Maff (MAF bZIP transcription factor F) - Rat Genome Database

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Gene: Maff (MAF bZIP transcription factor F) Rattus norvegicus
Analyze
Symbol: Maff
Name: MAF bZIP transcription factor F
RGD ID: 1309531
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and regulation of epidermal cell differentiation. Predicted to act upstream of or within in utero embryonic development and skeletal muscle cell differentiation. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Orthologous to human MAFF (MAF bZIP transcription factor F); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC366960; transcription factor MafF; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog F; v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,792,787 - 112,804,139 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7112,791,416 - 112,804,147 (+)EnsemblGRCr8
mRatBN7.27110,912,367 - 110,923,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,912,499 - 110,923,851 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7112,660,962 - 112,672,336 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,884,496 - 114,895,870 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,853,854 - 114,865,232 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,580,743 - 120,592,095 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,580,743 - 120,592,095 (+)Ensemblrn6Rnor6.0
Rnor_5.07120,572,094 - 120,586,372 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47117,328,924 - 117,340,276 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7107,245,920 - 107,257,272 (+)NCBICelera
RGSC_v3.17117,361,699 - 117,373,300 (+)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-anisomycin  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(E)-cinnamyl alcohol  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
1-phenyl-1,2-propanedione  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-butoxyethanol  (ISO)
2-hexenal  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
amiodarone  (ISO)
amphetamine  (EXP)
antimony(0)  (ISO)
antimycin A  (ISO)
arachidonic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atazanavir sulfate  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
azoxystrobin  (ISO)
Bandrowski's base  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[d]isothiazol-3-one  (ISO)
benzyl cinnamate  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
brequinar  (ISO)
bromobenzene  (EXP)
buta-1,3-diene  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
captan  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (ISO)
choline  (ISO)
chromium atom  (ISO)
ciguatoxin CTX1B  (ISO)
cinnamyl alcohol  (ISO)
cisplatin  (ISO)
citral  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
D-glucose  (ISO)
DDE  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl malate  (ISO)
diethyl maleate  (ISO)
diethyl sulfate  (ISO)
dioxygen  (EXP,ISO)
diphenylcyclopropenone  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
eugenol  (ISO)
fenamidone  (ISO)
fenvalerate  (EXP)
fluoranthene  (ISO)
fluorescein 5-isothiocyanate  (ISO)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (EXP,ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geranial  (ISO)
geraniol  (ISO)
glucose  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glyphosate  (ISO)
Heliotrine  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (ISO)
hydroquinone  (ISO)
hydroxycitronellal  (ISO)
hypochlorous acid  (ISO)
indometacin  (ISO)
iron dichloride  (ISO)
isoeugenol  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
manganese(II) chloride  (EXP)
menadione  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
methamphetamine  (EXP)
methimazole  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methyl non-2-ynoate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
methyltestosterone  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
Monobutylphthalate  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
n-propyl gallate  (ISO)
naphthalene  (EXP)
nefazodone  (ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (ISO)
obeticholic acid  (ISO)
okadaic acid  (ISO)
organoselenium compound  (ISO)
oxaliplatin  (EXP)
oxazepam  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
pamidronate  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
perillyl aldehyde  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phosgene  (ISO)
phthalic anhydride  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
salicylic acid  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
senecionine  (ISO)
Senkirkine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
Soman  (EXP)
sotorasib  (ISO)
sulfadimethoxine  (EXP)
Sunset Yellow FCF  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
tartrazine  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trametinib  (ISO)
trans-isoeugenol  (ISO)
triacsin C  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12490281   PMID:15087497   PMID:22147266   PMID:23332764  


Genomics

Comparative Map Data
Maff
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,792,787 - 112,804,139 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7112,791,416 - 112,804,147 (+)EnsemblGRCr8
mRatBN7.27110,912,367 - 110,923,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,912,499 - 110,923,851 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7112,660,962 - 112,672,336 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,884,496 - 114,895,870 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,853,854 - 114,865,232 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,580,743 - 120,592,095 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,580,743 - 120,592,095 (+)Ensemblrn6Rnor6.0
Rnor_5.07120,572,094 - 120,586,372 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47117,328,924 - 117,340,276 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7107,245,920 - 107,257,272 (+)NCBICelera
RGSC_v3.17117,361,699 - 117,373,300 (+)NCBI
Cytogenetic Map7q34NCBI
MAFF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,201,994 - 38,216,511 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,200,767 - 38,216,511 (+)Ensemblhg38GRCh38
GRCh372238,598,001 - 38,612,518 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,927,944 - 36,942,460 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342236,934,041 - 36,937,012NCBI
Celera2222,402,653 - 22,417,221 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,564,466 - 21,578,860 (+)NCBIHuRef
CHM1_12238,556,960 - 38,571,506 (+)NCBICHM1_1
T2T-CHM13v2.02238,666,346 - 38,680,861 (+)NCBIT2T-CHM13v2.0
Maff
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,230,813 - 79,243,278 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,230,821 - 79,243,276 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381579,346,621 - 79,359,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,346,621 - 79,359,076 (+)Ensemblmm10GRCm38
MGSCv371579,178,108 - 79,189,506 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361579,174,933 - 79,186,331 (+)NCBIMGSCv36mm8
Celera1581,467,576 - 81,478,973 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Maff
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541324,494,326 - 24,504,728 (+)NCBIChiLan1.0ChiLan1.0
MAFF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,058,144 - 48,073,103 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,746,702 - 50,764,159 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,114,929 - 19,129,901 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,940,064 - 36,954,989 (+)NCBIPanPan1.1PanPan1.1panPan2
MAFF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,475,478 - 26,486,109 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,476,851 - 26,485,931 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1026,432,096 - 26,441,384 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01027,268,184 - 27,277,547 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,268,311 - 27,277,535 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,989,008 - 26,998,285 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,300,235 - 27,309,493 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,477,234 - 27,486,527 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Maff
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,972,908 - 9,983,641 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,986,813 - 2,987,836 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,983,322 - 2,988,900 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAFF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,683,660 - 9,696,023 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.159,683,651 - 9,696,128 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,966,177 - 6,978,613 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAFF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,914,271 - 20,927,032 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1920,901,704 - 20,927,174 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045104,842,820 - 104,857,622 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Maff
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247529,771,303 - 9,781,608 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Maff
65 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:164
Count of miRNA genes:118
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000017181
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
Maff  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27110,921,661 - 110,922,110 (+)MAPPERmRatBN7.2
Rnor_6.07120,589,906 - 120,590,354NCBIRnor6.0
Rnor_5.07120,582,736 - 120,583,184UniSTSRnor5.0
RGSC_v3.47117,338,087 - 117,338,535UniSTSRGSC3.4
Celera7107,255,083 - 107,255,531UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 355 192 11 140 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017181   ⟹   ENSRNOP00000017181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,796,809 - 112,804,147 (+)Ensembl
mRatBN7.2 Ensembl7110,912,499 - 110,923,851 (+)Ensembl
Rnor_6.0 Ensembl7120,580,743 - 120,592,095 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094019   ⟹   ENSRNOP00000097254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,793,183 - 112,804,127 (+)Ensembl
mRatBN7.2 Ensembl7110,912,790 - 110,923,851 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116838   ⟹   ENSRNOP00000082038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,802,306 - 112,804,147 (+)Ensembl
mRatBN7.2 Ensembl7110,913,232 - 110,923,851 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000140807   ⟹   ENSRNOP00000110176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,801,632 - 112,804,147 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000171498   ⟹   ENSRNOP00000101273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,791,416 - 112,804,147 (+)Ensembl
RefSeq Acc Id: NM_001130573   ⟹   NP_001124045
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,792,787 - 112,804,131 (+)NCBI
mRatBN7.27110,912,367 - 110,923,711 (+)NCBI
Rnor_6.07120,580,743 - 120,592,095 (+)NCBI
Rnor_5.07120,572,094 - 120,586,372 (+)NCBI
RGSC_v3.47117,328,924 - 117,340,276 (+)RGD
Celera7107,245,920 - 107,257,272 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242029   ⟹   XP_006242091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,793,050 - 112,804,139 (+)NCBI
mRatBN7.27110,912,634 - 110,923,711 (+)NCBI
Rnor_6.07120,580,830 - 120,591,955 (+)NCBI
Rnor_5.07120,572,094 - 120,586,372 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001124045 (Get FASTA)   NCBI Sequence Viewer  
  XP_006242091 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM15807 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017181.5
  ENSRNOP00000082038.2
  ENSRNOP00000097254
  ENSRNOP00000097254.2
  ENSRNOP00000101273.1
  ENSRNOP00000110176.1
RefSeq Acc Id: NP_001124045   ⟸   NM_001130573
- UniProtKB: D3ZC87 (UniProtKB/TrEMBL),   A6HSR5 (UniProtKB/TrEMBL),   A0A8I5ZUD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242091   ⟸   XM_006242029
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000017181   ⟸   ENSRNOT00000017181
Ensembl Acc Id: ENSRNOP00000082038   ⟸   ENSRNOT00000116838
Ensembl Acc Id: ENSRNOP00000097254   ⟸   ENSRNOT00000094019
Ensembl Acc Id: ENSRNOP00000110176   ⟸   ENSRNOT00000140807
Ensembl Acc Id: ENSRNOP00000101273   ⟸   ENSRNOT00000171498
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZC87-F1-model_v2 AlphaFold D3ZC87 1-156 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695480
Promoter ID:EPDNEW_R6005
Type:initiation region
Name:Maff_1
Description:MAF bZIP transcription factor F
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07120,580,662 - 120,580,722EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309531 AgrOrtholog
BioCyc Gene G2FUF-32764 BioCyc
Ensembl Genes ENSRNOG00000012886 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017181.6 UniProtKB/TrEMBL
  ENSRNOT00000094019 ENTREZGENE
  ENSRNOT00000094019.2 UniProtKB/TrEMBL
  ENSRNOT00000116838.2 UniProtKB/TrEMBL
  ENSRNOT00000140807.1 UniProtKB/TrEMBL
  ENSRNOT00000171498.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
InterPro bZIP_sf UniProtKB/TrEMBL
  Euk_TF_DNA-bd UniProtKB/TrEMBL
  TF_bZIP UniProtKB/TrEMBL
  TF_Maf UniProtKB/TrEMBL
  Transciption_factor_Maf UniProtKB/TrEMBL
KEGG Report rno:366960 UniProtKB/TrEMBL
NCBI Gene 366960 ENTREZGENE
PANTHER PTHR10129 UniProtKB/TrEMBL
  PTHR10129:SF25 UniProtKB/TrEMBL
Pfam bZIP_Maf UniProtKB/TrEMBL
PhenoGen Maff PhenoGen
PROSITE BZIP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012886 RatGTEx
SMART BRLZ UniProtKB/TrEMBL
Superfamily-SCOP Euk_transcr_DNA UniProtKB/TrEMBL
  SSF57959 UniProtKB/TrEMBL
UniProt A0A8I5ZUD9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AW56_RAT UniProtKB/TrEMBL
  A0ABK0L0E5_RAT UniProtKB/TrEMBL
  A0ABK0LH53_RAT UniProtKB/TrEMBL
  A6HSR5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZC87 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 Maff  MAF bZIP transcription factor F  Maff  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-18 Maff  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F  Maff  v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Maff  v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)  Maff  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Maff  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)   Maff_predicted  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Maff_predicted  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) (predicted)      Symbol and Name status set to approved 70820 APPROVED