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Gene: Cdkl2 (cyclin dependent kinase like 2) Rattus norvegicus

Analyze

Symbol:

Cdkl2

Name:

cyclin dependent kinase like 2

RGD ID:

1309625

Description:

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in regulation of cell cycle. Predicted to be located in centrosome and nucleoplasm. Predicted to be active in nucleus. Orthologous to human CDKL2 (cyclin dependent kinase like 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cyclin-dependent kinase-like 2; cyclin-dependent kinase-like 2 (CDC2-related kinase); LOC305242

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CDKL2 (cyclin dependent kinase like 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cdkl2 (cyclin dependent kinase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cdkl2 (cyclin dependent kinase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CDKL2 (cyclin dependent kinase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CDKL2 (cyclin dependent kinase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cdkl2 (cyclin dependent kinase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CDKL2 (cyclin dependent kinase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CDKL2 (cyclin dependent kinase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cdkl2 (cyclin dependent kinase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cdkl2 (cyclin dependent kinase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CDKL2 (cyclin dependent kinase like 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cdkl2 (cyclin dependent kinase like 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cdkl2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	16,312,154 - 16,347,524 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	16,312,932 - 16,347,523 (+)	Ensembl				GRCr8
mRatBN7.2	14	16,027,381 - 16,063,257 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	16,028,363 - 16,063,252 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	16,042,194 - 16,064,889 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	17,361,086 - 17,383,777 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	16,053,214 - 16,075,904 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	14	16,228,316 - 16,262,938 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	14	16,209,538 - 16,244,160 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	14	16,215,827 - 16,250,446 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	14	16,241,286 - 16,275,884 (+)	NCBI		F344_StmMcwi
Rnor_6.0	14	17,530,170 - 17,565,950 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	17,531,398 - 17,565,950 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	17,448,431 - 17,483,326 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	17,598,862 - 17,621,559 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	15,421,440 - 15,444,142 (+)	NCBI		Celera
RGSC_v3.1	14	17,598,861 - 17,621,556 (+)	NCBI
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Disease Progression (ISO)

Experimental Mammary Neoplasms (ISO)

Neoplasm Metastasis (ISO)

Neoplastic Cell Transformation (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

1H-pyrazole (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

choline (ISO)

cisplatin (ISO)

clofibrate (ISO)

Cuprizon (EXP)

endosulfan (EXP)

entinostat (ISO)

folic acid (ISO)

L-methionine (ISO)

lead(0) (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methotrexate (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

progesterone (ISO)

rimonabant (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (EXP)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of cell cycle (IEA)

Cellular Component

cytoplasm (IEA)

nucleoplasm (IEA,ISO)

nucleus (IBA,IEA)

Molecular Function

ATP binding (IEA)

cyclin-dependent protein serine/threonine kinase activity (IEA)

kinase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IBA,IEA)

transferase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:24270810	PMID:25931508

Genomics

Comparative Map Data

Cdkl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	16,312,154 - 16,347,524 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	16,312,932 - 16,347,523 (+)	Ensembl				GRCr8
mRatBN7.2	14	16,027,381 - 16,063,257 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	16,028,363 - 16,063,252 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	16,042,194 - 16,064,889 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	17,361,086 - 17,383,777 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	16,053,214 - 16,075,904 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	14	16,228,316 - 16,262,938 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	14	16,209,538 - 16,244,160 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	14	16,215,827 - 16,250,446 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	14	16,241,286 - 16,275,884 (+)	NCBI		F344_StmMcwi
Rnor_6.0	14	17,530,170 - 17,565,950 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	17,531,398 - 17,565,950 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	17,448,431 - 17,483,326 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	17,598,862 - 17,621,559 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	15,421,440 - 15,444,142 (+)	NCBI		Celera
RGSC_v3.1	14	17,598,861 - 17,621,556 (+)	NCBI
Cytogenetic Map	14	p22	NCBI

CDKL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	75,576,496 - 75,630,528 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	75,576,494 - 75,630,716 (-)	Ensembl			hg38	GRCh38
GRCh37	4	76,501,706 - 76,555,712 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	76,720,728 - 76,774,745 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	4	76,861,525 - 76,912,750	NCBI
Celera	4	73,797,824 - 73,851,860 (-)	NCBI		Celera
Cytogenetic Map	4	q21.1	NCBI
HuRef	4	72,248,538 - 72,302,292 (-)	NCBI		HuRef
CHM1_1	4	76,478,463 - 76,532,392 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	78,916,642 - 78,970,655 (-)	NCBI		T2T-CHM13v2.0

Cdkl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	92,153,933 - 92,198,479 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	92,153,933 - 92,191,742 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	92,006,074 - 92,043,042 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	92,006,074 - 92,043,883 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	92,435,101 - 92,472,044 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	93,081,275 - 93,118,218 (-)	NCBI		MGSCv36	mm8
Celera	5	90,149,284 - 90,186,200 (-)	NCBI		Celera
Cytogenetic Map	5	E2	NCBI
cM Map	5	45.73	NCBI

Cdkl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955474	1,513,391 - 1,550,385 (-)	Ensembl
ChiLan1.0	NW_004955474	1,514,566 - 1,550,120 (-)	NCBI	ChiLan1.0	ChiLan1.0

CDKL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	54,442,985 - 54,496,172 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	54,632,780 - 54,685,946 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	48,575,933 - 48,628,916 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	54,411,593 - 54,463,143 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	54,415,305 - 54,458,111 (+)	Ensembl			panPan2	panpan1.1

CDKL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	158,140 - 206,860 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	159,332 - 202,617 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	41,675,076 - 41,723,801 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	181,705 - 230,437 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	181,705 - 230,438 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	178,638 - 227,284 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	136,664 - 183,333 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	39,987,143 - 40,035,866 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cdkl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	11,886,680 - 11,925,061 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936598	339,384 - 377,728 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936598	337,701 - 377,091 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDKL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	71,231,152 - 71,260,815 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	8	71,231,148 - 71,260,902 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	75,370,838 - 75,398,993 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDKL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	24,087,771 - 24,137,348 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	24,087,771 - 24,137,214 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	2,415,240 - 2,464,726 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdkl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	219,730 - 277,898 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	219,722 - 279,866 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cdkl2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	4,843,926 - 4,878,598 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cdkl2
137 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	122
Count of miRNA genes:	100
Interacting mature miRNAs:	111
Transcripts:	ENSRNOT00000046771, ENSRNOT00000050038
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300114	Srn2	Serum renin concentration QTL 2	3.27		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	3957878	21572472	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	14	3957878	18558812	Rat
7411573	Bw139	Body weight QTL 139	4.7	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	14	1	40068101	Rat
9589814	Gluco67	Glucose level QTL 67	4.54	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	40068101	Rat
731183	Pia20	Pristane induced arthritis QTL 20	3.55		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	9393298	39411170	Rat
631212	Bw5	Body weight QTL5	5.43		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	14	11334906	30674469	Rat
2302277	Gluco38	Glucose level QTL 38	5.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	28389666	Rat
1331740	Bw26	Body weight QTL 26	3.028		body mass (VT:0001259)	body weight (CMO:0000012)	14	3957878	31121464	Rat
71117	Niddm17	Non-insulin dependent diabetes mellitus QTL 17	2.35		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	17877928	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8621398	53621398	Rat
70195	Mcs8	Mammary carcinoma susceptibility QTL 8	4.28		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	14	3957878	24886169	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	100078267	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41415516	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1	31893212	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8621398	53621398	Rat
1300140	Srn3	Serum renin concentration QTL 3	3.19		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	15137594	31238250	Rat

Markers in Region

BF397208

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	16,033,628 - 16,033,737 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	17,536,328 - 17,536,436	NCBI	Rnor6.0
Rnor_5.0	14	17,453,706 - 17,453,814	UniSTS	Rnor5.0
RGSC_v3.4	14	17,603,792 - 17,603,900	UniSTS	RGSC3.4
Celera	14	15,426,370 - 15,426,478	UniSTS
Cytogenetic Map	14	p22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	67	165	91	90	59	82	59	6	345	181	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273068	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC136013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY383681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083590	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000046771 ⟹ ENSRNOP00000045371

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	16,312,932 - 16,347,523 (+)	Ensembl
mRatBN7.2 Ensembl	14	16,028,363 - 16,061,386 (+)	Ensembl
Rnor_6.0 Ensembl	14	17,534,442 - 17,563,176 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000050038 ⟹ ENSRNOP00000049130

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	16,312,932 - 16,347,522 (+)	Ensembl
mRatBN7.2 Ensembl	14	16,028,699 - 16,051,371 (+)	Ensembl
Rnor_6.0 Ensembl	14	17,531,398 - 17,554,067 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079304 ⟹ ENSRNOP00000073081

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	16,312,932 - 16,347,523 (+)	Ensembl
mRatBN7.2 Ensembl	14	16,028,363 - 16,063,252 (+)	Ensembl
Rnor_6.0 Ensembl	14	17,534,412 - 17,565,950 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100781 ⟹ ENSRNOP00000078908

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	16,312,932 - 16,347,523 (+)	Ensembl
mRatBN7.2 Ensembl	14	16,028,363 - 16,063,252 (+)	Ensembl

RefSeq Acc Id:

NM_001012035 ⟹ NP_001012035

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,938 - 16,347,524 (+)	NCBI
mRatBN7.2	14	16,028,665 - 16,063,254 (+)	NCBI
Dahl_SR_JrHsd	14	16,228,316 - 16,262,938 (+)	NCBI
Lyon_Normotensive	14	16,209,538 - 16,244,160 (+)	NCBI
Lyon_Hypertensive	14	16,215,827 - 16,250,446 (+)	NCBI
F344_StmMcwi	14	16,241,286 - 16,275,884 (+)	NCBI
Rnor_6.0	14	17,531,398 - 17,554,070 (+)	NCBI
Rnor_5.0	14	17,448,431 - 17,483,326 (+)	NCBI
RGSC_v3.4	14	17,598,862 - 17,621,559 (+)	RGD
Celera	14	15,421,440 - 15,444,142 (+)	RGD

Sequence:

show sequence

CGCCTTCGCCCAGGGCTACTTGACGAGGTGCTGCTTCCCGGAGATGAGCGACCCGAGGGCTTTT
GACAGGCGGTGTTCTCTTTCCCCAGTTCGTTTCTCTGCAGCTCTTGGCCGTGACAGGTGCTAGT
GTCCGTGCCTGTCACAGACGCATTCTGACTCGGGCCCTTCCCCTCTCTCTCTGGAGACTGCCTA
TGGCTGGGGACCGAGTGAGGTCGTTGCCTTGACGACGGCAGCATGCGGCCGGCAGTCCTCGGAA
GTGTGAGCTTGCGGAGGGCAGAAGCCAATCTGCCTCCCTGCCTGCTTCACCTAGGACCAGTAAC
TGCGTCCGCAGAGGAAATCCCAGTACTGGGATTGCTAGTTTGCTAGTCAGCATCTTTTTAGATC
TGCTAGCGAGATGCATATCACCTCAAATTTGTTTCCAAGTTGAAAACCTTTGGCTCTTTCCATG
TGAAGGGTTTGGAAGAAATACAAGAAAAATTCCTACTGGTTTTGAAGCAAAATGGAAAAGTATG
AGAACCTAGGATTGGTTGGAGAGGGGAGTTACGGAATGGTGATGAAGTGTAGGAACAAAGACAG
TGGAAGAATTGTGGCCATTAAGAAGTTCTTAGAGAGCGATGACGATAAAATGGTTAAGAAGATC
GCTATGCGAGAAATCAAGTTACTAAAGCAACTGCGGCATGAAAATTTGGTGAACCTGTTGGAAG
TGTGTAAGAAAAAGAAGCGTTGGTACTTAGTCTTTGAATTTGTTGACCACACGATTCTTGATGA
CTTGAAACTCTTCCCAAATGGACTAGACTATCAAGTAGTTCAAAAGTATTTGTTTCAGATCATT
AATGGAATTGGATTTTGCCATAGTCACAATATCATACACAGAGATATAAAACCCGAGAATATAT
TAGTCTCACAGTCTGGCGTTGTAAAATTATGTGACTTTGGATTCGCACGGACATTGGCGGCTCC
TGGGGAGGTTTACACTGACTATGTGGCCACCCGGTGGTACAGAGCTCCAGAACTGCTGGTCGGT
GATGTCAAGTACGGCAAGGCTGTTGATATCTGGGCCATTGGTTGTCTGGTCATTGAGATGCTTA
TGGGGCAACCACTATTTCCAGGAGAATCCGATATTGATCAGCTGCATCATATTATGACATGTTT
AGGTAATTTAATTCCAAGACACCAGGAGCTATTTTATAAAAATCCTGTGTTTGCTGGAGTAAGG
TTGCCTGAGATCAAAGACATAGAAGCAGAGCCTCTCGAGAGCCGCTATCCGAAGCTCCCTGAAG
TTGTGATCAGTTTAGCAAAGAAATGCTTGCACATTGATCCAGACAAAAGGCCCTTGTGTGCTGA
CCTTCTACACCATGATTTCTTTCAAATGGATGGATTTGCTGAGAGGTTTTCTCAAGAATTGCAG
TTAAAAATAGAGAAAGATGCCAGGAATAATTCTTTACCTAAAAAGTTTCAAATCAGAAAGAAAG
AAAAAGACGATGCCTTAGGTGAAGAAAGAAAAACACTTGTGGTACAGGATACCAATGCTGATCC
CAAAACTAAGGATTCTAAAGTGTTAAAAGTAAAGGGGTCAAAAATCGATGTCGAGAAAACTGAA
AAAGGAACTAGAGCTTCAAATGGCAGCTGTCTCCATGACAACGGGACAAGCCACAAAGGCTTGT
CTTCCACAAGCCTCAGAGATTGCAGCAATGTCACCATTGATCACCCAAGGAATCCAGGCACAGC
GATTCCTCCCCTCACACACAATCTTTCTGCAGTTGCTCCTGGTATCAACGCTGCAATGGGGACT
ATTCCTGGAGTTCAGAATTACAGAGTGGACGAGAAAACTAAGAAATACTGTAATCCTTTTGTTA
AACCAAGCCAGCCTTCTCCATCAGGGATTTATAATATGAATGTGAGCGCATCCGTAAGTAACTG
CCCTCTGCCACGAAAGAGCAAGCACTCGCCGCCTCTAGACCTCGCCGTAAGCATGGGCGCGAGA
AGAGTTAAGCTTTACTTGGAGACAGAGAGTGAAACCTGAGTTACACAGTGCCCTCCTCACTTGT
CAGAGTCGTAATTTGAAATTTCCAATGTCTAAATAAATTTTCTAAGTCTGGTTGAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063273060 ⟹ XP_063129130

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI

RefSeq Acc Id:

XM_063273061 ⟹ XP_063129131

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI

RefSeq Acc Id:

XM_063273062 ⟹ XP_063129132

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI

RefSeq Acc Id:

XM_063273063 ⟹ XP_063129133

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI

RefSeq Acc Id:

XM_063273064 ⟹ XP_063129134

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,945 - 16,347,522 (+)	NCBI

RefSeq Acc Id:

XM_063273065 ⟹ XP_063129135

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI

RefSeq Acc Id:

XM_063273066 ⟹ XP_063129136

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI

RefSeq Acc Id:

XM_063273067 ⟹ XP_063129137

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI

RefSeq Acc Id:

XM_063273068 ⟹ XP_063129138

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI

RefSeq Acc Id:

XR_005492936

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI
mRatBN7.2	14	16,028,657 - 16,063,254 (+)	NCBI

RefSeq Acc Id:

XR_005492937

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI
mRatBN7.2	14	16,027,382 - 16,063,257 (+)	NCBI

RefSeq Acc Id:

XR_005492938

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,923 - 16,347,522 (+)	NCBI
mRatBN7.2	14	16,028,656 - 16,063,254 (+)	NCBI

RefSeq Acc Id:

XR_005492939

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI
mRatBN7.2	14	16,027,382 - 16,063,257 (+)	NCBI

RefSeq Acc Id:

XR_005492940

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI
mRatBN7.2	14	16,027,382 - 16,063,257 (+)	NCBI

RefSeq Acc Id:

XR_005492941

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI
mRatBN7.2	14	16,027,382 - 16,063,257 (+)	NCBI

RefSeq Acc Id:

XR_005492943

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI
mRatBN7.2	14	16,027,382 - 16,063,257 (+)	NCBI

RefSeq Acc Id:

XR_005492944

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI
mRatBN7.2	14	16,027,381 - 16,063,257 (+)	NCBI

RefSeq Acc Id:

XR_005492945

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	16,312,154 - 16,347,522 (+)	NCBI
mRatBN7.2	14	16,027,381 - 16,063,257 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012035	(Get FASTA)	NCBI Sequence Viewer
	XP_063129130	(Get FASTA)	NCBI Sequence Viewer
	XP_063129131	(Get FASTA)	NCBI Sequence Viewer
	XP_063129132	(Get FASTA)	NCBI Sequence Viewer
	XP_063129133	(Get FASTA)	NCBI Sequence Viewer
	XP_063129134	(Get FASTA)	NCBI Sequence Viewer
	XP_063129135	(Get FASTA)	NCBI Sequence Viewer
	XP_063129136	(Get FASTA)	NCBI Sequence Viewer
	XP_063129137	(Get FASTA)	NCBI Sequence Viewer
	XP_063129138	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83590	(Get FASTA)	NCBI Sequence Viewer
	AAQ96239	(Get FASTA)	NCBI Sequence Viewer
	EDL88599	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000045371
	ENSRNOP00000049130
	ENSRNOP00000049130.3
	ENSRNOP00000073081
GenBank Protein	Q5XIT0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001012035 ⟸ NM_001012035

- UniProtKB:

A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLV
NLLEVCKKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIK
PENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDIWAIGCLV
IEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRLPEIKDIEAEPLESRYP
KLPEVVISLAKKCLHIDPDKRPLCADLLHHDFFQMDGFAERFSQELQLKIEKDARNNSLPKKFQ
IRKKEKDDALGEERKTLVVQDTNADPKTKDSKVLKVKGSKIDVEKTEKGTRASNGSCLHDNGTS
HKGLSSTSLRDCSNVTIDHPRNPGTAIPPLTHNLSAVAPGINAAMGTIPGVQNYRVDEKTKKYC
NPFVKPSQPSPSGIYNMNVSASVSNCPLPRKSKHSPPLDLAVSMGARRVKLYLETESET

hide sequence

Ensembl Acc Id:

ENSRNOP00000073081 ⟸ ENSRNOT00000079304

Ensembl Acc Id:

ENSRNOP00000045371 ⟸ ENSRNOT00000046771

Ensembl Acc Id:

ENSRNOP00000049130 ⟸ ENSRNOT00000050038

Ensembl Acc Id:

ENSRNOP00000078908 ⟸ ENSRNOT00000100781

RefSeq Acc Id:	XP_063129130 ⟸ XM_063273060
- Peptide Label:	isoform X1
- UniProtKB:	A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129132 ⟸ XM_063273062
- Peptide Label:	isoform X1
- UniProtKB:	A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129136 ⟸ XM_063273066
- Peptide Label:	isoform X1
- UniProtKB:	A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129137 ⟸ XM_063273067
- Peptide Label:	isoform X1
- UniProtKB:	A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129131 ⟸ XM_063273061
- Peptide Label:	isoform X1
- UniProtKB:	A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129135 ⟸ XM_063273065
- Peptide Label:	isoform X1
- UniProtKB:	A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129133 ⟸ XM_063273063
- Peptide Label:	isoform X1
- UniProtKB:	A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129138 ⟸ XM_063273068
- Peptide Label:	isoform X1
- UniProtKB:	A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129134 ⟸ XM_063273064
- Peptide Label:	isoform X1
- UniProtKB:	A6KKB1 (UniProtKB/TrEMBL), F7F9E5 (UniProtKB/TrEMBL)

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIT0-F1-model_v2	AlphaFold	Q5XIT0	1-507	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309625	AgrOrtholog
BioCyc Gene	G2FUF-16242	BioCyc
Ensembl Genes	ENSRNOG00000002506	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000046771	ENTREZGENE
	ENSRNOT00000050038	ENTREZGENE
	ENSRNOT00000050038.5	UniProtKB/Swiss-Prot
	ENSRNOT00000079304	ENTREZGENE
Gene3D-CATH	Phosphorylase Kinase, domain 1	UniProtKB/Swiss-Prot
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7132550	IMAGE-MGC_LOAD
InterPro	CDK	UniProtKB/Swiss-Prot
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot
KEGG Report	rno:305242	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94313	IMAGE-MGC_LOAD
NCBI Gene	305242	ENTREZGENE
PANTHER	CELL DIVISION PROTEIN KINASE	UniProtKB/Swiss-Prot
	CYCLIN-DEPENDENT KINASE-LIKE 2	UniProtKB/Swiss-Prot
Pfam	Pkinase	UniProtKB/Swiss-Prot
PhenoGen	Cdkl2	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000002506	RatGTEx
SMART	S_TKc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot
UniProt	A0A0G2K4K8_RAT	UniProtKB/TrEMBL
	A6KKB1	ENTREZGENE, UniProtKB/TrEMBL
	CDKL2_RAT	UniProtKB/Swiss-Prot
	F7F9E5	ENTREZGENE, UniProtKB/TrEMBL
	Q5XIT0	ENTREZGENE
	Q6TXH3_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-13	Cdkl2	cyclin dependent kinase like 2	Cdkl2	cyclin-dependent kinase-like 2 (CDC2-related kinase)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Cdkl2	cyclin-dependent kinase-like 2 (CDC2-related kinase)	Cdkl2_predicted	cyclin-dependent kinase-like 2 (CDC2-related kinase) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Cdkl2_predicted	cyclin-dependent kinase-like 2 (CDC2-related kinase) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD