Rad17 (RAD17 checkpoint clamp loader component)

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Gene: Rad17 (RAD17 checkpoint clamp loader component) Rattus norvegicus

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Symbol:

Rad17

Name:

RAD17 checkpoint clamp loader component

RGD ID:

1309515

Description:

Predicted to enable chromatin binding activity and chromatin-protein adaptor activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in several processes, including mitotic DNA integrity checkpoint signaling; negative regulation of DNA replication; and protein localization to site of double-strand break. Predicted to act upstream of or within DNA damage response. Predicted to be located in chromosome, telomeric region; nucleolus; and nucleoplasm. Predicted to be part of Rad17 RFC-like complex. Predicted to be active in site of double-strand break. Orthologous to human RAD17 (RAD17 checkpoint clamp loader component); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cell cycle checkpoint protein RAD17; LOC310034; RAD17 homolog; RAD17 homolog (S. pombe)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RAD17 (RAD17 checkpoint clamp loader component)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB
Mus musculus (house mouse):	Rad17 (RAD17 checkpoint clamp loader component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rad17 (RAD17 checkpoint clamp loader component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RAD17 (RAD17 checkpoint clamp loader component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RAD17 (RAD17 checkpoint clamp loader component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rad17 (RAD17 checkpoint clamp loader component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RAD17 (RAD17 checkpoint clamp loader component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RAD17 (RAD17 checkpoint clamp loader component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rad17 (RAD17 checkpoint clamp loader component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SAMD8 (sterile alpha motif domain containing 8)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RAD17 (RAD17 checkpoint clamp loader component)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rad17 (RAD17 checkpoint clamp loader component)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rad17 (RAD17 checkpoint clamp loader component)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	hpr-17	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	RAD24	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Rad17	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rad17	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	33,498,335 - 33,528,614 (-)	NCBI		GRCr8
mRatBN7.2	2	31,764,260 - 31,794,542 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	31,764,261 - 31,794,072 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	38,898,690 - 38,928,598 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	36,939,110 - 36,969,086 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	31,796,969 - 31,827,030 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	30,634,353 - 30,664,618 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	30,634,354 - 30,664,163 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	49,793,990 - 49,824,254 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	31,424,504 - 31,454,313 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	31,344,873 - 31,374,682 (-)	NCBI
Celera	2	27,776,957 - 27,806,762 (-)	NCBI		Celera
Cytogenetic Map	2	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-dexrazoxane (ISO)

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

arsenous acid (ISO)

atrazine (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium dichloride (ISO)

chlormequat chloride (EXP)

chromium(6+) (ISO)

cobalt dichloride (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

fulvestrant (ISO)

furan (EXP)

idarubicin (ISO)

Lasiocarpine (ISO)

methapyrilene (EXP)

Nonidet P-40 (ISO)

O-methyleugenol (EXP)

oxybenzone (ISO)

ozone (ISO)

paracetamol (ISO)

pirinixic acid (ISO)

piroxicam (ISO)

potassium chromate (ISO)

promethazine (EXP)

resveratrol (EXP,ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (ISO)

thioacetamide (EXP)

thiram (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vorinostat (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin organization (IEA)

DNA damage checkpoint signaling (IBA)

DNA damage response (ISO)

DNA repair (IBA)

mitotic DNA replication checkpoint signaling (IBA)

mitotic intra-S DNA damage checkpoint signaling (ISO)

negative regulation of DNA replication (ISO)

protein localization to site of double-strand break (ISO)

regulation of phosphorylation (ISO)

Cellular Component

chromosome, telomeric region (ISO)

nucleolus (ISO)

nucleoplasm (IEA,ISO)

Rad17 RFC-like complex (IEA)

site of double-strand break (ISO)

Molecular Function

ATP binding (IEA)

chromatin binding (IBA)

chromatin-protein adaptor activity (ISO)

DNA clamp loader activity (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10593953	PMID:12477932	PMID:14657349	PMID:15149599	PMID:15297881	PMID:15538388

Genomics

Comparative Map Data

Rad17
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	33,498,335 - 33,528,614 (-)	NCBI		GRCr8
mRatBN7.2	2	31,764,260 - 31,794,542 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	31,764,261 - 31,794,072 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	38,898,690 - 38,928,598 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	36,939,110 - 36,969,086 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	31,796,969 - 31,827,030 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	30,634,353 - 30,664,618 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	30,634,354 - 30,664,163 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	49,793,990 - 49,824,254 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	31,424,504 - 31,454,313 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	31,344,873 - 31,374,682 (-)	NCBI
Celera	2	27,776,957 - 27,806,762 (-)	NCBI		Celera
Cytogenetic Map	2	q12	NCBI

RAD17
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	69,369,293 - 69,414,801 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	69,369,293 - 69,414,801 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	68,665,120 - 68,710,628 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	68,700,880 - 68,746,384 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	68,701,394 - 68,746,382	NCBI
Celera	5	65,667,788 - 65,713,573 (+)	NCBI		Celera
Cytogenetic Map	5	q13.2	NCBI
HuRef	5	65,621,167 - 65,666,871 (+)	NCBI		HuRef
CHM1_1	5	68,664,968 - 68,710,363 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	70,195,078 - 70,240,793 (+)	NCBI		T2T-CHM13v2.0

Rad17
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	100,753,672 - 100,787,569 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	100,753,672 - 100,787,559 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	100,617,164 - 100,651,061 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	100,617,164 - 100,651,051 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	101,387,119 - 101,421,014 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	101,717,422 - 101,751,091 (-)	NCBI		MGSCv36	mm8
Celera	13	104,227,151 - 104,261,234 (-)	NCBI		Celera
Cytogenetic Map	13	D1	NCBI
cM Map	13	53.23	NCBI

Rad17
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955575	78,335 - 115,129 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955575	78,686 - 115,072 (+)	NCBI	ChiLan1.0	ChiLan1.0

RAD17
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	44,504,519 - 44,550,381 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	42,658,144 - 42,704,006 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	44,586,083 - 44,630,719 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	46,156,294 - 46,202,197 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	46,156,294 - 46,202,197 (-)	Ensembl	panpan1.1		panPan2

RAD17
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	54,407,184 - 54,437,676 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	54,407,228 - 54,437,632 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	51,373,442 - 51,404,005 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	54,918,224 - 54,949,486 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	54,918,240 - 54,949,601 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	51,976,717 - 52,013,771 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	52,750,007 - 52,780,574 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	53,640,400 - 53,670,962 (+)	NCBI		UU_Cfam_GSD_1.0

Rad17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	191,279,855 - 191,315,720 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	216,208 - 252,070 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936480	216,216 - 252,178 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAD17
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	47,499,669 - 47,529,702 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	47,499,669 - 47,529,703 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	51,424,228 - 51,448,330 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAD17
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	65,456,174 - 65,501,665 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	65,457,763 - 65,501,157 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666049	14,192,461 - 14,238,156 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rad17
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624905	249,511 - 276,922 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624905	244,811 - 277,362 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rad17
274 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	51
Count of miRNA genes:	49
Interacting mature miRNAs:	51
Transcripts:	ENSRNOT00000024801
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	11591100	56591100	Rat
7387318	Stl32	Serum triglyceride level QTL 32	3.2	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	22384627	67384627	Rat
631682	Bp115	Blood pressure QTL 115	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	1	37410502	Rat
10755434	Coatc7	Coat color QTL 7		0.04794	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	30648065	75648065	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
738010	Lnnr3	Liver neoplastic nodule remodeling QTL 3	2.94		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	2	1	41244106	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300160	Hrtrt3	Heart rate QTL 3	3.62		heart pumping trait (VT:2000009)	absolute change in heart rate (CMO:0000534)	2	29971593	51729300	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	20304672	65304672	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
738012	Anxrr3	Anxiety related response QTL 3	3.8		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	2	9023519	54023519	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	25413423	143657569	Rat
10402051	Gdil2	Gastrointestinal dilation QTL 2			enteric ganglion morphology trait (VT:0001045)	length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)	2	24903853	74786777	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	27157160	72157160	Rat
1331764	Bp205	Blood pressure QTL 205	3.476		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	26999571	43154682	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1600379	Mcs18	Mammary carcinoma susceptibility QTL 18	2.6		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	7887772	42804738	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1643006	Pain1	Pain QTL 1	3.63	0.005	mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	2	26999571	48268661	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	5873687	102844969	Rat
2300168	Bmd47	Bone mineral density QTL 47	6.6	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	2	20662448	65662448	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	81754745	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	11852062	49003364	Rat
1357990	Ael1	Aortic elastin QTL 1	3.1	0.00091	aorta elastin amount (VT:0003905)	aortic elastin	2	19076825	64076825	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	26917817	136917119	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	28484589	169504100	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	16491740	61491740	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	28484589	169504100	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	127469484	Rat

Markers in Region

RH142847

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	31,794,893 - 31,795,007 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	30,664,985 - 30,665,098	NCBI	Rnor6.0
Rnor_5.0	2	49,824,621 - 49,824,734	UniSTS	Rnor5.0
RGSC_v3.4	2	31,455,135 - 31,455,248	UniSTS	RGSC3.4
Celera	2	27,807,584 - 27,807,697	UniSTS
RH 3.4 Map	2	78.3	UniSTS
Cytogenetic Map	2	q12	UniSTS

UniSTS:237096

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	31,770,182 - 31,770,289 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	30,640,276 - 30,640,382	NCBI	Rnor6.0
Rnor_5.0	2	49,799,913 - 49,800,019	UniSTS	Rnor5.0
RGSC_v3.4	2	31,430,427 - 31,430,533	UniSTS	RGSC3.4
Celera	2	27,782,880 - 27,782,986	UniSTS
Cytogenetic Map	2	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024778	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281719	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC135826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC098057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024801 ⟹ ENSRNOP00000024801

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	31,764,261 - 31,794,072 (-)	Ensembl
Rnor_6.0 Ensembl	2	30,634,354 - 30,664,163 (-)	Ensembl

RefSeq Acc Id:

NM_001024778 ⟹ NP_001019949

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	33,498,335 - 33,528,144 (-)	NCBI
mRatBN7.2	2	31,764,260 - 31,794,072 (-)	NCBI
Rnor_6.0	2	30,634,353 - 30,664,163 (-)	NCBI
Rnor_5.0	2	49,793,990 - 49,824,254 (-)	NCBI
RGSC_v3.4	2	31,424,504 - 31,454,313 (-)	RGD
Celera	2	27,776,957 - 27,806,762 (-)	RGD

Sequence:

show sequence

GTAAGCGCCCGCAGTAAGGAAGGTCCCCAGGAGGCGGGCCGCCCTAGAAGCCTGCGGCTGAGCT
GGGAGGGCTGGGCGGTTACCCTTCCACACTACAGCCTGGCCTCCTTCACATCTTTCCGCCCGCG
AGGGGACGCAGCTCCCAGAAAGTGAATTATACTTCAATATACTCTAAATTGTATGCTACTGATG
GGAACTGTTAAAGTTTATAATGTCAGAAACTTTCCTTAGACCAAAGGTGTCTTCTACAAAGGTA
ACAGACTGGGTAGATCCGGCATTTGATGACTTTTCAGCGAACACTGCTGTCACCACCATCACCG
TTTCATCTCTAAGTTTGAATAACTCCAGTCACAGAAGAAAATACTTGCCCTCCACATTAGAAAG
TAACAGATTGTCTGCTAGGAAAAGAGGAAGGCTGCCTTTAGAACAGACTAATGGTCTAGAAACG
TCAAAAGAATATCTGTCTGACGATGAGCCATGGGTGGATAAGTATAAACCAGAAACTCAGCATG
AGCTTGCTGTCCATAAAAAGAAAATTGAAGAAGTTGAAACCTGGTTAAAAACTCAAGTCTTAGA
AGTGAAGCCGAAACACGGTGGGTCTATTTTATTAATAACAGGTCCTCCAGGATGTGGAAAGACA
ACTACTATAAAAATACTGTCAAAGGAGCTTGGGATTCAAGTACAAGAATGGGTTAATCCCATTT
TACAAGACTTCCAAAAAGATGATTACAAGGAGTTATTTAATTCAGAGTCAAACTTCTCTGTCAT
TCCATACCAATCTCAGATAGCAGTCTTCAATGACTTTCTGTTAAGAGCCACCAAGTACAACAAA
TTGCAGATGCTTGGAGATGCCCTGACAACAGATAAGAAGATAATTCTGGTTGAGGATCTACCTA
ACCAATTTTATCGAGATGCTAATGCTTTACACGAAATTCTAAGGAAGTATGTGCACATCGGCCG
GTGTCCTCTTGTATTTATAGTCTCTGACAGTGTCAGTGGAGATAGTAATCATCGGTTACTCTTT
CCCAAAAACATTCAAGAAGAGTGTTCTGTTTCAAATATTAGTTTCAACCCTGTGGCACCAACAA
TTATGATGAAATTTCTTAATCGAATTGTGACTATAGAAGCTAGTAAGAATGGAGAAAAAATTAC
TGTTCCTAATAAAGCTTCTTTGGAGTTGCTCTGTCAAGGATGTTCTGGTGATATCAGAAGTGCA
ATAAACAGCCTGCAGTTTTCTTCTTCAAAAGGAGAGAACAGTTCATGGTCAAAGAAGAAAAAGA
TGTCATTGAAATCAGATGCTTCGATTTCAAAAGCAAAGCAGAAAAGGAAACATAATAGTACTTT
GGAAAATCAGGAGATTCAAGCTATTGGTGGAAAAGATGTCTCTCTTTTTCTCTTCAGAGCTTTG
GGGAAAATTCTGTACTGTAAAAGAGCACCTTTAACAGAGCTCGCCTCGCCTCGCCTGCCGGCTC
ACTTGTCAGAGCATGACCGGGATACTTTGCTTGTTCAGCCCGAGGAAATAGTAGAAATGTCACA
CATGCCAGGAGAATTTTTTAATTTGTACCTTCACCAAAACTACATAGATTTCTTCACCGACGTA
GATGACCTTGTGAGAGCCAGTGAGTTTCTGAGTTTTGCAGATATCCTCGGTGGTGACTGGAATA
CGCGCTCTTCACTCAGGGACTATAGTACATCTATAGCTGCAAGAGGTGTGATGCATTCCAATAC
ATCTCGGAGATTCGCTCATTGCCAAGGAGGGGGATCCAGCTTTCGACCCTTACATAAGCCCCAA
TGGTTTCTAATACAGAAAAAGTATCGGGAAAATTGCCTGGCAGCGAAAGCACTCTTCTGTGACT
TCTGCCTACCCGCTGTGTGTCTGCAGACTCAGCTCTTGCCTTATCTTGCTCTTCTGACCATTCC
AATGCGAAACAAAGCTCAGATTTCTTTTATCCAAGATATTGGAAGACTTCCTTTGAAGCGAAAC
TTTGGGAGGTTGAAAATGGAGGCCCTGACTGACCGAGAGCTCGGGCTCATAGACCCTGACAGCG
GGGATGAATTGCTGCACAGTGGAGGACAGCCTGCTCAGGAGGCTCAGGGCCAGCCCGCCCAGAC
TGCTGACCCAGAAACCTGGTCTCTCCCTTTGAGTCAGAACAGTGGGAGCGATCTGCCTGCCAGC
CAGCCTCGGCCCTTTTCCTCCAAAGTGGACCTGGAAGAGGAGGAGGAGGAAGAGGAAGACATAG
TAATAGAGGACTATGACAGCGATGAGGCATAGAGAACAGCCCGCCAATCAGACTGCTGCGTGAG
AGTCATCGGTTTAAGTCTATTCAGTGGTACTTGAGCAGCATTCACAGGTCTCTGAAGGACCAGC
TTTGTTAATTGCTCAGTTCCTGATAGTAATCATCACGGCAGCTGCCGCCTGTCATCTTGAAGTA
AAGCAGGTCTCAAGTACTCAGTGCTCAGTATTTATTTAGTCTTGTGTATGGTTTAAGGAGAGGT
CACGGTGTGAAGAATGTATGGATGTTGTGCTAAATATCAGAGAATGTGAAGGAATAATCCAGAA
CATACAGACTTTATGGGGCGTTGTAAATTTGATTTATAAAACCTTTTAGGATGCAATTATGAGT
ATAAATAAACTTTGTGCCTTATTCACAGTTTGCATCTAGCATCTCGGGTACCGTTTTGGTATGT
TGTACAGTGAAATATTTTAGATACTTCTGGAAAGTATTTACATAATTTATATCGAAATTAAAAA
TGTTGGATTTCAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006231848 ⟹ XP_006231910

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	33,498,335 - 33,528,614 (-)	NCBI
mRatBN7.2	2	31,764,260 - 31,794,542 (-)	NCBI
Rnor_6.0	2	30,634,353 - 30,664,618 (-)	NCBI
Rnor_5.0	2	49,793,990 - 49,824,254 (-)	NCBI

Sequence:

show sequence

CCTGACGCGACCACGACACCGCACGCCGCGCGGCCTGAGGAGCCCCGAGGCCGAACACCCAGCG
CCCCCCGGGACCTCACAGCACTCGACAAACCCCGGCCCGGCCTGGCCCAGTCCCGCCGCGCGCC
CTAACCGGTGAATTATACTTCAATATACTCTAAATTGTATGCTACTGATGGGAACTGTTAAAGT
TTATAATGTCAGAAACTTTCCTTAGACCAAAGGTGTCTTCTACAAAGGTAACAGACTGGGTAGA
TCCGGCATTTGATGACTTTTCAGCGAACACTGCTGTCACCACCATCACCGTTTCATCTCTAAGT
TTGAATAACTCCAGTCACAGAAGAAAATACTTGCCCTCCACATTAGAAAGTAACAGATTGTCTG
CTAGGAAAAGAGGAAGGCTGCCTTTAGAACAGACTAATGGTCTAGAAACGTCAAAAGAATATCT
GTCTGACGATGAGCCATGGGTGGATAAGTATAAACCAGAAACTCAGCATGAGCTTGCTGTCCAT
AAAAAGAAAATTGAAGAAGTTGAAACCTGGTTAAAAACTCAAGTCTTAGAAGTGAAGCCGAAAC
ACGGTGGGTCTATTTTATTAATAACAGGTCCTCCAGGATGTGGAAAGACAACTACTATAAAAAT
ACTGTCAAAGGAGCTTGGGATTCAAGTACAAGAATGGGTTAATCCCATTTTACAAGACTTCCAA
AAAGATGATTACAAGGAGTTATTTAATTCAGAGTCAAACTTCTCTGTCATTCCATACCAATCTC
AGATAGCAGTCTTCAATGACTTTCTGTTAAGAGCCACCAAGTACAACAAATTGCAGATGCTTGG
AGATGCCCTGACAACAGATAAGAAGATAATTCTGGTTGAGGATCTACCTAACCAATTTTATCGA
GATGCTAATGCTTTACACGAAATTCTAAGGAAGTATGTGCACATCGGCCGGTGTCCTCTTGTAT
TTATAGTCTCTGACAGTGTCAGTGGAGATAGTAATCATCGGTTACTCTTTCCCAAAAACATTCA
AGAAGAGTGTTCTGTTTCAAATATTAGTTTCAACCCTGTGGCACCAACAATTATGATGAAATTT
CTTAATCGAATTGTGACTATAGAAGCTAGTAAGAATGGAGAAAAAATTACTGTTCCTAATAAAG
CTTCTTTGGAGTTGCTCTGTCAAGGATGTTCTGGTGATATCAGAAGTGCAATAAACAGCCTGCA
GTTTTCTTCTTCAAAAGGAGAGAACAGTTCATGGTCAAAGAAGAAAAAGATGTCATTGAAATCA
GATGCTTCGATTTCAAAAGCAAAGCAGAAAAGGAAACATAATAGTACTTTGGAAAATCAGGAGA
TTCAAGCTATTGGTGGAAAAGATGTCTCTCTTTTTCTCTTCAGAGCTTTGGGGAAAATTCTGTA
CTGTAAAAGAGCACCTTTAACAGAGCTCGCCTCGCCTCGCCTGCCGGCTCACTTGTCAGAGCAT
GACCGGGATACTTTGCTTGTTCAGCCCGAGGAAATAGTAGAAATGTCACACATGCCAGGAGAAT
TTTTTAATTTGTACCTTCACCAAAACTACATAGATTTCTTCACCGACGTAGATGACCTTGTGAG
AGCCAGTGAGTTTCTGAGTTTTGCAGATATCCTCGGTGGTGACTGGAATACGCGCTCTTCACTC
AGGGACTATAGTACATCTATAGCTGCAAGAGGTGTGATGCATTCCAATACATCTCGGAGATTCG
CTCATTGCCAAGGAGGGGGATCCAGCTTTCGACCCTTACATAAGCCCCAATGGTTTCTAATACA
GAAAAAGTATCGGGAAAATTGCCTGGCAGCGAAAGCACTCTTCTGTGACTTCTGCCTACCCGCT
GTGTGTCTGCAGACTCAGCTCTTGCCTTATCTTGCTCTTCTGACCATTCCAATGCGAAACAAAG
CTCAGATTTCTTTTATCCAAGATATTGGAAGACTTCCTTTGAAGCGAAACTTTGGGAGGTTGAA
AATGGAGGCCCTGACTGACCGAGAGCTCGGGCTCATAGACCCTGACAGCGGGGATGAATTGCTG
CACAGTGGAGGACAGCCTGCTCAGGAGGCTCAGGGCCAGCCCGCCCAGACTGCTGACCCAGAAA
CCTGGTCTCTCCCTTTGAGTCAGAACAGTGGGAGCGATCTGCCTGCCAGCCAGCCTCGGCCCTT
TTCCTCCAAAGTGGACCTGGAAGAGGAGGAGGAGGAAGAGGAAGACATAGTAATAGAGGACTAT
GACAGCGATGAGACATAGAGAACAGCCCGCCAATCAGACTGCTGCGTGAGAGTCATCGGTTTAA
GTCTATTCAGTGGTACTTGAGCAGCATTCACAGGTCTCTGAAGGACCAGCTTTGTTAATTGCTC
AGTTCCTGATAGTAATCATCACGGCAGCTGCCGCCTGTCATCTTGAAGTAAAGCAGGTCTCAAG
TACTCAGTGCTCAGTATTTATTTAGTCTTGTGTATGGTTTAAGGAGAGGTCACGGTGTGAAGAA
TGTATGGATGTTGTGCTAAATATCAGAGAATGTGAAGGAATAATCCAGAACATACAGACTTTAT
GGGGCGTTGTAAATTTGATTTATAAAACCTTTTAGGATGCAATTATGAGTATAAATAAACTTTG
TGCCTTATTCACAGTTTGCATCTAGCATCTCGGGTACCGTTTTGGTATGTTGTACAGTGAAATA
TTTTAGATACTTCTGGAAAGTATTTACATAATTTATATCGAAATTAAAAATGTTGGATTTCA

hide sequence

RefSeq Acc Id:

XM_039102173 ⟹ XP_038958101

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	33,498,335 - 33,527,042 (-)	NCBI
mRatBN7.2	2	31,764,260 - 31,794,051 (-)	NCBI

RefSeq Acc Id:

XM_063281719 ⟹ XP_063137789

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	33,499,015 - 33,528,129 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001019949	(Get FASTA)	NCBI Sequence Viewer
	XP_006231910	(Get FASTA)	NCBI Sequence Viewer
	XP_038958101	(Get FASTA)	NCBI Sequence Viewer
	XP_063137789	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH98057	(Get FASTA)	NCBI Sequence Viewer
	EDM10204	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000024801.4

RefSeq Acc Id:

NP_001019949 ⟸ NM_001024778

- UniProtKB:

Q4V7A2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSETFLRPKVSSTKVTDWVDPAFDDFSANTAVTTITVSSLSLNNSSHRRKYLPSTLESNRLSAR
KRGRLPLEQTNGLETSKEYLSDDEPWVDKYKPETQHELAVHKKKIEEVETWLKTQVLEVKPKHG
GSILLITGPPGCGKTTTIKILSKELGIQVQEWVNPILQDFQKDDYKELFNSESNFSVIPYQSQI
AVFNDFLLRATKYNKLQMLGDALTTDKKIILVEDLPNQFYRDANALHEILRKYVHIGRCPLVFI
VSDSVSGDSNHRLLFPKNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKITVPNKAS
LELLCQGCSGDIRSAINSLQFSSSKGENSSWSKKKKMSLKSDASISKAKQKRKHNSTLENQEIQ
AIGGKDVSLFLFRALGKILYCKRAPLTELASPRLPAHLSEHDRDTLLVQPEEIVEMSHMPGEFF
NLYLHQNYIDFFTDVDDLVRASEFLSFADILGGDWNTRSSLRDYSTSIAARGVMHSNTSRRFAH
CQGGGSSFRPLHKPQWFLIQKKYRENCLAAKALFCDFCLPAVCLQTQLLPYLALLTIPMRNKAQ
ISFIQDIGRLPLKRNFGRLKMEALTDRELGLIDPDSGDELLHSGGQPAQEAQGQPAQTADPETW
SLPLSQNSGSDLPASQPRPFSSKVDLEEEEEEEEDIVIEDYDSDEA

