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Gene: Adat2 (adenosine deaminase, tRNA-specific 2) Rattus norvegicus

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Symbol:

Adat2

Name:

adenosine deaminase, tRNA-specific 2

RGD ID:

1309642

Description:

Predicted to enable tRNA-specific adenosine-34 deaminase activity. Predicted to be involved in tRNA wobble adenosine to inosine editing. Orthologous to human ADAT2 (adenosine deaminase tRNA specific 2); INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Deadc1; deaminase domain containing 1; LOC361453; tRNA-specific adenosine deaminase 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ADAT2 (adenosine deaminase tRNA specific 2)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Adat2 (adenosine deaminase, tRNA-specific 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Adat2 (adenosine deaminase tRNA specific 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ADAT2 (adenosine deaminase tRNA specific 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ADAT2 (adenosine deaminase tRNA specific 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Adat2 (adenosine deaminase tRNA specific 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ADAT2 (adenosine deaminase tRNA specific 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ADAT2 (adenosine deaminase tRNA specific 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Adat2 (adenosine deaminase tRNA specific 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Adat2 (adenosine deaminase tRNA specific 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ADAT2 (adenosine deaminase tRNA specific 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Adat2 (adenosine deaminase, tRNA-specific 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	adat2 (adenosine deaminase tRNA specific 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5292	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	JC8.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TAD2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	TAD2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	adat2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	9,774,680 - 9,795,376 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	9,774,680 - 9,795,376 (+)	Ensembl				GRCr8
mRatBN7.2	1	7,954,520 - 7,975,254 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	7,954,631 - 7,975,251 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	7,650,936 - 7,671,562 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	13,650,061 - 13,670,687 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	7,933,211 - 7,953,471 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	7,726,447 - 7,743,112 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	7,726,529 - 7,742,484 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	9,354,585 - 9,371,494 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	8,358,164 - 8,372,650 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	6,439,539 - 6,460,513 (+)	NCBI		Celera
RGSC_v3.1	1	8,358,164 - 8,372,659 (+)	NCBI
Cytogenetic Map	1	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,4'-trichlorobiphenyl (ISO)

2-hydroxypropanoic acid (ISO)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

butanal (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cobalt dichloride (ISO)

cocaine (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

DDE (ISO)

dimethyl sulfoxide (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

enzyme inhibitor (ISO)

ethyl methanesulfonate (ISO)

formaldehyde (ISO)

indole-3-methanol (EXP)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

methylparaben (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tamoxifen (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thiram (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

catalytic activity (IEA)

hydrolase activity (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Adat2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	9,774,680 - 9,795,376 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	9,774,680 - 9,795,376 (+)	Ensembl				GRCr8
mRatBN7.2	1	7,954,520 - 7,975,254 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	7,954,631 - 7,975,251 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	7,650,936 - 7,671,562 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	13,650,061 - 13,670,687 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	7,933,211 - 7,953,471 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	7,726,447 - 7,743,112 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	7,726,529 - 7,742,484 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	9,354,585 - 9,371,494 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	8,358,164 - 8,372,650 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	6,439,539 - 6,460,513 (+)	NCBI		Celera
RGSC_v3.1	1	8,358,164 - 8,372,659 (+)	NCBI
Cytogenetic Map	1	p13	NCBI

ADAT2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	143,422,832 - 143,450,695 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	143,422,832 - 143,450,695 (-)	Ensembl			hg38	GRCh38
GRCh37	6	143,743,969 - 143,771,832 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	143,785,662 - 143,813,534 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	6	144,484,388 - 144,512,268 (-)	NCBI		Celera
Cytogenetic Map	6	q24.2	NCBI
HuRef	6	141,307,848 - 141,335,729 (-)	NCBI		HuRef
CHM1_1	6	144,006,503 - 144,034,375 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	144,615,238 - 144,643,105 (-)	NCBI		T2T-CHM13v2.0

Adat2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	13,428,651 - 13,439,120 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	13,428,638 - 13,439,120 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	13,552,907 - 13,563,376 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	13,552,894 - 13,563,376 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	13,272,713 - 13,283,182 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	13,243,435 - 13,253,574 (+)	NCBI		MGSCv36	mm8
Celera	10	13,452,722 - 13,465,030 (+)	NCBI		Celera
Cytogenetic Map	10	A2	NCBI
cM Map	10	4.94	NCBI

Adat2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955436	16,955,914 - 16,979,933 (+)	Ensembl
ChiLan1.0	NW_004955436	16,956,211 - 16,978,070 (+)	NCBI	ChiLan1.0	ChiLan1.0

ADAT2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	163,405,271 - 163,433,094 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	161,300,063 - 161,327,884 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	141,201,881 - 141,226,685 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	145,923,153 - 145,947,919 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	145,923,159 - 145,947,919 (-)	Ensembl			panPan2	panpan1.1

ADAT2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	34,953,737 - 34,993,969 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	34,965,778 - 34,994,285 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	35,850,889 - 35,892,217 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	35,128,041 - 35,169,160 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	35,140,883 - 35,169,227 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	34,996,392 - 35,037,497 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	34,879,345 - 34,920,428 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	35,191,585 - 35,232,714 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Adat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	129,915,890 - 129,940,926 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936625	2,694,754 - 2,719,792 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936625	2,694,748 - 2,717,958 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADAT2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	21,801,560 - 21,824,434 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	21,801,565 - 21,831,268 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	24,188,803 - 24,210,658 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADAT2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	29,792,337 - 29,815,537 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666040	1,926,955 - 1,951,934 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adat2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624753	10,826,297 - 10,846,199 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624753	10,826,342 - 10,846,199 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Adat2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	223,610,697 - 223,629,274 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Adat2
174 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	175
Count of miRNA genes:	126
Interacting mature miRNAs:	143
Transcripts:	ENSRNOT00000073460
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313090	Bmd69	Bone mineral density QTL 69	4.4	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	5293229	34184556	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	7746118	52746118	Rat
4889451	Eae29	Experimental allergic encephalomyelitis QTL 29	5.51		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	7746121	52746121	Rat
70179	Xhs2	X-ray hypersensitivity QTL 2	3.2		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	1	1	43965634	Rat
1354647	Despr8	Despair related QTL 8		0.0000341	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	1	26564886	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	6941022	51941022	Rat
2313070	Bss52	Bone structure and strength QTL 52	4.4	0.0001	body length (VT:0001256)	body length (CMO:0000013)	1	5293229	34184556	Rat
1357401	Bw43	Body weight QTL 43	3.75		body mass (VT:0001259)	body weight (CMO:0000012)	1	6909353	51909353	Rat
1600360	Mcs16	Mammary carcinoma susceptibility QTL 16	2.4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	1	26564886	Rat
5684998	Bss101	Bone structure and strength QTL 101	3.6		tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	1	6909353	51909353	Rat
5684999	Bss102	Bone structure and strength QTL 102	5.5	7e-07	tibia strength trait (VT:1000284)	tibia stiffness (CMO:0001735)	1	6909353	51909353	Rat
2317755	Glom22	Glomerulus QTL 22	3.8		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	1	34184556	Rat
1300170	Rf6	Renal function QTL 6	3.14		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	1	1	28483164	Rat
2313053	Bss51	Bone structure and strength QTL 51	3.8	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	5293229	34184556	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001115028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010054014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010054015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC158616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000073460 ⟹ ENSRNOP00000066415

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	9,774,680 - 9,795,376 (+)	Ensembl
mRatBN7.2 Ensembl	1	7,954,631 - 7,975,251 (+)	Ensembl
Rnor_6.0 Ensembl	1	7,726,529 - 7,742,484 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096359 ⟹ ENSRNOP00000095806

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	7,954,631 - 7,975,251 (+)	Ensembl

RefSeq Acc Id:

NM_001115028 ⟹ NP_001108500

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	9,774,680 - 9,795,376 (+)	NCBI
mRatBN7.2	1	7,954,549 - 7,975,254 (+)	NCBI
Rnor_6.0	1	7,726,447 - 7,743,112 (+)	NCBI
Rnor_5.0	1	9,354,585 - 9,371,494 (+)	NCBI
RGSC_v3.4	1	8,358,164 - 8,372,650 (+)	RGD
Celera	1	6,439,539 - 6,460,513 (+)	RGD

Sequence:

show sequence

GGAAGCAAGGGCCCGCGCCCGCCGCGTTCCGCTGTCCTCTTTCCTCCAGTCCCTTGGCCCGGAG
TCTCTGAGAGAAGGCGATATGGAAGAGAAAGTGGAGTCCACCACTGTTCCAGACGGCTCGTGCG
TGGTGTCCGTACAGGAGACCGAAAAGTGGATGGAGGAGGCGATGCGAATGGCCAAAGAAGCACT
CGAGAATATTGAAGTTCCTGTCGGCTGCCTCATGGTCTATAACAATGAAGTTGTGGGGAAGGGA
AGAAATGAAGTGAATCAAACAAAAAACGCTACTCGGCATGCTGAAATGGTGGCCATCGATCAGG
TCCTGGATTGGTGTCATCGACATGGACAGAGCCCTTCGGCGGTATTCGAACACACGGTGTTGTA
CGTCACTGTGGAGCCGTGCATCATGTGTGCCGCTGCCCTGCGCCTCATGAAAATCCCGCTGGTC
GTCTATGGCTGTCAGAATGAACGGTTTGGTGGTTGTGGTTCTGTCCTAAACATTGCCTCTGCTG
ACCTACCCAATACTGGGAGACCATTTCAGTGCATCCCCGGGTACCGTGCTGAGGAGGCCGTGGA
GCTCCTAAAGACCTTTTACAAACAGGAAAACCCAAATGCACCAAAATCAAAAGTTCGGAAAAAG
GATTGTCAGAAATCCTGATGCTGTAGTGATCAAGGACTAGTGTTGGAGACCTGGACAGAATTCC
GGCCTGAATGCTGCTGGCATCACTGGTCACGTTTACATGTTATTACTGTGTGTGAAAATGGTGT
CTCTCATCATTTGCTCTGTTAAGGGAACAAATTAGCCCTTTTTTAAAAGTCTGTAAACAACTAT
TAGCTCTTCCACCAAGCTGAAAGAATGTTTCCAGGAAGGGGAGGGATTAAAGTTTGAGATCAGC
AAGCAGTGCCTGCCCTTGACCCACAGCCTTAGCCCCAGCTTCATGAAGCTCTTTGTGGCTGTGG
AGATGGCCAAGTGGTTGCCATGCAGCCACGAGGACTGGGTCCCCAACAATGCCAGGTGGACTTG
GTGGCCTGCCTGTAATTCCAGTACTTGGAAATCCCAGGGCTCCCGAAATCCCAAAGCAAGCTAA
CTAATTAGATTAGCCCTTACCGGTGAGCTCTGTGGTCAAATGAGAGATGCTGCCTCAATAATAA
CGTGAAGGGTGATCTCGGAGGAACCCTGGTGTCAACCTTAGGCGTCACATGTCCACACGCTCCT
CATCTCCCAACCCAAATGTAAGTCTGACACATCATCGGGAGATTGATCAAGCTCAAAACAGGAA
ATAGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039081076 ⟹ XP_038937004

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	9,774,732 - 9,795,376 (+)	NCBI
mRatBN7.2	1	7,954,520 - 7,975,254 (+)	NCBI

RefSeq Acc Id:

XM_039081082 ⟹ XP_038937010

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	9,777,235 - 9,795,376 (+)	NCBI
mRatBN7.2	1	7,957,631 - 7,975,254 (+)	NCBI

RefSeq Acc Id:

XM_039081088 ⟹ XP_038937016

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	9,777,231 - 9,795,376 (+)	NCBI
mRatBN7.2	1	7,957,102 - 7,975,254 (+)	NCBI

RefSeq Acc Id:

XM_063265979 ⟹ XP_063122049

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	9,774,732 - 9,795,376 (+)	NCBI

RefSeq Acc Id:

XR_010054014

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	9,774,732 - 9,792,553 (+)	NCBI

RefSeq Acc Id:

XR_010054015

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	9,774,732 - 9,792,569 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001108500	(Get FASTA)	NCBI Sequence Viewer
	XP_038937004	(Get FASTA)	NCBI Sequence Viewer
	XP_038937010	(Get FASTA)	NCBI Sequence Viewer
	XP_038937016	(Get FASTA)	NCBI Sequence Viewer
	XP_063122049	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI58617	(Get FASTA)	NCBI Sequence Viewer
	EDL93734	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000066415.3

RefSeq Acc Id:	NP_001108500 ⟸ NM_001115028
- UniProtKB:	B0BMY9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEEKVESTTVPDGSCVVSVQETEKWMEEAMRMAKEALENIEVPVGCLMVYNNEVVGKGRNEVNQ TKNATRHAEMVAIDQVLDWCHRHGQSPSAVFEHTVLYVTVEPCIMCAAALRLMKIPLVVYGCQN ERFGGCGSVLNIASADLPNTGRPFQCIPGYRAEEAVELLKTFYKQENPNAPKSKVRKKDCQKS hide sequence

Ensembl Acc Id:

ENSRNOP00000066415 ⟸ ENSRNOT00000073460

RefSeq Acc Id:	XP_038937004 ⟸ XM_039081076
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038937016 ⟸ XM_039081088
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038937010 ⟸ XM_039081082
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000095806 ⟸ ENSRNOT00000096359

RefSeq Acc Id:	XP_063122049 ⟸ XM_063265979
- Peptide Label:	isoform X2

Protein Domains

CMP/dCMP-type deaminase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0RA73-F1-model_v2	AlphaFold	M0RA73	1-188	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689497

Promoter ID:

EPDNEW_R22

Type:

initiation region

Name:

Adat2_1

Description:

adenosine deaminase, tRNA-specific 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	7,726,483 - 7,726,543	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309642	AgrOrtholog
BioCyc Gene	G2FUF-62359	BioCyc
Ensembl Genes	ENSRNOG00000046983	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000073460.4	UniProtKB/TrEMBL
Gene3D-CATH	Cytidine Deaminase, domain 2	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7388507	IMAGE-MGC_LOAD
InterPro	APOBEC/CMP_deaminase_Zn-bd	UniProtKB/TrEMBL
	CMP_dCMP_Zn-bd	UniProtKB/TrEMBL
	Cytidine_deaminase-like	UniProtKB/TrEMBL
	tRNA_aden_deaminase	UniProtKB/TrEMBL
KEGG Report	rno:361453	UniProtKB/TrEMBL
MGC_CLONE	MGC:187499	IMAGE-MGC_LOAD
NCBI Gene	361453	ENTREZGENE
PANTHER	CYTOSINE DEAMINASE FAMILY MEMBER	UniProtKB/TrEMBL
	TRNA-SPECIFIC ADENOSINE DEAMINASE 2	UniProtKB/TrEMBL
Pfam	dCMP_cyt_deam_1	UniProtKB/TrEMBL
	MafB19-deam	UniProtKB/TrEMBL
PhenoGen	Adat2	PhenoGen
PROSITE	CYT_DCMP_DEAMINASES	UniProtKB/TrEMBL
	CYT_DCMP_DEAMINASES_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000046983	RatGTEx
Superfamily-SCOP	Cytidine_deaminase-like	UniProtKB/TrEMBL
UniProt	B0BMY9	ENTREZGENE, UniProtKB/TrEMBL
	M0RA73_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-07-16	Adat2	adenosine deaminase, tRNA-specific 2	Deadc1	deaminase domain containing 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Deadc1	deaminase domain containing 1	Deadc1_predicted	deaminase domain containing 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Deadc1_predicted	deaminase domain containing 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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