G3bp2 (G3BP stress granule assembly factor 2) - Rat Genome Database

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Gene: G3bp2 (G3BP stress granule assembly factor 2) Rattus norvegicus
Analyze
Symbol: G3bp2
Name: G3BP stress granule assembly factor 2
RGD ID: 1309571
Description: Predicted to enable mRNA binding activity and molecular condensate scaffold activity. Predicted to be involved in protein homooligomerization and stress granule assembly. Predicted to be located in cytoplasm. Predicted to be active in cytoplasmic stress granule and cytosol. Orthologous to human G3BP2 (G3BP stress granule assembly factor 2); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GTPase activating protein (SH3 domain) binding protein 2; LOC305240; ras GTPase-activating protein-binding protein 2; RGD1309571; similar to RNA-binding protein isoform G3BP-2a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81416,216,684 - 16,304,828 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1416,248,744 - 16,304,823 (+)EnsemblGRCr8
mRatBN7.21415,932,403 - 16,020,555 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1415,987,417 - 16,020,548 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxPNT010002061.1764 - 14,667 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01417,261,452 - 17,352,942 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01415,956,911 - 16,045,070 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01417,437,145 - 17,523,254 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1417,492,081 - 17,520,792 (+)Ensemblrn6Rnor6.0
Rnor_5.01417,354,824 - 17,440,632 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41417,556,967 - 17,588,259 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1415,382,373 - 15,410,837 (+)NCBICelera
RGSC_v3.11417,556,966 - 17,588,256 (+)NCBI
Cytogenetic Map14p22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
Benoxacor  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyproconazole  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP)
pentachlorophenol  (ISO)
poly(I:C)  (EXP)
propiconazole  (ISO)
pyrrolidine dithiocarbamate  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:20392851   PMID:22658674   PMID:22681889   PMID:22871113   PMID:23279204   PMID:28131823   PMID:28816235   PMID:34060227  


Genomics

Comparative Map Data
G3bp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81416,216,684 - 16,304,828 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1416,248,744 - 16,304,823 (+)EnsemblGRCr8
mRatBN7.21415,932,403 - 16,020,555 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1415,987,417 - 16,020,548 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxPNT010002061.1764 - 14,667 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01417,261,452 - 17,352,942 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01415,956,911 - 16,045,070 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01417,437,145 - 17,523,254 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1417,492,081 - 17,520,792 (+)Ensemblrn6Rnor6.0
Rnor_5.01417,354,824 - 17,440,632 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41417,556,967 - 17,588,259 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1415,382,373 - 15,410,837 (+)NCBICelera
RGSC_v3.11417,556,966 - 17,588,256 (+)NCBI
Cytogenetic Map14p22NCBI
G3BP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38475,642,786 - 75,724,437 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl475,641,849 - 75,726,301 (-)Ensemblhg38GRCh38
GRCh37476,567,970 - 76,649,621 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36476,786,990 - 76,817,629 (-)NCBIBuild 36Build 36hg18NCBI36
Celera473,864,091 - 73,894,093 (-)NCBICelera
Cytogenetic Map4q21.1NCBI
HuRef472,314,522 - 72,345,439 (-)NCBIHuRef
CHM1_1476,544,613 - 76,575,399 (-)NCBICHM1_1
T2T-CHM13v2.0478,982,913 - 79,064,565 (-)NCBIT2T-CHM13v2.0
G3bp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39592,200,004 - 92,285,584 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl592,200,005 - 92,231,578 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38592,052,145 - 92,137,725 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl592,052,146 - 92,083,719 (-)Ensemblmm10GRCm38
MGSCv37592,481,172 - 92,512,761 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36593,129,700 - 93,158,857 (-)NCBIMGSCv36mm8
Celera590,195,328 - 90,226,988 (-)NCBICelera
Cytogenetic Map5E2NCBI
cM Map545.84NCBI
G3bp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554741,562,163 - 1,632,449 (-)Ensembl
ChiLan1.0NW_0049554741,565,048 - 1,632,427 (-)NCBIChiLan1.0ChiLan1.0
G3BP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2354,348,316 - 54,430,945 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1454,538,058 - 54,620,695 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0448,481,019 - 48,563,664 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1454,368,332 - 54,399,374 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl454,317,504 - 54,399,374 (+)EnsemblpanPan2panpan1.1
G3BP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.132218,783 - 305,734 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl32220,439 - 252,593 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3241,628,351 - 41,662,321 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.032243,197 - 277,215 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl32218,539 - 330,366 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.132240,015 - 273,921 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.032196,041 - 229,980 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03239,940,407 - 39,974,408 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
G3bp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528511,794,747 - 11,876,593 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936598296,193 - 326,900 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936598246,745 - 326,900 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
G3BP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl871,273,126 - 71,363,410 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1871,273,125 - 71,363,474 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2875,411,009 - 75,499,390 (-)NCBISscrofa10.2Sscrofa10.2susScr3
G3BP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1724,149,920 - 24,236,502 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl724,148,750 - 24,180,210 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660372,477,228 - 2,507,624 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
G3bp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624730130,273 - 202,536 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624730130,339 - 201,938 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
G3bp2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1114,886,698 - 4,917,216 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in G3bp2
905 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:18
Interacting mature miRNAs:22
Transcripts:ENSRNOT00000003346
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14395787818558812Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14939329839411170Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141133490630674469Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141133471628389666Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14117877928Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141513759431238250Rat

Markers in Region
D14Rat78  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81416,279,376 - 16,279,486 (+)Marker Load Pipeline
mRatBN7.21415,995,099 - 15,995,211 (+)MAPPERmRatBN7.2
Rnor_6.01417,499,969 - 17,500,078NCBIRnor6.0
Rnor_5.01417,417,347 - 17,417,456UniSTSRnor5.0
RGSC_v3.41417,564,855 - 17,564,965RGDRGSC3.4
RGSC_v3.41417,564,856 - 17,564,965UniSTSRGSC3.4
Celera1415,390,261 - 15,390,370UniSTS
RGSC_v3.11417,564,855 - 17,564,965RGD
SHRSP x BN Map146.9UniSTS
SHRSP x BN Map146.9RGD
Cytogenetic Map14p22UniSTS
D14Hmgc13  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81416,276,405 - 16,276,639 (+)Marker Load Pipeline
mRatBN7.21415,992,128 - 15,992,362 (+)MAPPERmRatBN7.2
Rnor_6.01417,496,999 - 17,497,232NCBIRnor6.0
Rnor_5.01417,414,377 - 17,414,610UniSTSRnor5.0
Celera1415,387,291 - 15,387,524UniSTS
Cytogenetic Map14p22UniSTS
RH125852  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21416,017,892 - 16,018,140 (+)MAPPERmRatBN7.2
Rnor_6.01417,520,592 - 17,520,839NCBIRnor6.0
Rnor_5.01417,437,970 - 17,438,217UniSTSRnor5.0
RGSC_v3.41417,588,056 - 17,588,303UniSTSRGSC3.4
Celera1415,410,634 - 15,410,881UniSTS
Cytogenetic Map14p22UniSTS
RH141183  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21416,018,710 - 16,018,907 (+)MAPPERmRatBN7.2
mRatBN7.2359,363,011 - 59,363,187 (+)MAPPERmRatBN7.2
Rnor_6.0361,371,485 - 61,371,660NCBIRnor6.0
Rnor_6.01417,521,410 - 17,521,606NCBIRnor6.0
Rnor_5.01417,438,788 - 17,438,984UniSTSRnor5.0
Rnor_5.0367,839,469 - 67,839,644UniSTSRnor5.0
RGSC_v3.41417,588,874 - 17,589,070UniSTSRGSC3.4
RGSC_v3.4357,074,290 - 57,074,465UniSTSRGSC3.4
Celera358,886,168 - 58,886,343UniSTS
Celera1415,411,452 - 15,411,648UniSTS
Cytogenetic Map14p22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003346   ⟹   ENSRNOP00000003346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1415,987,676 - 16,018,975 (+)Ensembl
Rnor_6.0 Ensembl1417,492,081 - 17,520,792 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094514   ⟹   ENSRNOP00000091154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1416,271,656 - 16,304,823 (+)Ensembl
mRatBN7.2 Ensembl1415,987,417 - 16,020,548 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117159   ⟹   ENSRNOP00000079770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1415,997,965 - 16,018,968 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121013   ⟹   ENSRNOP00000098566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1416,271,656 - 16,304,823 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121014   ⟹   ENSRNOP00000098567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1416,248,744 - 16,304,823 (+)Ensembl
RefSeq Acc Id: NM_001013989   ⟹   NP_001014011
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81416,271,656 - 16,304,828 (+)NCBI
mRatBN7.21415,987,377 - 16,020,555 (+)NCBI
Rnor_6.01417,492,081 - 17,520,795 (+)NCBI
Rnor_5.01417,354,824 - 17,440,632 (+)NCBI
RGSC_v3.41417,556,967 - 17,588,259 (+)RGD
Celera1415,382,373 - 15,410,837 (+)RGD
Sequence:
RefSeq Acc Id: NM_001401436   ⟹   NP_001388365
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81416,271,656 - 16,304,828 (+)NCBI
mRatBN7.21415,987,377 - 16,020,555 (+)NCBI
RefSeq Acc Id: NM_001401437   ⟹   NP_001388366
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81416,216,684 - 16,304,828 (+)NCBI
mRatBN7.21415,932,403 - 16,020,555 (+)NCBI
RefSeq Acc Id: NM_001401438   ⟹   NP_001388367
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81416,216,684 - 16,304,828 (+)NCBI
mRatBN7.21415,932,403 - 16,020,555 (+)NCBI
RefSeq Acc Id: NM_001401439   ⟹   NP_001388368
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81416,271,911 - 16,304,828 (+)NCBI
mRatBN7.21415,987,632 - 16,020,555 (+)NCBI
RefSeq Acc Id: XM_006250734   ⟹   XP_006250796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81416,271,903 - 16,304,824 (+)NCBI
mRatBN7.21415,987,624 - 16,020,555 (+)NCBI
Rnor_6.01417,492,211 - 17,523,254 (+)NCBI
Rnor_5.01417,354,824 - 17,440,632 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250736   ⟹   XP_006250798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81416,272,485 - 16,304,824 (+)NCBI
mRatBN7.21415,988,204 - 16,020,555 (+)NCBI
Rnor_6.01417,493,128 - 17,523,252 (+)NCBI
Rnor_5.01417,354,824 - 17,440,632 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063273059   ⟹   XP_063129129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81416,272,485 - 16,304,824 (+)NCBI
RefSeq Acc Id: NP_001014011   ⟸   NM_001013989
- Peptide Label: isoform 2
- UniProtKB: Q6AY21 (UniProtKB/TrEMBL),   A0A8I6ABI3 (UniProtKB/TrEMBL),   A0A8I5ZNB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250796   ⟸   XM_006250734
- Peptide Label: isoform X1
- UniProtKB: F7F5P9 (UniProtKB/TrEMBL),   A6KKA6 (UniProtKB/TrEMBL),   A0A8I5ZNB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250798   ⟸   XM_006250736
- Peptide Label: isoform X1
- UniProtKB: F7F5P9 (UniProtKB/TrEMBL),   A6KKA6 (UniProtKB/TrEMBL),   A0A8I5ZNB2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003346   ⟸   ENSRNOT00000003346
Ensembl Acc Id: ENSRNOP00000091154   ⟸   ENSRNOT00000094514
Ensembl Acc Id: ENSRNOP00000079770   ⟸   ENSRNOT00000117159
RefSeq Acc Id: NP_001388366   ⟸   NM_001401437
- Peptide Label: isoform 1
- UniProtKB: F7F5P9 (UniProtKB/TrEMBL),   A6KKA6 (UniProtKB/TrEMBL),   A0A8I5ZNB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388367   ⟸   NM_001401438
- Peptide Label: isoform 2
- UniProtKB: Q6AY21 (UniProtKB/TrEMBL),   A0A8I6ABI3 (UniProtKB/TrEMBL),   A0A8I5ZNB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388365   ⟸   NM_001401436
- Peptide Label: isoform 1
- UniProtKB: F7F5P9 (UniProtKB/TrEMBL),   A6KKA6 (UniProtKB/TrEMBL),   A0A8I5ZNB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388368   ⟸   NM_001401439
- Peptide Label: isoform 2
- UniProtKB: Q6AY21 (UniProtKB/TrEMBL),   A0A8I6ABI3 (UniProtKB/TrEMBL),   A0A8I5ZNB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129129   ⟸   XM_063273059
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ABI3 (UniProtKB/TrEMBL),   Q6AY21 (UniProtKB/TrEMBL),   A0A8I5ZNB2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000098566   ⟸   ENSRNOT00000121013
Ensembl Acc Id: ENSRNOP00000098567   ⟸   ENSRNOT00000121014
Protein Domains
NTF2   RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY21-F1-model_v2 AlphaFold Q6AY21 1-449 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699217
Promoter ID:EPDNEW_R9742
Type:initiation region
Name:G3bp2_1
Description:G3BP stress granule assembly factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01417,492,253 - 17,492,313EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309571 AgrOrtholog
BioCyc Gene G2FUF-16248 BioCyc
Ensembl Genes ENSRNOG00000002433 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000094514 ENTREZGENE
  ENSRNOT00000094514.3 UniProtKB/TrEMBL
  ENSRNOT00000121013.2 UniProtKB/TrEMBL
  ENSRNOT00000121014 ENTREZGENE
  ENSRNOT00000121014.2 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.50 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7132309 IMAGE-MGC_LOAD
InterPro G3BP2_RRM UniProtKB/TrEMBL
  NTF2 UniProtKB/TrEMBL
  NTF2-like_dom UniProtKB/TrEMBL
  Nuclear_transport_factor_2_euk UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  Ras_GTPase_bind_prot UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_RNP1 UniProtKB/TrEMBL
KEGG Report rno:305240 UniProtKB/TrEMBL
MGC_CLONE MGC:94299 IMAGE-MGC_LOAD
NCBI Gene 305240 ENTREZGENE
PANTHER PTHR10693 UniProtKB/TrEMBL
  PTHR10693:SF10 UniProtKB/TrEMBL
Pfam NTF2 UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PhenoGen G3bp2 PhenoGen
PROSITE NTF2_DOMAIN UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002433 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54427 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A8I5ZNB2 ENTREZGENE
  A0A8I6ABI3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L449_RAT UniProtKB/TrEMBL
  A0ABK0LET7_RAT UniProtKB/TrEMBL
  A6KKA6 ENTREZGENE, UniProtKB/TrEMBL
  F7F5P9 ENTREZGENE
  Q6AY21 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-08 G3bp2  G3BP stress granule assembly factor 2  G3bp2  GTPase activating protein (SH3 domain) binding protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 G3bp2  GTPase activating protein (SH3 domain) binding protein 2  RGD1309571  similar to RNA-binding protein isoform G3BP-2a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1309571  similar to RNA-binding protein isoform G3BP-2a  RGD1309571_predicted  similar to RNA-binding protein isoform G3BP-2a (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309571_predicted  similar to RNA-binding protein isoform G3BP-2a (predicted)  LOC305240_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC305240_predicted  similar to RNA-binding protein isoform G3BP-2a (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL