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Gene: Ankrd54 (ankyrin repeat domain 54) Rattus norvegicus

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Symbol:

Ankrd54

Name:

ankyrin repeat domain 54

RGD ID:

1309552

Description:

Predicted to enable protein kinase regulator activity. Predicted to be involved in positive regulation of erythrocyte differentiation and regulation of intracellular signal transduction. Predicted to act upstream of or within nucleocytoplasmic transport. Predicted to be located in midbody. Predicted to be active in cytoplasm and nucleus. Orthologous to human ANKRD54 (ankyrin repeat domain 54); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ankyrin repeat domain-containing protein 54; LOC362957; RGD1309552; similar to RIKEN cDNA C730048E16

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ANKRD54 (ankyrin repeat domain 54)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Ankrd54 (ankyrin repeat domain 54)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ankrd54 (ankyrin repeat domain 54)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ANKRD54 (ankyrin repeat domain 54)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ANKRD54 (ankyrin repeat domain 54)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ankrd54 (ankyrin repeat domain 54)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ANKRD54 (ankyrin repeat domain 54)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ANKRD54 (ankyrin repeat domain 54)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ankrd54 (ankyrin repeat domain 54)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Ankrd54 (ankyrin repeat domain 54)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ANKRD54 (ankyrin repeat domain 54)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ankrd54 (ankyrin repeat domain 54)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG10809	Alliance	DIOPT (InParanoid\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG10809	Alliance	DIOPT (OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ankrd54	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	112,495,396 - 112,508,186 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	112,495,462 - 112,508,128 (-)	Ensembl				GRCr8
mRatBN7.2	7	110,614,942 - 110,627,739 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	110,614,951 - 110,627,675 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	112,366,271 - 112,377,188 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	114,589,803 - 114,600,720 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	114,558,403 - 114,569,308 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	120,282,423 - 120,295,647 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	120,282,822 - 120,295,618 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	120,273,841 - 120,286,703 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	117,026,119 - 117,037,050 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	106,951,054 - 106,961,977 (-)	NCBI		Celera
RGSC_v3.1	7	117,060,348 - 117,071,280 (-)	NCBI
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-methylcholine (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

chlorpyrifos (ISO)

cocaine (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

doxorubicin (ISO)

FR900359 (ISO)

GSK-J4 (ISO)

ivermectin (ISO)

methyl methanesulfonate (ISO)

ozone (ISO)

paracetamol (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

tetrachloroethene (ISO)

tris(2-butoxyethyl) phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

nucleocytoplasmic transport (ISO)

positive regulation of erythrocyte differentiation (ISO,ISS)

regulation of intracellular signal transduction (IBA,ISO,ISS)

regulation of protein kinase activity (ISO)

Cellular Component

cytoplasm (IBA,IEA,ISO,ISS)

midbody (IEA,ISO,ISS)

nucleus (IBA,IEA,ISO,ISS)

Molecular Function

protein binding (ISO)

protein kinase regulator activity (IBA,IEA,ISO)

protein-containing complex binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:19064729

Genomics

Comparative Map Data

Ankrd54
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	112,495,396 - 112,508,186 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	112,495,462 - 112,508,128 (-)	Ensembl				GRCr8
mRatBN7.2	7	110,614,942 - 110,627,739 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	110,614,951 - 110,627,675 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	112,366,271 - 112,377,188 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	114,589,803 - 114,600,720 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	114,558,403 - 114,569,308 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	120,282,423 - 120,295,647 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	120,282,822 - 120,295,618 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	120,273,841 - 120,286,703 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	117,026,119 - 117,037,050 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	106,951,054 - 106,961,977 (-)	NCBI		Celera
RGSC_v3.1	7	117,060,348 - 117,071,280 (-)	NCBI
Cytogenetic Map	7	q34	NCBI

ANKRD54
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	37,830,855 - 37,849,341 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	37,830,853 - 37,849,327 (-)	Ensembl			hg38	GRCh38
GRCh37	22	38,226,862 - 38,245,348 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	36,556,808 - 36,570,249 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	22	22,028,653 - 22,042,127 (-)	NCBI		Celera
Cytogenetic Map	22	q13.1	NCBI
HuRef	22	21,193,522 - 21,206,728 (-)	NCBI		HuRef
CHM1_1	22	38,185,605 - 38,199,106 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	22	38,292,487 - 38,310,946 (-)	NCBI		T2T-CHM13v2.0

Ankrd54
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	78,937,294 - 78,947,129 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	78,937,294 - 78,947,093 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	79,053,094 - 79,062,927 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	79,053,094 - 79,062,893 (-)	Ensembl			mm10	GRCm38
MGSCv37	15	78,883,524 - 78,893,289 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	78,880,349 - 78,890,114 (-)	NCBI		MGSCv36	mm8
Celera	15	81,154,720 - 81,164,485 (-)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI
cM Map	15	37.7	NCBI

Ankrd54
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	24,203,653 - 24,216,851 (-)	Ensembl
ChiLan1.0	NW_004955413	24,203,653 - 24,216,702 (-)	NCBI	ChiLan1.0	ChiLan1.0

ANKRD54
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	47,691,832 - 47,709,459 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	50,380,210 - 50,397,828 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	18,748,498 - 18,766,233 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	36,579,856 - 36,596,401 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

ANKRD54
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	26,794,405 - 26,806,116 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	26,794,426 - 26,806,131 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	26,749,163 - 26,760,829 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	27,585,968 - 27,597,450 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	27,585,943 - 27,597,448 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	27,309,010 - 27,320,678 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	27,617,244 - 27,629,130 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	27,794,836 - 27,806,308 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ankrd54
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	10,269,980 - 10,280,783 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936492	3,280,367 - 3,291,336 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936492	3,280,318 - 3,291,197 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANKRD54
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	10,003,891 - 10,017,734 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	10,003,858 - 10,017,740 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	7,499,911 - 7,513,774 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ANKRD54
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	20,536,145 - 20,551,114 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	20,535,495 - 20,550,853 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	105,236,012 - 105,256,478 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ankrd54
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	10,071,332 - 10,083,025 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624752	10,071,256 - 10,083,006 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Ankrd54
51 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	433
Count of miRNA genes:	224
Interacting mature miRNAs:	269
Transcripts:	ENSRNOT00000014413
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	92388565	119280177	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	82111245	123048330	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	71621154	114982716	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	73618702	118618702	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	85043242	130043242	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	85497398	130497398	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	83626689	128626689	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
631201	Panci1	Pancreas inflammation QTL 1	0	0.001	pancreas integrity trait (VT:0010560)	percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)	7	73557047	118557047	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	82111245	123048330	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	96700404	118618702	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
10450862	Kidm55	Kidney mass QTL 55	4.9		kidney mass (VT:0002707)	kidney weight (CMO:0000081)	7	72725037	117725037	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
10450856	Livw4	Liver weight QTL 4	3.8		liver mass (VT:0003402)	liver weight (CMO:0000092)	7	72725037	117725037	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	78682549	123682549	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	71621154	119349044	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

BI278594

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	112,497,667 - 112,497,880 (+)	Marker Load Pipeline
mRatBN7.2	7	110,617,212 - 110,617,425 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	120,285,113 - 120,285,325	NCBI	Rnor6.0
Rnor_5.0	7	120,276,113 - 120,276,325	UniSTS	Rnor5.0
RGSC_v3.4	7	117,026,590 - 117,026,802	UniSTS	RGSC3.4
Celera	7	106,951,525 - 106,951,737	UniSTS
RH 3.4 Map	7	817.8	UniSTS
Cytogenetic Map	7	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001025285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006242012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC096473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC093616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000014413 ⟹ ENSRNOP00000014413

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	112,495,462 - 112,508,128 (-)	Ensembl
mRatBN7.2 Ensembl	7	110,614,951 - 110,627,675 (-)	Ensembl
Rnor_6.0 Ensembl	7	120,282,822 - 120,295,618 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098861 ⟹ ENSRNOP00000086964

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	112,497,197 - 112,508,128 (-)	Ensembl
mRatBN7.2 Ensembl	7	110,616,744 - 110,627,675 (-)	Ensembl

RefSeq Acc Id:

NM_001025285 ⟹ NP_001020456

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	112,497,197 - 112,508,128 (-)	NCBI
mRatBN7.2	7	110,616,742 - 110,627,675 (-)	NCBI
Rnor_6.0	7	120,284,642 - 120,295,573 (-)	NCBI
Rnor_5.0	7	120,273,841 - 120,286,703 (-)	NCBI
RGSC_v3.4	7	117,026,119 - 117,037,050 (-)	RGD
Celera	7	106,951,054 - 106,961,977 (-)	RGD

Sequence:

show sequence

CGGGTCCGTTGGTCGGTTCGGAACGAGGCTGGCGCTGCCAGACCCGCGCCTAGCCGTTGCCATG
GCAGCCACCGGCGGGGGCGCGGAGGACGAGTCGCGATCCGGCCGCTCGAGCTCCGAGGGCGAGT
GCGCGGTGGCGCCGGAGCCTCTGGCGGAAGCCGGAGGCCTGTTCTCCTTTGCGGACCTCGGCGC
TGCACTGGGCAGCGGCGCAGGCCTCCCGGGTCGGGCGGTGGGCAGGGCCCAGTCCCCGCTGCGC
TACCTCCAAGTCCTGTGGCAGCAGGACGTCGAGCCTCGCGACGAACTGCGTTGCAAGATTCCCG
CCGGGCGGCTGAGGCGTGCAGCCAGGCCCCACCGACGGCTCGGGCCCACCGGCAAAGAGGTGCA
CGCTCTGAAGAGGCTGAGGGACTCAGCTAATGCCAATGACATAGAAACAGTGCAGCAGCTTCTG
GAAGATGGTGCGGATCCCTGCGCAGCTGATGACAAAGGCCGAACAGCCCTCCATTTTGCTTCCT
GCAATGGCAATGACCAGATTGTGCAGCTTCTCCTGGACCATGGGGCCGACCCCAACCAACAGGA
TGGTCTGGGCAACACCCCATTGCACCTGGCGGCCTGCACCAACCATGTTCCTGTCATCACCACA
CTGCTTCGAGGAGGGGCCCGTGTAGATGCCCTAGACAGAGCTGGCCGCACGCCCCTACACCTGG
CCAAGTCGAAACTGAACATCCTGCAGGAGGGTCATTCTCAGTGCCTGGAAGCCGTCCGCCTAGA
GGTGAAGCAGATCATCCACATGCTACGGGAGTACCTGGAGCGCTTGGGGCGACATGAACAGCGT
GAACGGCTAGATGACCTCTGTACCCGCCTCCAGATGACAAGTACCAAAGAACAGGTGGATGAAG
TGACGGACCTCTTGGCCAGCTTCACCTCCCTCAGTCTGCAGATGCAGAGTATGGAGAAGAGGTA
GCAAGGAAGGCTGCTTCTTGCTTTACCGCCGCACTCCTGCCCTCTGCACATGCTACAGGGAAAG
CCCAAGGGATCTGGAGTTCCACTTTGCCCTTGCCCTGAGATGCTGAGGACAGAACTGACAATGT
GCAACATCTCCCTGGGTCAGGACCACAGCCCCTGCTCCTGCTGCATAATACCAGCTCTGTAGCC
ACACTCCAGGCCCACACGTGCTGTCCTAGCAGACACCACTCCTCCTGTGGCCTCCCTGTCCCTC
AGCCCACCTCAGAGCCCTCTCTCTTCCCAGCCGTGGATTTCCATTACCTCCACCTGGCTTTGGG
TAGGCCGCTCTGAGGCCACCAGGGCTGCTCTGTTCTCTAAGCTCGCCCTGCTCCTTACACCAGC
ACTTCAGTTTAGCCCTGCTCCTGACTTTCAAGGAAACACTGCACTGTGGGGTGTCTCTGAGCAG
AAGAGGGACATTGCTCAAGCTTAGGCCTTCATAAGATTAGGAAGGACCCTTTTTAGCCCAAAGA
AAGATCTGTAACACCTTCTCTCCCAGTCACTGGAACACTACACATGGGAGTCCATTTCACAGCC
TACTTATCAGTGGTTGATAGTGGGTCATGGGCCCAGGTCCTTATCCCAGGATCCTCTAGGCCTT
GGGTGTTTTGATAAGAGGCTATACAGATATATAACTAGAGGTCTTTAGTGGGGAGAAGATTCTG
GATCACCTAGGTGGACTGGATATCACCCCAGGTAGCCCTGGGGAGGAGGCCGGAGGTGACCTAT
GCCATGTGGACGTGAGTCATGGAGGAAGAAGCCAGGAGCTGGCTAAGGACAGCCAGTGGGTCCC
TCGGAGCCTCCAGCAGGGACTGGCTCTGCTGACAACTGCACCAGACAGAGCTCAGCTGGACATG
TTTTTGTTTCTGGCCTCCAGAATTGTGAAAAGAAGTCTGTTGGTTGAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAGG

hide sequence

RefSeq Acc Id:

XM_006242012 ⟹ XP_006242074

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	112,495,396 - 112,508,186 (-)	NCBI
mRatBN7.2	7	110,614,942 - 110,627,739 (-)	NCBI
Rnor_6.0	7	120,282,423 - 120,295,647 (-)	NCBI
Rnor_5.0	7	120,273,841 - 120,286,703 (-)	NCBI

Sequence:

show sequence

TCCCGCACTCTGTTGCCGTGGTTGCAGGCCCCGCCCGCCCGTTCCCTGACAGCGAGGCTTCTCC
TGGAGGGAAGCGGGTCCGTTGGTCGGTTCGGAACGAGGCTGGCGCTGCCAGACCCGCGCCTAGC
CGTTGCCATGGCAGCCACCGGCGGGGGCGCGGAGGACGAGTCGCGATCCGGCCGCTCGAGCTCC
GAGGGCGAGTGCGCGGTGGCGCCGGAGCCTCTGGCGGAAGCCGGAGGCCTGTTCTCCTTTGCGG
ACCTCGGCGCTGCACTGGGCAGCGGCGCAGGCCTCCCGGGTCGGGCGGTGGGCAGGGCCCAGTC
CCCGCTGCGCTACCTCCAAGTCCTGTGGCAGCAGGACGTCGAGCCTCGCGACGAACTGCGTTGC
AAGATTCCCGCCGGGCGGCTGAGGCGTGCAGCCAGGCCCCACCGACGGCTCGGGCCCACCGGCA
AAGAGGTGCACGCTCTGAAGAGGCTGAGGGACTCAGCTAATGCCAATGACATAGAAACAGTGCA
GCAGCTTCTGGAAGATGGTGCGGATCCCTGCGCAGCTGATGACAAAGGCCGAACAGCCCTCCAT
TTTGCTTCCTGCAATGGCAATGACCAGATTGTGCAGCTTCTCCTGGACCATGGGGCCGACCCCA
ACCAACAGGATGGTCTGGGCAACACCCCATTGCACCTGGCGGCCTGCACCAACCATGTTCCTGT
CATCACCACACTGCTTCGAGGAGGGGCCCGTGTAGATGCCCTAGACAGAGCTGGCCGCACGCCC
CTACACCTGGCCAAGTCGAAACTGAACATCCTGCAGGAGGGTCATTCTCAGTGCCTGGAAGCCG
TCCGCCTAGAGGTGAAGCAGATCATCCACATGCTACGGGAGTACCTGGAGCGCTTGGGGCGACA
TGAACAGCGTGAACGGCTAGATGACCTCTGTACCCGCCTCCAGATGACAAGTACCAAAGAACAG
GTGGATGAAGTGACGGACCTCTTGGCCAGCTTCACCTCCCTCAGTCTGCAGATGCAGAGTATGG
AGAAGAGGGCTCCACTGGGGCAGGAGCTGGAGACCTGGGCAGGCTGGAGACCAAGAGCGAGCAG
AGGCAGGACTGAAGGAACCAGTTCCTCAGGCATTGCATCTCTGGGCTCCTCACCCTAGACCTCC
TGGAAGGACTTGAGGCCTAGTTACCAGCCCTCTGGCTGTTAGGGAAGGGACAGGAACCCCAGAA
CAGAGGAAGGTTTGTGTGGCGCGTGCACTGCTATGCTGGGGAAAAATCCACACTAAGAGAAATT
GGGAAATCCGGCTCTGGTGCCCTGGCAGCAGAGGCATAAAGGGCTGCCAGGGTCCTCTGGGCTG
CCGGGCACACCAAGGACTCCTTGCCCCTGACTGGGCTTCTGCTTTGCATATGAAGAGCTATGTA
ACCCAGAATCTCCAGGAAACAGGGACCAATCAATTCCTGAAGCCTGGGCCTCCAGGAACAAGGA
GGTCCTGAATCCCTGTTACCACAGGTTCGGTCCCACACTGCATCTGTTGCTAACTCCCCCAGTG
GCTATGCAGACAGTGAAGGGAGGGCTTGCCAAAGGAAGTTGGCTTCTAGGTTAATCATCAACAC
TGGTCAGGCGGCCAGACAATCTTCCCTGTCCTATTTCCAGCCACAATATTTCCTATAGCCCTGA
ATCAGTTTGAAGAGCCAGCCAGAGACTTGTCTCAGACACTTGAGTGAGTCAGAAAGCACAAGTG
GGCCCTGGGCGCCGGGCTGGGCACGGGGCAGGAAGGAACACAGCTGCAGTAGTCCTCTGGGCTT
CTAGAGCTGGCTGTTGGAGAGGCCCCGATGTGGGGGAGGGCGATGTGTGCAGGGCCGGAAGGAA
AGCTCGTGGCTTCACCTGGGCCCGACTCCTTCTGAACACAAACTGTCATGATGGAGCACTACTC
AGACCACGAATGTTCACAGGTTTGAGGTGGGCCTGCTCCTGCTGCCATCTACACCTGAACAAAC
AGGTTTGCCAGGTTCCCCCACCCAGGCAGCTAGATCCACCTCAGACTCATTATTTCTACCATGC
CTGAAGCCAGAACCTCTTCACGATCCATGTCCTCACAGAGGGTGGAGGTATGTGTTGAGTGCCT
ACTGTGTGCCAACATGTGCAGTTGTCACATTATGTATATACATCTCCCCTGCAGACTTGATTGA
AATAAAGTGTCGGATGCTAGTCTAGCATTCTCCCCACTGCCTGGCTTCCAAAAGCCCTGTATTT
GTGGTGCTTGTGGGATGCGCTTGCTAGACGGGCACATTGTGTGAATGCCCGTCTGACTGATCAG
TGTTCTCAGAAGCAGAGGCCTCACACTCTTCCTTGCCAGAGTTCACAGTACAGTGTACATGGTG
GATAAGATGCACACCTGGTACTAAGACAATGGTCAGAGGTCATGGGGTCAGGAGCCTAGGTAGT
CTGGCTGATCTTTGGGGAGGATACTCCACAAAGGGTGAGGGGTAGGCTACAAAGGAAAGTAGGT
TTGGCCAGGGAGGCGCTAGGCTAGGACCATAGGATAGTGGGGGACCATAGTTGGAGTGGGGGCC
CAGCTCAAACACCTCCAGTTCTACCCAGAGGGCTCCCAACTGGGATTCAGCAGAATTTGAAACC
CACCCCT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001020456	(Get FASTA)	NCBI Sequence Viewer
	XP_006242074	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH93616	(Get FASTA)	NCBI Sequence Viewer
	EDM15827	(Get FASTA)	NCBI Sequence Viewer
	EDM15828	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014413
	ENSRNOP00000086964
GenBank Protein	Q566C8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001020456 ⟸ NM_001025285

- UniProtKB:

Q566C8 (UniProtKB/Swiss-Prot), A6HSP4 (UniProtKB/TrEMBL), A0A8I6A3E9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAATGGGAEDESRSGRSSSEGECAVAPEPLAEAGGLFSFADLGAALGSGAGLPGRAVGRAQSPL
RYLQVLWQQDVEPRDELRCKIPAGRLRRAARPHRRLGPTGKEVHALKRLRDSANANDIETVQQL
LEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQQDGLGNTPLHLAACTNHVPVIT
TLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHSQCLEAVRLEVKQIIHMLREYLERLGRHEQ
RERLDDLCTRLQMTSTKEQVDEVTDLLASFTSLSLQMQSMEKR

hide sequence

RefSeq Acc Id:	XP_006242074 ⟸ XM_006242012
- Peptide Label:	isoform X1
- UniProtKB:	A0A0H2UHI6 (UniProtKB/TrEMBL), A0A8I6A3E9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAATGGGAEDESRSGRSSSEGECAVAPEPLAEAGGLFSFADLGAALGSGAGLPGRAVGRAQSPL RYLQVLWQQDVEPRDELRCKIPAGRLRRAARPHRRLGPTGKEVHALKRLRDSANANDIETVQQL LEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQQDGLGNTPLHLAACTNHVPVIT TLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHSQCLEAVRLEVKQIIHMLREYLERLGRHEQ RERLDDLCTRLQMTSTKEQVDEVTDLLASFTSLSLQMQSMEKRAPLGQELETWAGWRPRASRGR TEGTSSSGIASLGSSP hide sequence

Ensembl Acc Id:

ENSRNOP00000014413 ⟸ ENSRNOT00000014413

Ensembl Acc Id:

ENSRNOP00000086964 ⟸ ENSRNOT00000098861

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q566C8-F1-model_v2	AlphaFold	Q566C8	1-299	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695475

Promoter ID:

EPDNEW_R6000

Type:

multiple initiation site

Name:

Ankrd54_1

Description:

ankyrin repeat domain 54

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	120,295,611 - 120,295,671	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309552	AgrOrtholog
BioCyc Gene	G2FUF-32784	BioCyc
Ensembl Genes	ENSRNOG00000010821	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000014413	ENTREZGENE
	ENSRNOT00000098861	ENTREZGENE
Gene3D-CATH	1.25.40.20	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7311744	IMAGE-MGC_LOAD
InterPro	Ankyrin_rpt	UniProtKB/Swiss-Prot
	Ankyrin_rpt-contain_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:362957	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105715	IMAGE-MGC_LOAD
NCBI Gene	362957	ENTREZGENE
PANTHER	ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54	UniProtKB/Swiss-Prot
	ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61	UniProtKB/Swiss-Prot
Pfam	Ank	UniProtKB/Swiss-Prot
	Ank_2	UniProtKB/Swiss-Prot
PhenoGen	Ankrd54	PhenoGen
PROSITE	ANK_REP_REGION	UniProtKB/Swiss-Prot
	ANK_REPEAT	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000010821	RatGTEx
SMART	ANK	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48403	UniProtKB/Swiss-Prot
UniProt	A0A0H2UHI6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A3E9	ENTREZGENE, UniProtKB/TrEMBL
	A6HSP4	ENTREZGENE, UniProtKB/TrEMBL
	ANR54_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-26	Ankrd54	ankyrin repeat domain 54	RGD1309552	similar to RIKEN cDNA C730048E16	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1309552	similar to RIKEN cDNA C730048E16	RGD1309552_predicted	similar to RIKEN cDNA C730048E16 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1309552_predicted	similar to RIKEN cDNA C730048E16 (predicted)	LOC362957_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC362957_predicted	similar to RIKEN cDNA C730048E16 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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