Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PPRC1 mRNA] | CTD | PMID:31150632 | (-)-alpha-phellandrene | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of PPRC1 mRNA | CTD | PMID:25075043 | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PPRC1 mRNA | CTD | PMID:22079256 | 1,1-dichloroethene | increases expression | ISO | Pprc1 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of PPRC1 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | increases expression | ISO | Pprc1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PPRC1 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of PPRC1 mRNA | CTD | PMID:27344345 | 17alpha-ethynylestradiol | increases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of PPRC1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Pprc1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPRC1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | Estradiol promotes the reaction [ESR1 protein binds to PPRC1 protein] | CTD | PMID:23665804 more ... | 17beta-estradiol | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of PPRC1 mRNA | CTD | PMID:31614463 | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PPRC1 protein modified form] | CTD | PMID:28751236 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Pprc1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Pprc1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPRC1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PPRC1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PPRC1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PPRC1 mRNA | CTD | PMID:20159946 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of PPRC1 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PPRC1 mRNA | CTD | PMID:30851411 | 2-methylcholine | affects expression | ISO | PPRC1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of PPRC1 mRNA | CTD | PMID:21179406 | 2-palmitoylglycerol | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of PPRC1 mRNA | CTD | PMID:37199045 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | bisphenol S inhibits the reaction [ESR1 protein binds to PPRC1 protein] | CTD | PMID:29389661 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PPRC1 mRNA | CTD | PMID:30047161 | acrylamide | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of PPRC1 mRNA | CTD | PMID:32763439 | aflatoxin B1 | affects expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of PPRC1 protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of PPRC1 mRNA | CTD | PMID:22100608 | all-trans-retinoic acid | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PPRC1 mRNA | CTD | PMID:23724009 and PMID:33167477 | alpha-phellandrene | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of PPRC1 mRNA | CTD | PMID:25075043 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of PPRC1 mRNA | CTD | PMID:30047161 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of PPRC1 mRNA | CTD | PMID:30779732 | arsenous acid | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of PPRC1 mRNA | CTD | PMID:25555879 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PPRC1 mRNA | CTD | PMID:25181051 more ... | bisphenol A | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [bisphenol A binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PPRC1 protein modified form] and bisphenol A inhibits the reaction [ESR1 protein binds to PPRC1 protein] | CTD | PMID:28751236 and PMID:29389661 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of PPRC1 mRNA | CTD | PMID:19167457 | cadmium dichloride | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of PPRC1 mRNA | CTD | PMID:20883709 | caffeine | affects phosphorylation | ISO | PPRC1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of PPRC1 protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of PPRC1 mRNA | CTD | PMID:25554681 | chloropicrin | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of PPRC1 mRNA | CTD | PMID:26352163 | chlorpyrifos | affects expression | ISO | Pprc1 (Mus musculus) | 6480464 | Chlorpyrifos affects the expression of PPRC1 mRNA | CTD | PMID:37019170 | choline | multiple interactions | ISO | Pprc1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PPRC1 gene | CTD | PMID:20938992 | chromium(6+) | affects expression | ISO | Pprc1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of PPRC1 mRNA | CTD | PMID:28472532 | ciguatoxin CTX1B | affects expression | ISO | Pprc1 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of PPRC1 mRNA | CTD | PMID:18353800 | cisplatin | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of PPRC1 mRNA | CTD | PMID:27594783 | cisplatin | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of PPRC1 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of PPRC1 mRNA | CTD | PMID:19320972 | cyclosporin A | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PPRC1 mRNA | CTD | PMID:20106945 and PMID:25562108 | cyclosporin A | increases methylation | ISO | PPRC1 (Homo sapiens) | 6480464 | Cyclosporine results in increased methylation of PPRC1 promoter | CTD | PMID:27989131 | cyproterone acetate | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PPRC1 protein modified form] | CTD | PMID:28751236 | diarsenic trioxide | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [Arsenic Trioxide co-treated with Ascorbic Acid] results in increased expression of PPRC1 mRNA | CTD | PMID:25555879 | dicrotophos | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of PPRC1 mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | ISO | Pprc1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PPRC1 mRNA | CTD | PMID:30529165 | disodium selenite | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of PPRC1 mRNA | CTD | PMID:18175754 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of PPRC1 mRNA | CTD | PMID:29391264 | ethyl methanesulfonate | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of PPRC1 mRNA | CTD | PMID:23649840 | fluoranthene | multiple interactions | ISO | Pprc1 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of PPRC1 mRNA | CTD | PMID:28329830 | fluorescein 5-isothiocyanate | affects binding | ISO | PPRC1 (Homo sapiens) | 6480464 | Fluorescein-5-isothiocyanate binds to PPRC1 protein | CTD | PMID:27129696 | folic acid | multiple interactions | ISO | Pprc1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PPRC1 gene | CTD | PMID:20938992 | formaldehyde | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of PPRC1 mRNA | CTD | PMID:20655997 and PMID:23649840 | gamma-hexachlorocyclohexane | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Hexachlorocyclohexane results in increased expression of PPRC1 mRNA | CTD | PMID:23777605 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PPRC1 mRNA | CTD | PMID:22061828 and PMID:33387578 | hydrogen peroxide | affects expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of PPRC1 mRNA | CTD | PMID:20044591 | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of PPRC1 mRNA | CTD | PMID:20080153 | L-ascorbic acid | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of PPRC1 mRNA | CTD | PMID:25555879 | L-methionine | multiple interactions | ISO | Pprc1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PPRC1 gene | CTD | PMID:20938992 | menadione | affects expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of PPRC1 mRNA | CTD | PMID:20044591 | mercury atom | affects response to substance | ISO | Pprc1 (Mus musculus) | 6480464 | PPRC1 protein affects the susceptibility to Mercury | CTD | PMID:26942574 | mercury dichloride | increases expression | EXP | | 6480464 | Mercuric Chloride results in increased expression of PPRC1 mRNA | CTD | PMID:16507785 | mercury(0) | affects response to substance | ISO | Pprc1 (Mus musculus) | 6480464 | PPRC1 protein affects the susceptibility to Mercury | CTD | PMID:26942574 | methotrexate | affects response to substance | ISO | PPRC1 (Homo sapiens) | 6480464 | PPRC1 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | methyl methanesulfonate | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of PPRC1 mRNA | CTD | PMID:23649840 | monosodium L-glutamate | multiple interactions | ISO | Pprc1 (Mus musculus) | 6480464 | [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of PPRC1 mRNA | CTD | PMID:20111022 | nickel atom | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Nickel results in increased expression of PPRC1 mRNA | CTD | PMID:24768652 and PMID:25583101 | oxaloacetic acid | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Oxaloacetic Acid results in increased expression of PPRC1 mRNA and Oxaloacetic Acid results in increased expression of PPRC1 protein | CTD | PMID:26811028 | ozone | multiple interactions | ISO | Pprc1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of PPRC1 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | Pprc1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PPRC1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PPRC1 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of PPRC1 mRNA | CTD | PMID:21420995 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of PPRC1 mRNA | CTD | PMID:32680482 | pentachlorophenol | increases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of PPRC1 mRNA | CTD | PMID:23892564 | perfluorohexanesulfonic acid | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of PPRC1 mRNA | CTD | PMID:37995155 | perfluorononanoic acid | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of PPRC1 mRNA | CTD | PMID:32588087 | phenobarbital | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of PPRC1 mRNA | CTD | PMID:19482888 | phenobarbital | affects expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of PPRC1 mRNA | CTD | PMID:19159669 | pirinixic acid | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PPRC1 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of PPRC1 mRNA | CTD | PMID:17426115 | potassium chromate | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of PPRC1 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | PPRC1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PPRC1 mRNA | CTD | PMID:22079256 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of PPRC1 mRNA | CTD | PMID:28903501 | rac-lactic acid | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PPRC1 mRNA | CTD | PMID:30851411 | silicon dioxide | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of PPRC1 mRNA | CTD | PMID:25895662 | sodium arsenite | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PPRC1 mRNA | CTD | PMID:20371982 | sodium arsenite | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of PPRC1 mRNA | CTD | PMID:20883709 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of PPRC1 mRNA | CTD | PMID:25993096 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of PPRC1 mRNA | CTD | PMID:30047161 | T-2 toxin | increases expression | EXP | | 6480464 | T-2 Toxin results in increased expression of PPRC1 mRNA | CTD | PMID:29870751 | tert-butyl hydroperoxide | increases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of PPRC1 mRNA | CTD | PMID:15336504 | tetrachloromethane | increases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of PPRC1 mRNA | CTD | PMID:27339419 | tetrachloromethane | affects expression | ISO | Pprc1 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of PPRC1 mRNA | CTD | PMID:31919559 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of PPRC1 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PPRC1 mRNA] | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PPRC1 mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | increases expression | ISO | Pprc1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of PPRC1 mRNA | CTD | PMID:23409001 | titanium dioxide | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PPRC1 mRNA | CTD | PMID:23557971 | tremolite asbestos | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | tremolite results in decreased expression of PPRC1 mRNA | CTD | PMID:29279043 | trichostatin A | affects expression | ISO | PPRC1 (Homo sapiens) | 6480464 | trichostatin A affects the expression of PPRC1 mRNA | CTD | PMID:28542535 | trimellitic anhydride | decreases methylation | ISO | Pprc1 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased methylation of PPRC1 promoter | CTD | PMID:24675093 | urethane | decreases expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of PPRC1 mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | PPRC1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PPRC1 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | PPRC1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PPRC1 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of PPRC1 mRNA | CTD | PMID:19136453 and PMID:21427059 | vancomycin | decreases expression | ISO | Pprc1 (Mus musculus) | 6480464 | Vancomycin results in decreased expression of PPRC1 mRNA | CTD | PMID:18930951 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of PPRC1 mRNA | CTD | PMID:23034163 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
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