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Gene: Fam193a (family with sequence similarity 193, member A) Rattus norvegicus

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Symbol:

Fam193a

Name:

family with sequence similarity 193, member A

RGD ID:

1309634

Description:

Orthologous to human FAM193A (family with sequence similarity 193 member A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical LOC305452; LOC103690085; LOC305452; protein FAM193A-like; RGD1309634; uncharacterized protein LOC305452

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	80,480,742 - 80,607,086 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	80,480,742 - 80,607,024 (-)	Ensembl				GRCr8
mRatBN7.2	14	76,250,103 - 76,382,525 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	76,256,161 - 76,382,514 (-)	Ensembl				mRatBN7.2
Rnor_6.0	14	81,515,897 - 81,638,919 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	81,516,407 - 81,638,934 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	82,203,381 - 82,326,333 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	14	82,583,510 - 82,593,446 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	81,898,783 - 81,981,572 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	75,180,670 - 75,306,206 (-)	NCBI		Celera
RGSC_v3.1	14	81,901,167 - 81,955,170 (-)	NCBI
Cytogenetic Map	14	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

alpha-pinene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

chloroprene (EXP)

cisplatin (ISO)

clobetasol (ISO)

coumarin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

DDE (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

fenvalerate (EXP)

formaldehyde (ISO)

FR900359 (ISO)

gentamycin (EXP)

glycidol (EXP)

hydrogen cyanide (ISO)

leflunomide (ISO)

methamphetamine (ISO)

methidathion (ISO)

methyl methanesulfonate (ISO)

nitrofen (EXP)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

potassium cyanide (ISO)

quercetin (ISO)

sodium arsenate (ISO)

thapsigargin (ISO)

titanium dioxide (ISO)

topotecan (EXP)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of signal transduction by p53 class mediator (ISO)

Cellular Component

cytoplasm (ISO)

nucleus (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Fam193a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	80,480,742 - 80,607,086 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	80,480,742 - 80,607,024 (-)	Ensembl				GRCr8
mRatBN7.2	14	76,250,103 - 76,382,525 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	76,256,161 - 76,382,514 (-)	Ensembl				mRatBN7.2
Rnor_6.0	14	81,515,897 - 81,638,919 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	81,516,407 - 81,638,934 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	82,203,381 - 82,326,333 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	14	82,583,510 - 82,593,446 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	81,898,783 - 81,981,572 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	75,180,670 - 75,306,206 (-)	NCBI		Celera
RGSC_v3.1	14	81,901,167 - 81,955,170 (-)	NCBI
Cytogenetic Map	14	q21	NCBI

FAM193A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	2,535,375 - 2,732,573 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	2,536,646 - 2,732,573 (+)	Ensembl			hg38	GRCh38
GRCh37	4	2,537,102 - 2,734,300 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	2,596,957 - 2,704,100 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	4	2,664,364 - 2,771,507	NCBI
Celera	4	2,538,459 - 2,645,603 (+)	NCBI		Celera
Cytogenetic Map	4	p16.3	NCBI
HuRef	4	2,566,408 - 2,673,398 (+)	NCBI		HuRef
CHM1_1	4	2,625,112 - 2,732,275 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	2,534,120 - 2,731,332 (+)	NCBI		T2T-CHM13v2.0

Fam193a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	34,527,295 - 34,643,800 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	34,527,277 - 34,643,800 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	34,369,933 - 34,486,458 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	34,369,933 - 34,486,456 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	34,763,500 - 34,829,105 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	34,737,708 - 34,803,313 (+)	NCBI		MGSCv36	mm8
Celera	5	31,891,761 - 31,957,359 (+)	NCBI		Celera
Cytogenetic Map	5	B2	NCBI
cM Map	5	17.88	NCBI

Fam193a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955514	1,588,894 - 1,672,292 (+)	Ensembl
ChiLan1.0	NW_004955514	1,588,882 - 1,672,292 (+)	NCBI	ChiLan1.0	ChiLan1.0

FAM193A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	2,871,773 - 3,068,236 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	2,806,017 - 3,004,143 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	2,678,935 - 2,875,203 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	2,584,369 - 2,777,767 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	2,641,979 - 2,777,761 (+)	Ensembl			panPan2	panpan1.1

FAM193A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	61,543,738 - 61,674,729 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	61,544,354 - 61,644,322 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	64,126,947 - 64,291,419 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	62,019,542 - 62,184,441 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	62,019,542 - 62,089,617 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	61,510,589 - 61,675,269 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	61,715,556 - 61,880,952 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	62,075,411 - 62,240,712 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fam193a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	67,173,199 - 67,262,618 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936477	20,871,241 - 20,964,352 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936477	20,874,889 - 20,964,328 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FAM193A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	1,388,266 - 1,523,928 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	8	1,388,442 - 1,523,935 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	1,022,753 - 1,106,802 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FAM193A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	46,028,534 - 46,227,991 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	46,028,533 - 46,168,051 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666051	2,392,353 - 2,530,379 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fam193a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624755	24,996,270 - 25,133,961 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624755	24,996,262 - 25,133,918 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Fam193a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	70,582,380 - 70,696,053 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Fam193a
654 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	162
Count of miRNA genes:	126
Interacting mature miRNAs:	146
Transcripts:	ENSRNOT00000018616
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313089	Bss81	Bone structure and strength QTL 81	3.4	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	14	38023710	83023710	Rat
9590294	Uminl4	Urine mineral level QTL 4	5.66	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	14	59848686	104848686	Rat
1582236	Gluco22	Glucose level QTL 22	3.3	0.0164	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	96755654	Rat
2300197	Scl59	Serum cholesterol level QTL 59			blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	77914838	104348525	Rat
70214	Niddm28	Non-insulin dependent diabetes mellitus QTL 28	4.06		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	39009444	84009444	Rat
70153	Bp59	Blood pressure QTL 59	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	14	72970210	87582095	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30674469	85041098	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	33424686	102238540	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	74255551	109089856	Rat
1582197	Gluco27	Glucose level QTL 27	3.4	0.0006	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	77640071	96755654	Rat
2313100	Bss82	Bone structure and strength QTL 82	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	14	38023710	83023710	Rat
634328	Hc5	Hypercalciuria QTL 5	2.3		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	14	62398852	107398852	Rat
1582250	Gluco26	Glucose level QTL 26	3.3	0.0009	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	100078267	Rat
2317879	Alcrsp27	Alcohol response QTL 27	3.3	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	14	60854936	105854936	Rat
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	74255551	109089856	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	100078267	Rat
1582255	Gluco29	Glucose level QTL 29	3.1	0.0025	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	14	77640071	96755654	Rat
9589034	Epfw11	Epididymal fat weight QTL 11	6	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	14	59848686	104848686	Rat
1582209	Gluco20	Glucose level QTL 20	3.8	0.0005	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	96755654	Rat
2313048	Bss84	Bone structure and strength QTL 84	3.1	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	14	38023710	83023710	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42616258	99224555	Rat
1549834	Scl45	Serum cholesterol level QTL 45	5.8		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	65920283	99224555	Rat
738037	Hcas6	Hepatocarcinoma susceptibility QTL 6	2.93		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	14	39411170	87582095	Rat
2313084	Bss83	Bone structure and strength QTL 83	2.9	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	14	38023710	83023710	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001427458	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_002724985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_223536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018616 ⟹ ENSRNOP00000018616

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	80,480,742 - 80,607,024 (-)	Ensembl
mRatBN7.2 Ensembl	14	76,256,161 - 76,382,514 (-)	Ensembl
Rnor_6.0 Ensembl	14	81,516,407 - 81,638,934 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097212 ⟹ ENSRNOP00000095571

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	80,480,742 - 80,606,966 (-)	Ensembl
mRatBN7.2 Ensembl	14	76,256,161 - 76,382,514 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115786 ⟹ ENSRNOP00000084188

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	80,480,742 - 80,607,024 (-)	Ensembl
mRatBN7.2 Ensembl	14	76,256,161 - 76,382,514 (-)	Ensembl

RefSeq Acc Id:

NM_001427458 ⟹ NP_001414387

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	80,480,742 - 80,607,024 (-)	NCBI

RefSeq Acc Id:

XM_039092826 ⟹ XP_038948754

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	80,504,468 - 80,607,086 (-)	NCBI
mRatBN7.2	14	76,279,884 - 76,382,525 (-)	NCBI

RefSeq Acc Id:

XM_063273154 ⟹ XP_063129224

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	80,480,742 - 80,607,072 (-)	NCBI

RefSeq Acc Id:

XM_223536 ⟹ XP_223536

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	80,480,742 - 80,606,471 (-)	NCBI
mRatBN7.2	14	76,250,103 - 76,381,901 (-)	NCBI
Rnor_6.0	14	81,515,897 - 81,638,919 (-)	NCBI
Rnor_5.0	14	82,203,381 - 82,326,333 (-)	NCBI
RGSC_v3.4	14	81,898,783 - 81,981,572 (-)	RGD

Sequence:

show sequence

AGTGCCCCCTAGAAGTTTCTGGGTACCGCTGGCGTGCCACGGGCGCGGTTGTCTTGCCCTCTGT
GCCTGCTGCTGTAGGCTCTCGGGAGCCGCCGGGGGTCTCTTTCCTCTGGAGTGTCAGCTGAGTA
TAGTCTCAAGGGTTGGGGTAACTATTTTTTCAGGTTTACTTACGCAGGCATGCCGACGATGGAC
TGCTGTCGCTTTTATTCTGCTTCAGAAGATAGTGCTGACTCCTTTTAGTTTTGGCATGAATCAT
AGGACACCACCCTACCCCGCTGGGGATTATTGTCTTCTATGCAGAAGTGAACGGAAAGACTCTT
CATTCTTAGAGAGTGGAGTTAAGACTGCGAGCAAATTGGCCCTTTCCATGGCTCCCAAGGGCAA
CAGCGTGCTGCACCTGCCGCTGTGGGTATGCCCAGACTGCCGGAGGACTGTGGAGAAGGAAGAG
AGGCACAGCGGTCTTGACCAGCCGGGCCAAGATTTTCTCCTTCACTCATCACTTGGGGGTTCCC
AGCCAGAGACCAGTGGTGCTGGGAGGCTGGCCCTAGGCACACAGACCATGACCTCATCAGGGCT
AGGCACCACACCCTCAGATGCCTGTTCATGTGAGGCCTGCAGTGAACGCAGAGACATCTCAGCA
GAGACAGACCGGGAACCACAGCAACTGCAAAACTATTGGTCAGAAGTACGCTACATGGTCCGAT
GCATATACCGCCAGGCAGGGACCCCGCTGGCAGAAGACCAGGACCAGTCTCTGGTTCCCGACAA
AGAGGGAGTAAAGGAGCTCGTGGATAGGCTCTGTGAGCGGGATCCCTATCAGCTCTACCAGAGG
TTGGAGCAACAAGCCCGGGAATATGTGCTAGAAATGAAGGTTCGTCTGCTCCGGCAGCTGTCTG
CTGCAGCAAAGGCCAAGGCACCATCCGGCTTGCAAGGCCCACCACAAGCACACCACTTTGTCTC
CCTACTCCTGGAAGAGTATGGTGCCCTCTGTCAGGCTGCACGATCCATCAGTACCTTTCTTGGC
ACTCTGGAAAATGAACATTTGAAAAAGTTCCAGGTGACATGGGAACTGCATAACAAACATCTGT
TTGAAAATCTGGTCTTTTCAGAGCCACTACTCCAGAGCAACTTGCCAGCACTGGTGTCTCAGAT
CAGGCTAGGAACCACTACACATGACACCTGCAATGAAGACATGTACAGCACCTTGCTGCAGAGG
TACCAGCGCTCTGAGGAAGAGTTGCGTAAAGTTGCTGAGGAGTGGCTGGAGTGTCAGAAGAGGA
