Cpsf2 (cleavage and polyadenylation specific factor 2) - Rat Genome Database

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Gene: Cpsf2 (cleavage and polyadenylation specific factor 2) Rattus norvegicus
Analyze
Symbol: Cpsf2
Name: cleavage and polyadenylation specific factor 2
RGD ID: 1309687
Description: Predicted to enable RNA binding activity. Predicted to be involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Predicted to be active in glutamatergic synapse and postsynapse. Orthologous to human CPSF2 (cleavage and polyadenylation specific factor 2); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; mRNA decay pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cleavage and polyadenylation specific factor 2, 100kDa; cleavage and polyadenylation specificity factor subunit 2; LOC299256
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86126,885,417 - 126,917,634 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6126,885,476 - 126,917,632 (+)EnsemblGRCr8
mRatBN7.26121,123,941 - 121,152,756 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6121,120,569 - 121,151,921 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6121,272,685 - 121,300,215 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06121,567,944 - 121,595,474 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06120,904,258 - 120,931,788 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06125,870,372 - 125,898,039 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6125,870,372 - 125,898,874 (+)Ensemblrn6Rnor6.0
Rnor_5.06135,081,675 - 135,110,301 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46126,246,237 - 126,274,144 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6118,620,253 - 118,647,912 (+)NCBICelera
RGSC_v3.16126,255,715 - 126,275,801 (+)NCBI
Cytogenetic Map6q32NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cylindrospermopsin  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
Dibutyl phosphate  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
flutamide  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methoxychlor  (EXP)
Monobutylphthalate  (EXP)
nickel atom  (ISO)
nitrates  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
protein binding  (ISO)
RNA binding  (IBA,IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Pre-mRNA 3'-end processing complex assembly and function. Chan S, etal., Wiley Interdiscip Rev RNA. 2011 May-Jun;2(3):321-35. doi: 10.1002/wrna.54. Epub 2010 Oct 18.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors. Gruber AR, etal., Wiley Interdiscip Rev RNA. 2014 Mar-Apr;5(2):183-96. doi: 10.1002/wrna.1206. Epub 2013 Nov 14.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:16115198   PMID:18305108   PMID:18688255   PMID:19946888   PMID:21102410  


Genomics

Comparative Map Data
Cpsf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86126,885,417 - 126,917,634 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6126,885,476 - 126,917,632 (+)EnsemblGRCr8
mRatBN7.26121,123,941 - 121,152,756 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6121,120,569 - 121,151,921 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6121,272,685 - 121,300,215 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06121,567,944 - 121,595,474 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06120,904,258 - 120,931,788 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06125,870,372 - 125,898,039 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6125,870,372 - 125,898,874 (+)Ensemblrn6Rnor6.0
Rnor_5.06135,081,675 - 135,110,301 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46126,246,237 - 126,274,144 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6118,620,253 - 118,647,912 (+)NCBICelera
RGSC_v3.16126,255,715 - 126,275,801 (+)NCBI
Cytogenetic Map6q32NCBI
CPSF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381492,121,969 - 92,172,145 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1492,121,512 - 92,172,145 (+)Ensemblhg38GRCh38
GRCh371492,588,313 - 92,638,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361491,658,082 - 91,700,296 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341491,658,081 - 91,700,296NCBI
Celera1472,640,924 - 72,683,141 (+)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1472,769,473 - 72,812,911 (+)NCBIHuRef
CHM1_11492,526,598 - 92,568,841 (+)NCBICHM1_1
T2T-CHM13v2.01486,351,804 - 86,401,990 (+)NCBIT2T-CHM13v2.0
Cpsf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912101,940,345 - 101,972,252 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12101,942,247 - 101,972,683 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3812101,975,759 - 102,005,993 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12101,975,988 - 102,006,424 (+)Ensemblmm10GRCm38
MGSCv3712103,214,184 - 103,244,203 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612102,377,049 - 102,406,579 (+)NCBIMGSCv36mm8
Celera12103,193,112 - 103,223,131 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.34NCBI
Cpsf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543814,452,943 - 14,483,199 (+)Ensembl
ChiLan1.0NW_00495543814,449,320 - 14,483,003 (+)NCBIChiLan1.0ChiLan1.0
CPSF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21593,280,808 - 93,324,771 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11492,497,318 - 92,539,769 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01472,757,419 - 72,801,149 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11492,099,278 - 92,139,902 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1492,099,301 - 92,140,470 (+)EnsemblpanPan2panpan1.1
CPSF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.181,364,399 - 1,398,496 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl81,364,353 - 1,396,255 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha81,383,120 - 1,417,297 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.081,413,268 - 1,447,465 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl81,413,270 - 1,446,270 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.181,351,164 - 1,385,354 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.081,307,513 - 1,341,912 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.081,428,458 - 1,462,658 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cpsf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864013,068,525 - 13,099,873 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936733367,109 - 397,242 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936733367,082 - 397,242 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPSF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7113,659,905 - 113,693,764 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17113,659,903 - 113,690,524 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27120,262,186 - 120,278,810 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CPSF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12469,873,056 - 69,914,129 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2469,877,446 - 69,917,541 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605357,122,042 - 57,163,431 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpsf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247348,736,911 - 8,768,583 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247348,737,023 - 8,769,088 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Cpsf2
183 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:724
Count of miRNA genes:308
Interacting mature miRNAs:406
Transcripts:ENSRNOT00000008612
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat

Markers in Region
RH131223  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26121,150,373 - 121,150,564 (+)MAPPERmRatBN7.2
Rnor_6.06125,896,492 - 125,896,682NCBIRnor6.0
Rnor_5.06135,107,919 - 135,108,109UniSTSRnor5.0
RGSC_v3.46126,272,597 - 126,272,787UniSTSRGSC3.4
Celera6118,646,365 - 118,646,555UniSTS
RH 3.4 Map6848.5UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000008612   ⟹   ENSRNOP00000008612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6126,890,015 - 126,917,632 (+)Ensembl
mRatBN7.2 Ensembl6121,124,243 - 121,151,921 (+)Ensembl
Rnor_6.0 Ensembl6125,870,372 - 125,898,039 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091300   ⟹   ENSRNOP00000075209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6126,885,476 - 126,914,661 (+)Ensembl
mRatBN7.2 Ensembl6121,120,569 - 121,151,921 (+)Ensembl
Rnor_6.0 Ensembl6125,876,109 - 125,898,874 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000149892   ⟹   ENSRNOP00000109185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6126,889,127 - 126,914,661 (+)Ensembl
RefSeq Acc Id: NM_001106753   ⟹   NP_001100223
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,889,122 - 126,916,799 (+)NCBI
mRatBN7.26121,124,243 - 121,151,921 (+)NCBI
Rnor_6.06125,870,372 - 125,898,039 (+)NCBI
Rnor_5.06135,081,675 - 135,110,301 (+)NCBI
RGSC_v3.46126,246,237 - 126,274,144 (+)RGD
Celera6118,620,253 - 118,647,912 (+)RGD
Sequence:
RefSeq Acc Id: XM_039112070   ⟹   XP_038967998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,888,820 - 126,917,634 (+)NCBI
mRatBN7.26121,123,941 - 121,152,756 (+)NCBI
RefSeq Acc Id: XM_063261763   ⟹   XP_063117833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,885,417 - 126,917,634 (+)NCBI
RefSeq Acc Id: XM_063261764   ⟹   XP_063117834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,885,417 - 126,917,634 (+)NCBI
RefSeq Acc Id: XM_063261765   ⟹   XP_063117835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,889,339 - 126,917,634 (+)NCBI
RefSeq Acc Id: NP_001100223   ⟸   NM_001106753
- UniProtKB: D3Z9E6 (UniProtKB/TrEMBL),   A6JEJ7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008612   ⟸   ENSRNOT00000008612
Ensembl Acc Id: ENSRNOP00000075209   ⟸   ENSRNOT00000091300
RefSeq Acc Id: XP_038967998   ⟸   XM_039112070
- Peptide Label: isoform X3
- UniProtKB: D3Z9E6 (UniProtKB/TrEMBL),   A6JEJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117834   ⟸   XM_063261764
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KA08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117833   ⟸   XM_063261763
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KA08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117835   ⟸   XM_063261765
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000109185   ⟸   ENSRNOT00000149892
Protein Domains
Beta-Casp

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z9E6-F1-model_v2 AlphaFold D3Z9E6 1-782 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694780
Promoter ID:EPDNEW_R5305
Type:multiple initiation site
Name:Cpsf2_1
Description:cleavage and polyadenylation specific factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06125,870,378 - 125,870,438EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309687 AgrOrtholog
BioCyc Gene G2FUF-36456 BioCyc
Ensembl Genes ENSRNOG00000005733 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008612 ENTREZGENE
  ENSRNOT00000008612.8 UniProtKB/TrEMBL
  ENSRNOT00000091300 ENTREZGENE
  ENSRNOT00000091300.3 UniProtKB/TrEMBL
  ENSRNOT00000149892 ENTREZGENE
  ENSRNOT00000149892.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.15.10 UniProtKB/TrEMBL
InterPro Beta_Casp UniProtKB/TrEMBL
  Blactmase-like UniProtKB/TrEMBL
  CPSF2 UniProtKB/TrEMBL
  Cpsf2_C UniProtKB/TrEMBL
  CPSF2_MBL UniProtKB/TrEMBL
  Metallo-hydrolase/OxRdtase UniProtKB/TrEMBL
  RMMBL UniProtKB/TrEMBL
KEGG Report rno:299256 UniProtKB/TrEMBL
NCBI Gene 299256 ENTREZGENE
PANTHER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 UniProtKB/TrEMBL
  PTHR45922 UniProtKB/TrEMBL
Pfam Beta-Casp UniProtKB/TrEMBL
  CPSF100_C UniProtKB/TrEMBL
  Lactamase_B_6 UniProtKB/TrEMBL
  RMMBL UniProtKB/TrEMBL
PhenoGen Cpsf2 PhenoGen
RatGTEx ENSRNOG00000005733 RatGTEx
SMART Beta-Casp UniProtKB/TrEMBL
Superfamily-SCOP SSF56281 UniProtKB/TrEMBL
UniProt A0A0G2KA08 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M5H2_RAT UniProtKB/TrEMBL
  A6JEJ7 ENTREZGENE, UniProtKB/TrEMBL
  D3Z9E6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Cpsf2  cleavage and polyadenylation specific factor 2  Cpsf2  cleavage and polyadenylation specific factor 2, 100kDa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-10 Cpsf2  cleavage and polyadenylation specific factor 2, 100kDa  Cpsf2  cleavage and polyadenylation specific factor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Cpsf2  cleavage and polyadenylation specific factor 2   Cpsf2_predicted  cleavage and polyadenylation specific factor 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cpsf2_predicted  cleavage and polyadenylation specific factor 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED