Pbk (PDZ binding kinase) - Rat Genome Database

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Gene: Pbk (PDZ binding kinase) Rattus norvegicus
Analyze
Symbol: Pbk
Name: PDZ binding kinase
RGD ID: 1309565
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in stress-activated MAPK cascade. Predicted to act upstream of or within several processes, including cellular response to UV; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and negative regulation of stress-activated MAPK cascade. Predicted to be located in nucleus. Orthologous to human PBK (PDZ binding kinase); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC290326; lymphokine-activated killer T-cell-originated protein kinase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Pbkem1Dfult
Genetic Models: SD-Pbkem1Dfult
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81544,198,506 - 44,209,572 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1544,198,544 - 44,209,570 (+)EnsemblGRCr8
mRatBN7.21540,022,873 - 40,034,014 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1540,023,002 - 40,034,014 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1541,887,040 - 41,897,909 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01543,037,240 - 43,048,109 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01541,483,331 - 41,494,332 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01542,489,253 - 42,500,377 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1542,489,377 - 42,500,395 (+)Ensemblrn6Rnor6.0
Rnor_5.01549,092,278 - 49,103,401 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41545,227,251 - 45,238,096 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1539,695,399 - 39,706,400 (+)NCBICelera
RGSC_v3.11545,243,243 - 45,253,246 (+)NCBI
Cytogenetic Map15p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,3-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-diaminotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-bromohexadecanoic acid  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bicalutamide  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
deguelin  (ISO)
diallyl trisulfide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dieldrin  (EXP)
dioxygen  (EXP,ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
etoposide  (ISO)
fenofibrate  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fructose  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glycidol  (EXP)
glyphosate  (EXP,ISO)
GW 7647  (ISO)
hydrogen peroxide  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
kojic acid  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
lucanthone  (ISO)
methamphetamine  (EXP,ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylparaben  (ISO)
mitomycin C  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
PhIP  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phytoestrogen  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
zaragozic acid A  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21715333   PMID:25065601   PMID:25575812  


Genomics

Comparative Map Data
Pbk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81544,198,506 - 44,209,572 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1544,198,544 - 44,209,570 (+)EnsemblGRCr8
mRatBN7.21540,022,873 - 40,034,014 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1540,023,002 - 40,034,014 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1541,887,040 - 41,897,909 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01543,037,240 - 43,048,109 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01541,483,331 - 41,494,332 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01542,489,253 - 42,500,377 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1542,489,377 - 42,500,395 (+)Ensemblrn6Rnor6.0
Rnor_5.01549,092,278 - 49,103,401 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41545,227,251 - 45,238,096 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1539,695,399 - 39,706,400 (+)NCBICelera
RGSC_v3.11545,243,243 - 45,253,246 (+)NCBI
Cytogenetic Map15p12NCBI
PBK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38827,809,624 - 27,837,817 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl827,809,621 - 27,838,082 (-)Ensemblhg38GRCh38
GRCh37827,667,141 - 27,695,334 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36827,723,057 - 27,751,268 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34827,723,058 - 27,751,268NCBI
Celera826,627,008 - 26,655,180 (-)NCBICelera
Cytogenetic Map8p21.1NCBI
HuRef826,212,013 - 26,240,449 (-)NCBIHuRef
CHM1_1827,869,078 - 27,897,509 (-)NCBICHM1_1
T2T-CHM13v2.0828,086,996 - 28,115,148 (-)NCBIT2T-CHM13v2.0
Pbk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391466,043,337 - 66,055,271 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1466,043,286 - 66,055,271 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381465,805,911 - 65,817,822 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1465,805,837 - 65,817,822 (+)Ensemblmm10GRCm38
MGSCv371466,424,748 - 66,436,659 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361464,760,021 - 64,771,932 (+)NCBIMGSCv36mm8
Celera1463,558,969 - 63,570,871 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.36NCBI
Pbk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540350,330,981 - 50,352,570 (-)Ensembl
ChiLan1.0NW_00495540350,332,167 - 50,353,147 (-)NCBIChiLan1.0ChiLan1.0
PBK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2746,345,239 - 46,373,526 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1822,059,428 - 22,087,514 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0827,084,789 - 27,112,986 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1824,285,395 - 24,313,658 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl824,285,395 - 24,313,658 (-)EnsemblpanPan2panpan1.1
PBK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12529,751,805 - 29,781,806 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2529,751,848 - 29,781,300 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2530,404,998 - 30,434,687 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02529,943,454 - 29,973,465 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2529,943,487 - 29,972,927 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12529,873,334 - 29,903,317 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02529,754,800 - 29,784,791 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02529,921,110 - 29,951,165 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pbk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049437,861,465 - 7,882,241 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936675704,516 - 722,755 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936675704,001 - 722,769 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PBK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1411,543,603 - 11,566,702 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11411,543,657 - 11,577,286 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21412,722,902 - 12,728,961 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21412,786,445 - 12,795,922 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PBK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1825,921,124 - 25,943,349 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl825,921,133 - 25,943,062 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605216,195,068 - 16,217,479 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pbk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475822,603,039 - 22,625,763 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475822,603,076 - 22,625,817 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pbk
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11258,629,991 - 58,647,349 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pbk
56 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:255
Count of miRNA genes:162
Interacting mature miRNAs:181
Transcripts:ENSRNOT00000064306
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat

Markers in Region
AW538537  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21540,033,316 - 40,033,401 (+)MAPPERmRatBN7.2
Rnor_6.01542,499,680 - 42,499,764NCBIRnor6.0
Rnor_5.01549,092,891 - 49,092,975UniSTSRnor5.0
RGSC_v3.41545,237,401 - 45,237,485UniSTSRGSC3.4
Celera1539,705,705 - 39,705,789UniSTS
Cytogenetic Map15p12UniSTS


Genetic Models
This gene Pbk is modified in the following models/strains:
SD-Pbkem1Dfult    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 163 90 89 58 77 58 6 338 176 11 142 80 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000064306   ⟹   ENSRNOP00000061382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1544,198,544 - 44,209,570 (+)Ensembl
mRatBN7.2 Ensembl1540,023,002 - 40,034,014 (+)Ensembl
Rnor_6.0 Ensembl1542,489,377 - 42,500,395 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000132475   ⟹   ENSRNOP00000100563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1544,198,937 - 44,209,570 (+)Ensembl
RefSeq Acc Id: NM_001079937   ⟹   NP_001073406
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81544,198,569 - 44,209,570 (+)NCBI
mRatBN7.21540,023,010 - 40,034,012 (+)NCBI
Rnor_6.01542,489,374 - 42,500,375 (+)NCBI
Rnor_5.01549,092,278 - 49,103,401 (-)NCBI
RGSC_v3.41545,227,251 - 45,238,096 (+)RGD
Celera1539,695,399 - 39,706,400 (+)RGD
Sequence:
RefSeq Acc Id: XM_006252103   ⟹   XP_006252165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81544,198,506 - 44,209,572 (+)NCBI
mRatBN7.21540,022,873 - 40,034,014 (+)NCBI
Rnor_6.01542,489,253 - 42,500,377 (+)NCBI
Rnor_5.01549,092,278 - 49,103,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252105   ⟹   XP_006252167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81544,199,275 - 44,209,572 (+)NCBI
mRatBN7.21540,023,418 - 40,034,014 (+)NCBI
Rnor_6.01542,489,782 - 42,500,377 (+)NCBI
Rnor_5.01549,092,278 - 49,103,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252106   ⟹   XP_006252168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81544,198,585 - 44,209,572 (+)NCBI
mRatBN7.21540,023,001 - 40,034,014 (+)NCBI
Rnor_6.01542,489,351 - 42,500,377 (+)NCBI
Rnor_5.01549,092,278 - 49,103,401 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001073406   ⟸   NM_001079937
- UniProtKB: A1L1J7 (UniProtKB/TrEMBL),   D4A9B1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252165   ⟸   XM_006252103
- Peptide Label: isoform X1
- UniProtKB: A1L1J7 (UniProtKB/TrEMBL),   D4A9B1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252168   ⟸   XM_006252106
- Peptide Label: isoform X1
- UniProtKB: A1L1J7 (UniProtKB/TrEMBL),   D4A9B1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252167   ⟸   XM_006252105
- Peptide Label: isoform X1
- UniProtKB: A1L1J7 (UniProtKB/TrEMBL),   D4A9B1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061382   ⟸   ENSRNOT00000064306
Ensembl Acc Id: ENSRNOP00000100563   ⟸   ENSRNOT00000132475
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A1L1J7-F1-model_v2 AlphaFold A1L1J7 1-337 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699747
Promoter ID:EPDNEW_R10271
Type:initiation region
Name:Pbk_1
Description:PDZ binding kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01542,489,366 - 42,489,426EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309565 AgrOrtholog
BioCyc Gene G2FUF-13345 BioCyc
Ensembl Genes ENSRNOG00000015308 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064306 ENTREZGENE
  ENSRNOT00000064306.5 UniProtKB/TrEMBL
  ENSRNOT00000132475 ENTREZGENE
  ENSRNOT00000132475.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8375047 IMAGE-MGC_LOAD
InterPro Kinase-like_dom UniProtKB/TrEMBL
  PKc_TOPK UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Ser/Thr_prot_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:290326 UniProtKB/TrEMBL
MGC_CLONE MGC:156686 IMAGE-MGC_LOAD
NCBI Gene 290326 ENTREZGENE
PANTHER LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE UniProtKB/TrEMBL
  MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Pbk PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015308 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0ABK0LJZ8_RAT UniProtKB/TrEMBL
  A1L1J7 ENTREZGENE, UniProtKB/TrEMBL
  D4A9B1 ENTREZGENE
UniProt Secondary D4A9B1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Pbk  PDZ binding kinase   Pbk_predicted  PDZ binding kinase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pbk_predicted  PDZ binding kinase (predicted)      Symbol and Name status set to approved 70820 APPROVED