hide sequence

RefSeq Acc Id:	XP_006231910 ⟸ XM_006231848
- Peptide Label:	isoform X1
- UniProtKB:	E9PTL1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSETFLRPKVSSTKVTDWVDPAFDDFSANTAVTTITVSSLSLNNSSHRRKYLPSTLESNRLSAR KRGRLPLEQTNGLETSKEYLSDDEPWVDKYKPETQHELAVHKKKIEEVETWLKTQVLEVKPKHG GSILLITGPPGCGKTTTIKILSKELGIQVQEWVNPILQDFQKDDYKELFNSESNFSVIPYQSQI AVFNDFLLRATKYNKLQMLGDALTTDKKIILVEDLPNQFYRDANALHEILRKYVHIGRCPLVFI VSDSVSGDSNHRLLFPKNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKITVPNKAS LELLCQGCSGDIRSAINSLQFSSSKGENSSWSKKKKMSLKSDASISKAKQKRKHNSTLENQEIQ AIGGKDVSLFLFRALGKILYCKRAPLTELASPRLPAHLSEHDRDTLLVQPEEIVEMSHMPGEFF NLYLHQNYIDFFTDVDDLVRASEFLSFADILGGDWNTRSSLRDYSTSIAARGVMHSNTSRRFAH CQGGGSSFRPLHKPQWFLIQKKYRENCLAAKALFCDFCLPAVCLQTQLLPYLALLTIPMRNKAQ ISFIQDIGRLPLKRNFGRLKMEALTDRELGLIDPDSGDELLHSGGQPAQEAQGQPAQTADPETW SLPLSQNSGSDLPASQPRPFSSKVDLEEEEEEEEDIVIEDYDSDET hide sequence

Ensembl Acc Id:

ENSRNOP00000024801 ⟸ ENSRNOT00000024801

RefSeq Acc Id:	XP_038958101 ⟸ XM_039102173
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063137789 ⟸ XM_063281719
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-E9PTL1-F1-model_v2	AlphaFold	E9PTL1	1-686	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691106

Promoter ID:

EPDNEW_R1631

Type:

initiation region

Name:

Rad17_1

Description:

RAD17 checkpoint clamp loader component

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	30,664,118 - 30,664,178	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309515	AgrOrtholog
BioCyc Gene	G2FUF-54657	BioCyc
Ensembl Genes	ENSRNOG00000018353	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024801.5	UniProtKB/TrEMBL
Gene3D-CATH	1.10.8.60	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7457767	IMAGE-MGC_LOAD
InterPro	Checkpoint_prot_Rad24	UniProtKB/TrEMBL
	Checkpoint_prot_Rad24_fun/met	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
KEGG Report	rno:310034	UniProtKB/TrEMBL
MGC_CLONE	MGC:116215	IMAGE-MGC_LOAD
NCBI Gene	310034	ENTREZGENE
PANTHER	CELL CYCLE CHECKPOINT PROTEIN RAD17	UniProtKB/TrEMBL
	Rad24	UniProtKB/TrEMBL
Pfam	Rad17	UniProtKB/TrEMBL
PhenoGen	Rad17	PhenoGen
RatGTEx	ENSRNOG00000018353	RatGTEx
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A6I596_RAT	UniProtKB/TrEMBL
	E9PTL1	ENTREZGENE, UniProtKB/TrEMBL
	Q4V7A2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-01	Rad17	RAD17 checkpoint clamp loader component	Rad17	RAD17 homolog (S. pombe)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Rad17	RAD17 homolog (S. pombe)	Rad17_predicted	RAD17 homolog (S. pombe) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Rad17_predicted	RAD17 homolog (S. pombe) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar