved in regulation of epidermal growth factor receptor signaling pathway; viral budding; and virus maturation. Predicted to be located in several cellular components, including cytosol; early endosome; and nucleus. Predicted to be part of ESCRT I complex. Predicted to be active in late endosome. Orthologous to human MVB12B (multivesicular body subunit 12B); PARTICIPATES IN endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Fam125b; family with sequence similarity 125, member B; LOC362118; RGD1309709; similar to FLJ00022 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MVB12B (multivesicular body subunit 12B)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Mvb12b (multivesicular body subunit 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mvb12b (multivesicular body subunit 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MVB12B (multivesicular body subunit 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MVB12B (multivesicular body subunit 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mvb12b (multivesicular body subunit 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MVB12B (multivesicular body subunit 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MVB12B (multivesicular body subunit 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mvb12b (multivesicular body subunit 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	KIAA1217 (KIAA1217)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	MVB12B (multivesicular body subunit 12B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mvb12b (multivesicular body subunit 12B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mvb12ba (multivesicular body subunit 12Ba)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mvb-12	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Mvb12	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	mvb12b	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	37,431,636 - 37,590,276 (-)	NCBI		GRCr8
mRatBN7.2	3	17,034,002 - 17,192,658 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	17,034,003 - 17,193,202 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	20,105,920 - 20,262,550 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	28,690,974 - 28,847,616 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	26,941,923 - 27,098,540 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	12,780,196 - 12,944,542 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	12,780,100 - 12,944,494 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	18,114,157 - 18,274,679 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	12,749,857 - 12,905,606 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	12,646,228 - 12,827,259 (-)	NCBI
Celera	3	11,768,930 - 11,909,397 (-)	NCBI		Celera
Cytogenetic Map	3	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

nail-patella syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4,6-tribromophenol (ISO)

2-methylcholine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (EXP,ISO)

Aflatoxin B2 alpha (ISO)

aristolochic acid A (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

C60 fullerene (EXP)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

clobetasol (ISO)

copper atom (ISO)

copper(0) (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

flutamide (EXP)

fulvestrant (ISO)

gentamycin (EXP)

glyphosate (EXP)

lipopolysaccharide (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methoxychlor (EXP)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

urethane (ISO)

valproic acid (ISO)

versicolorin A (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein transport (IEA)

regulation of epidermal growth factor receptor signaling pathway (IBA,ISO)

viral budding (IBA)

virus maturation (IBA)

Cellular Component

cytosol (ISO)

early endosome (ISO)

ESCRT I complex (IBA,ISO)

late endosome (IBA,ISO)

late endosome membrane (IEA)

nucleus (ISO)

plasma membrane (ISO)

vesicle (ISO)

Molecular Function

lipid binding (ISO)

protein binding (ISO)

ubiquitin binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

endocytosis pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:18005716	PMID:19056867	PMID:20654576	PMID:22232651	PMID:23376485

Genomics

Comparative Map Data

Mvb12b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	37,431,636 - 37,590,276 (-)	NCBI		GRCr8
mRatBN7.2	3	17,034,002 - 17,192,658 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	17,034,003 - 17,193,202 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	20,105,920 - 20,262,550 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	28,690,974 - 28,847,616 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	26,941,923 - 27,098,540 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	12,780,196 - 12,944,542 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	12,780,100 - 12,944,494 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	18,114,157 - 18,274,679 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	12,749,857 - 12,905,606 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	12,646,228 - 12,827,259 (-)	NCBI
Celera	3	11,768,930 - 11,909,397 (-)	NCBI		Celera
Cytogenetic Map	3	p11	NCBI

MVB12B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	126,326,829 - 126,507,040 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	126,326,829 - 126,507,041 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	129,089,108 - 129,269,319 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	128,128,949 - 128,309,140 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	9	99,743,357 - 99,922,950 (+)	NCBI		Celera
Cytogenetic Map	9	q33.3	NCBI
HuRef	9	98,706,516 - 98,885,863 (+)	NCBI		HuRef
CHM1_1	9	129,240,183 - 129,420,105 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	138,532,595 - 138,712,489 (+)	NCBI		T2T-CHM13v2.0

Mvb12b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	33,619,965 - 33,777,958 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	33,619,965 - 33,777,958 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	33,729,953 - 33,887,946 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	33,729,953 - 33,887,946 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	33,585,476 - 33,743,466 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	33,551,965 - 33,709,955 (-)	NCBI		MGSCv36	mm8
Celera	2	33,436,193 - 33,594,588 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	22.51	NCBI

Mvb12b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	1,949,156 - 2,104,098 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	1,949,211 - 2,116,525 (-)	NCBI	ChiLan1.0	ChiLan1.0

MVB12B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	12,850,865 - 13,031,034 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	12,853,210 - 13,033,162 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	97,444,439 - 97,624,085 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	125,953,845 - 126,133,369 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	125,953,845 - 126,133,369 (+)	Ensembl	panpan1.1		panPan2

MVB12B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	56,721,599 - 56,908,723 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	56,707,258 - 56,907,716 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	55,924,217 - 56,109,721 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	57,643,475 - 57,828,981 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	57,642,447 - 57,828,991 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	56,402,645 - 56,588,170 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	56,716,906 - 56,903,564 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	56,808,872 - 56,994,571 (-)	NCBI		UU_Cfam_GSD_1.0

Mvb12b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	194,497,648 - 194,663,158 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	14,277,942 - 14,431,709 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	14,178,299 - 14,431,687 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MVB12B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	266,933,542 - 267,105,788 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	266,933,459 - 267,105,790 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	300,987,894 - 301,005,171 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MVB12B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	11,639,784 - 11,816,005 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	11,636,244 - 11,809,074 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666079	4,371,031 - 4,550,005 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mvb12b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	8,864,983 - 9,019,264 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	8,862,620 - 9,021,432 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mvb12b
879 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1597
Count of miRNA genes:	329
Interacting mature miRNAs:	447
Transcripts:	ENSRNOT00000023172, ENSRNOT00000075029
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	8658162	27494778	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
11528620	Bss113	Bone structure and strength QTL 113	9.75	2e-10	femur morphology trait (VT:0000559)	femoral neck width (CMO:0001695)	3	16490648	19241681	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	8227194	47233430	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	8227194	33703538	Rat
8693641	Alc30	Alcohol consumption QTL 30	2	0.739	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	3	10434306	24512004	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	15005422	76927699	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	39874793	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	pulse pressure (CMO:0000292)	3	1	33278763	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	1	33230976	Rat
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	36847613	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	10778823	30356773	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	10778704	50302886	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	16954708	61954708	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	1	31158234	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	8658162	27494778	Rat
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	1	27494778	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	38710544	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat

Markers in Region

RH128865

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	17,034,084 - 17,034,294 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	12,780,280 - 12,780,489	NCBI	Rnor6.0
Rnor_5.0	3	18,111,211 - 18,111,420	UniSTS	Rnor5.0
RGSC_v3.4	3	12,746,544 - 12,746,753	UniSTS	RGSC3.4
Celera	3	11,765,984 - 11,766,193	UniSTS
RH 3.4 Map	3	122.0	UniSTS
Cytogenetic Map	3	p11	UniSTS

AW531477

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	17,179,026 - 17,179,224 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	12,930,917 - 12,931,114	NCBI	Rnor6.0
Rnor_5.0	3	18,261,054 - 18,261,251	UniSTS	Rnor5.0
RGSC_v3.4	3	12,892,036 - 12,892,233	UniSTS	RGSC3.4
Celera	3	11,908,656 - 11,908,853	UniSTS
RH 3.4 Map	3	129.4	UniSTS
Cytogenetic Map	3	p11	UniSTS

RH137927

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	17,189,932 - 17,190,059 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	12,941,817 - 12,941,943	NCBI	Rnor6.0
Rnor_5.0	3	18,271,954 - 18,272,080	UniSTS	Rnor5.0
RGSC_v3.4	3	12,902,936 - 12,903,062	UniSTS	RGSC3.4
Celera	3	11,919,553 - 11,919,679	UniSTS
RH 3.4 Map	3	129.4	UniSTS
Cytogenetic Map	3	p11	UniSTS

RH137974

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	17,243,124 - 17,243,314 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	12,995,290 - 12,995,479	NCBI	Rnor6.0
Rnor_5.0	3	18,324,896 - 18,325,085	UniSTS	Rnor5.0
RGSC_v3.4	3	12,958,513 - 12,958,702	UniSTS	RGSC3.4
Celera	3	11,972,547 - 11,972,736	UniSTS
RH 3.4 Map	3	119.32	UniSTS
Cytogenetic Map	3	p11	UniSTS

RH141967

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	17,241,460 - 17,241,680 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	12,993,626 - 12,993,845	NCBI	Rnor6.0
Rnor_5.0	3	18,323,232 - 18,323,451	UniSTS	Rnor5.0
RGSC_v3.4	3	12,956,849 - 12,957,068	UniSTS	RGSC3.4
Celera	3	11,970,883 - 11,971,102	UniSTS
RH 3.4 Map	3	127.8	UniSTS
Cytogenetic Map	3	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001271232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000023172 ⟹ ENSRNOP00000023172

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	17,034,003 - 17,193,202 (-)	Ensembl
Rnor_6.0 Ensembl	3	12,780,100 - 12,944,494 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105862 ⟹ ENSRNOP00000089240

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	17,107,232 - 17,192,658 (-)	Ensembl

RefSeq Acc Id:

NM_001271232 ⟹ NP_001258161

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	37,434,664 - 37,590,276 (-)	NCBI
mRatBN7.2	3	17,037,031 - 17,192,658 (-)	NCBI
Rnor_6.0	3	12,783,226 - 12,944,542 (-)	NCBI
Rnor_5.0	3	18,114,157 - 18,274,679 (-)	NCBI
Celera	3	11,768,930 - 11,909,397 (-)	NCBI

Sequence:

show sequence

CGCCGGCTGCAGCCGCCTGGGCCCCGGGCCCGGCTCCTCCCGCGCCGCCCGGGCGATGAGAAGC
TGCTTCTGCGTGAGACGGAGCCGGGACCCGCCGCCGCCGCAGCCGCCGCCGCCCCAGCGGGGAA
CAGACCAAGCCACCATGCCTGAAGTCAAAGAGCTTTCAGAAGCCTTGCCAGAGACACCAATGGA
CCCCATCACGGGAGTCGGGGTGGTAGCCTCCCGGAACCGAGCGCCGACAGGCTACGATGTGGTT
GCACAGACAGCAGATGGTGTGGACGCTGACCTCTGGAAGGACGGCTTATTCAAATCCAAGGTTA
CCAGATACCTGTGTTTCACAAGATCATTTTCTAAAGAAAACAGTCATTTGGGGAATGTGCTGGT
GGACATGAAACTCATCGACGTCAAGGACACGTTGCCTGTGGGCTTCATTCCCATCCAGGAGACG
GTGGATACACAGGAGGTGGTCTTCAGGAAGAAGAGGCTATGCATTAAGTTCATTCCCCGGGATT
CAACCGAAGCCGCCATTTGTGACATTCGCATCATGGGCCGGACCAAGCAGGCTCCTCCCCAGTA
CACATTTATCGGGGAACTGAACAGCATGGGCATCTGGTATCGAATGGGCAGAGTGCCAAGAAAC
CATGACTCATCTCAACCCACCACGCCCTCCCAGTCATCAGCTGCTTCCACCCCAGCCCCAAACC
TTCCCAGGCACATCTCCCTGACACTCCCGGCTACCTTCCGAGGCAGAAACAACACCAGCACAGA
CTATGAGTACCAGCTCTCCAACCTGTATGCCATATCAGCAATGGACGGTGTGCCTTTTATGATT
TCAGAGAAGTTTTCCTGCATCCCAGAAAGTATGCAGCCCTTTGATCTCTTGGGAATCACCATCA
AGTCTCTGGCGGAAATTGAAAAGGAGTACGAGTACAGTTTCCGCACCGAGCAGAGCGCGGCAGC
TCGGCTCCCACCCAGCCCTACCCGGTGCCAGCAGATCCCCCAGTCCTGAGGAGCCCACAGCCTA
CCCGGTGCCCAGACTACTGATGAGGTGGCTGGGGTGAGAGTCACGCCCTCCCTCACCTGCCCAT
TCTGCTTGCCCCTGCTCACTGACCAAGAGACTCTGGGCAGCTGCTTGGTCAGATACGGTCATCA
GCTCGCCTAACGAGACTTCCCTCCCTCCCCGGGAACGTTGTTCATAATTGTGACTAATGTGTGT
GCTGTTAGTGACCAGAGGCTCCTGTGTGATGACCACTTACCCCACCAAGAAAGAAAACTCCTCC
CTTACCTGGAGTCACCCATGAGGGCCTGGGCACATACTCCATCCACCCAGTGACACTCACTGGC
TACCCTCCAACTGACCATCACTGACCACAGAA

hide sequence

RefSeq Acc Id:

XM_017591884 ⟹ XP_017447373

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	37,431,636 - 37,585,150 (-)	NCBI
mRatBN7.2	3	17,034,002 - 17,187,531 (-)	NCBI
Rnor_6.0	3	12,780,196 - 12,940,186 (-)	NCBI

Sequence:

show sequence

TTTTTTTTTTTTCAATGTTGACATCATTAAACAACGCTCTTTCTTAGGGACCCTGGCAACCTCC
ATTCAATTTTCTATCTCCCTGGATGTGACTGTGCTGGGTGCCTTTTGGAGCTGGAATCCTAGGA
TGTGTAGCTTCTTCTGACTGGCTTATTTTGCTTTGCACAGTATCTTCACAGTTCATGGTGTTAT
AGGTCAGATTTTCCTGCCTCTTGAAGGCTGAAGGATGCATGATTGGGCACATTGACTGTATCTC
ACTTACCCGTTCGTCCTATTTTGGCCATTGAATGAGGCTGCTCTGGCAATTCTTTGTCAAATTC
ATGGAGGGTATATAGTTAGAAATGGATCATATGGGGTTGTTATTTTTAATCCTCGGGGGAATTA
ACATACTTTCCCGATAAAGGATGGCTGCTGTGTACACTCCCACCAATAACATCAAAGCTTCTGA
TTTCTCCGTATCCTCCCAACGTTTGTTGCCCTCTGGAGATACCCAGCAGGATGGGTGGAAGACG
CCTCACTGCGGTTTGGGTCTTAACTGGCATTTCACAGGGACTTCAGCATCTTCTGGGCTGCACG
TGGTCCGCGCGCCTCTCAGCCTTGGAGAAACGTTTCTCCAAGTAATTTGGCCACTAAGGATGAA
TACGTGGCCTCTTGTTCAGCTGTAGCTCTTTATGGATATGGATTTAGCTCCTCATCCCATATTG
GGAGCAGATATGACGGGCAAATATTCTCCCAGGGGCCTTTTTACTTTATAGAGTGTGTCCTCTG
ATGCAATTCTAGATGTTTCGTGCACCTTGTGATTTCGCAGAGACAATACACCTCCTACTCCTGC
TTCTGCAGGCGACGACTCGGGCCTGGGTTGATTGTGCGTGGAGCTGCACAGCTGTGAGCGTCCG
AGCTTTGATTGGCATTGACTCCAGAGCTGTAGCATCTCCATCCTATGCTCTGTGGCCAACGCCT
ACGCCAGCAACCTAAGAGGCTGGAGGAGGCTTGACGGAGGCCATGTAGGTGGGAGAAACCCAGA
ACTGAAGTCTTGGAATACCCTGCTTTGGACCACCAGCTCCCTTCTTGCCCTAAGCGCACTCGCT
TAGTCTGAGAGATAGGCGGTAGTGCCATTTTCTAAAATGGAGTTTAGTTGGATTTGTTTGTTTT
GGCATTTCATAAACCTGTCTCATAGCCCATCTGTTGCTTGCTGGGCCCCGAGAAGTCCCTGCTT
GTTCATACCACTGTGCCTTTGTCCATGTCAGCAAGACTCATGCCATCCCCACGCTCTGTCTCTA
GGGGTCCAGTTCTTCCCTCTGGTGTCTCCTCATTTGCAGCCCCTTGCCTTGGGGATATTCCCTG
TAGCCTGGGTTCTCAGGTTTCTACTGTCACTCAGCTTTGTGGAGCTCCTCCCACGCATCGAATT
ACTCAGTGTCAGCTCAGACCCAGAATAGGGTTAGGGCTGCTGTTCGTAGTTCGCAGATGGACAA
GCTCCTCAGTACATTCTCCTTGCAGCCGGCTGGGACACTCTGAGCCCCTTCCGGGCCCTCAGAC
ATCACCACTGCATCAAGATCCAGACTTTTCCAAAGACTGCAGGGCCTCCTCCCCTCCACACACA
GGACCAAGCCACCATGCCTGAAGTCAAAGAGCTTTCAGAAGCCTTGCCAGAGACACCAATGGAC
CCCATCACGGGAGTCGGGGTGGTAGCCTCCCGGAACCGAGCGCCGACAGGCTACGATGTGGTTG
CACAGACAGCAGATGGTGTGGACGCTGACCTCTGGAAGGACGGCTTATTCAAATCCAAGGTTAC
CAGATACCTGTGTTTCACAAGATCATTTTCTAAAGAAAACAGTCATTTGGGGAATGTGCTGGTG
GACATGAAACTCATCGACGTCAAGGACACGTTGCCTGTGGGCTTCATTCCCATCCAGGAGACGG
TGGATACACAGGAGGTGGTCTTCAGGAAGAAGAGGCTATGCATTAAGTTCATTCCCCGGGATTC
AACCGAAGCCGCCATTTGTGACATTCGCATCATGGGCCGGACCAAGCAGGCTCCTCCCCAGTAC
ACATTTATCGGGGAACTGAACAGCATGGGCATCTGGTATCGAATGGGCAGAGTGCCAAGAAACC
ATGACTCATCTCAACCCACCACGCCCTCCCAGTCATCAGCTGCTTCCACCCCAGCCCCAAACCT
TCCCAGGCACATCTCCCTGACACTCCCGGCTACCTTCCGAGGCAGAAACAACACCAGCACAGAC
TATGAGTACCAGCTCTCCAACCTGTATGCCATATCAGCAATGGACGGTGTGCCTTTTATGATTT
CAGAGAAGTTTTCCTGCATCCCAGAAAGTATGCAGCCCTTTGATCTCTTGGGAATCACCATCAA
GTCTCTGGCGGAAATTGAAAAGGAGTACGAGTACAGTTTCCGCACCGAGCAGAGCGCGGCAGCT
CGGCTCCCACCCAGCCCTACCCGGTGCCAGCAGATCCCCCAGTCCTGAGGAGCCCACAGCCTAC
CCGGTGCCCAGACTACTGATGAGGTGGCTGGGGTGAGAGTCACGCCCTCCCTCACCTGCCCATT
CTGCTTGCCCCTGCTCACTGACCAAGAGACTCTGGGCAGCTGCTTGGTCAGATACGGTCATCAG
CTCGCCTAACGAGACTTCCCTCCCTCCCCGGGAACGTTGTTCATAATTGTGACTAATGTGTGTG
CTGTTAGTGACCAGAGGCTCCTGTGTGATGACCACTTACCCCACCAAGAAAGAAAACTCCTCCC
TTACCTGGAGTCACCCATGAGGGCCTGGGCACATACTCCATCCACCCAGTGACACTCACTGGCT
ACCCTCCAACTGACCATCACTGACCACAGAAATCCCACAAAGCCACTAGCTCCCTCCTGGAAGA
CTCCAGGGTTGACTGCTTCACTTAGGACCCTGCAAGATGCACTGATGGCGTCTGACCCAGCTAC
CTGGGAACAAGCACGGCTGGCCAGCAGGCTCAAGTGGCCCAGGCATTTCATGACGGCACTGAGA
AAGCAGGCCTAAGATGCACTGGAGACAGCCGTGGGCTCTTCCCCCACTCCACACACTGGACGTC
CAGAGAGCACAGATGGGACCCTGCTTTCTGTGGAGGTGACTGGGTGCCTACCTGGATAGGAACT
TGGCTGCTAGGGTGCTGTGCCCAGCCACAGGTGCCAATCCCCACAAAGGGCTCCTCTGTGGAAC
ATCCACCTGCCAACCCCCGCTCCATATGCCTCTGCCTGGTGCCCTGCCCTGGTGGCGACTGACA
CAGAGCACGGCGCAAAGGCACCAACTCCTCACAGCCACACCCACCCCCCTGTCTAGAAGGCGCC
TTCCACCAGGGATCTGCTGTTTTGAAAAGTCCTTCTGTCCCAGACCTCTGAATTCGGGCCAGGA
CATTTCACAGGTGTCAACCTGAGGTGCCAAGTTGAACCCTACGTGTGTCGCCATGAGAACAGTG
GTCACCACTGTCCCAGCTCTCAGCCTCACCATGATGCCCTGCTTTGCCACAATTGGCTTTTAGG
GCTTGGCTGACCTTGGTTCCCCAGAGTATCTGTGGATGTGAAGATCTGCCCAGTGGTCGGTGGC
CATGGGCAACTACTCACCAGCTGGTACAAACCTCTCCCGTTACAGCTCTAGAGACAGCCACAGG
CGGCTGGGTGCCCAAGGTGCAAAAGGATCAGGAGCAAGAACAAGCCAACAGGACGGCATGAGCT
GGGGCAGGCCCCAAAATACCTCACCAACCTACATCAGCCCCTCCTGTTCCAGACCCTCAGGTCC
TTTGTAGACCACCCTTCTTCCCCAGTCAGCCAGCCTCTCTGCTTGATGGTACTTCATCTCTATG
TCAGAAGGGGTCACCTAGATGTGAGCACACCCTATGGGGTACCCATCAACCCTTGCCTCTGGGC
ACCACATTCTCCAGGTAGCACAGGTCATGACAAGGTGGTGCCCGAGACCCAACATAGGCGTCTC
CAGCAAAGCCTGATGCCACGCTGGTGCTCACAGGAGCTAACAAGCTGACCCCAGATGGCTCCAC
AAGCTGGGTATCCCAAGGACCCGTGTCTGCCACTGCTGGTGTAAAACCAAGTGGCTTGTGTGAC
CTGAGGCCCAACTAAGGGGACGACCACCCACAGTCTGAGTTACCTGGGAAGGTCAGGCACAGCG
CTCTGGACTCCCCTGACCACTTCATTTAAGTTCGTACGCTTCGACCACCTCTTTCCATCCCCCG
GTTAGGAAATCACCCCTCCCACGTGAAGCCAGGTGGCCCCCTCTTCCCCCTGCAGTCCTTGCAG
GTCCTGGAAATACGAAACTGAAGACTGTGGACCCTCATCGGTGACCCAGATGGCCAAGTGAGGG
GGTCTCCTGGAGAAAGGAGGCGCACTCTGCAGCCCACGCACGCACCCCACAGGACTCAGCCAGG
GAGGTGGGCAAAGTGTAAGCTCTGAGTTGGAGCTCTCTGAACGCTGCAGACTTAGTTGAAGAAG
AACGTTGACTGAATGTGGTAGCACCCACAGCTTCTAGCTCCCGAAGTGTTGAGGATGACTTGGT
GTCCATGGTAGGTTCTAGGTTGCACCCGACCCCTGGTCTCTTGTCTTCTGGTGATGGTAGTGGT
CGTGTGTGTGCGCGTGCCCATGTCCACCCTGTGTAAATCCAACAGACCCAGGTCTGGGAGGTAG
GGCTGTGGCTCACAGCAGCACTGAGTGGCCTCTGGGTACCATGTGGCAGGCGCACCGTGAGATG
AGCACAAGGATTCGCCGGGAGACATGAAGAGCTGTCGCCTGTCTGTGGGTCTCCTCCCCACACC
CCACCAGCATGTCCCACAACTGCTGCCAAGCACGTACATCTCTCCTGAAATGGCTAACCAGAGC
ACAGTTCCCTGTCCCCGCTATCCCCACACTGAAAAGTTGGTTCCTTCCTAAGGGCCTTGAAAAT
GGCACAAGGGTGACAAGGTGTGGTGGGGGGCGGGGGAGGGGGTGAGGGACTCCAGGTTCACTTG
CAAATGTATCATAAGACCAAACCTAAGAATTCATGTCAGCCTAACTCTCTGCCACGTGGAGAGG
TGAAAGCCTCACTCTCCTTGGGGGAAGCAGGTTAGAGCCATGACCCTTCTCCCTGGTGGTTAGC
AGCCTGTGGCCAAGGTCAGGACGTCCAGCAAGGAGACTGAGGTACTGAGCACACATACTCTCCC
TTCCACTGGGCTTGGTGGTCTTAAGCACATTTCCTGTCACCCCCCAAACAAGCCCAACAATGGG
TGCTCTTTGTCCTGTCACAAGAAGAGCCTGGGGCATAGACAGAATCTGACCCGAAGCCCCTGGG
CCAAGCACCTGGCCTCTGTGTCCACCCCTGTGGGCTTCCTTTGGCCGTGGAGATTTCATCACAC
CACGGCATGGGTTCTGGGCTTGGGTCAGGCCGATAGTCTGATTGTCCTGTGTGCCCCCCACCTA
CACCTGAGAGCTTCCCAGCCTGAGAGCATCTCTTGCTGAATTTATGGACTCCTGGCCCAGGAGC
AGGTAGAAAAGGGCCTCCATGTGCCACCGGGCCATGAAGGGCAGAATTCACAGAATTGGTTTGT
GTCCAACGGAGCCCCAGAGCCCGATAAAGAAGCTGGGCTCCCGTTCCTGTACCCAGCTCCCTCT
CAGGTGACCCCACACATCAGGGCAGCCCAGCTTTCTCCACCTGCTCTAGGCATGCGCCCTTGAG
CAACTGCGGCCACTGCACCAGGAGAGCAGGCTTTGTTCTCCTGTGAGCCGCTGGGACGAGGACC
CCAGGCACAGCTGCCTCCTGTGTATTTATTCAAGGTGACTGCTTAGCAAAGGGAGGTCTCACTG
TGTGACTGTATCTTAATATAATTTGTTAAATAAATGTTTGTTTTAACCTCGTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001258161	(Get FASTA)	NCBI Sequence Viewer
	XP_017447373	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL93181	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000023172.7
	ENSRNOP00000089240.1

RefSeq Acc Id:

NP_001258161 ⟸ NM_001271232

- UniProtKB:

D4A732 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRSCFCVRRSRDPPPPQPPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGY
DVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPI
QETVDTQEVVFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRV
PRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISAMDGVP
FMISEKFSCIPESMQPFDLLGITIKSLAEIEKEYEYSFRTEQSAAARLPPSPTRCQQIPQS

hide sequence

RefSeq Acc Id:	XP_017447373 ⟸ XM_017591884
- Peptide Label:	isoform X1
- UniProtKB:	D4A732 (UniProtKB/TrEMBL), A6JUB5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLC FTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVVFRKKRLCIKFIPRDSTEAA ICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHI SLTLPATFRGRNNTSTDYEYQLSNLYAISAMDGVPFMISEKFSCIPESMQPFDLLGITIKSLAE IEKEYEYSFRTEQSAAARLPPSPTRCQQIPQS hide sequence

Ensembl Acc Id:

ENSRNOP00000023172 ⟸ ENSRNOT00000023172

Ensembl Acc Id:

ENSRNOP00000089240 ⟸ ENSRNOT00000105862

Protein Domains

MABP UMA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A732-F1-model_v2	AlphaFold	D4A732	1-317	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692002

Promoter ID:

EPDNEW_R2527

Type:

initiation region

Name:

Mvb12b_1

Description:

multivesicular body subunit 12B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	12,944,557 - 12,944,617	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309709	AgrOrtholog
BioCyc Gene	G2FUF-50096	BioCyc
Ensembl Genes	ENSRNOG00000017172	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000023172.8	UniProtKB/TrEMBL
	ENSRNOT00000105862.1	UniProtKB/TrEMBL
Gene3D-CATH	2.100.10.50	UniProtKB/TrEMBL
InterPro	FAM125	UniProtKB/TrEMBL
	MABP	UniProtKB/TrEMBL
	MVB12B	UniProtKB/TrEMBL
	UMA	UniProtKB/TrEMBL
NCBI Gene	362118	ENTREZGENE
PANTHER	MULTIVESICULAR BODY SUBUNIT 12B	UniProtKB/TrEMBL
	PTHR31547	UniProtKB/TrEMBL
Pfam	DUF2464	UniProtKB/TrEMBL
PhenoGen	Mvb12b	PhenoGen
PROSITE	MABP	UniProtKB/TrEMBL
	UMA	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017172	RatGTEx
UniProt	A0A8I6ABB8_RAT	UniProtKB/TrEMBL
	A6JUB5	ENTREZGENE, UniProtKB/TrEMBL
	D4A732	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-12-18	Mvb12b	multivesicular body subunit 12B	Fam125b	family with sequence similarity 125, member B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Fam125b	family with sequence similarity 125, member B	RGD1309709_predicted	similar to FLJ00022 protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1309709_predicted	similar to FLJ00022 protein (predicted)	LOC362118_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC362118_predicted	similar to FLJ00022 protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)