Nptx2 (neuronal pentraxin 2) - Rat Genome Database

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Gene: Nptx2 (neuronal pentraxin 2) Rattus norvegicus
Analyze
Symbol: Nptx2
Name: neuronal pentraxin 2
RGD ID: 1309447
Description: Predicted to enable carbohydrate binding activity and metal ion binding activity. Involved in neurotransmitter receptor localization to postsynaptic specialization membrane. Is active in glutamatergic synapse and synaptic cleft. Is extrinsic component of postsynaptic specialization membrane. Orthologous to human NPTX2 (neuronal pentraxin 2); INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC288475; Narp; neuro activity regulated petaxin; Neuronal activity regulated pentraxin; neuronal activity-regulated pentraxin; neuronal pentraxin II; neuronal pentraxin-2; NP-II; NP2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,151,136 - 15,162,045 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1215,151,136 - 15,162,045 (-)EnsemblGRCr8
mRatBN7.21210,037,435 - 10,048,345 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,037,435 - 10,048,345 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1210,838,309 - 10,849,215 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,461,552 - 11,472,458 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,485,258 - 10,496,168 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01212,014,638 - 12,025,547 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,013,911 - 12,025,549 (-)Ensemblrn6Rnor6.0
Rnor_5.01214,073,308 - 14,084,217 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41210,359,406 - 10,370,315 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1211,838,383 - 11,849,292 (-)NCBICelera
RGSC_v3.11210,389,235 - 10,559,203 (-)NCBI
Cytogenetic Map12p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP)
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
1,3,5-trinitro-1,3,5-triazinane  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methoxyethanol  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
butanal  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
chlorpyrifos  (EXP)
choline  (ISO)
cisplatin  (ISO)
clozapine  (EXP)
cocaine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (EXP)
disulfiram  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
fluoxetine  (EXP)
folic acid  (ISO)
fonofos  (ISO)
gefitinib  (ISO)
haloperidol  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
medroxyprogesterone acetate  (ISO)
methamphetamine  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-Nitrosopyrrolidine  (ISO)
nevirapine  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
silicon dioxide  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Differing mechanisms for glutamate receptor aggregation on dendritic spines and shafts in cultured hippocampal neurons. Mi R, etal., J Neurosci 2002 Sep 1;22(17):7606-16.
4. Synaptic clustering of AMPA receptors by the extracellular immediate-early gene product Narp. O'Brien RJ, etal., Neuron. 1999 Jun;23(2):309-23.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8786423   PMID:12453059   PMID:14678750   PMID:18057201   PMID:23751516   PMID:27986928   PMID:32396526  


Genomics

Comparative Map Data
Nptx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,151,136 - 15,162,045 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1215,151,136 - 15,162,045 (-)EnsemblGRCr8
mRatBN7.21210,037,435 - 10,048,345 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,037,435 - 10,048,345 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1210,838,309 - 10,849,215 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,461,552 - 11,472,458 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,485,258 - 10,496,168 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01212,014,638 - 12,025,547 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,013,911 - 12,025,549 (-)Ensemblrn6Rnor6.0
Rnor_5.01214,073,308 - 14,084,217 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41210,359,406 - 10,370,315 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1211,838,383 - 11,849,292 (-)NCBICelera
RGSC_v3.11210,389,235 - 10,559,203 (-)NCBI
Cytogenetic Map12p11NCBI
NPTX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38798,617,285 - 98,629,869 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl798,617,285 - 98,629,869 (+)Ensemblhg38GRCh38
GRCh37798,246,597 - 98,259,181 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36798,084,545 - 98,097,116 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34797,891,259 - 97,903,831NCBI
Celera792,941,625 - 92,954,210 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef792,845,666 - 92,858,931 (+)NCBIHuRef
CHM1_1798,176,644 - 98,189,227 (+)NCBICHM1_1
T2T-CHM13v2.0799,848,957 - 99,861,534 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2797,570,995 - 97,583,579 (+)NCBI
Nptx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395144,482,697 - 144,494,288 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5144,482,712 - 144,494,288 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385144,545,887 - 144,557,478 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5144,545,902 - 144,557,478 (+)NCBImm10GRCm38
MGSCv375145,306,756 - 145,318,347 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365144,799,430 - 144,811,005 (+)NCBIMGSCv36mm8
Celera5141,541,852 - 141,556,622 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map584.58NCBI
Nptx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546014,437,755 - 14,448,964 (+)Ensembl
ChiLan1.0NW_00495546014,437,755 - 14,448,932 (+)NCBIChiLan1.0ChiLan1.0
NPTX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26116,467,229 - 116,480,719 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17164,731,864 - 164,745,354 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0790,581,250 - 90,593,880 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
NPTX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1610,805,564 - 10,816,587 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl610,806,696 - 10,816,572 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha612,432,206 - 12,443,215 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0610,806,047 - 10,817,053 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl610,806,056 - 10,817,052 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1610,675,231 - 10,686,229 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0610,654,414 - 10,665,423 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0610,888,515 - 10,899,524 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nptx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344138,863,793 - 138,874,869 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367501,064,256 - 1,081,498 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367501,070,386 - 1,081,467 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPTX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl35,720,680 - 5,732,454 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.135,720,686 - 5,732,458 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.235,732,030 - 5,741,753 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NPTX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12814,537,837 - 14,550,504 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2814,537,787 - 14,550,266 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660701,630,433 - 1,643,102 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nptx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474032,125,715 - 32,136,659 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474032,125,693 - 32,136,671 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nptx2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1168,620,255 - 8,631,706 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nptx2
65 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:268
Count of miRNA genes:162
Interacting mature miRNAs:182
Transcripts:ENSRNOT00000001331
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1357337Gluco3Glucose level QTL 30.0004adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)12116966671Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)121186960016966542Rat
61334Gluco17Glucose level QTL 176.3adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)12116966671Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12115486827Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat

Markers in Region
RH142204  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21210,037,419 - 10,037,615 (+)MAPPERmRatBN7.2
Rnor_6.01212,014,623 - 12,014,818NCBIRnor6.0
Rnor_5.01214,073,293 - 14,073,488UniSTSRnor5.0
RGSC_v3.41210,359,391 - 10,359,586UniSTSRGSC3.4
Celera1211,838,368 - 11,838,563UniSTS
Cytogenetic Map12p11UniSTS
AU049050  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21210,041,606 - 10,041,753 (+)MAPPERmRatBN7.2
Rnor_6.01212,018,810 - 12,018,956NCBIRnor6.0
Rnor_5.01214,077,480 - 14,077,626UniSTSRnor5.0
RGSC_v3.41210,363,578 - 10,363,724UniSTSRGSC3.4
Celera1211,842,555 - 11,842,701UniSTS
Cytogenetic Map12p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 50 142 88 83 56 73 56 6 281 145 1 129 56 92 27 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000001331   ⟹   ENSRNOP00000001331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,151,136 - 15,162,045 (-)Ensembl
mRatBN7.2 Ensembl1210,037,435 - 10,048,345 (-)Ensembl
Rnor_6.0 Ensembl1212,013,911 - 12,025,549 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1212,015,090 - 12,016,639 (-)Ensembl
RefSeq Acc Id: NM_001034199   ⟹   NP_001029371
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,151,136 - 15,162,045 (-)NCBI
mRatBN7.21210,037,435 - 10,048,345 (-)NCBI
Rnor_6.01212,014,638 - 12,025,547 (-)NCBI
Rnor_5.01214,073,308 - 14,084,217 (-)NCBI
RGSC_v3.41210,359,406 - 10,370,315 (-)RGD
Celera1211,838,383 - 11,849,292 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001029371 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB46783 (Get FASTA)   NCBI Sequence Viewer  
  EDL89629 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001331
GenBank Protein P97738 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001029371   ⟸   NM_001034199
- Peptide Label: precursor
- UniProtKB: P97738 (UniProtKB/Swiss-Prot),   F1LR84 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001331   ⟸   ENSRNOT00000001331
Protein Domains
Pentraxin (PTX)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97738-F1-model_v2 AlphaFold P97738 1-432 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698423
Promoter ID:EPDNEW_R8948
Type:single initiation site
Name:Nptx2_1
Description:neuronal pentraxin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01212,025,532 - 12,025,592EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309447 AgrOrtholog
BioCyc Gene G2FUF-20044 BioCyc
Ensembl Genes ENSRNOG00000001006 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000001331 ENTREZGENE
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot
  Neuronal_Pentraxin_Related UniProtKB/Swiss-Prot
  Pentaxin_CS UniProtKB/Swiss-Prot
  Pentraxin-related UniProtKB/Swiss-Prot
NCBI Gene 288475 ENTREZGENE
PANTHER NEURONAL PENTRAXIN-2 UniProtKB/Swiss-Prot
  PENTRAXIN UniProtKB/Swiss-Prot
Pfam Pentaxin UniProtKB/Swiss-Prot
PhenoGen Nptx2 PhenoGen
PRINTS PENTAXIN UniProtKB/Swiss-Prot
PROSITE PTX_1 UniProtKB/Swiss-Prot
  PTX_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001006 RatGTEx
SMART PTX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot
UniProt A6K1H1_RAT UniProtKB/TrEMBL
  F1LR84 ENTREZGENE, UniProtKB/TrEMBL
  NPTX2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Nptx2  neuronal pentraxin 2  Nptx2  neuronal pentraxin II  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-19 Nptx2  neuronal pentraxin II  Nptx2  neuronal pentraxin 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Nptx2  neuronal pentraxin 2  Nptx2  neuronal pentraxin II  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-24 Nptx2  neuronal pentraxin II  Narp  neuro activity regulated petaxin  Data merged from RGD:3149 737654 APPROVED
2005-12-06 Nptx2  neuronal pentraxin II  Nptx2_predicted  neuronal pentraxin II (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Nptx2_predicted  neuronal pentraxin II (predicted)      Symbol and Name status set to approved 70820 APPROVED
2002-06-10 Narp  Neuronal activity regulated pentraxin      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression highly expressed at excitatory synapses on the dendritic shafts of cultured spinal and hippocampal neurons 625652
gene_process mediates aggregation of NMDA recptors in hippocampal interneurons indirectly through coupling to synaptic AMPA receptors 625652
gene_protein 55-kDa protein 625652