TCGATGCCTATGTGGATGAGCAGATGACAATGAAAACCAAACAGCGCATGTTGACAGAAGACTG
GGAGATTTTTAAGCAAAGGAGATTAATTGAAGAGCAGTTAACTAATAAGAAAGTGGTTACTGGC
GAGAACAACTTCACAGATACCAGGAGGCACATGTTGTCATCTCGGTTGAGCATGCCGGACTGCC
CCAACTGCAACTACAGGCGAAGATGTGCTTGTGATGACTGCAGCCTCTCACACATCCTCACTTG
TGGTATCATGGACACCCCCGTCACTGATGACATCCACATTCACCAGCTACCACTCCAAGTGGAT
TCTGCTCCCGACTATCTGTCTGAGATGCGCCCACCTAGTGTGTCATCAGCAAGCTCAGGGTCAG
GTTCCAGCTCTCCCATCACAATTCAGCAACATCCCAGACTCATCCTCACAGACAATGGCTCTGC
ACCAACTTTTTGTAGTGATGATGAAGATGTCGCACCATTGTCAGCTAAGTTTGCTGACATTTAT
CCGTTGACCAACTATGATGATACCAATGTGGTGGCCAACATGAATGGAATCCACAGCGAACTGA
ATGGTGGTGGGGAAAACATGGCCCTGAAAGATGAGTCCCCTCAGGTAAGCAGCACCAGCCGTAG
TTCTTCAGAAGCTGATGATGAAGAAGCTGATGCTGAGAGTAGTGGTGAGCCCCCAGGAGCTCCC
AAACAAGAGGAGGCCATAGGGAATGGTAACCCCAGGACAGAGGAGAGTAAAGTGAACACTCCAC
CTCCATCCTACCCAGCTCAGCAGGCAGAACAAACACCAAACACTTGTGAATGCCACGTTTGTAA
ACAAGAAGCTTCTGGGCTACCAGCATCAGCAATGACTGCTGGAGCCCTGCCTCCTGGCCATCAG
TTCCTGAGCCCAGAAAAACCAACACATCCTGCGCTTCACCTGTACCCCCACATCCACGGACATG
TGCCCTTGCATACTGTTCCACACTTGCCACGACCGCTCATCCATCCCACCTTGTATCCAGCACC
CCCCTTCACACACAGTAAGGCTTTACCGCCAGCACCTGTTCAGAGTCACACAAATAAGCCTCAG
GCATTCAATGCATCTCTTCAAGACCATATTTACCCGAGCTGTTTTGGGAACACTCCAGACTGGA
ATAGTTCTAAATTTATAAGTCTTTGGGAATCAGAAATGATGAATGATAAGAACTGGAACCCTGG
CACTTTCTTGCCAGATACAATTTCTGGAAGTGATATATTAGGGCCAGTGCTCTCAGAAACAAGA
CCTGAAGCCCTTCCACCTCCACCCAGCAATGAGGCTCCTGCAGTTTCAGATATCAAAGAAAAGA
AAAATGCTGCAAAAAAGAAGTGTTTGTATAATTTCCAAGATGCTTTTATGGAAGCAAATGAAGT
TGCCATGGCAAACACAGTTGCCATGGCTACCTCCTCAGCCACATCCTCTGTGTCATGCACAGCC
ACCACGGTGCAGTCTAGCAGCAGTCAGTTCAAGGTGTCATCCAGAAGGCCGCCTTCCATAGGTG
ATGTTTTTCATGGCCTCAACAAGGAAGATCACAGACATTCAGCACCTGCTGCTCCAAGGAACAG
CCCCACAGGCCTAGCCCCACTCCCAGCCTTGTCTCCTTCTGCGCTCTCTCCAGCCTCCACACCT
CACCTTCCAAACCTTGCTGCCCCATCATTCCCCAAAACTGCAACCACAGCCCCTGGGTTCGTGG
ATACACGCAAGAGCTTCTGTCCTACCCCTGTGGCACCCCCACCCTCCACAACAGATGGCTCCAT
AAGTGCCCCTCCCAGTGTCTGCAGTGACCCTGACTGTGAAGGGCACCGCTGCGAGAATGGTGTG
TATGACCCGCAGCAGGATGATGGGGATGAGAGTGCAGATGAGGACAGCTGCTCTGAGCACAGCT
CTAGCACCTCAACTTCCACCAACCAGAAGGAGGGCAAGTACTGTGACTGCTGCTACTGTGAGTT
CTTTGGACATGGCGGGCCTCCAGCTGCACCAACAAGTAGAAATTATGCAGAAATGAGGGAAAAG
CTTCGTTTACGGCTGACTAAGAGGAAGGAAGAACAACCCAAGAAAATGGAGCAGATCTCAGAAC
GGGAGGGTGTTGTTGACCATCGGAGAGTGGAGGATTTGTTACAGTTTATAAACAGCTCAGAGGC
CAAGCCAGTTAGTAGTAGTCGGGCAGCCAAACGAGCGAGACACAAGCAGAGGAAGCTGGAAGAG
AAGGCACGCCTAGAAGCTGAGGCCAGGGCACGGGAGCATCTGCATCATCAGGAGGAGCAAAAGC
AGCGGGAGGAGGAGGAGGAAGAAGAGGAGGAGGATGAGGAACAGCGTTTCAAGGAGGAATTTCA
GCGGCTTCAGGAGCTTCAGAAGTTAAGAGCTGCAAAAAAGAAGAAAAAGGATCGGCCAAGTAAA
GACTGTTCCAAGTTGGACATGCTTGCTAGAAATTTCCAGGCAGCAACAGAGCCTATCTCTAACT
CTGAAAACATCCACAATGGCTCATTAGAACAAACCGAAGAACCAGAAACCTCATCTCACTCCCC
TTCCAGACACATGAACCACTCAGAGCCCAGGCCAGGCCCTGGAGCCAATGGGGATGCTACAGAC
CCTGTGGACCCCAGAGACTCCAAGCTTCTGCTACCCAAGGAAGTCAATGGGAAGCAGCACGAGC
CTCTTGCATTTCTCTTGGACATGATGCATCATCACAAAGAGGGAAATAGCAAGCAGAAGTTAAA
GCAAACCAGCAAGGCCAGCAGTGAGCCAGCCAGGAAGCCCACAGAACCTCCTAAAACCACAGAG
GTACAGCTCAAACCCCGGGCCCAGCCAGAGTTGAAGCCTAAAGTAGTTGACCTTGCTCTCCTCA
CAGAGCAGAAGAGGGAGGAGAGGAAAACCAACAGCAACAACAACAACAAAAAGCAGCTGAGCCA
CATCAAAGAGGAGAAGCTGAGCACTGTCACTCCTGAGCCACCCTCCCCCAGCCAGCACCTGCAG
AATGGCAGGCTGATTCTGGCCAGTTCTCCTCAGCCCAAAGGCAAGAATAAGAAAAATAAAAAGA
AGAAAGGAGACAGAACCAGCAGTTCAATTGATGATGTTTTTCTGCCTAAAGACATCGACCTGGA
CAATGTGGATATGGATGAGACCGAGCGGGAGGTGGAGTATTTCAAAAGGTTTTGCTTGGACTCT
GCTAGACAGAACCGACAAAGACTGTCCATCAACTGGTCCAACTTTAGCTTGAAGAAGGCCACCT
TTGCTGCCCACTGAATGAGGACTGCCTGGAGAGGGATATGTGGGAGGCAGCTGGGCTGCGCCAC
TCAAGAGCCAAGCCCCTCACTGGCTCCCCTGAGCTTCAGTACCCACCCAGGGTGTGTAGGGCGG
GATGCTGTGGCCTGATACCCCCAGATTGAGAACTTGCTGCTCGACCTGCGTTGTTAGCTTGTGT
GCGTGTAGTCTGTGAGTGAGACTTCTTTGATTGTAGCTCTGTGCTGTCGGAATGGAACAGTAGT
TCCCGCCAATTTCTCCACCACCACGGCTTCAGAGGCCTGGGCCGTGGCCAGAGACGAGTTTGCA
TCATCCACGTGGCTCTGTTGCCTCTGCATCTCGCCCTGTCCTGTCATCTGTCCCCGCCAGGGTG
TCAGTCATCCCTCAGCTCCCATGTGCCCTGTGTCCCACCCAAGGCGGGCTGGGCGGGCAGGCCT
CCTTTGTCCTCTTTCACAATCTACTGTTTCTGAGTGTACACGTTGCGCTGTTTGTGTTTGACCC
CCTGACTTGTAGCCAGCTTGTGTAAGACCCCTTGCAGAATGAGAACGTTAAAAACAAGAAACCC
ACCCAGTACTCACACCATCAAGTCTGTTCTAGAGCGTACAACCGTATTAACACGGAGGCCTGCC
TGGCTACTTTTTTAACATATTGTTAAGTAATATTAAAATCATGTCTTTCTTTTTGAAAGATGGA
ATACATTAGTACAGCAGGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001414387	(Get FASTA)	NCBI Sequence Viewer
	XP_038948754	(Get FASTA)	NCBI Sequence Viewer
	XP_063129224	(Get FASTA)	NCBI Sequence Viewer
	XP_223536	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM00095	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018616.8
	ENSRNOP00000084188
	ENSRNOP00000084188.1
	ENSRNOP00000095571
	ENSRNOP00000095571.1

RefSeq Acc Id:	XP_223536 ⟸ XM_223536
- Peptide Label:	isoform X1
- UniProtKB:	D3ZIG8 (UniProtKB/TrEMBL), A6IK31 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNHRTPPYPAGDYCLLCRSERKDSSFLESGVKTASKLALSMAPKGNSVLHLPLWVCPDCRRTVE KEERHSGLDQPGQDFLLHSSLGGSQPETSGAGRLALGTQTMTSSGLGTTPSDACSCEACSERRD ISAETDREPQQLQNYWSEVRYMVRCIYRQAGTPLAEDQDQSLVPDKEGVKELVDRLCERDPYQL YQRLEQQAREYVLEMKVRLLRQLSAAAKAKAPSGLQGPPQAHHFVSLLLEEYGALCQAARSIST FLGTLENEHLKKFQVTWELHNKHLFENLVFSEPLLQSNLPALVSQIRLGTTTHDTCNEDMYSTL LQRYQRSEEELRKVAEEWLECQKRIDAYVDEQMTMKTKQRMLTEDWEIFKQRRLIEEQLTNKKV VTGENNFTDTRRHMLSSRLSMPDCPNCNYRRRCACDDCSLSHILTCGIMDTPVTDDIHIHQLPL QVDSAPDYLSEMRPPSVSSASSGSGSSSPITIQQHPRLILTDNGSAPTFCSDDEDVAPLSAKFA DIYPLTNYDDTNVVANMNGIHSELNGGGENMALKDESPQVSSTSRSSSEADDEEADAESSGEPP GAPKQEEAIGNGNPRTEESKVNTPPPSYPAQQAEQTPNTCECHVCKQEASGLPASAMTAGALPP GHQFLSPEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYPAPPFTHSKALPPAPVQSHTN KPQAFNASLQDHIYPSCFGNTPDWNSSKFISLWESEMMNDKNWNPGTFLPDTISGSDILGPVLS ETRPEALPPPPSNEAPAVSDIKEKKNAAKKKCLYNFQDAFMEANEVAMANTVAMATSSATSSVS CTATTVQSSSSQFKVSSRRPPSIGDVFHGLNKEDHRHSAPAAPRNSPTGLAPLPALSPSALSPA STPHLPNLAAPSFPKTATTAPGFVDTRKSFCPTPVAPPPSTTDGSISAPPSVCSDPDCEGHRCE NGVYDPQQDDGDESADEDSCSEHSSSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEM REKLRLRLTKRKEEQPKKMEQISEREGVVDHRRVEDLLQFINSSEAKPVSSSRAAKRARHKQRK LEEKARLEAEARAREHLHHQEEQKQREEEEEEEEEDEEQRFKEEFQRLQELQKLRAAKKKKKDR PSKDCSKLDMLARNFQAATEPISNSENIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGPGANGD ATDPVDPRDSKLLLPKEVNGKQHEPLAFLLDMMHHHKEGNSKQKLKQTSKASSEPARKPTEPPK TTEVQLKPRAQPELKPKVVDLALLTEQKREERKTNSNNNNKKQLSHIKEEKLSTVTPEPPSPSQ HLQNGRLILASSPQPKGKNKKNKKKKGDRTSSSIDDVFLPKDIDLDNVDMDETEREVEYFKRFC LDSARQNRQRLSINWSNFSLKKATFAAH hide sequence

Ensembl Acc Id:

ENSRNOP00000018616 ⟸ ENSRNOT00000018616

RefSeq Acc Id:	XP_038948754 ⟸ XM_039092826
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000095571 ⟸ ENSRNOT00000097212

Ensembl Acc Id:

ENSRNOP00000084188 ⟸ ENSRNOT00000115786

RefSeq Acc Id:	XP_063129224 ⟸ XM_063273154
- Peptide Label:	isoform X2
- UniProtKB:	A6IK31 (UniProtKB/TrEMBL), A0A8I6APE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001414387 ⟸ NM_001427458
- UniProtKB:	A6IK31 (UniProtKB/TrEMBL), A0A8I6GBK1 (UniProtKB/TrEMBL)

Protein Domains

FAM193 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZIG8-F1-model_v2	AlphaFold	D3ZIG8	1-1436	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309634	AgrOrtholog
BioCyc Gene	G2FUF-15291	BioCyc
Ensembl Genes	ENSRNOG00000013832	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000018616.9	UniProtKB/TrEMBL
	ENSRNOT00000097212	ENTREZGENE
	ENSRNOT00000097212.2	UniProtKB/TrEMBL
	ENSRNOT00000115786	ENTREZGENE
	ENSRNOT00000115786.2	UniProtKB/TrEMBL
InterPro	FAM193	UniProtKB/TrEMBL
	FAM193_C	UniProtKB/TrEMBL
NCBI Gene	305452	ENTREZGENE
PANTHER	PTHR15109	UniProtKB/TrEMBL
	PTHR15109:SF2	UniProtKB/TrEMBL
Pfam	FAM193_C	UniProtKB/TrEMBL
PhenoGen	Fam193a	PhenoGen
RatGTEx	ENSRNOG00000013832	RatGTEx
UniProt	A0A8I6APE8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GBK1	ENTREZGENE, UniProtKB/TrEMBL
	A6IK31	ENTREZGENE, UniProtKB/TrEMBL
	D3ZIG8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Fam193a	family with sequence similarity 193, member A	LOC103690085	protein FAM193A-like	Data merged from RGD:9197066	737654	PROVISIONAL
2014-08-25	LOC103690085	protein FAM193A-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2010-04-23	Fam193a	family with sequence similarity 193, member A	RGD1309634	hypothetical LOC305452	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1309634	hypothetical LOC305452	RGD1309634_predicted	hypothetical LOC305452 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1309634_predicted	hypothetical LOC305452 (predicted)	LOC305452_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC305452_predicted	hypothetical LOC305452 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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